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MSERLACKAVGLARSTYRRLPLGQTPDDPDAEMRAWLRSYATKHPCHGFRRAWAALRYDEGREVNRKKIH RLWREEGLQVRVHSPRKRAGVSSVPPILADAPGVVWAIDFQFDSTVDGKAIKIASMIDEHTRESLLNLVE RSITGEALVAELTKVFAAAGGPPKVLRMDNGPEMVSQALQRFCENRTGMVYIPPGCPWDNGYIESFNNRL RRECLNRNYWNTLFEARVVIGDFKHEHNHRHRHSALGYLTPAEYAAACRCTHTPGVCCMIR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0603 | - | - | 100% (271) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_4763 | - | 7e-58 | 45.59% (272) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_4752 | - | 7e-58 | 45.59% (272) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2812 | - | 4e-05 | 25.43% (173) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 2e-07 | 26.95% (167) | transposase |
| M. marinum M | MMAR_4846 | - | 1e-83 | 58.30% (259) | transposase, ISMyma01_aa2 |
| M. avium 104 | MAV_3240 | - | 2e-08 | 24.78% (230) | transposase |
| M. smegmatis MC2 155 | MSMEG_1866 | - | 1e-138 | 85.39% (267) | transposase B |
| M. thermoresistible (build 8) | TH_4372 | - | 7e-08 | 26.62% (154) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | MUL_2691 | - | 6e-08 | 42.11% (57) | transposase ISMmr01_aa2-like |
| M. vanbaalenii PYR-1 | Mvan_1111 | - | 4e-57 | 45.22% (272) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0603|M.gilvum_PYR-GCK --------------------------MSERLACKAVGLAR-------STY
MSMEG_1866|M.smegmatis_MC2_155 -------------------MLTTTMGMSERLACKAVGLAR-------STC
MMAR_4846|M.marinum_M -----------------------MLGVSERFACRVTGQHR-------ATQ
MUL_2691|M.ulcerans_Agy99 ------------MRTGTVRHLQRVLAVSERFACRVTGQQR-------ATQ
Mvan_1111|M.vanbaalenii_PYR-1 -------------------MLRERFGVSERRACTVVGLHR-------STM
MAV_3240|M.avium_104 ------------------------MALSTYYDAKARVPSA-------RAL
MAB_2088|M.abscessus_ATCC_1997 ---------------------------MTRRVLKLARQPY-------YRW
TH_4372|M.thermoresistible__bu -------------VSRFELIAAECAHHDVSKLAELLGVSRSGYYAWAARQ
Rv2812|M.tuberculosis_H37Rv MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASRE
Mflv_0603|M.gilvum_PYR-GCK RRLPLGQTPDDPDAEMRAWLRSYATKHPCHGFRR--------------AW
MSMEG_1866|M.smegmatis_MC2_155 RRLPLAETPADPDAEMRGWLRSYATKHPCHGFRR--------------AW
MMAR_4846|M.marinum_M RHEPVAGTPADPDAALREWLRDYANKHPRRGFRP--------------AY
MUL_2691|M.ulcerans_Agy99 RHESCAAPSEGPDGALRDWLRQYAKDHPRRGFRP--------------AY
Mvan_1111|M.vanbaalenii_PYR-1 RLTP--APIATEEAELRAWLRRFSTDRPRWGWRR--------------AA
MAV_3240|M.avium_104 RDAVLGPALC----------QLWKDNYCVYGARK--------------LW
MAB_2088|M.abscessus_ATCC_1997 RANPITDAELVEAYRANALFDAHGED-PEFGYRY--------------LV
TH_4372|M.thermoresistible__bu RRVELSPRQQWRRDLEVKILAHWQASGRTYGSPR--------------IT
Rv2812|M.tuberculosis_H37Rv HTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEVLELA
:
Mflv_0603|M.gilvum_PYR-GCK AALRYDEGREVNRKKIHRLWREEGLQVRV-HSPRKRAG-VSSVPP-----
MSMEG_1866|M.smegmatis_MC2_155 AALRYDERREVNKKKIHRLWREEGLQVRV-HSPRKRAG-VSSIPP-----
MMAR_4846|M.marinum_M HDARGEG-WEVNHKKVQRLWREEGLRVPQ-RRKRKRHG-TSTAPPE----
MUL_2691|M.ulcerans_Agy99 YDVRAE----------TALLRK----------------------------
Mvan_1111|M.vanbaalenii_PYR-1 KMARKAG-WKANNKRIRRLWREEGLRVPQ-RRRKKRLTGIGVAVGA----
MAV_3240|M.avium_104 KTARRDG-HDVGRDQVARLMRAAGIEGVR-RGKRVRTTKADPAAARH--P
MAB_2088|M.abscessus_ATCC_1997 EEAREAG-EPMAERTAWRICSQQQLWSVF-GKKRGKNG--KPGPPVH--D
TH_4372|M.thermoresistible__bu ADLHAEG-VGVSENTVAKIMAEMGIEGISPRTFKVKTTQVDPTASFP--P
Rv2812|M.tuberculosis_H37Rv VALRREN-PQRTAAAIRRILRTQLGWAPDERTLQRNFHRLGLTGATTGSA
: :
Mflv_0603|M.gilvum_PYR-GCK ------ILADAPGVVWAIDFQFDSTVDGKAIKIASMIDEHTRESLLNLVE
MSMEG_1866|M.smegmatis_MC2_155 ------IEADAPNVVWAIDFQFDSTIDGKAIKIASMIDEHTRVSLLNIVE
MMAR_4846|M.marinum_M ------VVADAPDRVWAVDFQFDVTTDGRPIKIVSIIDEHTRECLGGMVE
MUL_2691|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1111|M.vanbaalenii_PYR-1 ------MSPIRPNVIWAMDFQFDTTADGRILKMLNVIDEFTREALAIEVD
MAV_3240|M.avium_104 DLVHRNFAAAAPNQLWVTDLTFVPTWAG-VAYVCFIIDAHSRMIVGWRVA
MAB_2088|M.abscessus_ATCC_1997 DLVQRDFTAETPNMLWLSDITEHYTGDG-KLYLCAIKDAFSNRIVGYSID
TH_4372|M.thermoresistible__bu DRVGRAFDQGRLDAVWTSDITYLTCGEG-DAYLCAIRDEHSRRVLGWSLA
Rv2812|M.tuberculosis_H37Rv PAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSRLVPGYRWG
Mflv_0603|M.gilvum_PYR-GCK RSITGEALVAELTKVFAAAGGPPKVLRMD--NGPEMVSQALQRFCEN-RT
MSMEG_1866|M.smegmatis_MC2_155 RSITADRLVEELKKVFVAAGGPPRVLRMD--NGPEFISQALQQFCDG-RI
MMAR_4846|M.marinum_M RSITGDHLTEELGRIAAGRGALPAVLRCD--NGPELACSAMADWAEG-QV
MUL_2691|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1111|M.vanbaalenii_PYR-1 RAINADGVVDVLDRLALTHG-APHYVRFD--NGPEFVTHAVSDWCRFNSA
MAV_3240|M.avium_104 SHMRTSMVLDALEMARWSRGTTLQDLICHSDAGSQFTSIRYGERLAEIGT
MAB_2088|M.abscessus_ATCC_1997 SRMKSRLATAALRNAVGRRGVVAGCVVHTD-RGSQFRSRKFVQALHHHGM
TH_4372|M.thermoresistible__bu DHMRTELVEAAVDAAVFTRAGHVAGTVMHSDRGSQFTSYDMAQACTRHGL
Rv2812|M.tuberculosis_H37Rv HAEDTVRLAAALRPALASRGVPNAVYVDN---GSPYVDAWLLRACAKLGV
Mflv_0603|M.gilvum_PYR-GCK GMVYIPPGCPWDNGYIESFNNRLRRECLN----------RNYWNTLFEAR
MSMEG_1866|M.smegmatis_MC2_155 GMSYIPPGTPWNNGHIESFNNRLRKECLN----------RNHWNTLLEAR
MMAR_4846|M.marinum_M GLHFIPPGEPWRNGYVESFNSRIRDECLN----------INSFWSLAQAR
MUL_2691|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1111|M.vanbaalenii_PYR-1 GSLFIDPGSPWQNAWIESFNGRLRDELLN----------SWRFDSLLEAR
MAV_3240|M.avium_104 VPSIGTVGDSFDNALAETVNGYYKAELIYGPAR------SRPWKTVEDVE
MAB_2088|M.abscessus_ATCC_1997 VGSMGRVGAAGDNAAMESFFSLLQKNVLD----------RRRWATREELR
TH_4372|M.thermoresistible__bu LRSMGATGICWDNAGSESLWSTVKHEYYK----------RHAFTTYANLT
Rv2812|M.tuberculosis_H37Rv RLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELN
Mflv_0603|M.gilvum_PYR-GCK VVIGDFKH-EHNHRHRHSALGYLTPAEYAAACRCTHTPGVCCMIR-----
MSMEG_1866|M.smegmatis_MC2_155 VVIGDFKD-EHNHRHRHSALGYRTPAEYAAVCSCTHTP-VACSIN-----
MMAR_4846|M.marinum_M VVIGDWKH-EYNHHRRHSSLGYLPPARYAAACTHR---------------
MUL_2691|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1111|M.vanbaalenii_PYR-1 VIIEDWRC-DYNANRPHSAHGELTPAEFALQWTTTHQPQVA---------
MAV_3240|M.avium_104 LATLSWVH-WHNTSRLHSYLGDIPPTEFEAAFYDAYRTDQPLIGIQ----
MAB_2088|M.abscessus_ATCC_1997 IAIVTWIERTYHRRRRQGALGRLTPVEYEAIMTTTASQAA----------
TH_4372|M.thermoresistible__bu AGLDNYIR-FYNHERRHSSLGMISPIDFDLSLDILLSTQV----------
Rv2812|M.tuberculosis_H37Rv RLFTAWVETVYHRS-VHSETGQTPLARWSAGGPIPLPAPETLTEAFLWEE
Mflv_0603|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1866|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4846|M.marinum_M --------------------------------------------------
MUL_2691|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1111|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3240|M.avium_104 --------------------------------------------------
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4372|M.thermoresistible__bu --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv HRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMR
Mflv_0603|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1866|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4846|M.marinum_M --------------------------------------------------
MUL_2691|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1111|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3240|M.avium_104 --------------------------------------------------
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4372|M.thermoresistible__bu --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv RAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYT
Mflv_0603|M.gilvum_PYR-GCK ------------------------
MSMEG_1866|M.smegmatis_MC2_155 ------------------------
MMAR_4846|M.marinum_M ------------------------
MUL_2691|M.ulcerans_Agy99 ------------------------
Mvan_1111|M.vanbaalenii_PYR-1 ------------------------
MAV_3240|M.avium_104 ------------------------
MAB_2088|M.abscessus_ATCC_1997 ------------------------
TH_4372|M.thermoresistible__bu ------------------------
Rv2812|M.tuberculosis_H37Rv ALTGAADQIPGQLDLLTGQEAQPK