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VGLWFGTLIALILLIAPGAMVARIAQLRWPVAIAVGPALTYGVVALAIIPYGALGIPWNGWTALAALAVT CAVATGLQLLLARFRDLDAEALAVSRWPAVTVAAGVLLGALLIGWAAYRGIPHWQSIPSTWDAVWHANTV RFILDTGQASSTHMGELRNVETHAPLYYPSVFHGLVAVFCQLTGAAPTTGYTLSSLAASVWLFPVSAAVL TWRAVRSHPGALWSASCASAEWRAAGAAGTAAALSASFTAVPYVEFDTAAMPNLAAYGIAVPTMVLITST LRHRDRIPVAVLALVGVFSLHITGGIVVALLVSAWWLFEALRHPVRSRLADLLTLAGVAAMAGLVMLPQF LSVRQQEDIIAGHAFPTYLSKKRGLFDAVFQHSRHLNDFPVQYALIVLAAIGGLILLVKKIWWPLAVWLL LIVMNVDAGTPLGGPIGGVAGALGEFFYHDPRRIAAATTLLLMLMAGVALFATVMLLVAAAKRLTDRFRP QPVSVWASATATLLIGATLVSAWHYFPRHRFLFGDKYDSVMIDQKDLDAMAYLASLPGARDTLIGNANTD GTAWMYAVAGLHPLWTHYDYPLQQGPGYHRFIFWAYGRNGESDPRVLEAIQVLRIRYILTSTPTVRGFAV PDGLVSLETSRSWAKIYDNGEARIYEWRGTAAATHS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3808 | - | - | 100% (666) | transmembrane protein alanine and leucine rich |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | - | - | - | - | - |
M. tuberculosis H37Rv | Rv3779 | - | 0.0 | 100.00% (666) | transmembrane protein alanine and leucine rich |
M. leprae Br4923 | MLBr_00116 | - | 0.0 | 66.52% (666) | hypothetical protein MLBr_00116 |
M. abscessus ATCC 19977 | MAB_0205c | - | 0.0 | 50.83% (663) | hypothetical protein MAB_0205c |
M. marinum M | MMAR_5334 | - | 0.0 | 81.38% (666) | transmembrane protein |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | - | - | - | - | - |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_0094 | - | 0.0 | 81.08% (666) | transmembrane protein |
M. vanbaalenii PYR-1 | Mvan_5631 | - | 7e-07 | 26.20% (355) | cell wall arabinan synthesis protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb3808|M.bovis_AF2122/97 --------MGLWFGTLIALILLIAPGAMVAR----------------IAQ Rv3779|M.tuberculosis_H37Rv --------MGLWFGTLIALILLIAPGAMVAR----------------IAQ MMAR_5334|M.marinum_M --------MTLWFGTLIALILLIAPGTLIAR----------------IAQ MUL_0094|M.ulcerans_Agy99 --------MTLWFGTLIALILLIAPGTLIAR----------------IAQ MLBr_00116|M.leprae_Br4923 --------MGLCCGTLIALFLLIVPETIVAR----------------FAA MAB_0205c|M.abscessus_ATCC_199 --------MSFAFGVAAALLLLFIPGWLIGR----------------ALG Mvan_5631|M.vanbaalenii_PYR-1 MPAPSARLVAVIAGLLGMLLCGLAPLLPVKQSTATITWPQSVNAEGFVSD : . * *: : * : : Mb3808|M.bovis_AF2122/97 LRWPVAIAVGPALTYGVVALAIIPYGALG------IPWNGWTALAALAVT Rv3779|M.tuberculosis_H37Rv LRWPVAIAVGPALTYGVVALAIIPYGALG------IPWNGWTALAALAVT MMAR_5334|M.marinum_M LSWPIAIAVGPPLTYGVIALAIVPYGALG------IPWNGWTALLALAVV MUL_0094|M.ulcerans_Agy99 LSWPIAIAVGPPLTYGVIALAIVPYGALG------IPWNGWTALVALAVV MLBr_00116|M.leprae_Br4923 LTWPIAIAVSPALTYGVIALVIIPFGAVG------IPWNSWTALAALVAV MAB_0205c|M.abscessus_ATCC_199 LPTHSAAVTAPALTYGLVGLCIVAFGSIG------IPWNSLSAGFALVGA Mvan_5631|M.vanbaalenii_PYR-1 ITAPLVSGAPHALDVTIPCPAVATLPGDDGVVFSTIPADGIDAGRNGLFV : . . .* : : . . . ** :. * . Mb3808|M.bovis_AF2122/97 CAVATGLQLLLARFRDLDAEALAVSRWPAVTVAAGVLLGALLIGWAAYRG Rv3779|M.tuberculosis_H37Rv CAVATGLQLLLARFRDLDAEALAVSRWPAVTVAAGVLLGALLIGWAAYRG MMAR_5334|M.marinum_M AAAVTGFQLLLGRFRDKEAEARGVSRGPALTVAAGVALGTLFIAWAAYRG MUL_0094|M.ulcerans_Agy99 TAAVTGFQLLLGRFRDKEAEARGVSRGPALTVAAGVALGTLFIAWAAYRG MLBr_00116|M.leprae_Br4923 SMLMIAFRLLLVRYRDTAAETRGISGWPAVTVAVGVLLGALLIGWAAYRG MAB_0205c|M.abscessus_ATCC_199 VIIARLLWRWLRPKRQ-AEQTPSQNRAALVAVTFGVALGMALIFYAFLRG Mvan_5631|M.vanbaalenii_PYR-1 RANADVVYVAFRDTVAAVAPREAVDSGACSELRIWAGVGAVGADFVGIPG . : . . . : . :* :. * Mb3808|M.bovis_AF2122/97 IP----------------HWQSIPSTWDAVWHANTVRFILD--------- Rv3779|M.tuberculosis_H37Rv IP----------------HWQSIPSTWDAVWHANTVRFILD--------- MMAR_5334|M.marinum_M IP----------------HWQSIPSTWDAVWHANTVRFILD--------- MUL_0094|M.ulcerans_Agy99 IP----------------HWQSIPSSWDAVWHANTVRFILD--------- MLBr_00116|M.leprae_Br4923 LL----------------HWQSIPSTWDAVWHANTVRFILD--------- MAB_0205c|M.abscessus_ATCC_199 LT----------------HWQSIPSTWDSMWHGNTIRYILD--------- Mvan_5631|M.vanbaalenii_PYR-1 AAGTLEPEKRPQVAGVFTDLEAGPDSGLRARIDVDTRFITTPTTVKLAVM . :: *.: *:* Mb3808|M.bovis_AF2122/97 --------------------TGQASSTHMGELRNVETHAPLYYPSVF--- Rv3779|M.tuberculosis_H37Rv --------------------TGQASSTHMGELRNVETHAPLYYPSVF--- MMAR_5334|M.marinum_M --------------------TGQASPTHMGELRNVETHALLYYPSVF--- MUL_0094|M.ulcerans_Agy99 --------------------TGQASPTHMGELRNVETHALLYYPSVF--- MLBr_00116|M.leprae_Br4923 --------------------TGQASPTHMGELRNVETHSVLYYPSVL--- MAB_0205c|M.abscessus_ATCC_199 --------------------TGQASSTRMGDLRNVETHATLYYPSAF--- Mvan_5631|M.vanbaalenii_PYR-1 VLGVLCVIAAIVALAVLDRASGRRMPRELRRRRRTGLWTWLTDAAVVGSL :*: . .: *.. : * .:.. Mb3808|M.bovis_AF2122/97 ------------HGLVAVFCQLTGAAPTTG-------------------- Rv3779|M.tuberculosis_H37Rv ------------HGLVAVFCQLTGAAPTTG-------------------- MMAR_5334|M.marinum_M ------------HGLTAVFCQLTGAAPTTG-------------------- MUL_0094|M.ulcerans_Agy99 ------------HGLTTVFCQLTGAAPTTG-------------------- MLBr_00116|M.leprae_Br4923 ------------HALAGVYCQLTGAAPTTG-------------------- MAB_0205c|M.abscessus_ATCC_199 ------------HGLAAVLCQLTGAAPTTS-------------------- Mvan_5631|M.vanbaalenii_PYR-1 LIWHLVGALSSDDGYNTTIARVSGEAGYITNYYRYFGASEAPFDWYQSVL .. . .:::* * Mb3808|M.bovis_AF2122/97 --YTLSSLAASVWLFPVSAAVLTWRAVRSHPGALWSASCASAEWRAAGAA Rv3779|M.tuberculosis_H37Rv --YTLSSLAASVWLFPVSAAVLTWRAVRSHPGALWSASCASAEWRAAGAA MMAR_5334|M.marinum_M --YTLNSLAAAIWLFPVSAATLTWRAMRGH----------LTEWRTAGSA MUL_0094|M.ulcerans_Agy99 --YTLNSLAAAIWLFPVSAATLTWRAMRGH----------LTEWRTAGSA MLBr_00116|M.leprae_Br4923 --YTVSSLAVAVWLFPVSAATLTWHLLRPV----------TTQKRAAGAS MAB_0205c|M.abscessus_ATCC_199 --YTLYAVAGS-LLFPLGSAALAWQMLRGR----------TTRTFQAGAA Mvan_5631|M.vanbaalenii_PYR-1 AQLASISTASVWLRLPATAAAIGTWLIVSR-------CVLPRLGRRVADN : : * :* :*.: : .. Mb3808|M.bovis_AF2122/97 GTAAALSASFTAVPYVEFDTAAMPNLAAYGIAVPTMVLITSTLRHRDRIP Rv3779|M.tuberculosis_H37Rv GTAAALSASFTAVPYVEFDTAAMPNLAAYGIAVPTMVLITSTLRHRDRIP MMAR_5334|M.marinum_M ATAAALSASFTALPYVEFGTAAMPNLASYGVAVPAMVLITSTPRHRDRIP MUL_0094|M.ulcerans_Agy99 ATAAALSASFTALPYVEFGTAAMPNLASYGVAVPAMVLITSTPRHRDRIP MLBr_00116|M.leprae_Br4923 ATAAALSAAFTSVPYVEFGVAAMPNLAAYGVAVPTMVLITSTLRHRDRIP MAB_0205c|M.abscessus_ATCC_199 ATAAALSASFSALPYVEFHVSAIPNLMSFALVGPALLAITSVVADRSRIP Mvan_5631|M.vanbaalenii_PYR-1 RVAVLTGGAVFLAAWLPFNNGLRPEPLIAFGVVAAWILTERALATRRLWP .*. ..:. .:: * . *: . .: : . * * Mb3808|M.bovis_AF2122/97 VAVLALVGVFSLHITGGIVVALLVSAWWLFEALRHPVRSRLADLLTLAG- Rv3779|M.tuberculosis_H37Rv VAVLALVGVFSLHITGGIVVALLVSAWWLFEALRHPVRSRLADLLTLAG- MMAR_5334|M.marinum_M IAVLALVGVLSVHIAGGMVVVLLVAAWWLFEALWHPVRGRLADLATLAG- MUL_0094|M.ulcerans_Agy99 IAVLALVGVLSVHIAGGMVVVLLVAAWWLFGALWHPVRGRLADLATLAG- MLBr_00116|M.leprae_Br4923 VAILALVGTFSVHLTGGIVVSLFLLGWWLMNALLHPVRSRAADARTLAA- MAB_0205c|M.abscessus_ATCC_199 AAILAFTGVASVHTSGAIVVVVFVAAWWVLAPLSRYPGTKSKDKHRLGSG Mvan_5631|M.vanbaalenii_PYR-1 YAVAIVVAVFSVTLAPQGLVALAPLLVGARGVTRIVAARRPVDGLAAQLA *: .... *: : :* : : * Mb3808|M.bovis_AF2122/97 -----VAAMAGLVML-PQFLSVRQQE--DIIAGHAFPTYLSKKRGLFDAV Rv3779|M.tuberculosis_H37Rv -----VAAMAGLVML-PQFLSVRQQE--DIIAGHAFPTYLSKKRGLFDAV MMAR_5334|M.marinum_M -----VAAISGLIML-PQFISVEQQE--DIIAGHSFLTYLSKKRGVFDAV MUL_0094|M.ulcerans_Agy99 -----VAAISGLIML-PQFISVEQQE--DIIAGHSFLTYLSKKRGVFDAV MLBr_00116|M.leprae_Br4923 -----VVMPTALILA-PQFIAVLNQA--DIIAGHSFPSFKSVKQGVIDAL MAB_0205c|M.abscessus_ATCC_199 FTPLAVAGVGSLVLLYPQLRTLMQLS--EIIAGHQFTTPWGKKRALLDAL Mvan_5631|M.vanbaalenii_PYR-1 PLAAAASLLFVVVFRDQTLATVAESVRIKYVVGPTIPWYQEFLRYYFLTV . ::: : :: : . :.* : : : :: Mb3808|M.bovis_AF2122/97 FQHSRHLNDFPVQYALIVLAAIGGLILLVKKIWWP--------------L Rv3779|M.tuberculosis_H37Rv FQHSRHLNDFPVQYALIVLAAIGGLILLVKKIWWP--------------L MMAR_5334|M.marinum_M FQHSRHLNDFPVQYALIALAAIGGFILLIKKIWWP--------------L MUL_0094|M.ulcerans_Agy99 FQHSRHLNDFPVQYALIALAAIGGFILLIKKIWWP--------------L MLBr_00116|M.leprae_Br4923 LLHTRHLNDFPIQYGLVVLAAIGMAILLYQKIWWP--------------S MAB_0205c|M.abscessus_ATCC_199 TQHTRHLADYPVQSALLGLALIGAVVLIVKRVYWP--------------V Mvan_5631|M.vanbaalenii_PYR-1 EESVDGSLTRRFSVLILLLCLFGVLMVLLRRGSLPGAVNGPVWRLAGTTA .. :: *. :* ::: :: * Mb3808|M.bovis_AF2122/97 AVWLLLIVMNVDAGTPLGGPIGGVAGA-------LGEFFYHDPRRIAAAT Rv3779|M.tuberculosis_H37Rv AVWLLLIVMNVDAGTPLGGPIGGVAGA-------LGEFFYHDPRRIAAAT MMAR_5334|M.marinum_M AVWVLLVVMNVNAGTPLGGPIDAMAGA-------LGEFFYNDPRRIAAAT MUL_0094|M.ulcerans_Agy99 AVWLLLVVMNVNAGTPLGGPIDAMAGS-------LGEFFYNDPRRIAAAT MLBr_00116|M.leprae_Br4923 IAWLVLTVATVYSAAPFRGPIGSAIES-------FSQFFYNDPRRLSAVV MAB_0205c|M.abscessus_ATCC_199 AVWLLLVIAIVHSSKPFGGFVGHAVAL-------FSDAFYSDPRRLSAIV Mvan_5631|M.vanbaalenii_PYR-1 IGLLLLTLTPTKWAVQFGVFAGLAGALGAITAFAFARVGLHSRRNLALYV ::* : . . : . :. . *.:: . Mb3808|M.bovis_AF2122/97 TLLLMLMAG----------------------------------------- Rv3779|M.tuberculosis_H37Rv TLLLMLMAG----------------------------------------- MMAR_5334|M.marinum_M TLLLMLMAG----------------------------------------- MUL_0094|M.ulcerans_Agy99 TLLLMLMAG----------------------------------------- MLBr_00116|M.leprae_Br4923 TMLLTPMAG----------------------------------------- MAB_0205c|M.abscessus_ATCC_199 CLLLAPAAG----------------------------------------- Mvan_5631|M.vanbaalenii_PYR-1 TALLFVLAWATSGINGWFYVGNYGVPWFDKQPVIVGYPVTTIFLVLAIAC ** * Mb3808|M.bovis_AF2122/97 ------------------------------VALFATVMLLVAAAKRLTDR Rv3779|M.tuberculosis_H37Rv ------------------------------VALFATVMLLVAAAKRLTDR MMAR_5334|M.marinum_M ------------------------------VALFWIVTLVVTAAQGLTDR MUL_0094|M.ulcerans_Agy99 ------------------------------VALFWIVTLVVAAARGLTDR MLBr_00116|M.leprae_Br4923 ------------------------------IALFAGVLLLVVGARRVTAR MAB_0205c|M.abscessus_ATCC_199 ------------------------------IGLFALAAAALATLR--RAR Mvan_5631|M.vanbaalenii_PYR-1 GLLAGWLHFRMDYAGHTEVADTGRNRALASTPLLVVAVIMVVLELGSMLK *: . :. : Mb3808|M.bovis_AF2122/97 FRPQPVSVWASATATLLIGATLVSAWHYFPRHRFLFGDKYDSVMIDQK-- Rv3779|M.tuberculosis_H37Rv FRPQPVSVWASATATLLIGATLVSAWHYFPRHRFLFGDKYDSVMIDQK-- MMAR_5334|M.marinum_M FRPLPQPFWVSVTVALLLGVCLVSTWHYFPRHRFLFGDKYDSVMIDQK-- MUL_0094|M.ulcerans_Agy99 FRPLPQPFWVSVTVALLLGVCLVSTWHYFPRHRFLFGDKYDSVMIDQK-- MLBr_00116|M.leprae_Br4923 FTALPRPVWTTATVVLLVAATVLTAWHYLFRHLVLFGDKYDSVMVNQK-- MAB_0205c|M.abscessus_ATCC_199 KTRADSRWTLVAAAIVLAAICGFSARHYFLPHKYLVGAKYDQVMVGPK-- Mvan_5631|M.vanbaalenii_PYR-1 ATAGRYPVYTTGAANISALRSGLSDASCSMADAVLVEADTNAGMLTPVPG :. : .: . *. . : *: Mb3808|M.bovis_AF2122/97 ------------------------DLDAMAYLASLPGARDT-------LI Rv3779|M.tuberculosis_H37Rv ------------------------DLDAMAYLASLPGARDT-------LI MMAR_5334|M.marinum_M ------------------------DLDAMAYLATLPGARDT-------MI MUL_0094|M.ulcerans_Agy99 ------------------------DLDAMAYLATLPGARDT-------MI MLBr_00116|M.leprae_Br4923 ------------------------DLDAMSYLATLPGAHNT-------II MAB_0205c|M.abscessus_ATCC_199 ------------------------KLDAFAYLATLPGAKTT-------TI Mvan_5631|M.vanbaalenii_PYR-1 QRFGEYGPLGGEDPVGFTPNGVSDTLEPAEPVAANPGTVNSDGPVDKPNI *:. :*: **: : * Mb3808|M.bovis_AF2122/97 GNANTDGTA----------------------------------------- Rv3779|M.tuberculosis_H37Rv GNANTDGTA----------------------------------------- MMAR_5334|M.marinum_M GNANTDGTA----------------------------------------- MUL_0094|M.ulcerans_Agy99 GDANTDGTA----------------------------------------- MLBr_00116|M.leprae_Br4923 GNSNTDGSS----------------------------------------- MAB_0205c|M.abscessus_ATCC_199 GDGNVDGSG----------------------------------------- Mvan_5631|M.vanbaalenii_PYR-1 GVGYAAGTGGGYGPEGVNGSRVFLPFGLDPATTPVMGSFDENTLAAKATS * . . *:. Mb3808|M.bovis_AF2122/97 -----------------------WMYAVAG-------------------- Rv3779|M.tuberculosis_H37Rv -----------------------WMYAVAG-------------------- MMAR_5334|M.marinum_M -----------------------WMYAVAG-------------------- MUL_0094|M.ulcerans_Agy99 -----------------------WMYAVAG-------------------- MLBr_00116|M.leprae_Br4923 -----------------------WMYAVAD-------------------- MAB_0205c|M.abscessus_ATCC_199 -----------------------WMYAVAG-------------------- Mvan_5631|M.vanbaalenii_PYR-1 AWYQLPPRTPDRPLVSVAAAGAIWYYNEDGSFNYGQSLKLQWGVHRPDGS * * . Mb3808|M.bovis_AF2122/97 -------------LHPLWTHYDYPLQQGP--------------------- Rv3779|M.tuberculosis_H37Rv -------------LHPLWTHYDYPLQQGP--------------------- MMAR_5334|M.marinum_M -------------LHPLWTHYDYPVQQGP--------------------- MUL_0094|M.ulcerans_Agy99 -------------LHPLWTHYDYPVQQGP--------------------- MLBr_00116|M.leprae_Br4923 -------------LHPLWTHYDFPQQTGP--------------------- MAB_0205c|M.abscessus_ATCC_199 -------------LHPLWTHYDFPQQQGP--------------------- Mvan_5631|M.vanbaalenii_PYR-1 YQELGEVQPIDIFVQKAWRNLRFPLEWAPPEANVARIVADDPNLSEDQWF :: * : :* : .* Mb3808|M.bovis_AF2122/97 -------------------------------------------------- Rv3779|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5334|M.marinum_M -------------------------------------------------- MUL_0094|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00116|M.leprae_Br4923 -------------------------------------------------- MAB_0205c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_5631|M.vanbaalenii_PYR-1 AFTPPRVPVLQTAQDFLGRQTPVLMDIATAANFPCQRPFTEHLGIAELPE Mb3808|M.bovis_AF2122/97 -----GYHRFIF----WAYGRNGESDPRVLEAIQVLRIRYILTSTPTVRG Rv3779|M.tuberculosis_H37Rv -----GYHRFIF----WAYGRNGESDPRVLEAIQVLRIRYILTSTPTVRG MMAR_5334|M.marinum_M -----GYHRFIV----WAYAGRGDSDPRVVESIKVLNIRYILTSSPTVRG MUL_0094|M.ulcerans_Agy99 -----GYHRFIF----WAYAGRGDSDPRVVESIKVLNIRYILTSSPTVRG MLBr_00116|M.leprae_Br4923 -----GYFRYAF----WAYARTG--NPWVVEAVRVFNIRYILTTSPTVQG MAB_0205c|M.abscessus_ATCC_199 -----GYHRYIF----WAYADDADTDRRVTEAVHALNIRYVMTSTPVVQG Mvan_5631|M.vanbaalenii_PYR-1 YRIMPNFKQIVVSSNQWQAAQDGGPFLFIQALLRTESIPTYLSGDWYRDW .: : . * . . : ::. * :: Mb3808|M.bovis_AF2122/97 FAVPDGLVSLETSRSWAKIYDNGEARIYEWRGTAAATHS--- Rv3779|M.tuberculosis_H37Rv FAVPDGLVSLETSRSWAKIYDNGEARIYEWRGTAAATHS--- MMAR_5334|M.marinum_M FAVPDGLVSLENSPSWKKIYDNGGARIYEWSGKTAQTHSK-- MUL_0094|M.ulcerans_Agy99 FAVPDGLVSLENSPSWKKIYDNGGARIYEWSGKTAQTHSK-- MLBr_00116|M.leprae_Br4923 FAIPDGLVSLEESKSWTKIYDNGAARIFEWSGNATATRA--- MAB_0205c|M.abscessus_ATCC_199 FKVPDGLRSLDISRSWRKLYDNGAAQIYEWVGDRKPDAEGDK Mvan_5631|M.vanbaalenii_PYR-1 GSLERYLRVVPKDEAPDAVIEEGSTRVFGWSRGGPIRALP-- : * : . : : ::* :::: *