For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_1679 (-)

annotation: cyclase/dehydrase
coordinates: 1745158 - 1745598
length: 146

MAVRASSELVIEAPPEAIMDALADIESVVSWSSLHKDAEIVDRHPDGRPHHVRATVKIMGLSDQEMLEYH
WGDDWVVWDAEQTSRQRCQHGEYNLTPVGEERTRVRFDLILDLAAPYPTFLVRRAKQMVLDIALQNLRQR
VLAATQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1679--100% (146)cyclase/dehydrase
M. gilvum PYR-GCKMflv_1678-3e-3243.26% (141) cyclase/dehydrase
M. gilvum PYR-GCKMflv_0509-1e-3045.07% (142) cyclase/dehydrase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0880-2e-4554.93% (142) hypothetical protein Mb0880
M. tuberculosis H37RvRv0857-2e-4554.93% (142) hypothetical protein Rv0857
M. leprae Br4923MLBr_00889-2e-1530.77% (143) hypothetical protein MLBr_00889
M. abscessus ATCC 19977MAB_0831-2e-2941.96% (143) hypothetical protein MAB_0831
M. marinum MMMAR_4679-3e-4755.63% (142) hypothetical protein MMAR_4679
M. avium 104MAV_0978-1e-5057.75% (142) hypothetical protein MAV_0978
M. smegmatis MC2 155MSMEG_5736-3e-3042.25% (142) cyclase/dehydrase
M. thermoresistible (build 8)TH_3096-2e-5766.67% (141) PUTATIVE cyclase/dehydrase
M. ulcerans Agy99MUL_0299-2e-4554.61% (141) hypothetical protein MUL_0299
M. vanbaalenii PYR-1Mvan_5072-5e-7386.30% (146) cyclase/dehydrase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1679|M.gilvum_PYR-GCK          -------MAVRASSELVIEAPPEAIMDALADIESVVSWSSLHKDAEIVDR
Mvan_5072|M.vanbaalenii_PYR-1       -------MAVRASSEVVIEAPPEAILDALADIEAVASWSSLHKDAEVVDR
TH_3096|M.thermoresistible__bu      -------MAVRASREVVIDAPVEAILDVLADIDQVPSWSTLHRRAEVLDR
Mb0880|M.bovis_AF2122/97            MIANLVAVAIRASREVVIEAPPEVIVEALADMDAVPSWSSVHKRVEVVDT
Rv0857|M.tuberculosis_H37Rv         MIANLVAVAIRASREVVIEAPPEVIVEALADMDAVPSWSSVHKRVEVVDT
MMAR_4679|M.marinum_M               MVASLVAVAIQASGEIVIDAPPEVIMEALADMGAVPSWSVVHKRVEVVDN
MAV_0978|M.avium_104                -------MAVQASSEIVIDAPPEVIMEALADMDAVPSWSSVHKRVEVIDK
MUL_0299|M.ulcerans_Agy99           -------MAVKAAREFVIDAPPEVVMEALTDVGVLVSWSPLHKSVEVIDY
MAB_0831|M.abscessus_ATCC_1997      -------MATSDTREIVIEATPEQIMDVIADFEVLPKWSSAHQSSTVLTT
MSMEG_5736|M.smegmatis_MC2_155      -------MATSDSREVLIEASPEEILDVIADVESTPSWSPQYTHAEITER
MLBr_00889|M.leprae_Br4923          -------MADKTTQTFYIDANPGEVMKTIADIESYPQWISEYKEVEVLEV
                                           :*   :  . *:*    ::..::*.    .*   :    :   

Mflv_1679|M.gilvum_PYR-GCK          HPDGRPHHVRATVKIMGLSDQEMLEYHWGDDW--VVWDAEQTSRQRCQHG
Mvan_5072|M.vanbaalenii_PYR-1       YPDGRPHHVKATVKIMGLTDKEFLEYHWGDDW--VVWDAERTSRQRCQHG
TH_3096|M.thermoresistible__bu      HPDGRPHHVRATLRILGVTDRQILEYHWGPSW--MVWDAEETFQQRGQHG
Mb0880|M.bovis_AF2122/97            YSDGRPHHVKVTIKVAGIVDTELLEYHWGPDW--VVWDAAKTAQQHGQHG
Rv0857|M.tuberculosis_H37Rv         YSDGRPHHVKVTIKVAGIVDTELLEYHWGPDW--VVWDAAKTAQQHGQHG
MMAR_4679|M.marinum_M               YPDGRPHHVRVTIKVTGIADTELLEYHWGPDW--MVWDAQRTVQQHGQHG
MAV_0978|M.avium_104                HPDGRPHHVRVTIAVVGIHDTELLEYHWGPDW--MVWDADRTAQQHGQHG
MUL_0299|M.ulcerans_Agy99           YPDGRPHHVKATIKILGLVDKEILEYHWGPDW--VCWDADQTFQQRGQHV
MAB_0831|M.abscessus_ATCC_1997      GEDGRPHQVTMKVKTAGITDEQTVAYTWGPDT--VSWTLVKASQQRRQDG
MSMEG_5736|M.smegmatis_MC2_155      YDDGRPRRAKMTVKAAGLTDDQVIEYTWSENK--VSWTLVSAGQLKAQDA
MLBr_00889|M.leprae_Br4923          DDEDFPKRARMLMDAKIFKDTLIMSYDWTADHQSVSWILESSSLLKSLEG
                                      :. *::.   :    . *   : * *  .   : *    :   :  . 

Mflv_1679|M.gilvum_PYR-GCK          EYNLTPVGEERTRVRFDLILDLAAPYPTFLVRRAKQMVLDIALQNLRQRV
Mvan_5072|M.vanbaalenii_PYR-1       EYNLTSVGEQRTRVRFDLLLDLAAPYPGFLVKRAKKMVLDIALQNLRQRV
TH_3096|M.thermoresistible__bu      EYNLTPVGQDRTRVRFDLIMELAAPVPHFLIKRGRRIVLDVATEKLKERV
Mb0880|M.bovis_AF2122/97            EYNLRREDNDKTRVRFTLTVEPSAPLPAFWVNIARKKILHAATEGLRKQV
Rv0857|M.tuberculosis_H37Rv         EYNLRREDNDKTRVRFTLTVEPSAPLPAFWVNIARKKILHAATEGLRKQV
MMAR_4679|M.marinum_M               EYNLRREADNKTRVRFSITVEPSAPLPEFWVNRARRKILHSALEGLRKRV
MAV_0978|M.avium_104                EYNLSRLGDDKTRVRFTITVEPWVPLPEFWVRRARKKILHAALEGLRKRV
MUL_0299|M.ulcerans_Agy99           EYTVRPEGLDKSRVRFDITVEPSGPISGFIVKRASEHVLDAAAKGLSELV
MAB_0831|M.abscessus_ATCC_1997      KYTFTPQG-DKTHVKFELTVDPLIPLPGFVLKRAIKGAMETATDGLRKQV
MSMEG_5736|M.smegmatis_MC2_155      SYTLTPQG-DKTKVRFDISIDLSVPLPGFIVKRTMKGGVETATDGLRKQV
MLBr_00889|M.leprae_Br4923          SYRLVPKG-STTEVTYELAVDFAIPMIGMLKRKAEHRLIDGALKDLKKRV
                                    .* .     . :.* : : ::   *   :  .   .  :. * . * : *

Mflv_1679|M.gilvum_PYR-GCK          LAATQ-------
Mvan_5072|M.vanbaalenii_PYR-1       LAGAE-------
TH_3096|M.thermoresistible__bu      YRCLGSSAPKRT
Mb0880|M.bovis_AF2122/97            VGRRRFTSG---
Rv0857|M.tuberculosis_H37Rv         VGRRRFTSG---
MMAR_4679|M.marinum_M               MGPAD-------
MAV_0978|M.avium_104                MVPEAFGRAD--
MUL_0299|M.ulcerans_Agy99           ANRDATDQAK--
MAB_0831|M.abscessus_ATCC_1997      LATYR-------
MSMEG_5736|M.smegmatis_MC2_155      LKVKKG------
MLBr_00889|M.leprae_Br4923          EG----------