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AITENREIVIEATRDEILAVLYDLESLTEWSSAHQTVEILERDEEGRPKRSRQVVKIVGVSDDQILDYHV YDDGVGWTLVRSDQQRAQEARYRLTQEGESTRVRLELMVDLKAPLPGFLVKKGAKGLMDTATHGLRKRVL KIKG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0509 | - | - | 100% (145) | cyclase/dehydrase |
| M. gilvum PYR-GCK | Mflv_1678 | - | 3e-37 | 48.95% (143) | cyclase/dehydrase |
| M. gilvum PYR-GCK | Mflv_1679 | - | 1e-30 | 45.07% (142) | cyclase/dehydrase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0877 | - | 2e-40 | 52.08% (144) | hypothetical protein Mb0877 |
| M. tuberculosis H37Rv | Rv0854 | - | 2e-40 | 52.08% (144) | hypothetical protein Rv0854 |
| M. leprae Br4923 | MLBr_00889 | - | 3e-18 | 36.36% (132) | hypothetical protein MLBr_00889 |
| M. abscessus ATCC 19977 | MAB_0831 | - | 4e-35 | 48.94% (141) | hypothetical protein MAB_0831 |
| M. marinum M | MMAR_4682 | - | 4e-37 | 50.69% (144) | hypothetical protein MMAR_4682 |
| M. avium 104 | MAV_2785 | - | 5e-56 | 71.53% (144) | cyclase/dehydrase superfamily protein |
| M. smegmatis MC2 155 | MSMEG_5736 | - | 1e-37 | 47.92% (144) | cyclase/dehydrase |
| M. thermoresistible (build 8) | TH_2031 | - | 1e-33 | 43.45% (145) | cyclase/dehydrase |
| M. ulcerans Agy99 | MUL_0301 | - | 1e-37 | 50.69% (144) | hypothetical protein MUL_0301 |
| M. vanbaalenii PYR-1 | Mvan_5073 | - | 1e-36 | 47.55% (143) | cyclase/dehydrase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0509|M.gilvum_PYR-GCK ----------MAITENREIVIEATRDEILAVLYDLESLTEWSSAHQTVEI
MAV_2785|M.avium_104 ----------MAITDSREVVIEATPEEILDVLFDLESLTEWSPAHQKVEV
MSMEG_5736|M.smegmatis_MC2_155 ----------MATSDSREVLIEASPEEILDVIADVESTPSWSPQYTHAEI
Mvan_5073|M.vanbaalenii_PYR-1 MATSVVYGRAMATKDSREVVIEATPEQILDVIADVEATPTWSPQYQKAEI
TH_2031|M.thermoresistible__bu ----------MAVSDSRDVVIDATPAQILDVIADVAAVPEWSPQYLSAEV
Mb0877|M.bovis_AF2122/97 ----------MAIKESRDIVIEASPEEILDVIADFEAMTEWSPAHQSVEI
Rv0854|M.tuberculosis_H37Rv ----------MAIKESRDIVIEASPEEILDVIADFEAMTEWSPAHQSVEI
MMAR_4682|M.marinum_M ----------MAIKETRDIVIEASPQEILDVIADFEAMPGWSSPHQSAEI
MUL_0301|M.ulcerans_Agy99 ----------MAIKETRDIVIEASPQEILDVIADFEAMPEWSSPHQSAEI
MAB_0831|M.abscessus_ATCC_1997 ----------MATSDTREIVIEATPEQIMDVIADFEVLPKWSSAHQSSTV
MLBr_00889|M.leprae_Br4923 ----------MADKTTQTFYIDANPGEVMKTIADIESYPQWISEYKEVEV
** . .: . *:*. ::: .: *. . * . : :
Mflv_0509|M.gilvum_PYR-GCK LERDEEGRPKRSRQVVKIVGVSDDQILDYHVYDD--GVGWTLVRSDQQRA
MAV_2785|M.avium_104 LERDEENHPIRSRQVVKLVGISDEQELAYTIYDD--GVGWTLVSSKQQRA
MSMEG_5736|M.smegmatis_MC2_155 TERYDDGRPRRAKMTVKAAGLTDDQVIEYTWSEN--KVSWTLVSAGQLKA
Mvan_5073|M.vanbaalenii_PYR-1 LDRYDNGRPKQVRMTVKAAGLTDEQVIEYTWGDN--EVSWTLVSATQLKA
TH_2031|M.thermoresistible__bu LDAHPDGRPRRVKMKVKAAGLTDEQIVDYTWTDH--SAAWTLVSAGQLRS
Mb0877|M.bovis_AF2122/97 LETGDDGRPSKVKMKVKTAGITDEQVVAYSWTDR--SVRWTLVSSTQQRS
Rv0854|M.tuberculosis_H37Rv LETGDDGRPSKVKMKVKTAGITDEQVVAYSWTDR--SVRWTLVSSTQQRS
MMAR_4682|M.marinum_M LETGADGRPSQVKMKVKTAGITDEQVVAYSWGDN--KVNWSLVSSGQQRS
MUL_0301|M.ulcerans_Agy99 FETGADGRPSQVKMKVKTAGITDEQVVAYSWGDN--KVNWSLVSSGQQRS
MAB_0831|M.abscessus_ATCC_1997 LTTGEDGRPHQVTMKVKTAGITDEQTVAYTWGPD--TVSWTLVKASQQRR
MLBr_00889|M.leprae_Br4923 LEVDDEDFPKRARMLMDAKIFKDTLIMSYDWTADHQSVSWILESSSLLKS
:. * : :. ..* : * . * * : :
Mflv_0509|M.gilvum_PYR-GCK QEARYRLTQEGESTRVRLELMVDLKAPLPGFLVKKGAKGLMDTATHGLRK
MAV_2785|M.avium_104 QQGRYTLTPEGDATRVHFELTVDLVMPVPGFLIKKGSKSLMDTATEGLRK
MSMEG_5736|M.smegmatis_MC2_155 QDASYTLTPQGDKTKVRFDISIDLSVPLPGFIVKRTMKGGVETATDGLRK
Mvan_5073|M.vanbaalenii_PYR-1 QDAGYTLTPAGDKTKVKFDIAIDLSVPLPGFIIKRTIKGGVETATEGLRK
TH_2031|M.thermoresistible__bu QDAKYTLRPDGTRTKVTFEITVDPSVPLPGFVLKRAMRGAMETATDGLRK
Mb0877|M.bovis_AF2122/97 QDGKYELTPKGDNTLVQFEITVDPQVPLPGFVLKRAIKGTIDTATEALRS
Rv0854|M.tuberculosis_H37Rv QDGKYELTPKGDNTLVQFEITVDPQVPLPGFVLKRAIKGTIDTATEALRS
MMAR_4682|M.marinum_M QEGSYLLTPEGDKTRVKLELAVDAVVPLPGFVLKRAVKGTVESGLDELRK
MUL_0301|M.ulcerans_Agy99 QEGSYLLTPEGDKTRVKLELAVDAVVPLPGFVLKRAVKGTVESGLDELRK
MAB_0831|M.abscessus_ATCC_1997 QDGKYTFTPQGDKTHVKFELTVDPLIPLPGFVLKRAIKGAMETATDGLRK
MLBr_00889|M.leprae_Br4923 LEGSYRLVPKGSTTEVTYELAVDFAIPMIGMLKRKAEHRLIDGALKDLKK
:. * : * * * :: :* *: *:: :: : :: . . *:.
Mflv_0509|M.gilvum_PYR-GCK RVLKIKG----
MAV_2785|M.avium_104 RVTEVKKRAAS
MSMEG_5736|M.smegmatis_MC2_155 QVLKVKKG---
Mvan_5073|M.vanbaalenii_PYR-1 QVLKVIKG---
TH_2031|M.thermoresistible__bu RVEQLYGR---
Mb0877|M.bovis_AF2122/97 QVLKVKKGQ--
Rv0854|M.tuberculosis_H37Rv QVLKVKKGQ--
MMAR_4682|M.marinum_M QVLKVKKG---
MUL_0301|M.ulcerans_Agy99 QVLKVKKG---
MAB_0831|M.abscessus_ATCC_1997 QVLATYR----
MLBr_00889|M.leprae_Br4923 RVEG-------
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