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TREPLLRVDDLRVSFATEDGVLQAVDGVSFDLTPGEVLAVVGESGCGKSVTAQTLTGLTRSPNTRISGSV TYRGRELTGLGDDALRDIRGEEIAMVFQDPMSSLNPVYRVGDQIVEMIRAHRDVSKKEARERTVELLTSV GIPNPQARVRSYPHEFSGGMRQRVMIAMALALEPAVLIADEPTTALDVTVQAQILRLLADLNRERELAVV LITHDLGVVAEVADRVVVMYAGQIVEDGTVDDIFYSPQHPYTWGLLGSLARLDRPRTERLAQIAGAPPSL LDPPSGCRFAPRCAFQFDRCDQPPPLDHDGGTHLDRCWLGGDVKAEVRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0435 | - | - | 100% (330) | oligopeptide/dipeptide ABC transporter, ATPase subunit |
| M. vanbaalenii PYR-1 | Mvan_1021 | - | 3e-83 | 49.55% (331) | oligopeptide/dipeptide ABC transporter, ATPase subunit |
| M. vanbaalenii PYR-1 | Mvan_4432 | - | 1e-80 | 52.06% (315) | oligopeptide/dipeptide ABC transporter, ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1312c | oppD | 5e-83 | 55.03% (298) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_2259 | - | 5e-80 | 51.40% (321) | oligopeptide/dipeptide ABC transporter, ATPase subunit |
| M. tuberculosis H37Rv | Rv1281c | oppD | 5e-83 | 55.03% (298) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. leprae Br4923 | MLBr_01122 | - | 4e-78 | 52.35% (298) | putative ABC transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_0429 | - | 3e-72 | 51.15% (262) | putative oligopeptide ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_4138 | oppD | 3e-86 | 54.11% (316) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. avium 104 | MAV_1431 | oppD | 6e-86 | 54.11% (316) | ABC transporter, ATP-binding protein OppD |
| M. smegmatis MC2 155 | MSMEG_0640 | - | 1e-138 | 75.08% (325) | oligopeptide transport ATP-binding protein OppD |
| M. thermoresistible (build 8) | TH_3537 | - | 8e-84 | 54.13% (303) | PUTATIVE oligopeptide/dipeptide ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_4001 | oppD | 1e-85 | 53.80% (316) | oligopeptide-transport ATP-binding protein ABC transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0435|M.vanbaalenii_PYR-1 ---MTREPLLRVDDLRVSFATEDGVLQAVDGVSFDLTPGEVLAVVGESGC
MSMEG_0640|M.smegmatis_MC2_155 ---MS--ALLQVNDLRVSFTTDGGVVRAVDGVSFDLKRGEILAVVGESGS
Mb1312c|M.bovis_AF2122/97 ---MS--PLLEVTDLAVTFRTDGDPVTAVRGISYRVEPGEVVAMVGESGS
Rv1281c|M.tuberculosis_H37Rv ---MS--PLLEVTDLAVTFRTDGDPVTAVRGISYRVEPGEVVAMVGESGS
MLBr_01122|M.leprae_Br4923 ---MS--PLLEVTDLAVTFETNGEPVTAVRGISYRINAGEVVAMVGESGS
MMAR_4138|M.marinum_M ---MN--PLLEVTDLAVTFPTENDPVTAVRGISYQVAPGEVVAMVGESGS
MUL_4001|M.ulcerans_Agy99 ---MN--PLLEVTDLAVTFPTENDPVTAVRGISYQVAPGEVVAVVGESGS
MAV_1431|M.avium_104 ---MS--PLLQVTDLAVTFPAGDAPVTAVRGISYRIEPGEVVAMVGESGS
Mflv_2259|M.gilvum_PYR-GCK ----M--SLLEVRGLHVTFPTDTEAVPAVRGLDYHVESGEVVALVGESGA
TH_3537|M.thermoresistible__bu --MTS--PLLEVNDLTVTFPTDTDPVAAVRGMTFSVHPREVVALVGESGA
MAB_0429|M.abscessus_ATCC_1997 MEVPTSDSVVDITGLTVDFEVDKQWVPAVKGVSLSVAKGEVLAIVGESGS
.:: : .* * * . : ** *: : *::*:*****.
Mvan_0435|M.vanbaalenii_PYR-1 GKSVTAQTLTGLTRSPNTRISGSVTYRGRELTGLGDDALRDIRGEEIAMV
MSMEG_0640|M.smegmatis_MC2_155 GKSVTAQTLIGLTRASNSAITGAIDFDGRDINSLDDGALREIRGEHIAMV
Mb1312c|M.bovis_AF2122/97 GKSAAAMAVVGLLP-EYAQVRGSVRLQGTELLGLADNAMSRFRGKAIGTV
Rv1281c|M.tuberculosis_H37Rv GKSAAAMAVVGLLP-EYAQVRGSVRLQGTELLGLADNAMSRFRGKAIGTV
MLBr_01122|M.leprae_Br4923 GKSAAAMAVVGLLP-EYAQVRGSVRLHNTELVGLADKTMSRFRGKAIGTV
MMAR_4138|M.marinum_M GKSAAAMAVVGLLP-EYAKVRGSVRLQGTELLGLADDAMSRFRGKVIGTV
MUL_4001|M.ulcerans_Agy99 GKSAAAMAVVGLLP-EYAKVRGSVRLQGTELLGLADDAMSRFRGKVIGTV
MAV_1431|M.avium_104 GKSVSAMAVMGLLP-EHARVRGSVRLHDTELLGLGDDAMSRLRGRAVGMV
Mflv_2259|M.gilvum_PYR-GCK GKSAGAMAVVGLLP-EWAEVSGSVRLDGDELLGLDDRQMSRIRGARIGTV
TH_3537|M.thermoresistible__bu GKSASAMAVVGLLP-EYAQVSGSVRLQGRELLGLSDRQMSAIRGRSIGTV
MAB_0429|M.abscessus_ATCC_1997 GKSTTAMAIPALLP-PSARVRGSVKLNGAELLGATNDELRAVRGKDVAVI
***. * :: .* : : *:: . :: . : : .** :. :
Mvan_0435|M.vanbaalenii_PYR-1 FQDPMSSLNPVYRVGDQIVEMIRAHR-DVSKKEARERTVELLTSVGIPNP
MSMEG_0640|M.smegmatis_MC2_155 FQDPMTSLNPVYRVGDQIIEMIRAHR-DVSKAEARDKAVELLRAVGIPHP
Mb1312c|M.bovis_AF2122/97 FQDPMSALTPVYTVGDQIAEAIEVHQPRVGKKAARRRAVELLDLVGISQP
Rv1281c|M.tuberculosis_H37Rv FQDPMSALTPVYTVGDQIAEAIEVHQPRVGKKAARRRAVELLDLVGISQP
MLBr_01122|M.leprae_Br4923 FQDPMSALTPVYTVGDQITEAIKVHQPRVGKKAAHRRAVELLELVGITQP
MMAR_4138|M.marinum_M FQDPMSALTPVYTVGDQIAETIEIHQPTFSKKAARRRAVELLELVGIAQP
MUL_4001|M.ulcerans_Agy99 FQDPMSALTPVYTVGDQIAETIEIHQPTFSRKAARRRAVELLELVGIAQP
MAV_1431|M.avium_104 FQDPMSALTPVYTVGDQIAEAITIHQPRVGRKAARDRAVELLELVGIAQP
Mflv_2259|M.gilvum_PYR-GCK FQDPMSALTPVYPVGDQIAEAVRIHQRGVDARAARARAVDLLELVGISQP
TH_3537|M.thermoresistible__bu FQDPMSALTPVYTVGDQIAEALQVHQRDLSRRAARARAVELLELVGINQP
MAB_0429|M.abscessus_ATCC_1997 FQEPMTALNPVYTIGWQIAEAVCAHK-KMSRRQARDRAVELLDLVDMPEP
**:**::*.*** :* ** * : *: .. *: ::*:** *.: .*
Mvan_0435|M.vanbaalenii_PYR-1 QARVRSYPHEFSGGMRQRVMIAMALALEPAVLIADEPTTALDVTVQAQIL
MSMEG_0640|M.smegmatis_MC2_155 EQRVSDYPHEFSGGMRQRVMIAMALALEPEVLIADEPTTALDVTVQAQIL
Mb1312c|M.bovis_AF2122/97 QRRSRAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQIL
Rv1281c|M.tuberculosis_H37Rv QRRSRAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQIL
MLBr_01122|M.leprae_Br4923 DRRARAFPHELSGGERQRVVIATAIANDPDLLICDEPTTALDVTVQAQIL
MMAR_4138|M.marinum_M ERRARAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQIL
MUL_4001|M.ulcerans_Agy99 ERRARAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQIL
MAV_1431|M.avium_104 QRRARAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQIL
Mflv_2259|M.gilvum_PYR-GCK AQRARAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQIL
TH_3537|M.thermoresistible__bu ERRARSFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQIL
MAB_0429|M.abscessus_ATCC_1997 AKRVKHYPHQLSGGQRQRAMIAQALALDPGLLIADEPTTALDVTVQAEIL
* :**::*** ***.:** *:* :* :**.*************:**
Mvan_0435|M.vanbaalenii_PYR-1 RLLADLNRERELAVVLITHDLGVVAEVADRVVVMYAGQIVEDGTVDDIFY
MSMEG_0640|M.smegmatis_MC2_155 RLVDRLNQERELAVVLITHDLGVVAEVADRVVVMYAGQIVEDGTLDEIFY
Mb1312c|M.bovis_AF2122/97 DVLKAARDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVESAGVNDLYR
Rv1281c|M.tuberculosis_H37Rv DVLKAARDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVESAGVNDLYR
MLBr_01122|M.leprae_Br4923 EVLKTARDVTGAGVLIITHDLGVVTEFADQALVMYAGRVVESAQVSTLYR
MMAR_4138|M.marinum_M DVLKTARDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVEKATVNDLYH
MUL_4001|M.ulcerans_Agy99 DVLKTARDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVEKATVNDLYH
MAV_1431|M.avium_104 EVLKTARDITGAGVLIITHDLGVVAELADRALVMYAGRVVESAAVASLYR
Mflv_2259|M.gilvum_PYR-GCK DVLRTARDVTGAGVLIITHDLGVVAEFADRALVMYAGRAVEAAPVSDLYR
TH_3537|M.thermoresistible__bu DVLKTARDVTGAGVLVITHDLGVVAEFADRALVMYAGRAVEVASVQQLYR
MAB_0429|M.abscessus_ATCC_1997 DLMRDLRHRIDAGIILITHDMGVVADMADRIMVMKDGEVVEQGDAEGIFH
:: . .:::****:***::.**: :** *. ** . ::
Mvan_0435|M.vanbaalenii_PYR-1 SPQHPYTWGLLGSLARLDRPRTERLAQIAGAPPSLLDPPSGCRFAPRCAF
MSMEG_0640|M.smegmatis_MC2_155 DPQHPYTWGLLGSLPRVEDTNQERLQQIPGQPPSLLNPPTGCRFAARCAH
Mb1312c|M.bovis_AF2122/97 DRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLAPGCPFAPRCPL
Rv1281c|M.tuberculosis_H37Rv DRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLAPGCPFAPRCPL
MLBr_01122|M.leprae_Br4923 ERQMPYTVGLLGSVPRLDATQGTRLVPIPGAPPSLAGLQQECPFAPRCPL
MMAR_4138|M.marinum_M NRRMPYTIGLLGSVPRLDATQGTRLVPIPGAPPSLAGLDRGCPFAPRCPL
MUL_4001|M.ulcerans_Agy99 NRRMPYTIGLLGSVPRLDATQGTRLVPIPGAPPSPAGLDRGCPFAPRCPL
MAV_1431|M.avium_104 DRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLDPGCPFAPRCPL
Mflv_2259|M.gilvum_PYR-GCK NRRMPYTAGLLGSVPRLDATQGTRLVPIPGAPPSVTNLPPGCPFTPRCPL
TH_3537|M.thermoresistible__bu DRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPPAMTDLPPGCPFAPRCPL
MAB_0429|M.abscessus_ATCC_1997 RAQQPYTRQLLASVPHLGATLHGRDESNP--PPT--------DLALSVEH
: *** **.*:.:: . * . **: ::
Mvan_0435|M.vanbaalenii_PYR-1 QFDRCD-QPPPL-DHDGG--------------------------------
MSMEG_0640|M.smegmatis_MC2_155 AFSKCT-QPPPLEDRKGD--------------------------------
Mb1312c|M.bovis_AF2122/97 VIDECLTAEPELLDVATDHRAACIRTELVTGRSAADIYRVKTEARPA-AL
Rv1281c|M.tuberculosis_H37Rv VIDECLTAEPELLDVATDHRAACIRTELVTGRSAADIYRVKTEARPA-AL
MLBr_01122|M.leprae_Br4923 VVDECRLREPELVEVRAGHRTACIRTDQVSGRSAADIYGINTDTRTS-AT
MMAR_4138|M.marinum_M VIDECRSDEPELIEVGQNHRAACIRTDQVNGRSAADIYGVQTEATEP-AP
MUL_4001|M.ulcerans_Agy99 VIDECRSDEPELIEVGQNHRAACIRTDQVNGRSAADIYGVQTEATEP-AP
MAV_1431|M.avium_104 AIDECRSQEPELLPVGPDHRAACIRTDQVDGRSAADIYGVRTQPHPG-EP
Mflv_2259|M.gilvum_PYR-GCK AVDECSTAEPPLESVAPNHQVACIRNGDVAGRSAAEIYGVSTSPPRTEAA
TH_3537|M.thermoresistible__bu AIDDCRAAEPELLEITP------------AG-------------------
MAB_0429|M.abscessus_ATCC_1997 AVIEYPGKSGSF--------------------------------------
. :
Mvan_0435|M.vanbaalenii_PYR-1 -------------------------------THLDRCWLGGDVKAEVRP-
MSMEG_0640|M.smegmatis_MC2_155 -------------------------------GHLDRCWLTPEEKRTLR--
Mb1312c|M.bovis_AF2122/97 GDASVVVRVRHLVKTYRLAKGVVLRRAIGEVRAVDGISLELRQGRTLGIV
Rv1281c|M.tuberculosis_H37Rv GDASVVVRVRHLVKTYRLAKGVVLRRAIGEVRAVDGISLELRQGRTLGIV
MLBr_01122|M.leprae_Br4923 SDSSVVVRVRDLVKTYRLTKGVGLRRAIGEIRAVNGVSFELQQGRTLGIV
MMAR_4138|M.marinum_M ADSSVVVRVSDLVKTYPLTKGVLLRRSIGEVRAVDGVNFELRQGHTLGIV
MUL_4001|M.ulcerans_Agy99 ADSSVVVRVSDLVKTYPLTKGVLLRRSIGEVRAVDGVSFELRQGHTLGIV
MAV_1431|M.avium_104 ANSPVVVRVRELSKTYRLTKG-VLRRSAGEVRAVDRISFQLRQGRTLGIV
Mflv_2259|M.gilvum_PYR-GCK SEDAVALRVEGLTKTFTLTKGLVFRRRIGEVRAVDGISFELQQGRTLGIV
TH_3537|M.thermoresistible__bu -------------------------PGHGEHRAAX---XXLASAVALGTR
MAB_0429|M.abscessus_ATCC_1997 -------------------------------RAVDDVSFTIGRGEVVGLV
:
Mvan_0435|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0640|M.smegmatis_MC2_155 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 GESGSGKSTTLHEILELAAPQSGSIEVLGTDVATLGTAERRSLRRDIQVV
Rv1281c|M.tuberculosis_H37Rv GESGSGKSTTLHEILELAAPQSGSIEVLGTDVATLGTAERRSLRRDIQVV
MLBr_01122|M.leprae_Br4923 GESGSGKSTTLHEILRLAVPQSGSIEVLGIDVATLNRASRRSMRRNIQVV
MMAR_4138|M.marinum_M GESGSGKSTTLHQILELAAPQSGSIEVLGTDVTTLTASSRRALRRDIQVV
MUL_4001|M.ulcerans_Agy99 GESGSGKSTTLHQILELAAPQSGSIEVLGTDVTTLTASSRRALRRDIQVV
MAV_1431|M.avium_104 GESGSGKSTTLHEILELVAPQSGSIEVLGTDVAALSPASRRSLRRDIQVV
Mflv_2259|M.gilvum_PYR-GCK GESGSGKSTTLHQILELSPPQAGTIEVLGRDVAALDRAGRRALRSDLQVV
TH_3537|M.thermoresistible__bu RPGG----------------------------------------------
MAB_0429|M.abscessus_ATCC_1997 GESGSGKSTIGRAAVGLLRVASGTICVAGQDISTANRKQLRDIRSKVGVV
Mvan_0435|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0640|M.smegmatis_MC2_155 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 FQDPVASLDPRLPVFDLIAEPLQAN-GFGKNETHARVAELLDIVGLRHGD
Rv1281c|M.tuberculosis_H37Rv FQDPVASLDPRLPVFDLIAEPLQAN-GFGKNETHARVAELLDIVGLRHGD
MLBr_01122|M.leprae_Br4923 FQDPVASLDPRLPVFELIAEPLHAN-GFSKNYTQMRVAELLDIVGLRRDD
MMAR_4138|M.marinum_M FQDPVASLDPRLPISDLLAEPLQAN-GFNKTDTQDRVAELLDIVGLRRSD
MUL_4001|M.ulcerans_Agy99 FQDPVASLDPRLPISDLLAEPLQAN-GFNKTDTQDRVAELLDIVGLRRSD
MAV_1431|M.avium_104 FQDPVASLDPRLPVFELLAEPLRAN-GFDKDHTNARVAELLETVGLRRAD
Mflv_2259|M.gilvum_PYR-GCK FQDPVASLDPRLPVFDILAEPLQDN-GFDKAAIRDRIAELLGVVGLRRED
TH_3537|M.thermoresistible__bu --------------------------------------------------
MAB_0429|M.abscessus_ATCC_1997 FQDPGSSLNPRWPIGQSIAEPLTLHTDMDRTQREGRVKTLLEQVQLPAAM
Mvan_0435|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0640|M.smegmatis_MC2_155 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 ASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGIINLL
Rv1281c|M.tuberculosis_H37Rv ASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGIINLL
MLBr_01122|M.leprae_Br4923 ATRYPTEFSGGQKQRIGIARALALQPKILAFDEPVSALDVSIQAGIINLL
MMAR_4138|M.marinum_M ASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGIINLL
MUL_4001|M.ulcerans_Agy99 ASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGIINLL
MAV_1431|M.avium_104 AARYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGIINLL
Mflv_2259|M.gilvum_PYR-GCK ASRYPAEFSGGQKQRIGIARALALRPKILALDEPVSALDVSIQAGIVNLL
TH_3537|M.thermoresistible__bu --------------------------------------------------
MAB_0429|M.abscessus_ATCC_1997 RNRFPHQLSGGQRQRVGIARALALEPTLLIADEPTSALDVSVQATVLDLF
Mvan_0435|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0640|M.smegmatis_MC2_155 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 LDLQEQFGLSYLFVSHDLSVVKHLAHQVAVMLAGTVVEQGDSEEVFGNPK
Rv1281c|M.tuberculosis_H37Rv LDLQEQFGLSYLFVSHDLSVVKHLAHQVAVMLAGTVVEQGDSEEVFGNPK
MLBr_01122|M.leprae_Br4923 LDLQDRLGLSYLFVSHDLSVIKHLAHQVAVMLAGTIVEQGDSHDVFRNPQ
MMAR_4138|M.marinum_M LDLQARFKLSYLFVSHDLSVVKHLAHSVVVMFAGSIVEQGNSQEVFSNPQ
MUL_4001|M.ulcerans_Agy99 LDLQAGFKLSYLFVSHDLSVVKHLANSVVVMFAGSIVEQGNSQEVFSNPQ
MAV_1431|M.avium_104 LDLQAQFQLSYLFVSHDLSVVKHLAHDVAVMYAGSIVEQGDSSQVFGNPQ
Mflv_2259|M.gilvum_PYR-GCK LDLQERFGLAYLFVSHDLSVVRHLAHRVAVMNKGVIVEQGDSDQVFGSPR
TH_3537|M.thermoresistible__bu --------------------------------------------------
MAB_0429|M.abscessus_ATCC_1997 AELQREHGFACLFISHDLAVVELVASRIAVLNRGRLAEFGSDTQVLTAPK
Mvan_0435|M.vanbaalenii_PYR-1 ------------------------------
MSMEG_0640|M.smegmatis_MC2_155 ------------------------------
Mb1312c|M.bovis_AF2122/97 HEYTRRLLGAVPQPDPARRG----------
Rv1281c|M.tuberculosis_H37Rv HEYTRRLLGAVPQPDPARRG----------
MLBr_01122|M.leprae_Br4923 HDYTRRLLGAIPRPEVG-------------
MMAR_4138|M.marinum_M HEYTQRLLGAVPQPIPGNAD----------
MUL_4001|M.ulcerans_Agy99 HEYTQRLLGAVPQPIPGNAD----------
MAV_1431|M.avium_104 HEYTRRLLDAVPQPNPGSRG----------
Mflv_2259|M.gilvum_PYR-GCK HDYTRRLLDAVPRPQADRR-----------
TH_3537|M.thermoresistible__bu ------------------------------
MAB_0429|M.abscessus_ATCC_1997 DDYTKRLLAAVPVPDPEQQRIRREERQALR