For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VAAPAVPSVPTAPVSGAPVAPSASSAPSAGGALVSPVERAASKAVAGQAGASSSTMAGASALSATAGATA GAVSARAAEQQRLQRIVDAVARQEPRISWAAGLRDDGTTTLLVTDLAGGWIPPHVRLPANVTLLEPTARR RDADVIDLLGAVVAVAAHESNTYVAEPGPDAPALTGDRSARSAIPKVDEFGPTLVEAVRRRDSLPRIAQA IALPAVRKTGVLENEAELLHGCITAVKESVLKAYPSHELTAVGDWMLLAAIEALIDEQDYLANYHLAWYA VTTRRGGSRGFAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3928c | - | - | 100% (293) | hypothetical protein Mb3928c |
| M. bovis AF2122 / 97 | Mb2108 | - | 1e-87 | 58.95% (285) | hypothetical protein Mb2108 |
| M. bovis AF2122 / 97 | Mb0030 | - | 3e-27 | 33.88% (245) | hypothetical protein Mb0030 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3899c | - | 1e-162 | 100.00% (293) | hypothetical protein Rv3899c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3066 | - | 5e-92 | 63.44% (279) | hypothetical protein MMAR_3066 |
| M. avium 104 | MAV_5288 | - | 1e-121 | 73.61% (288) | hypothetical protein MAV_5288 |
| M. smegmatis MC2 155 | MSMEG_0805 | - | 9e-06 | 30.33% (122) | hypothetical protein MSMEG_0805 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0047 | - | 3e-33 | 34.08% (267) | hypothetical protein MUL_0047 |
| M. vanbaalenii PYR-1 | Mvan_3258 | - | 1e-05 | 28.99% (138) | hypothetical protein Mvan_3258 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3928c|M.bovis_AF2122/97 --------------------------------------------------
Rv3899c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_5288|M.avium_104 --------------------------------------------------
MMAR_3066|M.marinum_M MGADLPPGRWSAWLVGPWWPAPPGSPAAGVSYWRQAGEIKQNEARDLQIE
MUL_0047|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3258|M.vanbaalenii_PYR-1 ----MPAVGGSAGSYGRLIVTPDMEPPDAGHWDAQEQTYRVGATTWDGIH
MSMEG_0805|M.smegmatis_MC2_155 --------------------------------------------------
Mb3928c|M.bovis_AF2122/97 --------------------------------------------------
Rv3899c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_5288|M.avium_104 --------------------------------------------------
MMAR_3066|M.marinum_M RSRLAVNQGRTADDLMGRYWRGEQSLSATGEQCDTKSVQSGRVVDAVNNL
MUL_0047|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3258|M.vanbaalenii_PYR-1 QKIVTDNAEFRDAADSQGFDEAHRAGAVLAEEAKTIAEWHDKCANKCADI
MSMEG_0805|M.smegmatis_MC2_155 --------------------------------------------------
Mb3928c|M.bovis_AF2122/97 --------------------------------------------------
Rv3899c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_5288|M.avium_104 --------------------------------------------------
MMAR_3066|M.marinum_M RDRLRDIAHSGNGEIDRILSEKRPIEAIVAAVNAVIARANTDAANAGAAA
MUL_0047|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3258|M.vanbaalenii_PYR-1 ATVLRDTR-AGQEQLVREADAKIASAKLPGEAEALVTQYHGIARYQTEAG
MSMEG_0805|M.smegmatis_MC2_155 --------------------------------------------------
Mb3928c|M.bovis_AF2122/97 --------------------------------------------------
Rv3899c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_5288|M.avium_104 --------------------------------------------------
MMAR_3066|M.marinum_M MSNIIDATQRVLDTTIGGNARTWLREHGVDLDNAPPSRPITALDLNAQLA
MUL_0047|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3258|M.vanbaalenii_PYR-1 VTAAMASHTAFKASTENTRALDLLTKWG-DAPTAPPVQPVDHTSPGIEQD
MSMEG_0805|M.smegmatis_MC2_155 --------------------------------------------------
Mb3928c|M.bovis_AF2122/97 --------------------------------------------------
Rv3899c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_5288|M.avium_104 --------------------------------------------------
MMAR_3066|M.marinum_M APSTLSAYASAQATTTSGPYAAAPTEPAAYGGTQPLNISLPDVAPTDPPA
MUL_0047|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3258|M.vanbaalenii_PYR-1 ENPYSDTEKREAGADAPKPVDDAPTDPAGTSTTQPG---------VSPGS
MSMEG_0805|M.smegmatis_MC2_155 --------------------------------------------------
Mb3928c|M.bovis_AF2122/97 --------------------------------------------------
Rv3899c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_5288|M.avium_104 -----------------------------------------MAPSGLGLG
MMAR_3066|M.marinum_M TLAYGGTQVPISAPRGNMPPPLAPPSPGAPAVGVGGPSIPGVSTPAASAP
MUL_0047|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3258|M.vanbaalenii_PYR-1 KSAAGDESIKAATGPVTQPTPGVTSSPAASALG----GAGMPSMGGIGGG
MSMEG_0805|M.smegmatis_MC2_155 --------------------------------------------------
Mb3928c|M.bovis_AF2122/97 --------------------------------------------------
Rv3899c|M.tuberculosis_H37Rv --------------MVTGQPAAAGAHSLSEGAMTAMQSGSVPPPQATPPI
MAV_5288|M.avium_104 PGGQPNLAQSFASGLATGQATGPGGQAFSANALQAMETGAPQTPAGTPPV
MMAR_3066|M.marinum_M PLSPQSLAQSFTNGMSTGAPAAAGANSISAGAMTAATE-PPPPTTAPPAA
MUL_0047|M.ulcerans_Agy99 -------------------MAIFGRRTARQRLRKAAQESLVIPAFSSP--
Mvan_3258|M.vanbaalenii_PYR-1 GMGSGGGIPKMPGGLGSGGMPGMGSNPLSGGVGQMPGAASGLPNPGAVPG
MSMEG_0805|M.smegmatis_MC2_155 -------------------------MPLGPRRLRHQRRPPRVAPTAAPP-
Mb3928c|M.bovis_AF2122/97 --------------------------------------------------
Rv3899c|M.tuberculosis_H37Rv TTPPVVSAPTMAAGIEATHG-----PVDTPANTSGAPPASTGTTGPVAPT
MAV_5288|M.avium_104 AP----TVPSAGAFIAATP------PVDAPPAAAPAPSAAGG-AAPVAPA
MMAR_3066|M.marinum_M PLIPPSTVPATGAGFTHVPDAGLGAAPTSPPPVAPPTSDMTGGVTTVAP-
MUL_0047|M.ulcerans_Agy99 --------------------------PDCTPWVIGGLWPTELSRDAPETA
Mvan_3258|M.vanbaalenii_PYR-1 AGSASPLSSAFNQGMATTAGMGGGIPSAPPPAPASPSPALSAGGGHAAPP
MSMEG_0805|M.smegmatis_MC2_155 ---------------------------------PPPVAPTQAGGAQVAPI
Mb3928c|M.bovis_AF2122/97 -------------------------------------MAAPAVPSVPTAP
Rv3899c|M.tuberculosis_H37Rv VVTAGPVAAPAAPVVGGSAVPAGPLPAYGSDL-RPPVVAAPAVPSVPTAP
MAV_5288|M.avium_104 VMTGGSWSSAAT---GGPSVPSGSLPAYGSDL-RPPVLAAPSVPSAPTGP
MMAR_3066|M.marinum_M MMAGGPVTGSVAP---AVGAPAGPLPAYGSDL-RPPTVAPPAVPSAPTGP
MUL_0047|M.ulcerans_Agy99 TLAEYLEADLQRIADSANEELASLRHAVMLDS-DRRAAEARVIDEARARA
Mvan_3258|M.vanbaalenii_PYR-1 VSAAPGGGVSPAGAQAGMVSPATPAAAAPTGAGIGGGGAPMMLPPGSMGP
MSMEG_0805|M.smegmatis_MC2_155 PVSAAR----------AEREAAAAARRSGVEPLEIARRVAAVLNAGPREP
. : .
Mb3928c|M.bovis_AF2122/97 ----VSGAPVAPSASSAPSAGGALVSPVER-AASKAVAGQAGASSSTMAG
Rv3899c|M.tuberculosis_H37Rv ----VSGAPVAPSASSAPSAGGALVSPVER-AASKAVAGQAGASSSTMAG
MAV_5288|M.avium_104 ----VSGAPVAPSPASSPSAGGTLVSPVER-SAASAAAGQAGAGSSTLAN
MMAR_3066|M.marinum_M ----VSGAPVA-SPSSSPSAGGSMVSPVAKSSAHDAAQAQTTSGPTSMAG
MUL_0047|M.ulcerans_Agy99 ----VQRIESARNQLREGASTEPPVAPRDIADPNAGEPGSQPQPPMAGRP
Mvan_3258|M.vanbaalenii_PYR-1 ----PAGAPPPAPTVPAGTVGSTNAPAAPAPSAASAAAGPTLIPASVVAA
MSMEG_0805|M.smegmatis_MC2_155 KFMWLTGLTTDGTIVVANNYGLGYISPWVKLPAPVKFAFADESIPIAERA
.. . .
Mb3928c|M.bovis_AF2122/97 ASALSATAGATAGAVSARAAEQQRLQRIVDAVARQEPRISWAAGLRDDGT
Rv3899c|M.tuberculosis_H37Rv ASALSATAGATAGAVSARAAEQQRLQRIVDAVARQEPRISWAAGLRDDGT
MAV_5288|M.avium_104 ASAVSAAAGATAGAASSRAAEQQRLQRLVDAVARQEPRLSWAAGLRDDGI
MMAR_3066|M.marinum_M ATAA-ATTGAVTGDSAKRSAEQQRLRRIVDAVARQEPGLSWAAGLRDDGR
MUL_0047|M.ulcerans_Agy99 DAVDAARAAARAPAPAVPESDDQRLRRLLMFVARQEPRLNWAIGRQSEG-
Mvan_3258|M.vanbaalenii_PYR-1 GQTAAARERRESADAAAAKELVWKLQHAAYVALNPAAGWAVGVFRSPSGT
MSMEG_0805|M.smegmatis_MC2_155 KWVTFPIAALQG-----WAESHHTALRAVIAMEDQFEGFDSGCAEIKLQP
. . : .
Mb3928c|M.bovis_AF2122/97 TTLLVTDLAGGWIPPHVRLPANVTLLEPTARRRDADVIDLLG--------
Rv3899c|M.tuberculosis_H37Rv TTLLVTDLAGGWIPPHVRLPANVTLLEPTARRRDADVIDLLG--------
MAV_5288|M.avium_104 TTLLVTDLASGWIPPHVRLPAHVTLLEPAARRHDANVVDLLG--------
MMAR_3066|M.marinum_M TTLLVTDLAGGWIPPHVRLPSHVTLLEPATRRSDIGAADLLG--------
MUL_0047|M.ulcerans_Agy99 -TVLVTDVAHGWIPPGIALPQGVRLLPP--KRRSGRLAALVD--------
Mvan_3258|M.vanbaalenii_PYR-1 ETVITSNDGSSYIPAGVFVPRSVRVLATDPLVDDSFRQRWFGWGDPARVL
MSMEG_0805|M.smegmatis_MC2_155 DDIPTAGKMEGRSRLEVLAPDVAIRLAS---VPDTALADLLP--------
: .:. . : * . * . . .
Mb3928c|M.bovis_AF2122/97 ------------AVVAVAAHESNTYVAEPGPDAPALTGDRSARSAIPKVD
Rv3899c|M.tuberculosis_H37Rv ------------AVVAVAAHESNTYVAEPGPDAPALTGDRSARSAIPKVD
MAV_5288|M.avium_104 ------------AVTVAAAHHANTYVAEPGSDEPTLSGDRPARSAAPQID
MMAR_3066|M.marinum_M ------------AVTISAVHQPHGYIGEPGRDAPKLAGDRAAR-IAPEID
MUL_0047|M.ulcerans_Agy99 ------------AATGSLSYSPGDPLPWVDEDTATRSSVRPRE--LPMAD
Mvan_3258|M.vanbaalenii_PYR-1 VEYAQLRAQWGWKLVAAATTAGVSVLRDAGVEHPPSCSGDTNPLLQQGVD
MSMEG_0805|M.smegmatis_MC2_155 --------------------PPPADPEPPEDRRMNLLMEVFRPLLSSDSG
.
Mb3928c|M.bovis_AF2122/97 EFGPTLVEAVRRRDSLPR----------------------------IAQA
Rv3899c|M.tuberculosis_H37Rv EFGPTLVEAVRRRDSLPR----------------------------IAQA
MAV_5288|M.avium_104 ELGPTLVDAVRRRDGLPR----------------------------IAQA
MMAR_3066|M.marinum_M ELGPTLAEHVRRRDGLPR----------------------------VAQV
MUL_0047|M.ulcerans_Agy99 NVARELCDATRSRVGLPR----------------------------MAHV
Mvan_3258|M.vanbaalenii_PYR-1 VPAPVLDDMHIHRLAVLWPEVYPRLLRIMDADPLCQDRIVSAVTAAMINA
MSMEG_0805|M.smegmatis_MC2_155 RIPLQLKAMAEFADHMQK---------------------------MALHS
* : :
Mb3928c|M.bovis_AF2122/97 IALPAVRKTGVLENEAELLHGCITAVKESVLKAYPSHELTAVGDWMLLAA
Rv3899c|M.tuberculosis_H37Rv IALPAVRKTGVLENEAELLHGCITAVKESVLKAYPSHELTAVGDWMLLAA
MAV_5288|M.avium_104 VAAPAVRKTGVLESEIRMLRECTAEIQHAVLTAYPHHDPAAVGDWMLLAA
MMAR_3066|M.marinum_M VAVAAARNYGVPDNEAELLRDRASDIHRSVLAAYPHHDLAEATDWMLLAA
MUL_0047|M.ulcerans_Agy99 LAKAADAGTAVVEDEIDLLRVHLDTARHQIVAHYPSIDGEVLLNWMLLAA
Mvan_3258|M.vanbaalenii_PYR-1 ATTQAQVIDGGIDEALRLVWAVRGSDREPTVQQWADYDKAAKALNVMTAM
MSMEG_0805|M.smegmatis_MC2_155 AYTAADAEALRIDTEDAIYWQHVGVLSRDALGTMPEGSQSSERHRSRKWR
* : : . : . .
Mb3928c|M.bovis_AF2122/97 IEALIDEQD-----------YLANYHLAWYAVTTRRGGSRGFAA------
Rv3899c|M.tuberculosis_H37Rv IEALIDEQD-----------YLANYHLAWYAVTTRRGGSRGFAA------
MAV_5288|M.avium_104 IQALIDGHE-----------YLAHYHLAWFQAINHRAGS-----------
MMAR_3066|M.marinum_M IDALIDGNR-----------TAANYHLAWAMAAMSMRRPT----------
MUL_0047|M.ulcerans_Agy99 TASSVNGDA-----------VTANYHLAWFRELKA---------------
Mvan_3258|M.vanbaalenii_PYR-1 RRPAFATNTGAVADPSDTTEFLADYRAHWLVARTAEHIGGWSRRPLPLPD
MSMEG_0805|M.smegmatis_MC2_155 RRVTRHAFD-----------LSGPAESTRYRGCNAT--------------
. .
Mb3928c|M.bovis_AF2122/97 ----------------------------------
Rv3899c|M.tuberculosis_H37Rv ----------------------------------
MAV_5288|M.avium_104 ----------------------------------
MMAR_3066|M.marinum_M ----------------------------------
MUL_0047|M.ulcerans_Agy99 ----------------------------------
Mvan_3258|M.vanbaalenii_PYR-1 MCYAAAATGDPDLRDMIVKALVSVEEDLQYEAPR
MSMEG_0805|M.smegmatis_MC2_155 ----------------------------------