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MAAHALIGLVVVVLGAITIGVATRKRWQTAVVTAVVTVCGILAAVAAVRMFRPVSMQVLAICVLVGLLVL IRMTPTVALWVARVRPPHFGSITGRDLFARRAGMPVDTVAPVSEADADDEDNELTGITARGTAIAASARL VNAVQVGMCVGVSLVLPAAVWGVLTPRQPWAWLALLVAGLTVGLFITQGRGFAAKYQAVALVCGASAAVC AGVLKYALDTPKGVQTGLLWPAIFVAAFAALGLAVALVVPATRFRPIIRLTVEWLEVLAMIALLPAAAAL GGLFAWLRH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3917c | - | - | 100% (289) | transmembrane protein |
| M. bovis AF2122 / 97 | Mb1823 | - | 7e-23 | 25.09% (287) | hypothetical protein Mb1823 |
| M. bovis AF2122 / 97 | Mb3478 | - | 1e-08 | 25.17% (290) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4960 | - | 5e-05 | 22.81% (320) | hypothetical protein Mflv_4960 |
| M. tuberculosis H37Rv | Rv3887c | - | 1e-159 | 99.65% (288) | transmembrane protein |
| M. leprae Br4923 | MLBr_01539 | - | 4e-28 | 29.01% (293) | hypothetical protein MLBr_01539 |
| M. abscessus ATCC 19977 | MAB_2226c | - | 3e-05 | 23.23% (297) | hypothetical protein MAB_2226c |
| M. marinum M | MMAR_2677 | - | 1e-25 | 27.08% (288) | hypothetical protein MMAR_2677 |
| M. avium 104 | MAV_0157 | snm | 1e-136 | 82.64% (288) | secretion protein Snm4 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3996 | - | 3e-05 | 24.58% (301) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3080 | - | 1e-25 | 27.11% (284) | hypothetical protein MUL_3080 |
| M. vanbaalenii PYR-1 | Mvan_0081 | - | 1e-07 | 25.17% (294) | hypothetical protein Mvan_0081 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3917c|M.bovis_AF2122/97 --------------------------------------------------
Rv3887c|M.tuberculosis_H37Rv ---------MTAPHKVAFPARCAVNICYDKHLCSQVFPAGIPVEGFFEGM
MAV_0157|M.avium_104 ------------------------------------------MEGFFEGM
MMAR_2677|M.marinum_M MTAVADAPQAELEGVSSPRAVVVGIMAGEGVQIGVLLDANAPVSVMTDPL
MUL_3080|M.ulcerans_Agy99 MTAVADAPQAELEGVSSPRAVVVGIMAGEGVQIGVLLDANAPVSVMTDPL
MLBr_01539|M.leprae_Br4923 MTAVADAPRTDIEGTSSPRVVVVGIVAGEGAQISVLLDANAPVSVMTDPL
MAB_2226c|M.abscessus_ATCC_199 ------------MSDNAVMPIVRVAVLGEEKLTEVALPTQLPMRDIIPAV
Mvan_0081|M.vanbaalenii_PYR-1 -MTATVAPPTSSNVTPGRPTTTRVTILTGRRMTDLVLPSAAPIETYVDET
TH_3996|M.thermoresistible__bu ----VSDSVRRVSVQIDTLVDMLIGTDRGGTVIDVTLPSGVEVAELIPAI
Mflv_4960|M.gilvum_PYR-GCK ------------MPDTLCRLTVHVVGADESAAVDLVLPAACPLGELMPSL
Mb3917c|M.bovis_AF2122/97 --------------------------------------------------
Rv3887c|M.tuberculosis_H37Rv VELFDADLKRKGF---DGVALP-AGSYELHKINGVRLDINKSLDELGVQD
MAV_0157|M.avium_104 VELFDADLKRKGF---DGIALP-AGSYELHKINGVRLDINKSLDELGVQD
MMAR_2677|M.marinum_M LKVVNSRLRELGE---STLEAAGRGRWALCLIDGSPLRATQSLTEQDVYD
MUL_3080|M.ulcerans_Agy99 LKVVNSRLRELGE---STLEAAGRGRWALCLIDGSPLRATQSLTEQDVYD
MLBr_01539|M.leprae_Br4923 LKVINSRLCELGE---GTLEPTGRGRWALCLIDGTPLWPTQSLTEQDVYD
MAB_2226c|M.abscessus_ATCC_199 HRMVAP----------DATEATTPQRLSLAPVNGAPFSADATLDTVGVVD
Mvan_0081|M.vanbaalenii_PYR-1 VSVLADILADTPENVLADFDFKAQGVWSFARPGAPPIKLTESLDDAGVVD
TH_3996|M.thermoresistible__bu VDLAVG---------ADGVDAESPTAWKLARVGGTVLDASRTLTENGIRE
Mflv_4960|M.gilvum_PYR-GCK VDTIFG-------------DTAGQEHWQLTRVTGPPLNPALSLRDNDIGD
Mb3917c|M.bovis_AF2122/97 --------------------------------------------------
Rv3887c|M.tuberculosis_H37Rv GDTLVLVPRVAGESFEPQYESLSTGLAAMGKWLGRDGGDRMFAPVTSLTA
MAV_0157|M.avium_104 GDTLVLVPRVDGESFEPQYESLSSGLAAMGKWLGREGGDRMFAPVTPLTA
MMAR_2677|M.marinum_M GDRLWIRFIPDTEHRSQVIEHISTAVASN--------LSKRFASIDPVVA
MUL_3080|M.ulcerans_Agy99 GDRLWIRFIPDTEHRSQVIEHISTAVASN--------LSKRFASIDPVVA
MLBr_01539|M.leprae_Br4923 GDRLWIRFIADTERRSQVIEHISTAVSAN--------LSKRFAAIDSIVA
MAB_2226c|M.abscessus_ATCC_199 GDLLTLRPTPAGPAAPGIVEDIADAAVIFS--------ESRKRPWGAEHI
Mvan_0081|M.vanbaalenii_PYR-1 GSLLTVVSVSRTERYRPLVEDVIDAIAVL---------DETPEFDRSALY
TH_3996|M.thermoresistible__bu GELLMLTGAASAPVTRAEAPPGLEPAAGR---------------------
Mflv_4960|M.gilvum_PYR-GCK GDMVMLTASRVPSPRISPTEACTVVALAG----------------GNRES
Mb3917c|M.bovis_AF2122/97 --------------------------------------------------
Rv3887c|M.tuberculosis_H37Rv AHTAMAIIAMAVGVVLALTLRTRTITDSPVPAAMAGGIGVLLVIGALVVW
MAV_0157|M.avium_104 AHTAVAVIAMAVAVVVGLCLRARTFTDGPIPAAVAGGIGALLLIATLVVR
MMAR_2677|M.marinum_M VQVGAGMVGTGVILASGVLGWWRWHHNTWLTTIFASVIAVLVLMVAMMLL
MUL_3080|M.ulcerans_Agy99 VQVGAGMVGTGVILASGVLGWWRWHHNTWLTTIFASVIAVLVLMVAMMLL
MLBr_01539|M.leprae_Br4923 VQVGALMVATGVLASSVLLVWWRWHHGFWLSVIYATVIALLILVMSTLVL
MAB_2226c|M.abscessus_ATCC_199 ARVGRFGVLGLIAAATILAIVHSIRTGSSLSLAGLAVVAVAAAIGALVAH
Mvan_0081|M.vanbaalenii_PYR-1 RFVGLILPLAAFMVACVAILSWSSTGRDWWWAVALGVLGAGLMGGSVLAQ
TH_3996|M.thermoresistible__bu WHGARTALALWCPIAGTAAVVWTGLMRDDIGRTVPAAMLTVGAVAAVLPY
Mflv_4960|M.gilvum_PYR-GCK GHGATPWCIAGIIVAAVTLVRSGMVTPGGWHLWCAAALSGIAGTMSVALG
Mb3917c|M.bovis_AF2122/97 ----------------------------------------MAAHALIGLV
Rv3887c|M.tuberculosis_H37Rv WGWRERRDLFSG--FGWLAVVLLAVAAACAPPG-----ALGAAHALIGLV
MAV_0157|M.avium_104 SGWRERRDLFSG--FAWLAVVALAVAGACAPPG-----VLGAAHALIGVV
MMAR_2677|M.marinum_M MRATTDADRRVADIMLVSGLAPLTVAAASAPPG-----SVGSPQAVLGFG
MUL_3080|M.ulcerans_Agy99 MRATTDADRRVADIMLVSGLAPLTVAAASAPPG-----SVGSPQAALGFG
MLBr_01539|M.leprae_Br4923 MRATTREDRRAGDIMLLSGIAPVTAAAAAAPPG-----PLGSPHAVMGFG
MAB_2226c|M.abscessus_ATCC_199 VRS-----ARLGAELAVAALVPIAGALALAVPG-----SGLAPRVLLGAA
Mvan_0081|M.vanbaalenii_PYR-1 NRYR---HLDMAESLLVSSLVTLVGAVVLAVPLPEGVDSLGAPQVAGAGA
TH_3996|M.thermoresistible__bu RHRRDPLTATASALIVVMLAAVLGLLVVPDGPG--------PPNLMLAAA
Mflv_4960|M.gilvum_PYR-GCK RADRRVSTVLNTAAVVFAAATGVLAVPAAAWPA---------ATLLAAAS
. .
Mb3917c|M.bovis_AF2122/97 VVVLGAITIGVATRKRWQTAVVTAVVTVCGILAAVAAVRMFRPVSMQVLA
Rv3887c|M.tuberculosis_H37Rv VVVLGAITIGVATRKRWQTAVVTAVVTVCGILAAVAAVRMFRPVSMQVLA
MAV_0157|M.avium_104 VVILGAIAIGVTARNRWQTAVVTAVVTVCGVLAAVAAVRMFRPASVQVLA
MMAR_2677|M.marinum_M VLSIAAALALRFTGR--RLAIYTAIVTICGLTTLASLSRMVAATSAVTLF
MUL_3080|M.ulcerans_Agy99 VLSIAAALALRFTGR--RLAIYTAIVTICGLTTLASLSRMVAATSAVTLF
MLBr_01539|M.leprae_Br4923 VFAIAAMLALRFTGR--QLSIYTAMITISVVVAIASLARMVAMTSAVTLL
MAB_2226c|M.abscessus_ATCC_199 GVAAWSLIYLIVARQ--LIAFFTATTVLSLGIAGAAGAHVLWHPSLLVVG
Mvan_0081|M.vanbaalenii_PYR-1 LVLLMVLATRGGPRRRAEVAAFLAVIALALTIAAVAFG----YGWNDWVP
TH_3996|M.thermoresistible__bu AAAAAAMVMARLTGV--DIVGLTAVATGAAAVAISLIPAVLWPVPTVVIG
Mflv_4960|M.gilvum_PYR-GCK ALAMSTLLARMCPGA----ADLPAFCAVAGAVTAAAALSHLAAPRLTTAG
. * . . :
Mb3917c|M.bovis_AF2122/97 ICVLVGLLVLIRMTPTVALWVARVRPPHFGSITGRDLFARRAGMPVDTVA
Rv3887c|M.tuberculosis_H37Rv ICVLVGLLVLIRMTPTVALWVARVRPPHFGSITGRDLFARRAGMPVDTVA
MAV_0157|M.avium_104 ICVLVGLLVLVRMTPLIALWVARVRPPHFGSITGRDLFARREGMPVDTVA
MMAR_2677|M.marinum_M ATMLLICVVMYHASPALSRRLSGIRLPVFPSATSRWVFEARPDLPTTVAV
MUL_3080|M.ulcerans_Agy99 ATMLLICVVMYHASPALSRRLSGIRLPVFPSATSRWVFEARPDLPTTVAV
MLBr_01539|M.leprae_Br4923 SCVMLACVLLYHCAPALSRRLAGIRLPVFPSATSRWVFEARPDLPNTVVR
MAB_2226c|M.abscessus_ATCC_199 CGLIIVALLVTVRAAQLSAFAARFPLPTIP-------------------A
Mvan_0081|M.vanbaalenii_PYR-1 AGAIAFGLIVVTNAAKLTVAVARIALPPIPAPGETVTNDELLDPVTTTDA
TH_3996|M.thermoresistible__bu VLTASLSMAVLAVAPRLSIALAGLTPAPDGGPDAPG---------SLFDD
Mflv_4960|M.gilvum_PYR-GCK AVLVVLSLAGLAISPRITIALARLSP---------------------SRP
: :. :: : .
Mb3917c|M.bovis_AF2122/97 PVSEADADDEDNELTGITARGTAIAASARLVNAVQVGMCVGVSLVLPAAV
Rv3887c|M.tuberculosis_H37Rv PVSEADADDEDNELTDITARGTAIAASARLVNAVQVGMCVGVSLVLPAAV
MAV_0157|M.avium_104 PVSEDESEEQDNELTDITARGAAIAASARLVNAVQVGLCVGVSIVLPAAV
MMAR_2677|M.marinum_M AAGGPPVLEGPASVRDVVLQ-------AERARSFLSGLLVGLGVLMVVSL
MUL_3080|M.ulcerans_Agy99 AAGGPPVLEGPASVRDVVLQ-------AERARSFLSGLLVGLGVLMVVSL
MLBr_01539|M.leprae_Br4923 SDGGPPVLEGPASVRDVLLQ-------SERARSYLSGLLLGLGVLLVVSL
MAB_2226c|M.abscessus_ATCC_199 PGDATPSAPAMSVLKDLPRR-------VQLSDSHQSGFIAGASILAILGS
Mvan_0081|M.vanbaalenii_PYR-1 SEESETWQAIIASVPSSAAR---LTERSRLAKRLLIGFLSAGALILAAGS
TH_3996|M.thermoresistible__bu APAAPRLVRGNAILTGILTG-------AAVTAVIGTTLIALGGVLVGQAA
Mflv_4960|M.gilvum_PYR-GCK AVDDEEAAAAHTLLTALVAG-------WSSSAALGAVVVAAATIVSGASA
. : . :: .
Mb3917c|M.bovis_AF2122/97 WGVLTPRQPWAWLALLVAGLTVGLFITQGRGFAAKYQAVALVCGASAAVC
Rv3887c|M.tuberculosis_H37Rv WGVLTPRQPWAWLALLVAGLTVGLFITQGRGFAAKYQAVALVCGASAAVC
MAV_0157|M.avium_104 WGVLTPGRPWAWLALVVAGLVVGIFITQGRGFAAKYQAVALVCGASAAVC
MMAR_2677|M.marinum_M TSLCNPHTSERWLPLMLAGFTSGFLMLRGRSYVDRWQSITLAVTAVIVVA
MUL_3080|M.ulcerans_Agy99 TSLCNPHTSERWLPLMLAGFTSGFLMLRGRSYVDRWQSITLAVTAVIVVA
MLBr_01539|M.leprae_Br4923 TALSNPHVGQRWLPLLLAGFTSGFLLLRGRSYVDRWQAITLAATAVLIVA
MAB_2226c|M.abscessus_ATCC_199 LAVVGGAAPASPWAWYLVAAVSAGAALRARVWDSAVCKAWLLAVPFLVST
Mvan_0081|M.vanbaalenii_PYR-1 IAVVVQG-HFFLHSMIVAGLVTMLCGFRSRLYAERWCAWALMAAAVAVPT
TH_3996|M.thermoresistible__bu REPGSGPGGPWWTGPLFTALLAAALVLRARSHADALRRGVLVGCGVGCAT
Mflv_4960|M.gilvum_PYR-GCK G-----------LCAGLCVAAGVVLILRRNSHADGVRRLWLGTSGFIACA
. : . *
Mb3917c|M.bovis_AF2122/97 AGVLKYALDTPKGVQTGLLWPAIFVAAFAALGLAVALVVPA--TRFRPII
Rv3887c|M.tuberculosis_H37Rv AGVLKYALDTPKGVQTGLLWPAIFVAAFAALGLAVALVVPA--TRFRPII
MAV_0157|M.avium_104 AGVVKYALAAPHDAMTGLLWPVVAVTTFAAFGLAAALLVPA--MRFRPFI
MMAR_2677|M.marinum_M AVSVRYALVLSS--PLSVSIVASLLVLLPAAGMTAAAVVPN--TIYSPLF
MUL_3080|M.ulcerans_Agy99 AVSVRYALVLSS--PLSVSIVASLLVLLPAAGMTAAAVVPN--TIYSPLF
MLBr_01539|M.leprae_Br4923 AVVVRYALVLSS--PLAVSIGAAILVLLPAAGLIAAAVVPN--TIYSPLF
MAB_2226c|M.abscessus_ATCC_199 ALLVIFAVEDRYTGALVALGVLALLVAAVAVVVFNPKIGEA--ESYSLPS
Mvan_0081|M.vanbaalenii_PYR-1 GVVVRLCLWYPER---AWLLLAIYTALALLAVIVIGASEGV--RRISPVT
TH_3996|M.thermoresistible__bu MAFTAVVIEHPG-------QASAWGALAVAIGLVAAGGRPS--APVSPLI
Mflv_4960|M.gilvum_PYR-GCK AAVPAVADAAPA--------QAFWLSVAVAGGCVAGALRAGRPEPSNPAL
Mb3917c|M.bovis_AF2122/97 RLTVEWLEVLAMIALLPAAAALGGLFAWLRH----
Rv3887c|M.tuberculosis_H37Rv RLTVEWLEVLAMIALLPAAAALGGLFAWLRH----
MAV_0157|M.avium_104 RLTVEWVEVLAFIVLLPAAAALGGLFTWIRH----
MMAR_2677|M.marinum_M RKFVEWTEYLCLMPIFPLAFWLMNVYAAIRYR---
MUL_3080|M.ulcerans_Agy99 RKFVEWTEYLCLMPIFPLAFWLMNVYAAIRYR---
MLBr_01539|M.leprae_Br4923 RKLVEWIEYLCLVPIFPLALWLMDVYTAIRYR---
MAB_2226c|M.abscessus_ATCC_199 RRLLGFLASGIDASLLPVIAYLTGLFSWILNR---
Mvan_0081|M.vanbaalenii_PYR-1 KRILELLDGATIAAVIPMLLWIAGVYDVLRNLRF-
TH_3996|M.thermoresistible__bu RRAADVAECVVLAALAPLACWVAGVYGLVRGLALW
Mflv_4960|M.gilvum_PYR-GCK RHGIQVLEYVALAAVIPLAFWVSGVYGLVRDASLL
: : * : .:: :