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AHRRARLLLSASAAAAISGLLLIAAPAVSAEPDGGGTETTVRSSAKPADGDDRAAEADDASGPERTDRKA GSDTDEAPRKPRKPQGDRMILDSPDAEAAEDPETPEEAADTERALTETTQIDPLPEAPPETSTVVPAERS ESTPTDPVPDTDIDTTAPGAAIVPIATVEATEANRASEAGDRRPTLLNVVGSLVLNLLVGFIQVIDGPPV LPPNSTVTVRTSSLTLPIGGGRSVQADWYFPEEYSSGQLDSATRLVYLQHGFLASGPLYSYTAARLAERT GAIVVAPSLTSNFFAADAAWVGGSTMHRAVADLFAGDRPALTQSASAAAGYVVRLPEKFVLVGHSAGGSL VTSAAGFMADNGAIDALTGIVMLDGVEPAGSRLVGSALAKLRGSSDRPVYLISSERYFWSRGGDMADKLQ LARPGRFNGVGLQGGLHIDYMEGGNPLVQFGEYVVAGFSLRRNVDAASEITIGWVDDLFAGTAAGVYGSP GDVVAVVTPSGTATAVVLPLGEPARPVWPPLLDAALTAVFDFAGRHLFVYEPLRGYDLQPTG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0365 | - | - | 100% (553) | hypothetical protein Mflv_0365 |
| M. gilvum PYR-GCK | Mflv_5098 | - | 7e-89 | 39.47% (527) | hypothetical protein Mflv_5098 |
| M. gilvum PYR-GCK | Mflv_2002 | - | 8e-56 | 36.71% (425) | hypothetical protein Mflv_2002 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0869c | - | 2e-06 | 24.89% (225) | resuscitation-promoting factor RpfA |
| M. marinum M | MMAR_3402 | - | 5e-44 | 32.55% (427) | PE-PGRS family protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5412 | - | 4e-05 | 29.52% (166) | immunogenic protein MPT63 |
| M. thermoresistible (build 8) | TH_3241 | - | 1e-07 | 24.59% (183) | PUTATIVE putative FHA domain containing protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0370 | - | 1e-179 | 60.49% (567) | hypothetical protein Mvan_0370 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0365|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0370|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3402|M.marinum_M --------------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 --------------------------------------------------
TH_3241|M.thermoresistible__bu VGAPPRSKEVMVNVTLGVFVESGTARIVLVDADPPNPVVDQTDLDLAAAD
Mflv_0365|M.gilvum_PYR-GCK -------------------------------MAHRRARLLLSASAAAAIS
Mvan_0370|M.vanbaalenii_PYR-1 -------------------------------MDSRWTVLIGAGFVAATMS
MMAR_3402|M.marinum_M ------------------------------------------------MS
MAB_0869c|M.abscessus_ATCC_199 ------------------------------------------------MS
MSMEG_5412|M.smegmatis_MC2_155 ------------------------------------------------MN
TH_3241|M.thermoresistible__bu STPDTLVTTVLATAGALTESGHRLVGISLCGPAADRIGPVHDALTGSGLR
:
Mflv_0365|M.gilvum_PYR-GCK GLLLIAAPAVSAEP--------------DGGGTETTVRSSAKPADGDDRA
Mvan_0370|M.vanbaalenii_PYR-1 GLVVLGVPTAFAAPG----------ETETVSATESDTPSDAAPAETSAPD
MMAR_3402|M.marinum_M TYVIAAPDAFSVASG----------ELAGIEAAVKGAAAAAAPSTTGIIS
MAB_0869c|M.abscessus_ATCC_199 GRHSKPSKASAKAAK----------VAVAGAGLVGGGLMMAATAN-----
MSMEG_5412|M.smegmatis_MC2_155 ALKITNLSTAVAAA-----------------AVAAAAILGTAPAAFGDAS
TH_3241|M.thermoresistible__bu PVTVVDESDAVTAVVRTLAGDETVATLVNDGATVALSMTEAGGVTTPVAT
. :
Mflv_0365|M.gilvum_PYR-GCK AEADD-ASGPER------TDRKAGSDTDEAPRKP-RKPQGDRMILDS---
Mvan_0370|M.vanbaalenii_PYR-1 TEHEDEQSAPEHGIDAANPPLEADLEADLEAEYPDRERNGDKVIPVEGDV
MMAR_3402|M.marinum_M AAADEVSTAIAR----------------------LFGSYADEFQTLSAQA
MAB_0869c|M.abscessus_ATCC_199 AATDGEWDQVAR-----------------------CESGGNWAINTG---
MSMEG_5412|M.smegmatis_MC2_155 AVTTSTLGSAAK--------------------------------------
TH_3241|M.thermoresistible__bu EPIDGDPQAAYRTLVERFAADPGAASGLIVMGSLGDGGLPADLVETSPVP
:
Mflv_0365|M.gilvum_PYR-GCK PDAEAAEDPETPEEAADTERALT-ETTQIDPLPEAPPETSTVVPAERSES
Mvan_0370|M.vanbaalenii_PYR-1 TDGAVGDEGAVGDEGVVGEDVVGDEDVDVDEDIAEPAEPAVIVESDAGIT
MMAR_3402|M.marinum_M TRFQAQFERALSEAGAAYAAAEAANVSPLRALLQEAESLGVFAPIERLIG
MAB_0869c|M.abscessus_ATCC_199 ----NGYQGGLQFSPSTWINSGGGQYAPSAHLATKEQQIAVAEKVLAGQG
MSMEG_5412|M.smegmatis_MC2_155 -----LNNGDVVQAWTVTDLKPSSDTIPYEVRGKLWEVTATDEAVQGNVT
TH_3241|M.thermoresistible__bu LRFPDDPEFMLARGATLASLSQDATMAAPVVADELPTTVTPLETADTMQS
:
Mflv_0365|M.gilvum_PYR-GCK TPTDPVPDTDID------TTAPGAAIVPIATVEATEANRASEAG-DRRPT
Mvan_0370|M.vanbaalenii_PYR-1 PAT--VTFTEEP------RTDKDSPQRSLAETESVPLGATAETTPSRAPS
MMAR_3402|M.marinum_M RPLFGNGSVAAA------STGATEASSLLTSGTNQAGLGGAVNYAAAEAL
MAB_0869c|M.abscessus_ATCC_199 RGAWPVCGRGLSG-----STPRTAPAANITPAAHHEEQAAAEPAPAPEPP
MSMEG_5412|M.smegmatis_MC2_155 PIVSNFNVRAADG-----TNYRALFQVATPQGVNPSTIPQGEKASGKIYF
TH_3241|M.thermoresistible__bu QQLAYSEVPDEDSDLLGFTDPVDTPGADGPAGGFDPEAEDAEDADAEDAV
. .
Mflv_0365|M.gilvum_PYR-GCK ------------LLNVVGSLVLNLLVGFIQVIDGPPVLPPNSTVTVRTSS
Mvan_0370|M.vanbaalenii_PYR-1 ------------LLNLVGSVVLNVLVGFIQLIDGPPVLPANSSVTVRTST
MMAR_3402|M.marinum_M ------------AAPATGATGVKSGFSFLQIPIGPSEFLG-----ITIPQ
MAB_0869c|M.abscessus_ATCC_199 ------------AEGDEQFVAEAPEAPAIDEAPAPEEAPAP-----EAQD
MSMEG_5412|M.smegmatis_MC2_155 ------------DVTGPEPTTVVYNAGGKDLLVWDKPAAS----------
TH_3241|M.thermoresistible__bu RRRQWLIGSSVGALAAVGFATLAVSVAITIEPTSSQQAVRLQEGPVPGKA
Mflv_0365|M.gilvum_PYR-GCK LTLPIGGGRSVQADWYFPEEYSSGQLDSATRLVYLQHGFLASG--PLYSY
Mvan_0370|M.vanbaalenii_PYR-1 LNLPIGSGRSVQADWYFPET-----VDESTRLVYFQHGFLASG--PMYSY
MMAR_3402|M.marinum_M FNFPAP------AHWYFPTQADG--SVNANGVIYLQHGFGAIG--WFYQP
MAB_0869c|M.abscessus_ATCC_199 VDFQSG-------------------PAPEEPAPAPEPAPVDEA--QAPAP
MSMEG_5412|M.smegmatis_MC2_155 --------------------------ATAPSGTGQSRPATASS--PATAA
TH_3241|M.thermoresistible__bu FPVAPGQGVEPDGPNWTMIEHLPPPGAPAEVRTFETRALSSSRDVSKAAA
Mflv_0365|M.gilvum_PYR-GCK TAARLAERTGAIVVAPSLTSNFFAADAAWVGG------------------
Mvan_0370|M.vanbaalenii_PYR-1 TAARLAERTNAIVVAPSLTSNFFAPDAAWVGG------------------
MMAR_3402|M.marinum_M LAMQLAQQTNSIVVVPTVPS-IPLPFGMWIGG------------------
MAB_0869c|M.abscessus_ATCC_199 ELIAAPAPEAPVVDEAPAPEEAPAPEAPAADD------------------
MSMEG_5412|M.smegmatis_MC2_155 PTAAAEAESEAATDAETEATPAPAAASTAEGG------------------
TH_3241|M.thermoresistible__bu PAIVNVYRDGTVAVQNAAAPLLPVGPAPALPGTVPVTVPGPVFAEWPEYV
. . . . . .
Mflv_0365|M.gilvum_PYR-GCK ------------------------------STMHRAVADLFAGDR-----
Mvan_0370|M.vanbaalenii_PYR-1 ------------------------------STMHRAVAELFVGDR-----
MMAR_3402|M.marinum_M ------------------------------AQMQQGVGSLFLGSQ-----
MAB_0869c|M.abscessus_ATCC_199 ------------------------------QVLP---YELQSGPA-----
MSMEG_5412|M.smegmatis_MC2_155 ------------------------------TEATPAGAGSRATDL-----
TH_3241|M.thermoresistible__bu TRLIPDFSRIRPVDLLYFLANLRELLPPLEATTPDPDDGFDIGDIGVLAV
Mflv_0365|M.gilvum_PYR-GCK ----PALTQSASAAAGYVVRLPEKFVLVGHSAGGSLVTSAAGFMADNG--
Mvan_0370|M.vanbaalenii_PYR-1 ----AALAESAGAAAGHTITLPDKFVLVGHSAGGTLVTSAAGFMVDNG--
MMAR_3402|M.marinum_M ----TALNISANQAG-YLGTLPQDFILSGHSAGGGLASIAAGSYLANLGA
MAB_0869c|M.abscessus_ATCC_199 ----PAEPAPAPEPAPAPAAAPEIPLPAGVPDAADIGFAAGKAAFDAG--
MSMEG_5412|M.smegmatis_MC2_155 ----PAATAAEAETEATATDAETTPVTEETPAAPAPEGTTPVSLG-----
TH_3241|M.thermoresistible__bu VPRDQGVLFSADADAAGPEMIPARLFDPQTPAADKTQLLPPGTTVLDVPT
. . . . . .
Mflv_0365|M.gilvum_PYR-GCK AIDALTGIVMLDGVEPAGSRLVGSALAKLRGSSDRPVYLISSERYFWSRG
Mvan_0370|M.vanbaalenii_PYR-1 AIEHLAGVVMLDGVEPAGSRLVGDALAKLRGAHDRPIYLISSERYFWSRG
MMAR_3402|M.marinum_M ATNHLQGVVMFDGVASN-SSAFGAAVANLQAAN-VPIYVVAAPPQPWNAF
MAB_0869c|M.abscessus_ATCC_199 -------PVASNGIPTSPEAVAG---------------VVRHLPDPNNLP
MSMEG_5412|M.smegmatis_MC2_155 -------TPAAEGTPAVEGAPAGASAGN----------VATAVPPAAPAE
TH_3241|M.thermoresistible__bu DGDGDDPTAALTGEPTTGDTDESRSQRPGMDTEPAG-TPEDSDSDADAGD
* . .
Mflv_0365|M.gilvum_PYR-GCK GDMADKLQLARPGRFNGVGLQGGLHIDYMEGGNPLVQFGEYVVAGFSLRR
Mvan_0370|M.vanbaalenii_PYR-1 GDMADKLQLARPDRFTGVGLKGGLHIDYMEGGNPIVQFGEYLVGGFSLPR
MMAR_3402|M.marinum_M GATTNQLVSLYPGQFTGVEIVNGSHVDSMLGGNPLIDFAAQLLTGFSPPG
MAB_0869c|M.abscessus_ATCC_199 PGTTDVAPGDSRGVSYLKDIVFAMQTQDVKASDAILALAQR---------
MSMEG_5412|M.smegmatis_MC2_155 GAPAEVADP----ALVPAGVQPTTTVPAPAPTTAPVSHGPAA--------
TH_3241|M.thermoresistible__bu GSVVDETGVDETGPAPDSGPDSGPGSEPTEVTHPTPPAEPTVAPDEPTSR
.: .
Mflv_0365|M.gilvum_PYR-GCK NVDAASEITIGWVDDLFAGTAAG--VYGSPGDVVAVVTPSGTATAVVLPL
Mvan_0370|M.vanbaalenii_PYR-1 NIDAAADITVGWVNDLFAGTMTEG-VYGAPGQHIPVVTPSGTATAVVLPL
MMAR_3402|M.marinum_M ATQAVYTLSSGWINDIWAGADPLNPIYGIYGPTGGYVAPGG----QAIFL
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 --------------------------------------------------
TH_3241|M.thermoresistible__bu PSTSAPAPAPDPDTPTQAPAVQAPPASQEPATRAPATQAPATQAPATQAP
Mflv_0365|M.gilvum_PYR-GCK GEPARPVWPPLLDAALTAVFDFAGRHLFVYEPLRGYDLQPTG--------
Mvan_0370|M.vanbaalenii_PYR-1 GVPARPVWPPLLDTILTAVFDFGGRYLFVYEPLRGYQTAANPATSQQGAL
MMAR_3402|M.marinum_M GPTAGIVLPA----------------------------------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5412|M.smegmatis_MC2_155 --------------------------------------------------
TH_3241|M.thermoresistible__bu GTQEPITQAPATEEPATQAPVTQGPATQAPRTVAPQTQAPETVAPQVEAP
Mflv_0365|M.gilvum_PYR-GCK ---------------------
Mvan_0370|M.vanbaalenii_PYR-1 VGASRH---------------
MMAR_3402|M.marinum_M ---------------------
MAB_0869c|M.abscessus_ATCC_199 ---------------------
MSMEG_5412|M.smegmatis_MC2_155 ---------------------
TH_3241|M.thermoresistible__bu VTTMPQYPVGGGSFGGGADGD