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ATSVVYGRAMATKDSREVVIEATPEQILDVIADVEATPTWSPQYQKAEILDRYDNGRPKQVRMTVKAAGL TDEQVIEYTWGDNEVSWTLVSATQLKAQDAGYTLTPAGDKTKVKFDIAIDLSVPLPGFIIKRTIKGGVET ATEGLRKQVLKVIKG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5073 | - | - | 100% (156) | cyclase/dehydrase |
| M. vanbaalenii PYR-1 | Mvan_5072 | - | 3e-34 | 46.48% (142) | cyclase/dehydrase |
| M. vanbaalenii PYR-1 | Mvan_5071 | - | 2e-27 | 38.19% (144) | cyclase/dehydrase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0877 | - | 7e-50 | 61.64% (146) | hypothetical protein Mb0877 |
| M. gilvum PYR-GCK | Mflv_1678 | - | 3e-73 | 88.36% (146) | cyclase/dehydrase |
| M. tuberculosis H37Rv | Rv0854 | - | 7e-50 | 61.64% (146) | hypothetical protein Rv0854 |
| M. leprae Br4923 | MLBr_00889 | - | 5e-21 | 30.99% (142) | hypothetical protein MLBr_00889 |
| M. abscessus ATCC 19977 | MAB_0831 | - | 5e-49 | 61.70% (141) | hypothetical protein MAB_0831 |
| M. marinum M | MMAR_4682 | - | 4e-49 | 59.59% (146) | hypothetical protein MMAR_4682 |
| M. avium 104 | MAV_0975 | - | 4e-50 | 61.64% (146) | cyclase/dehydrase superfamily protein |
| M. smegmatis MC2 155 | MSMEG_5736 | - | 2e-66 | 80.82% (146) | cyclase/dehydrase |
| M. thermoresistible (build 8) | TH_2031 | - | 6e-52 | 65.00% (140) | cyclase/dehydrase |
| M. ulcerans Agy99 | MUL_0301 | - | 6e-49 | 58.90% (146) | hypothetical protein MUL_0301 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5073|M.vanbaalenii_PYR-1 MATSVVYGRAMATKDSREVVIEATPEQILDVIADVEATPTWSPQYQKAEI
Mflv_1678|M.gilvum_PYR-GCK ----------MATKDSREVVIEATPEQILDVIADVEATPTWSPQYQKAEV
MSMEG_5736|M.smegmatis_MC2_155 ----------MATSDSREVLIEASPEEILDVIADVESTPSWSPQYTHAEI
TH_2031|M.thermoresistible__bu ----------MAVSDSRDVVIDATPAQILDVIADVAAVPEWSPQYLSAEV
Mb0877|M.bovis_AF2122/97 ----------MAIKESRDIVIEASPEEILDVIADFEAMTEWSPAHQSVEI
Rv0854|M.tuberculosis_H37Rv ----------MAIKESRDIVIEASPEEILDVIADFEAMTEWSPAHQSVEI
MMAR_4682|M.marinum_M ----------MAIKETRDIVIEASPQEILDVIADFEAMPGWSSPHQSAEI
MUL_0301|M.ulcerans_Agy99 ----------MAIKETRDIVIEASPQEILDVIADFEAMPEWSSPHQSAEI
MAV_0975|M.avium_104 ----------MALKESRDIVIEASPEEILDVIADFESMPQWSEPHQSAEV
MAB_0831|M.abscessus_ATCC_1997 ----------MATSDTREIVIEATPEQIMDVIADFEVLPKWSSAHQSSTV
MLBr_00889|M.leprae_Br4923 ----------MADKTTQTFYIDANPGEVMKTIADIESYPQWISEYKEVEV
** . :: . *:*.* :::..***. . * : :
Mvan_5073|M.vanbaalenii_PYR-1 LDRYDNGRPKQVRMTVKAAGLTDEQVIEYTWGDN--EVSWTLVSATQLKA
Mflv_1678|M.gilvum_PYR-GCK LERFDNGRPKQVKMTVKAAGLTDEQVIEYTWGDD--RVTWTLVSASQLKA
MSMEG_5736|M.smegmatis_MC2_155 TERYDDGRPRRAKMTVKAAGLTDDQVIEYTWSEN--KVSWTLVSAGQLKA
TH_2031|M.thermoresistible__bu LDAHPDGRPRRVKMKVKAAGLTDEQIVDYTWTDH--SAAWTLVSAGQLRS
Mb0877|M.bovis_AF2122/97 LETGDDGRPSKVKMKVKTAGITDEQVVAYSWTDR--SVRWTLVSSTQQRS
Rv0854|M.tuberculosis_H37Rv LETGDDGRPSKVKMKVKTAGITDEQVVAYSWTDR--SVRWTLVSSTQQRS
MMAR_4682|M.marinum_M LETGADGRPSQVKMKVKTAGITDEQVVAYSWGDN--KVNWSLVSSGQQRS
MUL_0301|M.ulcerans_Agy99 FETGADGRPSQVKMKVKTAGITDEQVVAYSWGDN--KVNWSLVSSGQQRS
MAV_0975|M.avium_104 LATGDDGRPSQVRMKVKVAGITDEQVVAYTWADN--VVSWTLVSSSQQKA
MAB_0831|M.abscessus_ATCC_1997 LTTGEDGRPHQVTMKVKTAGITDEQTVAYTWGPD--TVSWTLVKASQQRR
MLBr_00889|M.leprae_Br4923 LEVDDEDFPKRARMLMDAKIFKDTLIMSYDWTADHQSVSWILESSSLLKS
:. * :. * :.. :.* : * * . * * .: :
Mvan_5073|M.vanbaalenii_PYR-1 QDAGYTLTPAGDKTKVKFDIAIDLSVPLPGFIIKRTIKGGVETATEGLRK
Mflv_1678|M.gilvum_PYR-GCK QDAGYTLTPEGDKTRVRFDIAIDLSVPLPGFLLKRTMKGGVETATEGLKK
MSMEG_5736|M.smegmatis_MC2_155 QDASYTLTPQGDKTKVRFDISIDLSVPLPGFIVKRTMKGGVETATDGLRK
TH_2031|M.thermoresistible__bu QDAKYTLRPDGTRTKVTFEITVDPSVPLPGFVLKRAMRGAMETATDGLRK
Mb0877|M.bovis_AF2122/97 QDGKYELTPKGDNTLVQFEITVDPQVPLPGFVLKRAIKGTIDTATEALRS
Rv0854|M.tuberculosis_H37Rv QDGKYELTPKGDNTLVQFEITVDPQVPLPGFVLKRAIKGTIDTATEALRS
MMAR_4682|M.marinum_M QEGSYLLTPEGDKTRVKLELAVDAVVPLPGFVLKRAVKGTVESGLDELRK
MUL_0301|M.ulcerans_Agy99 QEGSYLLTPEGDKTRVKLELAVDAVVPLPGFVLKRAVKGTVESGLDELRK
MAV_0975|M.avium_104 QDGKYTLVPQGDATLVKFELVADPNVPLPGFVLKRAVKGTIDSATKALRQ
MAB_0831|M.abscessus_ATCC_1997 QDGKYTFTPQGDKTHVKFELTVDPLIPLPGFVLKRAIKGAMETATDGLRK
MLBr_00889|M.leprae_Br4923 LEGSYRLVPKGSTTEVTYELAVDFAIPMIGMLKRKAEHRLIDGALKDLKK
:. * : * * * * :: * :*: *:: ::: : :: . . *:.
Mvan_5073|M.vanbaalenii_PYR-1 QVLKVIKG-
Mflv_1678|M.gilvum_PYR-GCK QVHKVLKG-
MSMEG_5736|M.smegmatis_MC2_155 QVLKVKKG-
TH_2031|M.thermoresistible__bu RVEQLYGR-
Mb0877|M.bovis_AF2122/97 QVLKVKKGQ
Rv0854|M.tuberculosis_H37Rv QVLKVKKGQ
MMAR_4682|M.marinum_M QVLKVKKG-
MUL_0301|M.ulcerans_Agy99 QVLKVKKG-
MAV_0975|M.avium_104 RVLEVKKGK
MAB_0831|M.abscessus_ATCC_1997 QVLATYR--
MLBr_00889|M.leprae_Br4923 RVEG-----
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