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SAGVVFRQRFPGTARSLSQWRANWRDLGDQARFYGQSISSTVQAATTYRAEVLRQIAAIGLGAGSLAVVG GTVAVVAFLNLSTSAALASQAYNQMSQVGVEALAGFTSAYVNVRLATPASSAFAFAATIGAGTTAQLGAM KINEEIDALAVMGIRPIAYLASTRLLAGVIVVVPLYCVALLMSFFSVRVITTAFYGQGSGVFDHYFDTFL NPQAVFFSFAVTVAAALVIMLIHTYYGLNATGGPAGVGEAVGRATRTSLIASQMVILLVTLALYGQTGTF NYAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0653 | - | - | 100% (285) | hypothetical protein Mflv_0653 |
| M. gilvum PYR-GCK | Mflv_2100 | - | 6e-93 | 62.45% (261) | hypothetical protein Mflv_2100 |
| M. gilvum PYR-GCK | Mflv_2507 | - | 2e-79 | 48.77% (285) | hypothetical protein Mflv_2507 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0174 | yrbE1B | 3e-75 | 49.30% (286) | integral membrane protein YRBE1B |
| M. tuberculosis H37Rv | Rv1965 | yrbE3B | 5e-82 | 57.25% (262) | integral membrane protein YrbE3b |
| M. leprae Br4923 | MLBr_02588 | yrbE1B | 3e-75 | 48.77% (285) | hypothetical protein MLBr_02588 |
| M. abscessus ATCC 19977 | MAB_4154c | - | 1e-74 | 48.90% (272) | hypothetical protein MAB_4154c |
| M. marinum M | MMAR_4050 | yrbE3B_1 | 2e-89 | 56.88% (276) | integral membrane protein YrbE3B_1 |
| M. avium 104 | MAV_2060 | - | 7e-85 | 55.77% (260) | TrnB2 protein |
| M. smegmatis MC2 155 | MSMEG_0345 | - | 1e-93 | 62.31% (268) | hypothetical protein MSMEG_0345 |
| M. thermoresistible (build 8) | TH_3332 | - | 3e-98 | 65.15% (264) | PUTATIVE protein of unknown function DUF140 |
| M. ulcerans Agy99 | MUL_3917 | yrbE3B_1 | 1e-89 | 56.88% (276) | integral membrane protein YrbE3B_1 |
| M. vanbaalenii PYR-1 | Mvan_0499 | - | 1e-156 | 100.00% (285) | hypothetical protein Mvan_0499 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0653|M.gilvum_PYR-GCK -MSAGVVFRQRFPGTARSLSQW----RANWRDLGDQARFYGQSISSTVQA
Mvan_0499|M.vanbaalenii_PYR-1 -MSAGVVFRQRFPGTARSLSQW----RANWRDLGDQARFYGQSISSTVQA
TH_3332|M.thermoresistible__bu -----VKIRRRA--------------RSSWRRIGEQTRFYGTTIVSLFDA
MMAR_4050|M.marinum_M --MTAVAAGSRWRGVRHKLDGW----VAGWNQIGTQTKFFGRTLRSIHYM
MUL_3917|M.ulcerans_Agy99 --MTAVAAGSRWRGVRHKLDGW----VAGWNQIGTQTKFFGRTLRSIHYM
MSMEG_0345|M.smegmatis_MC2_155 --------------MSNRLDRV----RAAWDGIGVQTQFYARAIGSIGDA
Rv1965|M.tuberculosis_H37Rv ---------------MTAAKAL----VSEWNRMGSQMRFFVGTLAGIPDA
MAB_4154c|M.abscessus_ATCC_199 MSGPYLSTHTVTSYTVRYMRGL----GRSFDKFGEQALFYAQSLSYIPAA
MAV_2060|M.avium_104 MTEIAREPSRFAALGPR----L----VESTRKLGEQTVFYGQSLTAIADA
Mb0174|M.bovis_AF2122/97 -MSTAAVLRARFPRAVANLRQYGGAAARGLDEAGQLTWFALTSIGQIAHA
MLBr_02588|M.leprae_Br4923 -MSTAAVLRARFPRAAANLNRYGGAAARGIDDIGQMSWFGLIALGNIPNA
* * ::
Mflv_0653|M.gilvum_PYR-GCK ATTYRAEVLRQIAAIGLGAGSLAVVGGTVAVVAFLNLSTSAALASQAYNQ
Mvan_0499|M.vanbaalenii_PYR-1 ATTYRAEVLRQIAAIGLGAGSLAVVGGTVAVVAFLNLSTSAALASQAYNQ
TH_3332|M.thermoresistible__bu CVYYRAELLRQVAAMSLGTGALAAIGGTVAVVAFLTMSTGGLIAAQGYNQ
MMAR_4050|M.marinum_M LIHYRVELIRLIAQMGLGAGALMVIGGTVAIVGFLTVTTGALVAVQGYSD
MUL_3917|M.ulcerans_Agy99 LIHYRVELIRLIAQMGLGAGALMVIGGTVAIVGFLTVTTGALVAVQGYSD
MSMEG_0345|M.smegmatis_MC2_155 AMNYRTELIRLIATMGLGAGALAVVGGTVAIVGFLTMTTGALVAVQGYNQ
Rv1965|M.tuberculosis_H37Rv LMHYRGELLRVIAQMGLGTGVLAVIGGTVAIVGFLAMTTGAIVAVQGYNQ
MAB_4154c|M.abscessus_ATCC_199 LTKYRKETIRVLAEITMGTGALVMIGGTVGVAVFLTLASGGVIAVQGYSS
MAV_2060|M.avium_104 IRRYPGELLRLIAEMGMGTGALAVIGGTVGIIGFLTLTTGALVAVQGYDT
Mb0174|M.bovis_AF2122/97 LRYYRKETLRLIAQIGMGTGAMAVVGGTVAIVGFVTLSGSSLVAIQGFAS
MLBr_02588|M.leprae_Br4923 LSRYRKETLRLIAQIGMGTGAMAVVGGTAAIVGFVTLSGSSLVAIQGFAS
* * :* :* : :*:* : :***..: *: :: .. :* *.:
Mflv_0653|M.gilvum_PYR-GCK MSQVGVEALAGFTSAYVNVRLATPASSAFAFAATIGAGTTAQLGAMKINE
Mvan_0499|M.vanbaalenii_PYR-1 MSQVGVEALAGFTSAYVNVRLATPASSAFAFAATIGAGTTAQLGAMKINE
TH_3332|M.thermoresistible__bu FSQVGVDALVGFASAFLNTRLITPTTAAIALAATIGAGATAQLGAMRVNE
MMAR_4050|M.marinum_M FSELGVEALTGFASAFFNVRLIAPATTAIALSATIGAGATAQLGAMRIND
MUL_3917|M.ulcerans_Agy99 FSELGVEALTGFASAFFNVRLIAPATTAIALSATIGAGATAQLGAMRIND
MSMEG_0345|M.smegmatis_MC2_155 FASVGVEALTGFASAFFNVRLIAPGTTAVALSATIGAGATAQLGAMRINE
Rv1965|M.tuberculosis_H37Rv FASVGVEALTGFASAFFNTREIQPGTVMVALAATVGAGTTAALGAMRINE
MAB_4154c|M.abscessus_ATCC_199 LGNIGIEALTGFLSAFLNVRIVAPVVAGIAMAATIGAGTTAQLGAMRVAE
MAV_2060|M.avium_104 LSNIGVEALTGFLSAFLNVRMIAPCTAGLALAATIGAGATAQLGAMRINE
Mb0174|M.bovis_AF2122/97 LGNIGVEAFTGFFAALINVRIAGPVVTGVALAATVGAGATAELGAMRISE
MLBr_02588|M.leprae_Br4923 LGAIGVEAFTGFFAALINVRIAAPVITGIVMAATVGAGATAELGAMRISE
:. :*::*:.** :* .*.* * ..::**:***:** ****:: :
Mflv_0653|M.gilvum_PYR-GCK EIDALAVMGIRPIAYLASTRLLAGVIVVVPLYCVALLMSFFSVRVITTAF
Mvan_0499|M.vanbaalenii_PYR-1 EIDALAVMGIRPIAYLASTRLLAGVIVVVPLYCVALLMSFFSVRVITTAF
TH_3332|M.thermoresistible__bu EIDALEVMGVRSIAYLASTRLVAGVVVVLPLYSVALILAYFAARFGTTAI
MMAR_4050|M.marinum_M EIDALEVMGIRTIAFLAASRVVAGLLVVIPLYCVGVLASFWAARFGTTVL
MUL_3917|M.ulcerans_Agy99 EIDALEVMGIRTIAFLAASRVVAGLLVVIPLYCVGVLASFWAARFGTTVL
MSMEG_0345|M.smegmatis_MC2_155 EIDALEVIGIRSVSYLASTRVAAGVIVVIPLYCVAVIMSFISSRLGTTVI
Rv1965|M.tuberculosis_H37Rv EIDALEVIGIRSISYLASTRVLAGVVVAVPLFCVGLMTAYLAARVGTTAI
MAB_4154c|M.abscessus_ATCC_199 EIDALETMAVHAISYLVSTRLVAGLIAIIPLYSLSVLAAFFASRATTVMI
MAV_2060|M.avium_104 EIDALEVMGIRAVTYLASTRIIAGILVVIPLYAVAVLMSFIAAKLLTIYV
Mb0174|M.bovis_AF2122/97 EIDALEVMGIKSISFLASTRIMAGLVVIIPLYALAMIMSFLSPQITTTVL
MLBr_02588|M.leprae_Br4923 EIDALEVMSIKSISFLVTTRILAGLVVIVPLYAVAMIMAFLSPHIITTVL
***** .:.::.:::*.::*: **::. :**:.:.:: :: : : * .
Mflv_0653|M.gilvum_PYR-GCK YGQGSGVFDHYFDTFLNPQAVFFSFAVTVAAALVIMLIHTYYGLNATGGP
Mvan_0499|M.vanbaalenii_PYR-1 YGQGSGVFDHYFDTFLNPQAVFFSFAVTVAAALVIMLIHTYYGLNATGGP
TH_3332|M.thermoresistible__bu YGQSSGVYNHYFNTFLVPADVIRSFTVTTVAAATVMLIHTYYGYTASGGP
MMAR_4050|M.marinum_M YSQATGVYDHYFRTFLNPTDLVWSFVQCIALSLVIMLVHTYYGYTARGGP
MUL_3917|M.ulcerans_Agy99 YSQATGVYDHYFRTFLNPTDLVWSFVQCIALSLVIMLVHTYYGYTARGGP
MSMEG_0345|M.smegmatis_MC2_155 YGQGSGVYDHYFNTFLNTNDLLWSFGQSVAITVVIMLVHTYYGYTASGGP
Rv1965|M.tuberculosis_H37Rv YGQGSGVYDHYFNTFLRPTDVLWSSVEVVVVALMIMLVCTYYGYAAHGGP
MAB_4154c|M.abscessus_ATCC_199 NGQSPGVYDHYFNTFLVPTDLLWSFLQAIVMSVVVMLVHTSYGFNASGGP
MAV_2060|M.avium_104 YGQSKGVYEHYFSTFLRPNDLLWSFFSALAMATGVMVVHTYYGFTATGGP
Mb0174|M.bovis_AF2122/97 YGQSNGTYEHYFQTFLRPDDVFWSFLEALIITAIVMVSHCYYGYAAGGGP
MLBr_02588|M.leprae_Br4923 YGQSNGTYEHYFRTFLRPDDVFWSFLEAVIITAVVMITHCYYGYTANGGP
.*. *.::*** *** . :. * : :*: ** * ***
Mflv_0653|M.gilvum_PYR-GCK AGVGEAVGRATRTSLIASQMVILLVTLALYGQTGTFNYAG
Mvan_0499|M.vanbaalenii_PYR-1 AGVGEAVGRATRTSLIASQMVILLVTLALYGQTGTFNYAG
TH_3332|M.thermoresistible__bu AGVGEAVGRATRTSLVATALLILFVSLAIYGQTGQFNFSG
MMAR_4050|M.marinum_M AGVGEAVGRAVRTSLIFSAFVLVMISLAVYGQSGNFNLAG
MUL_3917|M.ulcerans_Agy99 AGVGEAVGRAVRTSLIFSAFVLVMISLAVYGQSGNFNLAG
MSMEG_0345|M.smegmatis_MC2_155 AGVGEAVGRAVRTSLIVAAIVVVMISLALYGQSGNFHLAG
Rv1965|M.tuberculosis_H37Rv AGVGEAVGRAVRASMVVASIAILVMTLAIYGQSPNFHLAT
MAB_4154c|M.abscessus_ATCC_199 VGVGVAVGQAVRTSLIVVVLVTLFISLAVYGGSGNFNLSG
MAV_2060|M.avium_104 AGVGEAVGRSVRSSMIVTAFVCLMISLSVYGQSGNFNLSG
Mb0174|M.bovis_AF2122/97 VGVGEAVGRSMRFSLVSVQVVVLFAALALYGVDPNFNLTV
MLBr_02588|M.leprae_Br4923 VGVGEAVGRSMRFSLVSVQVVVLSATLALYGVDPNFALTV
.*** ***:: * *:: . : :*::** * :