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VSAARLTGLTVGIDLRRGRASAVVDVLDDVHLDIPAGRVTALVGESGCGKSLVAAALSGLLPPGSRVHGT VHVGGRQVRCDDERAWRALRGRHVGSVPQSAATSFTPVRTVGSQLAEICARLRSDRTPEHLCAAMALPAG VVDRYPHELSGGMAQRVAIAAALAGRPGLLIADEPTSALDPDNAAVIWRLLGDAASDGAGVLVITHDMPS LLRAQVCDEVAVMARGTVLSQAPLSDALGSPDPYTQALLGTVLV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0116 | - | - | 100% (255) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_2259 | - | 2e-35 | 42.13% (235) | oligopeptide/dipeptide ABC transporter, ATPase subunit |
| M. gilvum PYR-GCK | Mflv_2758 | - | 9e-31 | 38.82% (237) | AAA ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3687c | dppD | 2e-37 | 42.79% (229) | peptide ABC transporter ATP-binding protein |
| M. tuberculosis H37Rv | Rv3663c | dppD | 2e-37 | 42.79% (229) | peptide ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_01122 | - | 4e-32 | 40.00% (230) | putative ABC transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_0429 | - | 2e-38 | 42.05% (264) | putative oligopeptide ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_5151 | dppD | 4e-38 | 41.30% (247) | dipeptide-transport ATP-binding protein ABC transporter DppD |
| M. avium 104 | MAV_0467 | dppD | 1e-36 | 42.29% (227) | ABC transporter, ATP-binding protein DppD |
| M. smegmatis MC2 155 | MSMEG_6121 | - | 2e-35 | 39.25% (265) | dipeptide transport ATP-binding protein DppD |
| M. thermoresistible (build 8) | TH_3544 | - | 2e-89 | 67.76% (245) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_4237 | dppD | 2e-38 | 41.30% (247) | dipeptide-transport ATP-binding protein ABC transporter DppD |
| M. vanbaalenii PYR-1 | Mvan_0435 | - | 3e-37 | 41.27% (252) | oligopeptide/dipeptide ABC transporter, ATPase subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6121|M.smegmatis_MC2_155 MTTSANRSATAVLADPALKVDGLCVDIRSMSG----TVRAVDHVSFEAHR
Mvan_0435|M.vanbaalenii_PYR-1 MTR-----------EPLLRVDDLRVSFATEDG----VLQAVDGVSFDLTP
MLBr_01122|M.leprae_Br4923 -------------MSPLLEVTDLAVTFETNGE----PVTAVRGISYRINA
MAB_0429|M.abscessus_ATCC_1997 MEVP--------TSDSVVDITGLTVDFEVDKQ----WVPAVKGVSLSVAK
Mb3687c|M.bovis_AF2122/97 MSVP---------AAPLLSVEGLEVTFGT-------DAPAVCGVDLAVRS
Rv3663c|M.tuberculosis_H37Rv MSVP---------AAPLLSVEGLEVTFGT-------DAPAVCGVDLAVRS
MMAR_5151|M.marinum_M MSTA---------AAPLLSVHGLQVRFGT-------DEPVVAGMDLSVYR
MUL_4237|M.ulcerans_Agy99 MSTA---------AAPLLSVHGLQVRFGT-------DEPVVAGMDLSVYR
MAV_0467|M.avium_104 MAGM---------TTPLLSVEGLHVGFG--------EHAAVRGLDLRVLP
Mflv_0116|M.gilvum_PYR-GCK -------------MVSAARLTGLTVGIDLRRGRASAVVDVLDDVHLDIPA
TH_3544|M.thermoresistible__bu -VVN---------VPTAARLTDLTVDIATRPGRRAPVVRTLTGVDLRVRA
. : .* * : .: :
MSMEG_6121|M.smegmatis_MC2_155 GETLALLGESGCGKSMTATALVGLLEPVASVSAGTAHLGEVDLFSADRKT
Mvan_0435|M.vanbaalenii_PYR-1 GEVLAVVGESGCGKSVTAQTLTGLTRSPNTRISGSVTYRGRELTGLGDDA
MLBr_01122|M.leprae_Br4923 GEVVAMVGESGSGKSAAAMAVVGLL-PEYAQVRGSVRLHNTELVGLADKT
MAB_0429|M.abscessus_ATCC_1997 GEVLAIVGESGSGKSTTAMAIPALL-PPSARVRGSVKLNGAELLGATNDE
Mb3687c|M.bovis_AF2122/97 GQTVAVVGESGSGKSTTAAAILGLLPAGGRITAGRVVFDGRDITGADAKR
Rv3663c|M.tuberculosis_H37Rv GQTVAVVGESGSGKSTTAAAILGLLPAGGRITAGRVVFDGRDITGADAKR
MMAR_5151|M.marinum_M GQTVAVVGESGSGKSTAAAAILGLLAPGGRITAGRIIFDGRDITSADRRV
MUL_4237|M.ulcerans_Agy99 GQTVAVVGESGSGKSTAAAAILGLLAPGGRITAGRIIFDGRDITSADRRV
MAV_0467|M.avium_104 GQTVAVVGESGSGKSSTAAAILGLLPPGGRITAGRIMFDGVDISAADRRA
Mflv_0116|M.gilvum_PYR-GCK GRVTALVGESGCGKSLVAAALSGLL-PPGSRVHGTVHVGGRQVRCDDERA
TH_3544|M.thermoresistible__bu GEVTALIGESGCGKSLVAAALCGLL-PPGSRVTGRITIAGADIAHHDEKR
*.. *::****.*** .* :: .* . * ::
MSMEG_6121|M.smegmatis_MC2_155 RRALAGTELAIVFQDALTALNPLYTVGTQLAEPFRIHQG-LSVREARRKA
Mvan_0435|M.vanbaalenii_PYR-1 LRDIRGEEIAMVFQDPMSSLNPVYRVGDQIVEMIRAHRD-VSKKEARERT
MLBr_01122|M.leprae_Br4923 MSRFRGKAIGTVFQDPMSALTPVYTVGDQITEAIKVHQPRVGKKAAHRRA
MAB_0429|M.abscessus_ATCC_1997 LRAVRGKDVAVIFQEPMTALNPVYTIGWQIAEAVCAHKK-MSRRQARDRA
Mb3687c|M.bovis_AF2122/97 LRSIRGREIGYVPQDPMTNLNPVWKVGFQVTEALRANTD---GRAARRRA
Rv3663c|M.tuberculosis_H37Rv LRSIRGREIGYVPQDPMTNLNPVWKVGFQVTEALRANTD---GRAARRRA
MMAR_5151|M.marinum_M MRTIRGREIGYVPQDPMTNLNPVWKVGFQIREALRANTD---GRDARRRT
MUL_4237|M.ulcerans_Agy99 MRTIRGREIGYVPQDPMTNLNPVWKVGFQIREALRANTD---GRDARRRT
MAV_0467|M.avium_104 LRSMRGRQIGYIPQDPMTNLNPVWKVGFQIREALRANTS---DRDTRRRA
Mflv_0116|M.gilvum_PYR-GCK WRALRGRHVGSVPQSAATSFTPVRTVGSQLAEICARLRS-------DRTP
TH_3544|M.thermoresistible__bu WRRLRGRHIGLVPQSAATSFTPVRPVGDQLAEVCHRLRA-------DRTP
. * :. : *.. : :.*: :* *: * .
MSMEG_6121|M.smegmatis_MC2_155 VELMERVGIPQPESRLHDYPHQFSGGMRQRLLIAMAVALNPTVLIADEPT
Mvan_0435|M.vanbaalenii_PYR-1 VELLTSVGIPNPQARVRSYPHEFSGGMRQRVMIAMALALEPAVLIADEPT
MLBr_01122|M.leprae_Br4923 VELLELVGITQPDRRARAFPHELSGGERQRVVIATAIANDPDLLICDEPT
MAB_0429|M.abscessus_ATCC_1997 VELLDLVDMPEPAKRVKHYPHQLSGGQRQRAMIAQALALDPGLLIADEPT
Mb3687c|M.bovis_AF2122/97 VELLAEAGLPDPAKQAGRYPHQLSGGMCQRALIAIGLAGRPRLLIADEPT
Rv3663c|M.tuberculosis_H37Rv VELLAEAGLPDPAKQAGRYPHQLSGGMCQRALIAIGLAGRPRLLIADEPT
MMAR_5151|M.marinum_M VELLAQAGMPDPDKHAQRYPHQLSGGMCQRALIAIGLAGRPALLIADEPT
MUL_4237|M.ulcerans_Agy99 VELLAQAGMPDPDKHAQRYPHQLSGGMCQRALIAIGLAGRPALLIADEPT
MAV_0467|M.avium_104 VQLLEAAGMPDPAKQAARYPHQLSGGMCQRALIAIGLAGRPRLLIADEPT
Mflv_0116|M.gilvum_PYR-GCK EHLCAAMALP--AGVVDRYPHELSGGMAQRVAIAAALAGRPGLLIADEPT
TH_3544|M.thermoresistible__bu IQLLATVGLT--ADVAARYPHELSGGMAQRVAIAAALAGRPGLLLADEPT
.* :. :**::*** ** ** .:* * :*:.****
MSMEG_6121|M.smegmatis_MC2_155 TALDVTVQAQIMALLRDLRTEYHMAVVLITHDLA--LVVEEADRVAVMYA
Mvan_0435|M.vanbaalenii_PYR-1 TALDVTVQAQILRLLADLNRERELAVVLITHDLG--VVAEVADRVVVMYA
MLBr_01122|M.leprae_Br4923 TALDVTVQAQILEVLKTARDVTGAGVLIITHDLG--VVTEFADQALVMYA
MAB_0429|M.abscessus_ATCC_1997 TALDVTVQAEILDLMRDLRHRIDAGIILITHDMG--VVADMADRIMVMKD
Mb3687c|M.bovis_AF2122/97 SALDVTVQRQVLDHLQGLTDELGTALLLITHDLA--LAAQRAEAVVVVRR
Rv3663c|M.tuberculosis_H37Rv SALDVTVQRQVLDHLQGLTDELGTALLLITHDLA--LAAQRAEAVVVVRR
MMAR_5151|M.marinum_M SALDVTVQRQVLDHLQRRTDELGTALLLITHDLA--LAAERAESVLVVHH
MUL_4237|M.ulcerans_Agy99 SALDVTVQRQVLDHLQRRTDEVGTALLLITHDLA--LAAERAESVLVVDH
MAV_0467|M.avium_104 SALDVTVQRQVLDHLQRLTADLGTAVLLITHDLA--LAAERAESVVVVHD
Mflv_0116|M.gilvum_PYR-GCK SALDPDNAAVIWRLLGDAASD-GAGVLVITHDMPSLLRAQVCDEVAVMAR
TH_3544|M.thermoresistible__bu TGLDPDNAAMVWRLLGEAAAE-GAGVLVITHDLPALMRAQVCAEVALMRA
:.** : : .:::****: : .: . ::
MSMEG_6121|M.smegmatis_MC2_155 GQIVETGPVAEVFANPAHPYTKGLLDSVP-VSAVRGEA----------LA
Mvan_0435|M.vanbaalenii_PYR-1 GQIVEDGTVDDIFYSPQHPYTWGLLGSLARLDRPRTER----------LA
MLBr_01122|M.leprae_Br4923 GRVVESAQVSTLYRERQMPYTVGLLGSVPRLDATQGTR----------LV
MAB_0429|M.abscessus_ATCC_1997 GEVVEQGDAEGIFHRAQQPYTRQLLASVPHLGATLHGR----------DE
Mb3687c|M.bovis_AF2122/97 GVVVESGAAQSILQSPQHEYTRRLVAAAPSLTARSRRPPESR----SRAT
Rv3663c|M.tuberculosis_H37Rv GVVVESGAAQSILQSPQHEYTRRLVAAAPSLTARSRRPPESR----SRAT
MMAR_5151|M.marinum_M GVVVESGTASDILRSPQHEYTKRLVAAAPSLTVRDPRRAPARGPVPGGAD
MUL_4237|M.ulcerans_Agy99 GVVVESGTASDILRSPQHEYTKRLVAAAPSLTVRDPRRAPARGPVPGGAD
MAV_0467|M.avium_104 GVAVESGAAQSILQDPRHEYTRRLVAAAPALTVSGGARTGPR-----QPD
Mflv_0116|M.gilvum_PYR-GCK GTVLSQAPLSDALGSP-DPYTQALLGTVLV--------------------
TH_3544|M.thermoresistible__bu GTVVAQEPLDVMSTRT-DGYVGRFFSPAVL--------------------
* : *. :. .
MSMEG_6121|M.smegmatis_MC2_155 SIGG-APPELSAIPKGCVYQD------RCPHVADICVTTRPV-LEGEH-R
Mvan_0435|M.vanbaalenii_PYR-1 QIAG-APPSLLDPPSGCRFAP------RCAFQFDRCDQPPPLDHDGGT-H
MLBr_01122|M.leprae_Br4923 PIPG-APPSLAGLQQECPFAP------RCPLVVDECRLREPELVEVRAGH
MAB_0429|M.abscessus_ATCC_1997 SNPPPTDLALSVEHAVIEYPG------KSGSFRAVDDVSFTIGRGEVVGL
Mb3687c|M.bovis_AF2122/97 TQAG---DILVVSELTKIYRESRGAPWRRVESRAVDGVSFRLPRASTLAI
Rv3663c|M.tuberculosis_H37Rv TQAG---DILVVSELTKIYRESRGAPWRRVESRAVDGVSFRLPRASTLAI
MMAR_5151|M.marinum_M QPAGGCGDILSVSELTKIYRESRGAPWRRGEFRAVDSVSFRLRRASTLAI
MUL_4237|M.ulcerans_Agy99 QPAGGCGDILSVSELTKIYRESRGAPWRRGEFRAVDSVSFRLRRASTLAI
MAV_0467|M.avium_104 RTQPEPADILVASDLTKLYREPRATLWRRTEFRAVDAVSFRLHRARTLAI
Mflv_0116|M.gilvum_PYR-GCK --------------------------------------------------
TH_3544|M.thermoresistible__bu --------------------------------------------------
MSMEG_6121|M.smegmatis_MC2_155 RAACHFSDRAAGGTGGEHHE------------------------------
Mvan_0435|M.vanbaalenii_PYR-1 LDRCWLG----GDVKAEVRP------------------------------
MLBr_01122|M.leprae_Br4923 RTACIRTDQVSGRSAADIYGINTDTRTSATSDSSVVVRVRDLVKTYRLTK
MAB_0429|M.abscessus_ATCC_1997 VGESGSGKSTIGRAAVGLLRVAS---------------------------
Mb3687c|M.bovis_AF2122/97 VGESGSGKSTLARMVLGLLQPTSG--------------------------
Rv3663c|M.tuberculosis_H37Rv VGESGSGKSTLARMVLGLLQPTSG--------------------------
MMAR_5151|M.marinum_M VGESGSGKSTVARMVLGLLQPTSG--------------------------
MUL_4237|M.ulcerans_Agy99 VGESGSGKSTVARMVLGLLQPTSG--------------------------
MAV_0467|M.avium_104 AGESGSGKSTLALMVLGLLPPTSG--------------------------
Mflv_0116|M.gilvum_PYR-GCK --------------------------------------------------
TH_3544|M.thermoresistible__bu --------------------------------------------------
MSMEG_6121|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0435|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01122|M.leprae_Br4923 GVGLRRAIGEIRAVNGVSFELQQGRTLGIVGESGSGKSTTLHEILRLAVP
MAB_0429|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3687c|M.bovis_AF2122/97 --------------------------------------------------
Rv3663c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5151|M.marinum_M --------------------------------------------------
MUL_4237|M.ulcerans_Agy99 --------------------------------------------------
MAV_0467|M.avium_104 --------------------------------------------------
Mflv_0116|M.gilvum_PYR-GCK --------------------------------------------------
TH_3544|M.thermoresistible__bu --------------------------------------------------
MSMEG_6121|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0435|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01122|M.leprae_Br4923 QSGSIEVLGIDVATLNRASRRSMRRNIQVVFQDPVASLDPRLPVFELIAE
MAB_0429|M.abscessus_ATCC_1997 --GTICVAGQDISTANRKQLRDIRSKVGVVFQDPGSSLNPRWPIGQSIAE
Mb3687c|M.bovis_AF2122/97 -TVVFDGT-YDVGALARDQVLAFRRRVQPVFQNPYSSLDPMYSVFRAIEE
Rv3663c|M.tuberculosis_H37Rv -TVVFDGT-YDVGALARDQVLAFRRRVQPVFQNPYSSLDPMYSVFRAIEE
MMAR_5151|M.marinum_M -TVSFDGARIQPDKLDRDAQLAFRRRIQPVFQNPYSSLDPMYSVFRAIEE
MUL_4237|M.ulcerans_Agy99 -TVSFDGARIQPDKLDRDAQLAFRCRIQPVFQNPYSSLDPMYSVFRAIEE
MAV_0467|M.avium_104 -TVVFDGTRIDDT-LSGDQHLAFRRRVQPVFQNPYSSLDPMYSVFRAIEE
Mflv_0116|M.gilvum_PYR-GCK --------------------------------------------------
TH_3544|M.thermoresistible__bu --------------------------------------------------
MSMEG_6121|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0435|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01122|M.leprae_Br4923 PLHAN-GFSKNYTQMRVAELLDIVGLRRDDATRYPTEFSGGQKQRIGIAR
MAB_0429|M.abscessus_ATCC_1997 PLTLHTDMDRTQREGRVKTLLEQVQLPAAMRNRFPHQLSGGQRQRVGIAR
Mb3687c|M.bovis_AF2122/97 PLRVHHVGDRRQRQRAVRELVDQVALPSSILGRRPRELSGGQRQRVAIAR
Rv3663c|M.tuberculosis_H37Rv PLRVHHVGDRRQRQRAVRELVDQVALPSSILGRRPRELSGGQRQRVAIAR
MMAR_5151|M.marinum_M PLRIHRVGDRAQRRQMVAELVDQVALPSSVLGRLPRELSGGQRQRVAIAR
MUL_4237|M.ulcerans_Agy99 PLRIHRVGDRGQRRQMVAELVDQVALPSSVLGRLPRELSGGQRQRVAIAR
MAV_0467|M.avium_104 PLRIHRVGDRRQRAKAVHDLVDQVALPSSVLNRLPRELSGGQRQRVAIAR
Mflv_0116|M.gilvum_PYR-GCK --------------------------------------------------
TH_3544|M.thermoresistible__bu --------------------------------------------------
MSMEG_6121|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0435|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01122|M.leprae_Br4923 ALALQPKILAFDEPVSALDVSIQAGIINLLLDLQDRLGLSYLFVSHDLSV
MAB_0429|M.abscessus_ATCC_1997 ALALEPTLLIADEPTSALDVSVQATVLDLFAELQREHGFACLFISHDLAV
Mb3687c|M.bovis_AF2122/97 ALALRPEVLVCDEAVSALDVLVQAQILDLLADLQADLGLTYLFISHDLAV
Rv3663c|M.tuberculosis_H37Rv ALALRPEVLVCDEAVSALDVLVQAQILDLLADLQADLGLTYLFISHDLAV
MMAR_5151|M.marinum_M ALALRPDVLVCDEAVSALDVLVQAQILDLLAELQADLGLAYLFISHDLAV
MUL_4237|M.ulcerans_Agy99 ALALRPDVLVCDEAVSALDVLVQAQILDLLAELQADLGLAYLFISHDLAV
MAV_0467|M.avium_104 ALALRPQVLVCDEAVSALDVLVQAQILELLARLQAELGLAYLFISHDLAV
Mflv_0116|M.gilvum_PYR-GCK --------------------------------------------------
TH_3544|M.thermoresistible__bu --------------------------------------------------
MSMEG_6121|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0435|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01122|M.leprae_Br4923 IKHLAHQVAVMLAGTIVEQGDSHDVFRNPQHDYTRRLLGAIPRPEVG---
MAB_0429|M.abscessus_ATCC_1997 VELVASRIAVLNRGRLAEFGSDTQVLTAPKDDYTKRLLAAVPVPDPEQQR
Mb3687c|M.bovis_AF2122/97 IRQIADDVLVMRAGRVVEHASTEEVFSRPRHEYTRQLLQAIPGAPSAPRK
Rv3663c|M.tuberculosis_H37Rv IRQIADDVLVMRAGRVVEHASTEEVFSRPRHEYTRQLLQAIPGAPSAPRK
MMAR_5151|M.marinum_M VRQISDDVLVMRAGQVVEHAPTEEVFTRPGAQYTQRLLEAIPGGPVAPR-
MUL_4237|M.ulcerans_Agy99 VRQISDDVLVMRAGQVVEHAPTEEVFTRPGAQYTQRLLEAIPGGPVAPR-
MAV_0467|M.avium_104 IRQIADDVLVMRAGRVVEQAPTEKLFTAPAQDYTRQLLDAIPRPRRGGDR
Mflv_0116|M.gilvum_PYR-GCK --------------------------------------------------
TH_3544|M.thermoresistible__bu --------------------------------------------------
MSMEG_6121|M.smegmatis_MC2_155 ----------
Mvan_0435|M.vanbaalenii_PYR-1 ----------
MLBr_01122|M.leprae_Br4923 ----------
MAB_0429|M.abscessus_ATCC_1997 IRREERQALR
Mb3687c|M.bovis_AF2122/97 VGNL------
Rv3663c|M.tuberculosis_H37Rv VGNL------
MMAR_5151|M.marinum_M ----------
MUL_4237|M.ulcerans_Agy99 ----------
MAV_0467|M.avium_104 LSSCDG----
Mflv_0116|M.gilvum_PYR-GCK ----------
TH_3544|M.thermoresistible__bu ----------