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VAGPDGGAGLRWGVEPMCAVLSEHGIAISPSTYYEWIAKTPTRREIRDAELVEIITAAREGKRKGRFVQT LGSRKLWIWLRGQGHDVARCTVERIMRENGWEGARYGSKHKTTVADSSHVRYPDLVDRRFYASAPNRLWV ADFTYVATWMGFVYVAFVIDAYSRRIVGWRAARSMTTDLVLDAIEHAFFTRTQDGTSLRGLIAHSDAGSQ YTSVAFTQRLIDEGVDPSVGSVGDALDNALAETTVGSFKNEVIRRQGPWRDVNQVELATAEWVVWFNTER PHEYLDDFTPEAVEKLHYDQKLTPPKAG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0665 | - | - | 100% (308) | integrase catalytic subunit |
M. gilvum PYR-GCK | Mflv_3221 | - | 3e-83 | 52.16% (301) | integrase catalytic subunit |
M. gilvum PYR-GCK | Mflv_2788 | - | 3e-83 | 52.16% (301) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2838c | - | 1e-78 | 51.07% (280) | transposase |
M. tuberculosis H37Rv | Rv3475 | - | 3e-86 | 51.82% (303) | transposase IS6110 |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2086c | - | 1e-23 | 49.57% (115) | putative transposase-like protein IS1601-D |
M. marinum M | MMAR_2548 | - | 1e-109 | 65.98% (291) | transposase, ISMyma03_aa2 |
M. avium 104 | MAV_5093 | - | 4e-72 | 48.14% (295) | transposase |
M. smegmatis MC2 155 | MSMEG_1721 | - | 4e-83 | 52.49% (301) | IS1137, transposase orfB |
M. thermoresistible (build 8) | TH_3317 | - | 6e-56 | 43.36% (286) | PUTATIVE Integrase, catalytic region |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_5973 | - | 3e-53 | 50.23% (215) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment MAB_2086c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5093|M.avium_104 ------------------------------------MAFIDANR------ TH_3317|M.thermoresistible__bu -----------------------------------MIAFIDAHR------ Mvan_5973|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2838c|M.bovis_AF2122/97 -------------------------------------------------- Rv3475|M.tuberculosis_H37Rv AEALAAGQRRIAKGERDFKDRVGFLRGRARPASTLITRFIADHQGHREGP Mflv_0665|M.gilvum_PYR-GCK -------------------------------------------MAGPDGG MMAR_2548|M.marinum_M -------------------------------------------------- MSMEG_1721|M.smegmatis_MC2_155 ------------------------------------MEFISAHQHMRVGV MAB_2086c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5093|M.avium_104 --DEFGVEPICTVLRSAGLQVAPST-YYANKTRT-PSARAQRDAVMRPVI TH_3317|M.thermoresistible__bu --DQFGVELICRVLRAAIAGFLTSRGYRAAKARP-PSERAMRDELLIAEL Mvan_5973|M.vanbaalenii_PYR-1 ---------------------MAPSTYYDVKSRC-PSARARRDAELGPAL Mb2838c|M.bovis_AF2122/97 -------------------MPIAPSTYYDHINRE-PSRRELRDGELKEHI Rv3475|M.tuberculosis_H37Rv DGLRWGVESICTQLT-ELGVPIAPSTYYDHINRE-PSRRELRDGELKEHI Mflv_0665|M.gilvum_PYR-GCK AGLRWGVEPMC-AVLSEHGIAISPSTYYEWIAKT-PTRREIRDAELVEII MMAR_2548|M.marinum_M -------------MLTEHGIKISPSTYYEWMKRT-PSKQQLRDEAVTASI MSMEG_1721|M.smegmatis_MC2_155 DGLKWGVESMC-AVLSEYGVTIAPSTYYAHRARQGPSKADWADAQVIDAI MAB_2086c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5093|M.avium_104 TQLWEDN-----YRVYGARKLWKAARRAGHDIGRDQIARLMREAGIAGVR TH_3317|M.thermoresistible__bu RTVHEQN-----FSVYGVKKMHHAMKRRGWRVGREQTRRLMRKAGLRGVQ Mvan_5973|M.vanbaalenii_PYR-1 RVIWEDN-----YRVYGAVKLWKAARRGGHDVGRDQVARLMRSLGIEGVR Mb2838c|M.bovis_AF2122/97 SRVHAAN-----YGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTT Rv3475|M.tuberculosis_H37Rv SRVHAAN-----YGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTT Mflv_0665|M.gilvum_PYR-GCK TAAREGKRKGRFVQTLGSRKLWIWLRGQGHDVARCTVERIMRENGWEGAR MMAR_2548|M.marinum_M KEFRE---RNPLNKTLGSRKVWIKLRGDGMDVARCTVERLMQANRWQGAR MSMEG_1721|M.smegmatis_MC2_155 WQLRQ---SQSLYRVLGARKTWIVLRTNGIDVSRCVVERVMREMGWRGAC MAB_2086c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_5093|M.avium_104 RGKRVRTTKPGPGAPRHPDLVGRDFTASAPNQLWVTDLTFVPTWAGVAYV TH_3317|M.thermoresistible__bu RGKPVFTTISDPAHCRPADLVNRQFSAEAPDRLWVADITFVRTWQGFCYT Mvan_5973|M.vanbaalenii_PYR-1 RGKRVTTTRADPAAPRHPDLVKRQFTATAPNQLWVTDLTFVPTWVGVAYV Mb2838c|M.bovis_AF2122/97 RGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYV Rv3475|M.tuberculosis_H37Rv RGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYV Mflv_0665|M.gilvum_PYR-GCK YGSKHKTTVADSSHVRYPDLVDRRFYASAPNRLWVADFTYVATWMGFVYV MMAR_2548|M.marinum_M YGGAPKTTIQDEKAQRATDLVDRVFAAPAPNRLWVADFTYCPTWAGMVYV MSMEG_1721|M.smegmatis_MC2_155 KRRRVRTTVADPAATRAPDRVRRNFVAGAPDRLWVADFTYCRTRAGWAYT MAB_2086c|M.abscessus_ATCC_199 --------------------------------------------MPGLTC MAV_5093|M.avium_104 CFLTDAFSRMIIGWRVASHMRTT-VVLDTIEMARWSRGK----MLAGLRC TH_3317|M.thermoresistible__bu AFVTDACTKAIKGWAVAASMRTEDLPLEAFNHAVWHSDS----DLSELIH Mvan_5973|M.vanbaalenii_PYR-1 CFIVDAFSRLIVGWRAASNMRTT-MVLDALEMARWSRGN----TLSGLRC Mb2838c|M.bovis_AF2122/97 AFVTDAYARRILGWRVASTMATS-MVLDAIEQAIWTRQQEGVLDLKDVIH Rv3475|M.tuberculosis_H37Rv AFVTDAYARRILGWRVASTMATS-MVLDAIEQAIWTRQQEGVLDLKDVIH Mflv_0665|M.gilvum_PYR-GCK AFVIDAYSRRIVGWRAARSMTTD-LVLDAIEHAFFTRTQDG-TSLRGLIA MMAR_2548|M.marinum_M AFVIDAFARRVIGWRAATSMKTA-LVIDALEHAFFTRAQEGFTDLSGLVA MSMEG_1721|M.smegmatis_MC2_155 AFVTDVYARKIVGWKVATEMTQK-LVTDAIDHAIDTRKRSGAASLDSLIH : : MAB_2086c|M.abscessus_ATCC_199 HSDAGSQFTSIRYGERLAEIGAVPSIGTIGDSYDNAL-ETVNGYYKAELI MAV_5093|M.avium_104 HSDAGSQFTSIRYSERLAEIGAVPSIGTVGDSFDNALAETVNGYYKAELI TH_3317|M.thermoresistible__bu HSDRGSQYLSLTYTDRLAELGIAPSVGSRGDSYDNALAEAVNAAYKTELI Mvan_5973|M.vanbaalenii_PYR-1 HSDAGSQFTSIRYGERLAELGAVPSIGSVGDSFDNALAERAC------LI Mb2838c|M.bovis_AF2122/97 HTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELI Rv3475|M.tuberculosis_H37Rv HTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELI Mflv_0665|M.gilvum_PYR-GCK HSDAGSQYTSVAFTQRLIDEGVDPSVGSVGDALDNALAETTVGSFKNEVI MMAR_2548|M.marinum_M HSDAGSQYTSIAFTTRLIDAGIDASVGSVADAYDNALAETTVGSFKNELI MSMEG_1721|M.smegmatis_MC2_155 HSDAGSQYTAVAFTERLAAEGILPSVGSVGDSFDNALAESVNSSYKTELI *:* ***: :: : ** * .*:*: ..: **** * :* MAB_2086c|M.abscessus_ATCC_199 YGPVRTRPWKTVEDVELATLSWVYWHNTSRLHSYLNDIPPTEFEAAFY-D MAV_5093|M.avium_104 YGPARPGPWKTVEDVELATLSWVHWHNTSRLHGYLNDVPPAEFEAAFY-A TH_3317|M.thermoresistible__bu N---RGKPWRSVDDVELATAGWVAWYNQERLHEALGYVPPAEYEAALTGT Mvan_5973|M.vanbaalenii_PYR-1 D----------------CVSGWA--------------------------- Mb2838c|M.bovis_AF2122/97 K---PGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQ Rv3475|M.tuberculosis_H37Rv K---PGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQ Mflv_0665|M.gilvum_PYR-GCK R---RQGPWRDVNQVELATAEWVVWFNTERPHEYLDDFTPEAVEKLHYDQ MMAR_2548|M.marinum_M R---RQGPWRDVDHVEIGTLNWVDWFNNERPHEYLADLTPTQAEALHYRH MSMEG_1721|M.smegmatis_MC2_155 D---RQPLYPGATELALGTAEWVAFYNRQRPNGYCQDLTPDRAEALYYHR . *. MAB_2086c|M.abscessus_ATCC_199 AHGTDQPLAGIQ-- MAV_5093|M.avium_104 TKRTDHPLVEIQ-- TH_3317|M.thermoresistible__bu SHPASQPTPALATN Mvan_5973|M.vanbaalenii_PYR-1 -------------- Mb2838c|M.bovis_AF2122/97 RQRPAAG------- Rv3475|M.tuberculosis_H37Rv RQRPAAG------- Mflv_0665|M.gilvum_PYR-GCK KLTPPKAG------ MMAR_2548|M.marinum_M KSSLAAAG------ MSMEG_1721|M.smegmatis_MC2_155 QRHPHAEEALR---