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MTSPVPTDKKTVIVIAFDGSPTARRAVAYAARFLTADRAVVLTAWTPLNRGTDPQDYDYDLDGPPDPRDE ELDIALAEAQRINDEGVELAVAAGLPAEPMRRAVTFTVWQAIIEAADELDADLIVTGTRATTGFRSLIQS SVADHVLRRGHRPVLIVPPEP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0416 | - | - | 100% (161) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_5002 | - | 6e-09 | 33.10% (145) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_3551 | - | 2e-06 | 29.14% (151) | UspA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1662 | TB15.3 | 2e-06 | 30.00% (150) | hypothetical protein Mb1662 |
| M. tuberculosis H37Rv | Rv1636 | TB15.3 | 2e-06 | 30.00% (150) | hypothetical protein Rv1636 |
| M. leprae Br4923 | MLBr_01390 | - | 3e-05 | 26.00% (150) | hypothetical protein MLBr_01390 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0859 | - | 1e-12 | 33.77% (151) | universal stress protein UspA |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0449 | - | 1e-14 | 35.37% (147) | transporter, major facilitator family protein, putative |
| M. thermoresistible (build 8) | TH_3159 | - | 2e-50 | 67.11% (149) | PUTATIVE UspA domain protein |
| M. ulcerans Agy99 | MUL_0611 | - | 8e-13 | 33.77% (151) | hypothetical protein MUL_0611 |
| M. vanbaalenii PYR-1 | Mvan_0255 | - | 3e-76 | 85.80% (162) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0416|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0255|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3159|M.thermoresistible__bu --------------------------------------------------
Mb1662|M.bovis_AF2122/97 --------------------------------------------------
Rv1636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
MMAR_0859|M.marinum_M --------------------------------------------------
MUL_0611|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0449|M.smegmatis_MC2_155 MRQGPLAGRYPAVATMVTLALIPYLALSAAIDPLVPIICEQLHMTPQEMS
Mflv_0416|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0255|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3159|M.thermoresistible__bu --------------------------------------------------
Mb1662|M.bovis_AF2122/97 --------------------------------------------------
Rv1636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
MMAR_0859|M.marinum_M --------------------------------------------------
MUL_0611|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0449|M.smegmatis_MC2_155 LGSGLGNAAYAVGTVLAVQFAQHLPQRRMMIAYAVLLVIGSAVAASAPNG
Mflv_0416|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0255|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3159|M.thermoresistible__bu --------------------------------------------------
Mb1662|M.bovis_AF2122/97 --------------------------------------------------
Rv1636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
MMAR_0859|M.marinum_M --------------------------------------------------
MUL_0611|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0449|M.smegmatis_MC2_155 TVFIIGHVLQGLSTSMLLIAAAPPLTIGFPREKLRHTAVIMNMCVFGAVA
Mflv_0416|M.gilvum_PYR-GCK --------------------MTSPVPTDKKTVIVIAFDGSP----TARRA
Mvan_0255|M.vanbaalenii_PYR-1 --------------------MTGPEPRDKKSVLVIAFDGSP----TARRA
TH_3159|M.thermoresistible__bu --------------------------------MVIAYDGSR----NARRA
Mb1662|M.bovis_AF2122/97 --------------------------MSAYKTVVVGTDGSD----SSMRA
Rv1636|M.tuberculosis_H37Rv --------------------------MSAYKTVVVGTDGSD----SSMRA
MLBr_01390|M.leprae_Br4923 --------------------------MGAYQTVVVGTDGSD----SSLRA
MMAR_0859|M.marinum_M ----------------------------MPVNAVVGYDGSP----GASTA
MUL_0611|M.ulcerans_Agy99 --------------MAGLVARDLSRRCTVPVNAVVGYDGSP----GASTA
MSMEG_0449|M.smegmatis_MC2_155 LGPFVGGTQAEAHAWRPLFWIIAAIALAALVMALLTFEDAPPADRTAPRD
:: :.: :
Mflv_0416|M.gilvum_PYR-GCK VAYAARFLTADRAVVLTAWTPLNRGTDPQDYDYDLDG-----PPDPRDE-
Mvan_0255|M.vanbaalenii_PYR-1 VQYAGRFLTADRAVVLTVWSPLDRGSDPGSYSYDLDG-----PPDPRDDD
TH_3159|M.thermoresistible__bu VQYAGHFFAGRRAVVLTVWTPLERGPEP--VQVDLDG-----PPDPPEP-
Mb1662|M.bovis_AF2122/97 VDRAAQIAGAD-AKLIIASAYLPQHEDARAADILKDE-----SYKVTGT-
Rv1636|M.tuberculosis_H37Rv VDRAAQIAGAD-AKLIIASAYLPQHEDARAADILKDE-----SYKVTGT-
MLBr_01390|M.leprae_Br4923 VDRAGKIAGSD-AKLIIASAYLPQHDNARAFDILKDE-----SYKVTGT-
MMAR_0859|M.marinum_M IEAGALLFPGARGWITYLWVPPFASEKVRRRLRPMAS-----NTNELVEM
MUL_0611|M.ulcerans_Agy99 IEAGALLFPGARGWITYLWVPPFASEKVRRRLRPMAS-----NTNELVEM
MSMEG_0449|M.smegmatis_MC2_155 IKAIALAAVGCAAAFIGAAQLTSHGFDDAAVTVPMLGGLLLIVTLIVYQF
: . . . . .
Mflv_0416|M.gilvum_PYR-GCK ELDIALAEAQRINDEGVELA-VAAGLPAEPMRRAVTFTVWQAIIEAADEL
Mvan_0255|M.vanbaalenii_PYR-1 EIDIALAEAQRINDEGLELA-LAAGLPAEPLRRAATFTVWQAIIEAADEL
TH_3159|M.thermoresistible__bu DEDIKLASARRVNNEGVELA-RTAGLAAEPLCMPESGTVWNTIIETADEL
Mb1662|M.bovis_AF2122/97 ------APIYEILHDAKERA-HNAG-AKNVEERPIVGAPVDALVNLADEE
Rv1636|M.tuberculosis_H37Rv ------APIYEILHDAKERA-HNAG-AKNVEERPIVGAPVDALVNLADEE
MLBr_01390|M.leprae_Br4923 ------APIYEILHDAKERA-HAAG-AKNVEERPVVGAPVDALVNLAEKT
MMAR_0859|M.marinum_M VEREGELEARRVVAMGATLA-RAAGWDAEPVLKRTWGPEGLRMAEEADEV
MUL_0611|M.ulcerans_Agy99 VEREGELEARRVVAMGATLA-RAAGWDAEPVLKRTWGPEGLRMAEEADEV
MSMEG_0449|M.smegmatis_MC2_155 RAPRPLLTIRTMLTSSIPVAGVGVALFAAAASVAATALTAEVFLESFNPV
: . * .. : : :
Mflv_0416|M.gilvum_PYR-GCK DADLIVTGTRA----------------------TTGFRSLIQSSVADHVL
Mvan_0255|M.vanbaalenii_PYR-1 DADLIVTGTRA----------------------TTGLRSLIQSSVADHVL
TH_3159|M.thermoresistible__bu DADLIVTGTRG----------------------TTGLRSLLQSSVADNVL
Mb1662|M.bovis_AF2122/97 KADLLVVGNVG----------------------LSTIAGRLLGSVPANVS
Rv1636|M.tuberculosis_H37Rv KADLLVVGNVG----------------------LSTIAGRLLGSVPANVS
MLBr_01390|M.leprae_Br4923 NADLLVVGNVG----------------------LSTIAGRLLGSVPANVS
MMAR_0859|M.marinum_M QADLVLVGTRG----------------------LGGTQAVLG-SVADMVL
MUL_0611|M.ulcerans_Agy99 QADLVLVGTRG----------------------LGGTQAVLG-SVADMVL
MSMEG_0449|M.smegmatis_MC2_155 HVGLLYLPELGGAVVMAFVFGHVISRRAMHYLPLVGMALLAAGVVAFRFA
...*: . *. .
Mflv_0416|M.gilvum_PYR-GCK RRGHRPVLIVPPEP------------------------------------
Mvan_0255|M.vanbaalenii_PYR-1 RRGGRPVLIVPPEP------------------------------------
TH_3159|M.thermoresistible__bu RRGRRPVLIVPPGPR-----------------------------------
Mb1662|M.bovis_AF2122/97 RRAKVDVLIVHTT-------------------------------------
Rv1636|M.tuberculosis_H37Rv RRAKVDVLIVHTT-------------------------------------
MLBr_01390|M.leprae_Br4923 RRAKIDVLIVHTTH------------------------------------
MMAR_0859|M.marinum_M HRCPRPVVVVPNPMLAAEYDALPKGPMVVG--------WDGSAGSETALA
MUL_0611|M.ulcerans_Agy99 HRCPRPVVVVPNPMLAAEYDALPKGPMVVG--------WDGSAGSETALA
MSMEG_0449|M.smegmatis_MC2_155 LPANQPLALVGSALTGLALGATVAPALFVAGFSLQSNSLQRVFAIIELLR
: :*
Mflv_0416|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0255|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3159|M.thermoresistible__bu --------------------------------------------------
Mb1662|M.bovis_AF2122/97 --------------------------------------------------
Rv1636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
MMAR_0859|M.marinum_M AARRLCPDREVVLVFVGDGSVPPPAAGVGELRQLSVERGRGFHARAVSEA
MUL_0611|M.ulcerans_Agy99 AARRLCPDREVVLVFVGDGSAPPPAAGVGELRQLSVERGRGFHARAVSEA
MSMEG_0449|M.smegmatis_MC2_155 AVAAFMVAPIFAHFALTATGGLVQGTGDALWISLGLAIGGALFGVVVYLL
Mflv_0416|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0255|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3159|M.thermoresistible__bu --------------------------------------------------
Mb1662|M.bovis_AF2122/97 --------------------------------------------------
Rv1636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
MMAR_0859|M.marinum_M LVAAGQDNGAALLVVGSRGHSGARETLLGSVAMGTVHHSHRPVL------
MUL_0611|M.ulcerans_Agy99 LVAAGQDNGAALLVVGSRGHSGARETLRARDIAWQRRNGHRAPLPSAGPG
MSMEG_0449|M.smegmatis_MC2_155 SGARPQAPDIDRFLDGDDPAWYSPPLLARLRPGLPAPQVPAAVTPSRPAA
Mflv_0416|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0255|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3159|M.thermoresistible__bu --------------------------------------------------
Mb1662|M.bovis_AF2122/97 --------------------------------------------------
Rv1636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
MMAR_0859|M.marinum_M ----VVPSGWQVPADS----------------------------------
MUL_0611|M.ulcerans_Agy99 GAERVAGSRRLLSADGALGPRSARWVTSGSDPAGV---------------
MSMEG_0449|M.smegmatis_MC2_155 RVVPALTGPVLIAYDGSERAANAIDFAAGRLSGERDALVVCVWQPADVGF
Mflv_0416|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0255|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3159|M.thermoresistible__bu --------------------------------------------------
Mb1662|M.bovis_AF2122/97 --------------------------------------------------
Rv1636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
MMAR_0859|M.marinum_M --------------------------------------------------
MUL_0611|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0449|M.smegmatis_MC2_155 TPAGTEPFDADQASEVRRAAERTAARGAELAEAAGFTACSVAVEAAPTWQ
Mflv_0416|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0255|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3159|M.thermoresistible__bu --------------------------------------------------
Mb1662|M.bovis_AF2122/97 --------------------------------------------------
Rv1636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
MMAR_0859|M.marinum_M --------------------------------------------------
MUL_0611|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0449|M.smegmatis_MC2_155 GIVETAEKHGASMIVIGPHRRSGFLGHLQGSVAAAVVAHATTPVLVVPEA
Mflv_0416|M.gilvum_PYR-GCK ----------------
Mvan_0255|M.vanbaalenii_PYR-1 ----------------
TH_3159|M.thermoresistible__bu ----------------
Mb1662|M.bovis_AF2122/97 ----------------
Rv1636|M.tuberculosis_H37Rv ----------------
MLBr_01390|M.leprae_Br4923 ----------------
MMAR_0859|M.marinum_M ----------------
MUL_0611|M.ulcerans_Agy99 ----------------
MSMEG_0449|M.smegmatis_MC2_155 TPKLTPELLRSVAVPH