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MPLGPRRLRHQRRPPRVAPTAAPPPPPVAPTQAGGAQVAPIPVSAARAEREAAAAARRSGVEPLEIARRV AAVLNAGPREPKFMWLTGLTTDGTIVVANNYGLGYISPWVKLPAPVKFAFADESIPIAERAKWVTFPIAA LQGWAESHHTALRAVIAMEDQFEGFDSGCAEIKLQPDDIPTAGKMEGRSRLEVLAPDVAIRLASVPDTAL ADLLPPPPADPEPPEDRRMNLLMEVFRPLLSSDSGRIPLQLKAMAEFADHMQKMALHSAYTAADAEALRI DTEDAIYWQHVGVLSRDALGTMPEGSQSSERHRSRKWRRRVTRHAFDLSGPAESTRYRGCNAT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_0805 | - | - | 100% (343) | hypothetical protein MSMEG_0805 |
M. smegmatis MC2 155 | MSMEG_0071 | - | 2e-81 | 54.69% (309) | hypothetical protein MSMEG_0071 |
M. smegmatis MC2 155 | MSMEG_0075 | - | 5e-24 | 49.57% (115) | hypothetical protein MSMEG_0075 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3909c | - | 2e-65 | 46.44% (295) | hypothetical protein Mb3909c |
M. gilvum PYR-GCK | Mflv_0760 | - | 2e-74 | 47.67% (300) | hypothetical protein Mflv_0760 |
M. tuberculosis H37Rv | Rv3879c | - | 2e-65 | 46.44% (295) | hypothetical protein Rv3879c |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_5455 | - | 1e-64 | 45.18% (301) | hypothetical protein MMAR_5455 |
M. avium 104 | MAV_5288 | - | 2e-06 | 31.85% (135) | hypothetical protein MAV_5288 |
M. thermoresistible (build 8) | TH_2928 | - | 2e-61 | 50.45% (222) | PUTATIVE conserved hypothetical alanine and proline rich |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_0085 | - | 5e-77 | 49.69% (320) | hypothetical protein Mvan_0085 |
CLUSTAL 2.0.9 multiple sequence alignment Mb3909c|M.bovis_AF2122/97 MSITRPTGSYARQMLDPGGWVEADEDTFYDRAQEYSQVLQRVTDVLDTCR Rv3879c|M.tuberculosis_H37Rv MSITRPTGSYARQMLDPGGWVEADEDTFYDRAQEYSQVLQRVTDVLDTCR MMAR_5455|M.marinum_M MGIPRPTGEYAGRMLEAGGWPDADEDIHYDRAREYNRVLHLFTDVMDACR Mflv_0760|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0085|M.vanbaalenii_PYR-1 MGISKNVGEYVEEMTEPAGWPHVDEDHLYTRASGFVDKVTQLIAVRDSWQ TH_2928|M.thermoresistible__bu -------------------------------------------------- MSMEG_0805|M.smegmatis_MC2_155 -------------------------------------------------- MAV_5288|M.avium_104 -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 QQKGHVFEGGLWSGGAANAANGALGANINQLMTLQDYLATVITWHRHIAG Rv3879c|M.tuberculosis_H37Rv QQKGHVFEGGLWSGGAANAANGALGANINQLMTLQDYLATVITWHRHIAG MMAR_5455|M.marinum_M HQQVEVFDGGVWSGGAASAANGALGGNLEQMSTLQDYLATVITWHQHVAG Mflv_0760|M.gilvum_PYR-GCK -----MFVDGVWTGGAADAAKSAVENRLQQMHSLIAQLEKAIAWYSMIAR Mvan_0085|M.vanbaalenii_PYR-1 QQQARLFGGGAWSGAAANAAETAIQARVSEMISLINHLEKAIAWYTMTAR TH_2928|M.thermoresistible__bu -------------------------------------------------- MSMEG_0805|M.smegmatis_MC2_155 -------------------------------------------------- MAV_5288|M.avium_104 -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 LIEQAKSDIGNNVDGAQREIDILENDPSLDADERHTAINSLVTATHGANV Rv3879c|M.tuberculosis_H37Rv LIEQAKSDIGNNVDGAQREIDILENDPSLDADERHTAINSLVTATHGANV MMAR_5455|M.marinum_M LIAEAKANIDNNVDGAHREIRVLEGNADLDPEERKAAIASLIRSAHEANS Mflv_0760|M.gilvum_PYR-GCK VVVDAKLAVNDNLLAAQDYFSVIRKSPELEPGEKEALIQNWVRSQNVVNT Mvan_0085|M.vanbaalenii_PYR-1 TIAQTKATINQNLETSYSFIASIRASPELDEVEKDGIIQSWVQSQRAVNT TH_2928|M.thermoresistible__bu -------------------------------------------------- MSMEG_0805|M.smegmatis_MC2_155 -------------------------------------------------- MAV_5288|M.avium_104 -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 SLVAETAERVLESKNWKPPKNALEDLLQQKSPPPPDVPTLVVPSPGTPG- Rv3879c|M.tuberculosis_H37Rv SLVAETAERVLESKNWKPPKNALEDLLQQKSPPPPDVPTLVVPSPGTPG- MMAR_5455|M.marinum_M GLVAEAAEQVLASRNWKPPHNALKDLLHQVTPPAPGIPSVTVPTPGQPAP Mflv_0760|M.gilvum_PYR-GCK AIILGAMAKVPAFTTWQPPPQPVRVPHSP----DTSAAS---VPKSSLD- Mvan_0085|M.vanbaalenii_PYR-1 VTVLTAAGDVAAFDSWQPPPSPQRIPATLSPPESVSAPSGPEPPKQNVG- TH_2928|M.thermoresistible__bu -------------------------------------------------- MSMEG_0805|M.smegmatis_MC2_155 -------------------------------------------------- MAV_5288|M.avium_104 -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 -TPGTPGTPITPGTPITPGTPITPGTPITP--GTPITPIPGAPVTPITP- Rv3879c|M.tuberculosis_H37Rv -TPGTP---------------ITPGTPITP--GTPITPIPGAPVTPITP- MMAR_5455|M.marinum_M RPPGPKPFEPTPVNPHKPVTPGGPGTPVNPKPGAPVVPTPGGPTHPVTPG Mflv_0760|M.gilvum_PYR-GCK --------------------HFGPVRLTSPRVVLASNRVGPKEAPELAAN Mvan_0085|M.vanbaalenii_PYR-1 --------------------YFGPTRPPAAEPRGGSAGLSAKAANDAYMA TH_2928|M.thermoresistible__bu -------------------------------------------------- MSMEG_0805|M.smegmatis_MC2_155 -------------------------------------------------- MAV_5288|M.avium_104 -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 ------------TPGTPVTP---VTPGKPVTPVTPVKPGTPGEP-TPITP Rv3879c|M.tuberculosis_H37Rv ------------TPGTPVTP---VTPGKPVTPVTPVKPGTPGEP-TPITP MMAR_5455|M.marinum_M IPGTPGTPGIPGIPGTPITPGTPITPGKPVTPVTPGKP-KPGKPDTPVLP Mflv_0760|M.gilvum_PYR-GCK -----------------------ANPHGPRSAVTPPHPATATSPTTSSGG Mvan_0085|M.vanbaalenii_PYR-1 -----------------------QGPSASADQPVPISQSSGGGSPGSPGG TH_2928|M.thermoresistible__bu -------------------------------------------------- MSMEG_0805|M.smegmatis_MC2_155 -------------------------------------------------- MAV_5288|M.avium_104 -------------------------------------------MAPSGLG Mb3909c|M.bovis_AF2122/97 VTPPVAPATPATPATPVTPAPAPHPQPAPAPAPS----PGPQP------- Rv3879c|M.tuberculosis_H37Rv VTPPVAPATPATPATPVTPAPAPHPQPAPAPAPS----PGPQP------- MMAR_5455|M.marinum_M VEPTPAPAPAPAPAPAPAPAPAPAPAPAPAPQPAPAPGPGPQPGPADPGA Mflv_0760|M.gilvum_PYR-GCK VSTANSPS-AASASTPSASSPMSSSGGPPSTGGASSGSPSASTSP----A Mvan_0085|M.vanbaalenii_PYR-1 LGSPGSPSSSTSGSSPISTSGGSSSGSGASSSGSGSGSGGSSSAA----A TH_2928|M.thermoresistible__bu -------------------------------------------------- MSMEG_0805|M.smegmatis_MC2_155 -------------------------------------------------- MAV_5288|M.avium_104 LGPGGQPNLAQSFASGLATGQATGPG------------------------ Mb3909c|M.bovis_AF2122/97 -VTPATPGPSGPATPGTPGGEPAPHVKPAALAEQPGVPGQHAGGGTQSGP Rv3879c|M.tuberculosis_H37Rv -VTPATPGPSGPATPGTPGGEPAPHVKPAALAEQPGVPGQHAGGGTQSGP MMAR_5455|M.marinum_M SPQPAPSQPGSPSTPGQPSTDPA-HVKPAAATETSTAPSTQPSG--PSGP Mflv_0760|M.gilvum_PYR-GCK SGS---PSTASPTTSGAAGAQPS-NASPAGAAKAQPSPIQQVFNQSAP-L Mvan_0085|M.vanbaalenii_PYR-1 SSSGTSPTSGGQSATGAAGGQPT-AASPASAAKAQPSPMQQMVNQAPPPL TH_2928|M.thermoresistible__bu -------------------------------------------------- MSMEG_0805|M.smegmatis_MC2_155 -------------------------------------------------- MAV_5288|M.avium_104 ---------GQAFSANALQAMETGAPQTPAGTPPVAPTVPSAGAFIAATP Mb3909c|M.bovis_AF2122/97 AHADESAAS-VTPAAASGVPG-ARAAAAAPSGTAVGAGARSSVGTAAASG Rv3879c|M.tuberculosis_H37Rv AHADESAAS-VTPAAASGVPG-ARAAAAAPSGTAVGAGARSSVGTAAASG MMAR_5455|M.marinum_M AHGDDSSGGGAAAPAASAMPGGGRGVSAGSSSGLSSAGASSSTSQSAASG Mflv_0760|M.gilvum_PYR-GCK ASSAPAQSP-AAPPS-SAPAPTTPAGAAPTAGTGAGGGLSTSGGPAPVAG Mvan_0085|M.vanbaalenii_PYR-1 ASSAPATSP-APAPAPSQPAAAPSAAAGAGPSSGGVGGISASAGSAPVGA TH_2928|M.thermoresistible__bu -------------------------------------------------- MSMEG_0805|M.smegmatis_MC2_155 --------------------------------------MPLGPRRLRHQR MAV_5288|M.avium_104 PVDAPPAAAPAPSAAGGAAPVAPAVMTGGSWSSAATGGPSVPSGSLPAYG Mb3909c|M.bovis_AF2122/97 AGSHAATGRAPVATSDKAAAPST-RAASARTAPPARP-PSTDHIDKPDRS Rv3879c|M.tuberculosis_H37Rv AGSHAATGRAPVATSDKAAAPST-RAASARTAPPARP-PSTDHIDKPDRS MMAR_5455|M.marinum_M AGSRAASGRAPVESGGRGPNTAAPRPAAARTASPTRPAPERPKPDEKEKS Mflv_0760|M.gilvum_PYR-GCK APAGAAPPAAPPVPLAPPTSPAPPAP-PPTGAPGAAPAG-LGAGVAPMSA Mvan_0085|M.vanbaalenii_PYR-1 APPSGAPP-APPVPLGPPTSPAPPGPVPPTGTPGTAPGGAMGPGVAPMST TH_2928|M.thermoresistible__bu -------------------------------------------------- MSMEG_0805|M.smegmatis_MC2_155 RPPRVAPTAAPPPPPVAPT------------------------------- MAV_5288|M.avium_104 SDLRPPVLAAPSVP-SAPTGPVSGAPVAPSPASSPSAGGTLVSPVERSAA Mb3909c|M.bovis_AF2122/97 ESADDGTPVSMIPVSAARAARDAATAAASA----RQRGRGDALRLARRIA Rv3879c|M.tuberculosis_H37Rv ESADDGTPVSMIPVSAARAARDAATAAASA----RQRGRGDALRLARRIA MMAR_5455|M.marinum_M EAPDAVTPSPMVPVSAARAARDAIASAS------RRSQKKDPLRLARRIA Mflv_0760|M.gilvum_PYR-GCK TSSSSGAAAAPIPVSQARAERDAVLAASTAGALRRKNNGSDPLQRARHIG Mvan_0085|M.vanbaalenii_PYR-1 TGTAGGAAPAPIPVSTARAERDAIAAASTAGALRRKTNGADPLQQARHIA TH_2928|M.thermoresistible__bu ---------------------------------MRTDXXXPPVQWN---- MSMEG_0805|M.smegmatis_MC2_155 --QAGGAQVAPIPVSAARAEREAAAAA--------RRSGVEPLEIARRVA MAV_5288|M.avium_104 SAAAGQAGAGSSTLANASAVSAAAGATAG----AASSRAAEQQRLQRLVD . Mb3909c|M.bovis_AF2122/97 AALNASDN-NAGDYGFFWITAVTTDG-SIVVANSYGLAYIPDGMELPNKV Rv3879c|M.tuberculosis_H37Rv AALNASDN-NAGDYGFFWITAVTTDG-SIVVANSYGLAYIPDGMELPNKV MMAR_5455|M.marinum_M AALNAPDTYNKGDYGFFWITAVTTDG-DIVVANSYGLAYIPENVELPHKV Mflv_0760|M.gilvum_PYR-GCK AALNVGVK----DFGFFWVTAVTTDG-TIVVANSYGIGYIPDGVRLPENV Mvan_0085|M.vanbaalenii_PYR-1 AALNVGIM----DFGFFWVTGVTMEG-TIVVANSYGLAYIPAGVALPDQV TH_2928|M.thermoresistible__bu ---------------FMWATGVTADG-GIVVANSYGLAFIPDGVNLPEQV MSMEG_0805|M.smegmatis_MC2_155 AVLNAGPR----EPKFMWLTGLTTDG-TIVVANNYGLGYISPWVKLPAPV MAV_5288|M.avium_104 AVARQEPR-------LSWAAGLRDDGITTLLVTDLASGWIPPHVRLPAHV : * :.: :* ::... . .:*. : ** * Mb3909c|M.bovis_AF2122/97 YLASADHAIPVDEIARCATYPVLAVQAWAAFHDMTLRAVIGTAEQLASSD Rv3879c|M.tuberculosis_H37Rv YLASADHAIPVDEIARCATYPVLAVQAWAAFHDMTLRAVIGTAEQLASSD MMAR_5455|M.marinum_M YMASADHAIPADEQARFATYPVLAVQGWAAFHDLKLRAVIGTAEQLANSD Mflv_0760|M.gilvum_PYR-GCK RMASADDTIPADERAKWATYPILAVQGWAQHHELQLRAVVATEEQFANFD Mvan_0085|M.vanbaalenii_PYR-1 RMATADESIPAGERAKWATYPILAVQGWAQHHNQQLRAVVATEEQFANFD TH_2928|M.thermoresistible__bu KMVTADESVPPTERARWASYPYLALQGWAQHTGATLQAVIGTDEQLRGID MSMEG_0805|M.smegmatis_MC2_155 KFAFADESIPIAERAKWVTFPIAALQGWAESHHTALRAVIAMEDQFEGFD MAV_5288|M.avium_104 TLLEP----------------------AARRHDANVVDLLGAVTVAAAHH : . * : ::. . Mb3909c|M.bovis_AF2122/97 PGVAKIVLEPDDIPESGKMTGRSRLEVVDPSAAAQLADTTDQRLLDLLPP Rv3879c|M.tuberculosis_H37Rv PGVAKIVLEPDDIPESGKMTGRSRLEVVDPSAAAQLADTTDQRLLDLLPP MMAR_5455|M.marinum_M AGAAKIILEADDIPESGKMTGRPRLEVVDPSAAAQLAETEDLRLLELLPP Mflv_0760|M.gilvum_PYR-GCK PGVAKIILTAEDIPDDGTMSGRTRLEVISPTAAQQLSAVGDFGLNDLLPP Mvan_0085|M.vanbaalenii_PYR-1 PGVAKIILTQDDIPESGQMQGRSRLEVIAPEAAQRLSAVSDFGLNDLLPP TH_2928|M.thermoresistible__bu PGARKVLIDEADIPQNGTMQGRSRLEVISPEAAARLAAMSDATLPDLLPP MSMEG_0805|M.smegmatis_MC2_155 SGCAEIKLQPDDIPTAGKMEGRSRLEVLAPDVAIRLASVPDTALADLLPP MAV_5288|M.avium_104 ANTYVAEPGSDEPTLSGDRPARSAAPQIDELGPTLVDAVRRR---DGLPR .. : . * .*. : . : : ** Mb3909c|M.bovis_AF2122/97 APVDVNPPGDERHMLWFELMKPMTSTATGREAAHLRAFRAYAAHSQEIAL Rv3879c|M.tuberculosis_H37Rv APVDVNPPGDERHMLWFELMKPMTSTATGREAAHLRAFRAYAAHSQEIAL MMAR_5455|M.marinum_M APADANPPDDERHMFWFDLMKPMTSNATGREVAHLRAFRAYAEHCQEIAL Mflv_0760|M.gilvum_PYR-GCK APTDLEPPADQTATLWFEVAKPLMSTNPQRSAAHLQAFITYANHAQELAV Mvan_0085|M.vanbaalenii_PYR-1 ATADLEPPADDSARLWFEVAKPLMSTNPQRSGPHLQAFVAYAKHAQELAL TH_2928|M.thermoresistible__bu SPVDDTPPEDRSKKLWFDMIKPLMRSGSGREADHLKGFVAYADHRQELAL MSMEG_0805|M.smegmatis_MC2_155 PPADPEPPEDRRMNLLMEVFRPLLSSDSGRIPLQLKAMAEFADHMQKMAL MAV_5288|M.avium_104 IAQAVAAPAVRKTGVLESEIRMLRECTAEIQHAVLTAYPHHDPAAVGDWM . .* . . : : . * . . : Mb3909c|M.bovis_AF2122/97 HQAHTATDAAVQRVAVADWLYWQYVTGLLDRALAAAS------------- Rv3879c|M.tuberculosis_H37Rv HQAHTATDAAVQRVAVADWLYWQYVTGLLDRALAAAC------------- MMAR_5455|M.marinum_M HQAYSAADAEAQRPAVADWLYWRYVAGLLANALADAS------------- Mflv_0760|M.gilvum_PYR-GCK YRAHTAAEPADQRLAIADWVYWQHLAVIMNDAVNADASA----------- Mvan_0085|M.vanbaalenii_PYR-1 HKAHNAAEPGDQRLAIADWVYWQHLEVLLTDAVSTDAAV----------- TH_2928|M.thermoresistible__bu HRAHTASDAQVLREAIADWVYWQHVSVLTTDALAEFATAT---------- MSMEG_0805|M.smegmatis_MC2_155 HSAYTAADAEALRIDTEDAIYWQHVGVLSRDALGTMPEGSQSSERHRSRK MAV_5288|M.avium_104 LLAAIQALIDGHEYLAHYHLAWFQAINHRAGS------------------ * : . : * : Mb3909c|M.bovis_AF2122/97 --------------------------- Rv3879c|M.tuberculosis_H37Rv --------------------------- MMAR_5455|M.marinum_M --------------------------- Mflv_0760|M.gilvum_PYR-GCK --------------------------- Mvan_0085|M.vanbaalenii_PYR-1 --------------------------- TH_2928|M.thermoresistible__bu --------------------------- MSMEG_0805|M.smegmatis_MC2_155 WRRRVTRHAFDLSGPAESTRYRGCNAT MAV_5288|M.avium_104 ---------------------------