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TTSANRSATAVLADPALKVDGLCVDIRSMSGTVRAVDHVSFEAHRGETLALLGESGCGKSMTATALVGLL EPVASVSAGTAHLGEVDLFSADRKTRRALAGTELAIVFQDALTALNPLYTVGTQLAEPFRIHQGLSVREA RRKAVELMERVGIPQPESRLHDYPHQFSGGMRQRLLIAMAVALNPTVLIADEPTTALDVTVQAQIMALLR DLRTEYHMAVVLITHDLALVVEEADRVAVMYAGQIVETGPVAEVFANPAHPYTKGLLDSVPVSAVRGEAL ASIGGAPPELSAIPKGCVYQDRCPHVADICVTTRPVLEGEHRRAACHFSDRAAGGTGGEHHE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6121 | - | - | 100% (343) | dipeptide transport ATP-binding protein DppD |
| M. smegmatis MC2 155 | MSMEG_0640 | - | 3e-82 | 54.15% (301) | oligopeptide transport ATP-binding protein OppD |
| M. smegmatis MC2 155 | MSMEG_4997 | oppD | 1e-71 | 46.97% (330) | ABC transporter, ATP-binding protein OppD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1312c | oppD | 1e-69 | 44.38% (329) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_2259 | - | 2e-72 | 46.48% (327) | oligopeptide/dipeptide ABC transporter, ATPase subunit |
| M. tuberculosis H37Rv | Rv1281c | oppD | 1e-69 | 44.38% (329) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. leprae Br4923 | MLBr_01122 | - | 2e-68 | 43.47% (329) | putative ABC transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_0429 | - | 1e-63 | 48.26% (259) | putative oligopeptide ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_4138 | oppD | 1e-71 | 45.76% (330) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. avium 104 | MAV_1431 | oppD | 1e-69 | 44.98% (329) | ABC transporter, ATP-binding protein OppD |
| M. thermoresistible (build 8) | TH_3537 | - | 6e-72 | 45.54% (336) | PUTATIVE oligopeptide/dipeptide ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_4001 | oppD | 1e-70 | 45.45% (330) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_1021 | - | 1e-140 | 76.58% (333) | oligopeptide/dipeptide ABC transporter, ATPase subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1312c|M.bovis_AF2122/97 ------------------MSPLLEVTDLAVTFRTDGDPVTAVRGISYRVE
Rv1281c|M.tuberculosis_H37Rv ------------------MSPLLEVTDLAVTFRTDGDPVTAVRGISYRVE
MLBr_01122|M.leprae_Br4923 ------------------MSPLLEVTDLAVTFETNGEPVTAVRGISYRIN
MMAR_4138|M.marinum_M ------------------MNPLLEVTDLAVTFPTENDPVTAVRGISYQVA
MUL_4001|M.ulcerans_Agy99 ------------------MNPLLEVTDLAVTFPTENDPVTAVRGISYQVA
MAV_1431|M.avium_104 ------------------MSPLLQVTDLAVTFPAGDAPVTAVRGISYRIE
Mflv_2259|M.gilvum_PYR-GCK ------------------MS-LLEVRGLHVTFPTDTEAVPAVRGLDYHVE
TH_3537|M.thermoresistible__bu -----------------MTSPLLEVNDLTVTFPTDTDPVAAVRGMTFSVH
MAB_0429|M.abscessus_ATCC_1997 -------------MEVPTSDSVVDITGLTVDFEVDKQWVPAVKGVSLSVA
MSMEG_6121|M.smegmatis_MC2_155 MTTSANRSAT-----AVLADPALKVDGLCVDIRSMSGTVRAVDHVSFEAH
Mvan_1021|M.vanbaalenii_PYR-1 MTAFVGHDAHPADVDTHNADPVLDVDGLTVEVRTIGGTLRAVTGVSFQAR
. :.: .* * . : ** :
Mb1312c|M.bovis_AF2122/97 PGEVVAMVGESGSGKSAAAMAVVGLLPEYAQVRGSVRLQG-----TELLG
Rv1281c|M.tuberculosis_H37Rv PGEVVAMVGESGSGKSAAAMAVVGLLPEYAQVRGSVRLQG-----TELLG
MLBr_01122|M.leprae_Br4923 AGEVVAMVGESGSGKSAAAMAVVGLLPEYAQVRGSVRLHN-----TELVG
MMAR_4138|M.marinum_M PGEVVAMVGESGSGKSAAAMAVVGLLPEYAKVRGSVRLQG-----TELLG
MUL_4001|M.ulcerans_Agy99 PGEVVAVVGESGSGKSAAAMAVVGLLPEYAKVRGSVRLQG-----TELLG
MAV_1431|M.avium_104 PGEVVAMVGESGSGKSVSAMAVMGLLPEHARVRGSVRLHD-----TELLG
Mflv_2259|M.gilvum_PYR-GCK SGEVVALVGESGAGKSAGAMAVVGLLPEWAEVSGSVRLDG-----DELLG
TH_3537|M.thermoresistible__bu PREVVALVGESGAGKSASAMAVVGLLPEYAQVSGSVRLQG-----RELLG
MAB_0429|M.abscessus_ATCC_1997 KGEVLAIVGESGSGKSTTAMAIPALLPPSARVRGSVKLNG-----AELLG
MSMEG_6121|M.smegmatis_MC2_155 RGETLALLGESGCGKSMTATALVGLLEPVASVSAGTAHLG----EVDLFS
Mvan_1021|M.vanbaalenii_PYR-1 RGETLALLGESGCGKSMTATALVGLLDPVADIVGGTALLAGRQDRVDLLS
*.:*::****.*** * *: .** * : ... :*..
Mb1312c|M.bovis_AF2122/97 LADNAMSRFRGKAIGTVFQDPMSALTPVYTVGDQIAEAIEVHQPRVGKKA
Rv1281c|M.tuberculosis_H37Rv LADNAMSRFRGKAIGTVFQDPMSALTPVYTVGDQIAEAIEVHQPRVGKKA
MLBr_01122|M.leprae_Br4923 LADKTMSRFRGKAIGTVFQDPMSALTPVYTVGDQITEAIKVHQPRVGKKA
MMAR_4138|M.marinum_M LADDAMSRFRGKVIGTVFQDPMSALTPVYTVGDQIAETIEIHQPTFSKKA
MUL_4001|M.ulcerans_Agy99 LADDAMSRFRGKVIGTVFQDPMSALTPVYTVGDQIAETIEIHQPTFSRKA
MAV_1431|M.avium_104 LGDDAMSRLRGRAVGMVFQDPMSALTPVYTVGDQIAEAITIHQPRVGRKA
Mflv_2259|M.gilvum_PYR-GCK LDDRQMSRIRGARIGTVFQDPMSALTPVYPVGDQIAEAVRIHQRGVDARA
TH_3537|M.thermoresistible__bu LSDRQMSAIRGRSIGTVFQDPMSALTPVYTVGDQIAEALQVHQRDLSRRA
MAB_0429|M.abscessus_ATCC_1997 ATNDELRAVRGKDVAVIFQEPMTALNPVYTIGWQIAEAVCAHK-KMSRRQ
MSMEG_6121|M.smegmatis_MC2_155 ADRKTRRALAGTELAIVFQDALTALNPLYTVGTQLAEPFRIHQ-GLSVRE
Mvan_1021|M.vanbaalenii_PYR-1 MDRRKRREMAGTELAIVFQDALTALNPLYTVGTQLAEPFRIHQ-GLSARE
. * :. :**:.::**.*:*.:* *::*.. *: .. :
Mb1312c|M.bovis_AF2122/97 ARRRAVELLDLVGISQPQRRSRAFPHELSGGERQRVVIAIAIANDPDLLI
Rv1281c|M.tuberculosis_H37Rv ARRRAVELLDLVGISQPQRRSRAFPHELSGGERQRVVIAIAIANDPDLLI
MLBr_01122|M.leprae_Br4923 AHRRAVELLELVGITQPDRRARAFPHELSGGERQRVVIATAIANDPDLLI
MMAR_4138|M.marinum_M ARRRAVELLELVGIAQPERRARAFPHELSGGERQRVVIAIAIANDPDLLI
MUL_4001|M.ulcerans_Agy99 ARRRAVELLELVGIAQPERRARAFPHELSGGERQRVVIAIAIANDPDLLI
MAV_1431|M.avium_104 ARDRAVELLELVGIAQPQRRARAFPHELSGGERQRVVIAIAIANDPDLLI
Mflv_2259|M.gilvum_PYR-GCK ARARAVDLLELVGISQPAQRARAFPHELSGGERQRVVIAIAIANDPDLLI
TH_3537|M.thermoresistible__bu ARARAVELLELVGINQPERRARSFPHELSGGERQRVVIAIAIANDPDLLI
MAB_0429|M.abscessus_ATCC_1997 ARDRAVELLDLVDMPEPAKRVKHYPHQLSGGQRQRAMIAQALALDPGLLI
MSMEG_6121|M.smegmatis_MC2_155 ARRKAVELMERVGIPQPESRLHDYPHQFSGGMRQRLLIAMAVALNPTVLI
Mvan_1021|M.vanbaalenii_PYR-1 AKRKAVDLMARVGIPQPESRLNSYPHQFSGGMRQRLLIAMAVALNPSVLI
*: :**:*: *.: :* * . :**::*** *** :** *:* :* :**
Mb1312c|M.bovis_AF2122/97 CDEPTTALDVTVQAQILDVLKAARDVTGAGVLIITHDLGVVAEFADRALV
Rv1281c|M.tuberculosis_H37Rv CDEPTTALDVTVQAQILDVLKAARDVTGAGVLIITHDLGVVAEFADRALV
MLBr_01122|M.leprae_Br4923 CDEPTTALDVTVQAQILEVLKTARDVTGAGVLIITHDLGVVTEFADQALV
MMAR_4138|M.marinum_M CDEPTTALDVTVQAQILDVLKTARDVTGAGVLIITHDLGVVAEFADRALV
MUL_4001|M.ulcerans_Agy99 CDEPTTALDVTVQAQILDVLKTARDVTGAGVLIITHDLGVVAEFADRALV
MAV_1431|M.avium_104 CDEPTTALDVTVQAQILEVLKTARDITGAGVLIITHDLGVVAELADRALV
Mflv_2259|M.gilvum_PYR-GCK CDEPTTALDVTVQAQILDVLRTARDVTGAGVLIITHDLGVVAEFADRALV
TH_3537|M.thermoresistible__bu CDEPTTALDVTVQAQILDVLKTARDVTGAGVLVITHDLGVVAEFADRALV
MAB_0429|M.abscessus_ATCC_1997 ADEPTTALDVTVQAEILDLMRDLRHRIDAGIILITHDMGVVADMADRIMV
MSMEG_6121|M.smegmatis_MC2_155 ADEPTTALDVTVQAQIMALLRDLRTEYHMAVVLITHDLALVVEEADRVAV
Mvan_1021|M.vanbaalenii_PYR-1 ADEPTTALDVTVQAQIMALLRDLRTEYRMAVVLITHDLALVAEEADRVAI
.*************:*: ::: * .:::****:.:*.: **: :
Mb1312c|M.bovis_AF2122/97 MYAGRVVESAGVNDLYRDRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPP
Rv1281c|M.tuberculosis_H37Rv MYAGRVVESAGVNDLYRDRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPP
MLBr_01122|M.leprae_Br4923 MYAGRVVESAQVSTLYRERQMPYTVGLLGSVPRLDATQGTRLVPIPGAPP
MMAR_4138|M.marinum_M MYAGRVVEKATVNDLYHNRRMPYTIGLLGSVPRLDATQGTRLVPIPGAPP
MUL_4001|M.ulcerans_Agy99 MYAGRVVEKATVNDLYHNRRMPYTIGLLGSVPRLDATQGTRLVPIPGAPP
MAV_1431|M.avium_104 MYAGRVVESAAVASLYRDRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPP
Mflv_2259|M.gilvum_PYR-GCK MYAGRAVEAAPVSDLYRNRRMPYTAGLLGSVPRLDATQGTRLVPIPGAPP
TH_3537|M.thermoresistible__bu MYAGRAVEVASVQQLYRDRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPP
MAB_0429|M.abscessus_ATCC_1997 MKDGEVVEQGDAEGIFHRAQQPYTRQLLASVPHLGATLHGRDESNP--PP
MSMEG_6121|M.smegmatis_MC2_155 MYAGQIVETGPVAEVFANPAHPYTKGLLDSVP-VSAVRGEALASIGGAPP
Mvan_1021|M.vanbaalenii_PYR-1 MYAGHIVETGTVAEVFAHPKHPYTQGLLSSVP-VNARRGDALTSIGGSPP
* *. ** . . :: *** ** *** :.* . **
Mb1312c|M.bovis_AF2122/97 SLAGLAPGCPFAPRCPLVIDECLTAEPELLDVATDHRAACIRTELVTGRS
Rv1281c|M.tuberculosis_H37Rv SLAGLAPGCPFAPRCPLVIDECLTAEPELLDVATDHRAACIRTELVTGRS
MLBr_01122|M.leprae_Br4923 SLAGLQQECPFAPRCPLVVDECRLREPELVEVRAGHRTACIRTDQVSGRS
MMAR_4138|M.marinum_M SLAGLDRGCPFAPRCPLVIDECRSDEPELIEVGQNHRAACIRTDQVNGRS
MUL_4001|M.ulcerans_Agy99 SPAGLDRGCPFAPRCPLVIDECRSDEPELIEVGQNHRAACIRTDQVNGRS
MAV_1431|M.avium_104 SLAGLDPGCPFAPRCPLAIDECRSQEPELLPVGPDHRAACIRTDQVDGRS
Mflv_2259|M.gilvum_PYR-GCK SVTNLPPGCPFTPRCPLAVDECSTAEPPLESVAPNHQVACIRNGDVAGRS
TH_3537|M.thermoresistible__bu AMTDLPPGCPFAPRCPLAIDDCRAAEPELLEITPAG--------------
MAB_0429|M.abscessus_ATCC_1997 T------------DLALSVEHAVIEYP-----------------------
MSMEG_6121|M.smegmatis_MC2_155 ELSAIPKGCVYQDRCPHVADICVTTRPVLE--------------------
Mvan_1021|M.vanbaalenii_PYR-1 DLHSIPQGCVYQARCPLAAEVCRTTRPALAPV------------------
. : . *
Mb1312c|M.bovis_AF2122/97 AADIYRVKT-EARPAALGDASVVVRVRHLVKTYRLAKGVVLRRAIGEVRA
Rv1281c|M.tuberculosis_H37Rv AADIYRVKT-EARPAALGDASVVVRVRHLVKTYRLAKGVVLRRAIGEVRA
MLBr_01122|M.leprae_Br4923 AADIYGINT-DTRTSATSDSSVVVRVRDLVKTYRLTKGVGLRRAIGEIRA
MMAR_4138|M.marinum_M AADIYGVQT-EATEPAPADSSVVVRVSDLVKTYPLTKGVLLRRSIGEVRA
MUL_4001|M.ulcerans_Agy99 AADIYGVQT-EATEPAPADSSVVVRVSDLVKTYPLTKGVLLRRSIGEVRA
MAV_1431|M.avium_104 AADIYGVRT-QPHPGEPANSPVVVRVRELSKTYRLTKG-VLRRSAGEVRA
Mflv_2259|M.gilvum_PYR-GCK AAEIYGVSTSPPRTEAASEDAVALRVEGLTKTFTLTKGLVFRRRIGEVRA
TH_3537|M.thermoresistible__bu ------------------------------------------PGHGEHRA
MAB_0429|M.abscessus_ATCC_1997 ------------------------------------------GKSGSFRA
MSMEG_6121|M.smegmatis_MC2_155 ---------------------------------------------GEHRR
Mvan_1021|M.vanbaalenii_PYR-1 ---------------------------------------------GGDRK
* *
Mb1312c|M.bovis_AF2122/97 VDGISLELRQGRTLGIVGESGSGKSTTLHEILELAAPQSGSIEVLGTDVA
Rv1281c|M.tuberculosis_H37Rv VDGISLELRQGRTLGIVGESGSGKSTTLHEILELAAPQSGSIEVLGTDVA
MLBr_01122|M.leprae_Br4923 VNGVSFELQQGRTLGIVGESGSGKSTTLHEILRLAVPQSGSIEVLGIDVA
MMAR_4138|M.marinum_M VDGVNFELRQGHTLGIVGESGSGKSTTLHQILELAAPQSGSIEVLGTDVT
MUL_4001|M.ulcerans_Agy99 VDGVSFELRQGHTLGIVGESGSGKSTTLHQILELAAPQSGSIEVLGTDVT
MAV_1431|M.avium_104 VDRISFQLRQGRTLGIVGESGSGKSTTLHEILELVAPQSGSIEVLGTDVA
Mflv_2259|M.gilvum_PYR-GCK VDGISFELQQGRTLGIVGESGSGKSTTLHQILELSPPQAGTIEVLGRDVA
TH_3537|M.thermoresistible__bu AX---XXLASAVALGTRRPGG-----------------------------
MAB_0429|M.abscessus_ATCC_1997 VDDVSFTIGRGEVVGLVGESGSGKSTIGRAAVGLLRVASGTICVAGQDIS
MSMEG_6121|M.smegmatis_MC2_155 AACHFSDRAAGGTGGEHHE-------------------------------
Mvan_1021|M.vanbaalenii_PYR-1 AACHFPEEVSPRMRGERTDV------------------------------
. *
Mb1312c|M.bovis_AF2122/97 TLGTAERRSLRRDIQVVFQDPVASLDPRLPVFDLIAEPLQAN-GFGKNET
Rv1281c|M.tuberculosis_H37Rv TLGTAERRSLRRDIQVVFQDPVASLDPRLPVFDLIAEPLQAN-GFGKNET
MLBr_01122|M.leprae_Br4923 TLNRASRRSMRRNIQVVFQDPVASLDPRLPVFELIAEPLHAN-GFSKNYT
MMAR_4138|M.marinum_M TLTASSRRALRRDIQVVFQDPVASLDPRLPISDLLAEPLQAN-GFNKTDT
MUL_4001|M.ulcerans_Agy99 TLTASSRRALRRDIQVVFQDPVASLDPRLPISDLLAEPLQAN-GFNKTDT
MAV_1431|M.avium_104 ALSPASRRSLRRDIQVVFQDPVASLDPRLPVFELLAEPLRAN-GFDKDHT
Mflv_2259|M.gilvum_PYR-GCK ALDRAGRRALRSDLQVVFQDPVASLDPRLPVFDILAEPLQDN-GFDKAAI
TH_3537|M.thermoresistible__bu --------------------------------------------------
MAB_0429|M.abscessus_ATCC_1997 TANRKQLRDIRSKVGVVFQDPGSSLNPRWPIGQSIAEPLTLHTDMDRTQR
MSMEG_6121|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1021|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 HARVAELLDIVGLRHGDASRYPAEFSGGQKQRIGIARALALQPKILALDE
Rv1281c|M.tuberculosis_H37Rv HARVAELLDIVGLRHGDASRYPAEFSGGQKQRIGIARALALQPKILALDE
MLBr_01122|M.leprae_Br4923 QMRVAELLDIVGLRRDDATRYPTEFSGGQKQRIGIARALALQPKILAFDE
MMAR_4138|M.marinum_M QDRVAELLDIVGLRRSDASRYPAEFSGGQKQRIGIARALALQPKILALDE
MUL_4001|M.ulcerans_Agy99 QDRVAELLDIVGLRRSDASRYPAEFSGGQKQRIGIARALALQPKILALDE
MAV_1431|M.avium_104 NARVAELLETVGLRRADAARYPAEFSGGQKQRIGIARALALQPKILALDE
Mflv_2259|M.gilvum_PYR-GCK RDRIAELLGVVGLRREDASRYPAEFSGGQKQRIGIARALALRPKILALDE
TH_3537|M.thermoresistible__bu --------------------------------------------------
MAB_0429|M.abscessus_ATCC_1997 EGRVKTLLEQVQLPAAMRNRFPHQLSGGQRQRVGIARALALEPTLLIADE
MSMEG_6121|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1021|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 PVSALDVSIQAGIINLLLDLQEQFGLSYLFVSHDLSVVKHLAHQVAVMLA
Rv1281c|M.tuberculosis_H37Rv PVSALDVSIQAGIINLLLDLQEQFGLSYLFVSHDLSVVKHLAHQVAVMLA
MLBr_01122|M.leprae_Br4923 PVSALDVSIQAGIINLLLDLQDRLGLSYLFVSHDLSVIKHLAHQVAVMLA
MMAR_4138|M.marinum_M PVSALDVSIQAGIINLLLDLQARFKLSYLFVSHDLSVVKHLAHSVVVMFA
MUL_4001|M.ulcerans_Agy99 PVSALDVSIQAGIINLLLDLQAGFKLSYLFVSHDLSVVKHLANSVVVMFA
MAV_1431|M.avium_104 PVSALDVSIQAGIINLLLDLQAQFQLSYLFVSHDLSVVKHLAHDVAVMYA
Mflv_2259|M.gilvum_PYR-GCK PVSALDVSIQAGIVNLLLDLQERFGLAYLFVSHDLSVVRHLAHRVAVMNK
TH_3537|M.thermoresistible__bu --------------------------------------------------
MAB_0429|M.abscessus_ATCC_1997 PTSALDVSVQATVLDLFAELQREHGFACLFISHDLAVVELVASRIAVLNR
MSMEG_6121|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1021|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 GTVVEQGDSEEVFGNPKHEYTRRLLGAVPQPDPARRG----------
Rv1281c|M.tuberculosis_H37Rv GTVVEQGDSEEVFGNPKHEYTRRLLGAVPQPDPARRG----------
MLBr_01122|M.leprae_Br4923 GTIVEQGDSHDVFRNPQHDYTRRLLGAIPRPEVG-------------
MMAR_4138|M.marinum_M GSIVEQGNSQEVFSNPQHEYTQRLLGAVPQPIPGNAD----------
MUL_4001|M.ulcerans_Agy99 GSIVEQGNSQEVFSNPQHEYTQRLLGAVPQPIPGNAD----------
MAV_1431|M.avium_104 GSIVEQGDSSQVFGNPQHEYTRRLLDAVPQPNPGSRG----------
Mflv_2259|M.gilvum_PYR-GCK GVIVEQGDSDQVFGSPRHDYTRRLLDAVPRPQADRR-----------
TH_3537|M.thermoresistible__bu -----------------------------------------------
MAB_0429|M.abscessus_ATCC_1997 GRLAEFGSDTQVLTAPKDDYTKRLLAAVPVPDPEQQRIRREERQALR
MSMEG_6121|M.smegmatis_MC2_155 -----------------------------------------------
Mvan_1021|M.vanbaalenii_PYR-1 -----------------------------------------------