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PAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGENFALHLIPSGILTPGVTNVIGN GVVVDPGVLLTELKGLEDRGVDTDRLLISADAHLLMPYHVAIDKVVERYAGSKKIGTTGRGIGPCYQDKI ARQGIRVADVLDPAVLAEKIEGALELKNQVLVKIYNRKALEPAEVVENLLEQAEGFKHRIADARLLLNEA LERDEIVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGASVGSGIGPTRITTVLGILKAYTTRVGSGPFPTE LFDEHGAYLAKTGGEVGVTTGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPICVGYTVDG KRTDEMPMTQSDIARAEPVYEELPGWWEDISGAREFDDLPAKARDYVLRLEELAGAHVSCIGVGPGRDQT IVRRDILATS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0228 | - | - | 100% (431) | adenylosuccinate synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0364c | purA | 0.0 | 88.08% (428) | adenylosuccinate synthetase |
M. tuberculosis H37Rv | Rv0357c | purA | 0.0 | 88.08% (428) | adenylosuccinate synthetase |
M. leprae Br4923 | MLBr_00280 | purA | 0.0 | 86.68% (428) | adenylosuccinate synthetase |
M. abscessus ATCC 19977 | MAB_4249c | - | 0.0 | 89.33% (431) | adenylosuccinate synthetase |
M. marinum M | MMAR_0680 | purA | 0.0 | 89.95% (428) | adenylosuccinate synthetase PurA |
M. avium 104 | MAV_4777 | purA | 0.0 | 89.74% (429) | adenylosuccinate synthetase |
M. smegmatis MC2 155 | MSMEG_0759 | purA | 0.0 | 95.57% (429) | adenylosuccinate synthetase |
M. thermoresistible (build 8) | TH_0134 | purA | 0.0 | 91.10% (427) | PROBABLE ADENYLOSUCCINATE SYNTHETASE PURA (IMP--ASPARTATE |
M. ulcerans Agy99 | MUL_2834 | purA | 0.0 | 89.25% (428) | adenylosuccinate synthetase |
M. vanbaalenii PYR-1 | Mvan_0677 | - | 0.0 | 96.04% (429) | adenylosuccinate synthetase |
CLUSTAL 2.0.9 multiple sequence alignment MLBr_00280|M.leprae_Br4923 MPAVVLIGAQWGDEGKGKVTDLLGGRAQWVVRYQGGNNAGHTVVLPTGEN MAV_4777|M.avium_104 MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGEN Mb0364c|M.bovis_AF2122/97 MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGEN Rv0357c|M.tuberculosis_H37Rv MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGEN MMAR_0680|M.marinum_M MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPSGEN MUL_2834|M.ulcerans_Agy99 MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPSGEN Mflv_0228|M.gilvum_PYR-GCK MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGEN Mvan_0677|M.vanbaalenii_PYR-1 MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGEN MSMEG_0759|M.smegmatis_MC2_155 MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGEN TH_0134|M.thermoresistible__bu ----VLIGAQWGDEGKGKATDLLGGRVRWVVRYQGGNNAGHTVVLPTGEN MAB_4249c|M.abscessus_ATCC_199 MPAIVLIGAQWGDEGKGKATDLLGGSVQWVVRYQGGNNAGHTVVLPNGEN **************.****** .:******************.*** MLBr_00280|M.leprae_Br4923 FTLHLIPSGVLTPGVTNVIGNGVVVDPGVLLSELQGLEDRGVDTSQLLIS MAV_4777|M.avium_104 FALHLIPSGVLTPGVTNVIGNGVVVDPGVLLDELKGLEDRGVDTSRLLIS Mb0364c|M.bovis_AF2122/97 FALHLIPSGVLTPGVTNVIGNGVVIDPGVLLNELRGLQDRGVDTAKLLIS Rv0357c|M.tuberculosis_H37Rv FALHLIPSGVLTPGVTNVIGNGVVIDPGVLLNELRGLQDRGVDTAKLLIS MMAR_0680|M.marinum_M FALHLIPSGVLTPGVTNVIGNGVVIDPGVLLSELKGLEDRGVDTSKLLIS MUL_2834|M.ulcerans_Agy99 FALHLIPSGVLTPGVTNVIGNGVVIDPGVLLSELKGLEDRGVDTAKLLIS Mflv_0228|M.gilvum_PYR-GCK FALHLIPSGILTPGVTNVIGNGVVVDPGVLLTELKGLEDRGVDTDRLLIS Mvan_0677|M.vanbaalenii_PYR-1 FALHLIPSGILTPGVTNVIGNGVVVDPGVLLAELKGLEERGVDTERLLIS MSMEG_0759|M.smegmatis_MC2_155 FALHLIPSGILTPGVTNVIGNGVVVDPGVLLTELKGLEDRGVDTSNLLIS TH_0134|M.thermoresistible__bu FALHLIPSGILTPGVTNVIGNGVVVDPGVLLTELHGLEERGVDTERLLIS MAB_4249c|M.abscessus_ATCC_199 FALHLIPSGILTPGVTNVIGNGVVVDPGVLLTELAGLEERGIDTSGLILS *:*******:**************:****** ** **::**:** *::* MLBr_00280|M.leprae_Br4923 ADAHLLMPYHVAIDKVTERYMGNKKIGTTGRGIGPCYQDKIARMGIRVAD MAV_4777|M.avium_104 ADAHLLLPYHVAIDKVTERYMGNKKIGTTGRGIGPCYQDKIARIGIRVAD Mb0364c|M.bovis_AF2122/97 ADAHLLMPYHIAIDKVTERYMGSKKIGTTGRGIGPCYQDKIARIGIRVAD Rv0357c|M.tuberculosis_H37Rv ADAHLLMPYHIAIDKVTERYMGSKKIGTTGRGIGPCYQDKIARIGIRVAD MMAR_0680|M.marinum_M ADAHLLMPYHVAIDKVTERYMGSKKIGTTGRGIGPCYQDKVARMGIRVAD MUL_2834|M.ulcerans_Agy99 ADAHLLMPYHVAIDKVTERYMGSKKIGTTGRGIGPCYQDKVARMGIRVAD Mflv_0228|M.gilvum_PYR-GCK ADAHLLMPYHVAIDKVVERYAGSKKIGTTGRGIGPCYQDKIARQGIRVAD Mvan_0677|M.vanbaalenii_PYR-1 ADAHLLMPYHVAIDKVVERYAGSKKIGTTGRGIGPCYQDKIARQGIRVAD MSMEG_0759|M.smegmatis_MC2_155 ADAHLLMPYHVAIDKVVERWAGSKKIGTTGRGIGPCYQDKIARIGIRVAD TH_0134|M.thermoresistible__bu ADAHLLMPYHVAIDKVVERWAGKKKIGTTGRGIGPCYQDKIARIGIRVAD MAB_4249c|M.abscessus_ATCC_199 ADAHLLMPYHVAIDKVTERYLGSKKIGTTGRGIGPCYQDKVARIGIRVAD ******:***:*****.**: *.*****************:** ****** MLBr_00280|M.leprae_Br4923 VLEPGELTHKIEAALEFKNQVLVKIYNRKALDLAQVVETLLEQAQQFRHR MAV_4777|M.avium_104 VLDREVLTHKIEAALELKNQILVKIYNRKALDPHQVVECLLEQAEGFRHR Mb0364c|M.bovis_AF2122/97 VLDPEQLTHKVEAACEFKNQVLVKIYNRKALDPAQVVDALLEQAEGFKHR Rv0357c|M.tuberculosis_H37Rv VLDPEQLTHKVEAACEFKNQVLVKIYNRKALDPAQVVDALLEQAEGFKHR MMAR_0680|M.marinum_M VLDTDQLAHKVEAALEFKNQVLVKIYNRKALDPDQVVESLLEQAEGFRHR MUL_2834|M.ulcerans_Agy99 VLDTDQLAHKVEAALEFKNQVLVKIYNRKALDPDQVVESLLEQAEGFRHR Mflv_0228|M.gilvum_PYR-GCK VLDPAVLAEKIEGALELKNQVLVKIYNRKALEPAEVVENLLEQAEGFKHR Mvan_0677|M.vanbaalenii_PYR-1 VLDPALLAEKIEGALELKNQVLVKIYNRKALDPAEVVENLLEQADGFKHR MSMEG_0759|M.smegmatis_MC2_155 VLDEQVLAEKIEAALEFKNQVLVKIYNRKALEPAEVLENLLEQAEGFKHR TH_0134|M.thermoresistible__bu VLDEQVLAEKIEAALEFKNQVLVKIYNRKALDPTEVFENLLEQAAGFKHR MAB_4249c|M.abscessus_ATCC_199 VLDEESLRQKVHAALEFKNQVLVKIYNRKALDPDQVVDGVLEQAEGFKHR **: * .*:..* *:***:**********: :*.: :**** *:** MLBr_00280|M.leprae_Br4923 ITDTRLLLNDALEAGETVLLEGAQGTLLDVDHGTYPYVTSSNPTAGGAAL MAV_4777|M.avium_104 IADTRLLLNTALEAGETVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAV Mb0364c|M.bovis_AF2122/97 IADTRLLLNAALEAGETVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAV Rv0357c|M.tuberculosis_H37Rv IADTRLLLNAALEAGETVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAV MMAR_0680|M.marinum_M IADARLLLNNALEAGETVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAV MUL_2834|M.ulcerans_Agy99 IADARLLLNNALEAGGTVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAV Mflv_0228|M.gilvum_PYR-GCK IADARLLLNEALERDEIVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGASV Mvan_0677|M.vanbaalenii_PYR-1 IADARLLLNEALERNETVLLEGSQGTLLDVDHGTYPFVTSSNPTAGGASV MSMEG_0759|M.smegmatis_MC2_155 IADARLLLNQALENDEAVLLEGSQGTLLDVDHGTYPFVTSSNPTAGGAAV TH_0134|M.thermoresistible__bu IADTRLLLNNALDNGETVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAV MAB_4249c|M.abscessus_ATCC_199 IADARLQLNQALERGETVLLEGSQGTLLDVDHGTYPFVTSSNPTAGGASV *:*:** ** **: . *****:*************:***********:: MLBr_00280|M.leprae_Br4923 GSGIGPTRIHTVLGILKAYTTRVGSGPFPTELFDENGEYLAKTGSEIGVT MAV_4777|M.avium_104 GSGIGPTRITAVLGILKAYTTRVGSGPFPTELFDENGEYLSKTGGEFGVT Mb0364c|M.bovis_AF2122/97 GSGIGPTRIGTVLGILKAYTTRVGSGPFPTELFDEHGEYLSKTGREFGVT Rv0357c|M.tuberculosis_H37Rv GSGIGPTRIGTVLGILKAYTTRVGSGPFPTELFDEHGEYLSKTGREFGVT MMAR_0680|M.marinum_M GSGIGPTRIRTVLGILKAYTTRVGSGPFPTELFDESGEYLSKTGGEFGVT MUL_2834|M.ulcerans_Agy99 GSGIGPTRIRTVLGILKAYTTRVGSGPFPTELFYESGEYLSKTGGEFGVT Mflv_0228|M.gilvum_PYR-GCK GSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDEHGAYLAKTGGEVGVT Mvan_0677|M.vanbaalenii_PYR-1 GSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDDHGAYLAKTGGEVGVT MSMEG_0759|M.smegmatis_MC2_155 GSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDEHGAYLAKTGGEVGVT TH_0134|M.thermoresistible__bu GSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDDNGAYLAKAGGEVGVT MAB_4249c|M.abscessus_ATCC_199 GSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDEHGAYLAKTGGEVGVT ********* :********************** : * **:*:* *.*** MLBr_00280|M.leprae_Br4923 TGRRRRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPVCVGYQIA MAV_4777|M.avium_104 TGRRRRCGWFDAVVARYATRVNGITDFFLTKLDVLSSLETVPVCVGYRID Mb0364c|M.bovis_AF2122/97 TGRRRRCGWFDAVIARYAARVNGITDYFLTKLDVLSSLESVPVCVGYEID Rv0357c|M.tuberculosis_H37Rv TGRRRRCGWFDAVIARYAARVNGITDYFLTKLDVLSSLESVPVCVGYEID MMAR_0680|M.marinum_M TGRRRRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPVCVGYEID MUL_2834|M.ulcerans_Agy99 TGRRRRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPVCVGYEID Mflv_0228|M.gilvum_PYR-GCK TGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPICVGYTVD Mvan_0677|M.vanbaalenii_PYR-1 TGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPICVGYSVD MSMEG_0759|M.smegmatis_MC2_155 TGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPVCVGYTVD TH_0134|M.thermoresistible__bu TGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPVCVGYRID MAB_4249c|M.abscessus_ATCC_199 TGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLQTVPICVGYEVD *** *********:****:*******:***********::**:**** : MLBr_00280|M.leprae_Br4923 GVRTHDMPITQSDLARAEPIYEELPGWWEDISGAREFEDLPAKARDYVLR MAV_4777|M.avium_104 GARINEMPMTQSDLHRAEPIYEELPGWWEDISAAREFDDLPAKARDYVLR Mb0364c|M.bovis_AF2122/97 GRRTRDMPMTQRDLCRAKPVYEELPGWWEDISGAREFDDLPAKARDYVLR Rv0357c|M.tuberculosis_H37Rv GRRTRDMPMTQRDLCRAKPVYEELPGWWEDISGAREFDDLPAKARDYVLR MMAR_0680|M.marinum_M GKRTSEMPMTQSDLCRAKPVYEELPGWWEDISAAREFDDLPAKARDYVLR MUL_2834|M.ulcerans_Agy99 GKRTSEMPMTQSDLCRAKPVYEELPGWWEDISAAREFDDLPAKARDYVLR Mflv_0228|M.gilvum_PYR-GCK GKRTDEMPMTQSDIARAEPVYEELPGWWEDISGAREFDDLPAKARDYVLR Mvan_0677|M.vanbaalenii_PYR-1 GKRTDEMPMTQSDIARAEPIYEELPGWWEDISGCRTFDELPAKARDYVLR MSMEG_0759|M.smegmatis_MC2_155 GKRVDEMPMTQSDIARAEPVYEELPGWWEDISGAREFEDLPAKARDYVLR TH_0134|M.thermoresistible__bu GKRVDEMPMTQSDVARAEPIYEEMPGWWEDISGAREFEDLPAKARDYVLR MAB_4249c|M.abscessus_ATCC_199 GKRTNEMPMTQSEIYRATPVYEELPGWWEDISGARQFEDLPAKAQDYVLR * * :**:** :: ** *:***:********..* *::*****:***** MLBr_00280|M.leprae_Br4923 LEELAGAQVACIGVGPGRDQTIVRCDVLRSRR- MAV_4777|M.avium_104 LEELAGAHVSCIGVGPGREQTIVRRDILAARP- Mb0364c|M.bovis_AF2122/97 LEQLAGAPVSCIGVGPGREQTIVRRDVLQDRP- Rv0357c|M.tuberculosis_H37Rv LEQLAGAPVSCIGVGPGREQTIVRRDVLQDRP- MMAR_0680|M.marinum_M LEEIAGAPVSCIGVGPGRDQTIVRRDILQERA- MUL_2834|M.ulcerans_Agy99 LEEISGAPVSCIGVGPGRDQTIVRRDILQERA- Mflv_0228|M.gilvum_PYR-GCK LEELAGAHVSCIGVGPGRDQTIVRRDILATS-- Mvan_0677|M.vanbaalenii_PYR-1 LEDLAGAHVSCIGVGPGRDQTIVRRDVLAAR-- MSMEG_0759|M.smegmatis_MC2_155 LEELAGAYVSCIGVGPGRDQTIVRRDVLAAR-- TH_0134|M.thermoresistible__bu VEELAGARVSCIGVGPGRDQTIVRHDVLAASAR MAB_4249c|M.abscessus_ATCC_199 LEELAGAPMSCIGVGPGRDQTIVRRDILSRS-- :*:::** ::********:***** *:*