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M. ulcerans Agy99 MUL_0094 (-)

annotation: transmembrane protein
coordinates: 90312 - 92285
length: 657

TLWFGTLIALILLIAPGTLIARIAQLSWPIAIAVGPPLTYGVIALAIVPYGALGIPWNGWTALVALAVVT
AAVTGFQLLLGRFRDKEAEARGVSRGPALTVAAGVALGTLFIAWAAYRGIPHWQSIPSSWDAVWHANTVR
FILDTGQASPTHMGELRNVETHALLYYPSVFHGLTTVFCQLTGAAPTTGYTLNSLAAAIWLFPVSAATLT
WRAMRGHLTEWRTAGSAATAAALSASFTALPYVEFGTAAMPNLASYGVAVPAMVLITSTPRHRDRIPIAV
LALVGVLSVHIAGGMVVVLLVAAWWLFGALWHPVRGRLADLATLAGVAAISGLIMLPQFISVEQQEDIIA
GHSFLTYLSKKRGVFDAVFQHSRHLNDFPVQYALIALAAIGGFILLIKKIWWPLAVWLLLVVMNVNAGTP
LGGPIDAMAGSLGEFFYNDPRRIAAATTLLLMLMAGVALFWIVTLVVAAARGLTDRFRPLPQPFWVSVTV
ALLLGVCLVSTWHYFPRHRFLFGDKYDSVMIDQKDLDAMAYLATLPGARDTMIGDANTDGTAWMYAVAGL
HPLWTHYDYPVQQGPGYHRFIFWAYAGRGDSDPRVVESIKVLNIRYILTSSPTVRGFAVPDGLVSLENSP
SWKKIYDNGGARIYEWSGKTAQTHSK*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_0094--100% (657)transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3808-0.081.08% (666) transmembrane protein alanine and leucine rich
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv3779-0.081.08% (666) transmembrane protein alanine and leucine rich
M. leprae Br4923MLBr_00116-0.066.01% (656) hypothetical protein MLBr_00116
M. abscessus ATCC 19977MAB_0205c-0.052.21% (655) hypothetical protein MAB_0205c
M. marinum MMMAR_5334-0.098.33% (657) transmembrane protein
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MUL_0094|M.ulcerans_Agy99           MTLWFGTLIALILLIAPGTLIARIAQLSWPIAIAVGPPLTYGVIALAIVP
MMAR_5334|M.marinum_M               MTLWFGTLIALILLIAPGTLIARIAQLSWPIAIAVGPPLTYGVIALAIVP
Mb3808|M.bovis_AF2122/97            MGLWFGTLIALILLIAPGAMVARIAQLRWPVAIAVGPALTYGVVALAIIP
Rv3779|M.tuberculosis_H37Rv         MGLWFGTLIALILLIAPGAMVARIAQLRWPVAIAVGPALTYGVVALAIIP
MLBr_00116|M.leprae_Br4923          MGLCCGTLIALFLLIVPETIVARFAALTWPIAIAVSPALTYGVIALVIIP
MAB_0205c|M.abscessus_ATCC_199      MSFAFGVAAALLLLFIPGWLIGRALGLPTHSAAVTAPALTYGLVGLCIVA
                                    * :  *.  **:**: *  ::.*   *    * ...*.****::.* *:.

MUL_0094|M.ulcerans_Agy99           YGALGIPWNGWTALVALAVVTAAVTGFQLLLGRFRDKEAEARGVSRGPAL
MMAR_5334|M.marinum_M               YGALGIPWNGWTALLALAVVAAAVTGFQLLLGRFRDKEAEARGVSRGPAL
Mb3808|M.bovis_AF2122/97            YGALGIPWNGWTALAALAVTCAVATGLQLLLARFRDLDAEALAVSRWPAV
Rv3779|M.tuberculosis_H37Rv         YGALGIPWNGWTALAALAVTCAVATGLQLLLARFRDLDAEALAVSRWPAV
MLBr_00116|M.leprae_Br4923          FGAVGIPWNSWTALAALVAVSMLMIAFRLLLVRYRDTAAETRGISGWPAV
MAB_0205c|M.abscessus_ATCC_199      FGSIGIPWNSLSAGFALVGAVIIARLLWRWLRPKRQ-AEQTPSQNRAALV
                                    :*::*****. :*  **. .      :   *   *:   :: . .  . :

MUL_0094|M.ulcerans_Agy99           TVAAGVALGTLFIAWAAYRGIPHWQSIPSSWDAVWHANTVRFILDTGQAS
MMAR_5334|M.marinum_M               TVAAGVALGTLFIAWAAYRGIPHWQSIPSTWDAVWHANTVRFILDTGQAS
Mb3808|M.bovis_AF2122/97            TVAAGVLLGALLIGWAAYRGIPHWQSIPSTWDAVWHANTVRFILDTGQAS
Rv3779|M.tuberculosis_H37Rv         TVAAGVLLGALLIGWAAYRGIPHWQSIPSTWDAVWHANTVRFILDTGQAS
MLBr_00116|M.leprae_Br4923          TVAVGVLLGALLIGWAAYRGLLHWQSIPSTWDAVWHANTVRFILDTGQAS
MAB_0205c|M.abscessus_ATCC_199      AVTFGVALGMALIFYAFLRGLTHWQSIPSTWDSMWHGNTIRYILDTGQAS
                                    :*: ** **  :* :*  **: *******:**::**.**:*:********

MUL_0094|M.ulcerans_Agy99           PTHMGELRNVETHALLYYPSVFHGLTTVFCQLTGAAPTTGYTLNSLAAAI
MMAR_5334|M.marinum_M               PTHMGELRNVETHALLYYPSVFHGLTAVFCQLTGAAPTTGYTLNSLAAAI
Mb3808|M.bovis_AF2122/97            STHMGELRNVETHAPLYYPSVFHGLVAVFCQLTGAAPTTGYTLSSLAASV
Rv3779|M.tuberculosis_H37Rv         STHMGELRNVETHAPLYYPSVFHGLVAVFCQLTGAAPTTGYTLSSLAASV
MLBr_00116|M.leprae_Br4923          PTHMGELRNVETHSVLYYPSVLHALAGVYCQLTGAAPTTGYTVSSLAVAV
MAB_0205c|M.abscessus_ATCC_199      STRMGDLRNVETHATLYYPSAFHGLAAVLCQLTGAAPTTSYTLYAVAGS-
                                    .*:**:*******: *****.:*.*. * **********.**: ::* : 

MUL_0094|M.ulcerans_Agy99           WLFPVSAATLTWRAMRGH----------LTEWRTAGSAATAAALSASFTA
MMAR_5334|M.marinum_M               WLFPVSAATLTWRAMRGH----------LTEWRTAGSAATAAALSASFTA
Mb3808|M.bovis_AF2122/97            WLFPVSAAVLTWRAVRSHPGALWSASCASAEWRAAGAAGTAAALSASFTA
Rv3779|M.tuberculosis_H37Rv         WLFPVSAAVLTWRAVRSHPGALWSASCASAEWRAAGAAGTAAALSASFTA
MLBr_00116|M.leprae_Br4923          WLFPVSAATLTWHLLRPV----------TTQKRAAGASATAAALSAAFTS
MAB_0205c|M.abscessus_ATCC_199      LLFPLGSAALAWQMLRGR----------TTRTFQAGAAATAAALSASFSA
                                     ***:.:*.*:*: :*             :.   **::.*******:*::

MUL_0094|M.ulcerans_Agy99           LPYVEFGTAAMPNLASYGVAVPAMVLITSTPRHRDRIPIAVLALVGVLSV
MMAR_5334|M.marinum_M               LPYVEFGTAAMPNLASYGVAVPAMVLITSTPRHRDRIPIAVLALVGVLSV
Mb3808|M.bovis_AF2122/97            VPYVEFDTAAMPNLAAYGIAVPTMVLITSTLRHRDRIPVAVLALVGVFSL
Rv3779|M.tuberculosis_H37Rv         VPYVEFDTAAMPNLAAYGIAVPTMVLITSTLRHRDRIPVAVLALVGVFSL
MLBr_00116|M.leprae_Br4923          VPYVEFGVAAMPNLAAYGVAVPTMVLITSTLRHRDRIPVAILALVGTFSV
MAB_0205c|M.abscessus_ATCC_199      LPYVEFHVSAIPNLMSFALVGPALLAITSVVADRSRIPAAILAFTGVASV
                                    :***** .:*:*** ::.:. *::: ***.  .*.*** *:**:.*. *:

MUL_0094|M.ulcerans_Agy99           HIAGGMVVVLLVAAWWLFGALWHPVRGRLADLATLAG------VAAISGL
MMAR_5334|M.marinum_M               HIAGGMVVVLLVAAWWLFEALWHPVRGRLADLATLAG------VAAISGL
Mb3808|M.bovis_AF2122/97            HITGGIVVALLVSAWWLFEALRHPVRSRLADLLTLAG------VAAMAGL
Rv3779|M.tuberculosis_H37Rv         HITGGIVVALLVSAWWLFEALRHPVRSRLADLLTLAG------VAAMAGL
MLBr_00116|M.leprae_Br4923          HLTGGIVVSLFLLGWWLMNALLHPVRSRAADARTLAA------VVMPTAL
MAB_0205c|M.abscessus_ATCC_199      HTSGAIVVVVFVAAWWVLAPLSRYPGTKSKDKHRLGSGFTPLAVAGVGSL
                                    * :*.:** ::: .**:: .* :    :  *   *..      *.   .*

MUL_0094|M.ulcerans_Agy99           IML-PQFISVEQQEDIIAGHSFLTYLSKKRGVFDAVFQHSRHLNDFPVQY
MMAR_5334|M.marinum_M               IML-PQFISVEQQEDIIAGHSFLTYLSKKRGVFDAVFQHSRHLNDFPVQY
Mb3808|M.bovis_AF2122/97            VML-PQFLSVRQQEDIIAGHAFPTYLSKKRGLFDAVFQHSRHLNDFPVQY
Rv3779|M.tuberculosis_H37Rv         VML-PQFLSVRQQEDIIAGHAFPTYLSKKRGLFDAVFQHSRHLNDFPVQY
MLBr_00116|M.leprae_Br4923          ILA-PQFIAVLNQADIIAGHSFPSFKSVKQGVIDALLLHTRHLNDFPIQY
MAB_0205c|M.abscessus_ATCC_199      VLLYPQLRTLMQLSEIIAGHQFTTPWGKKRALLDALTQHTRHLADYPVQS
                                    ::  **: :: :  :***** * :  . *:.::**:  *:*** *:*:* 

MUL_0094|M.ulcerans_Agy99           ALIALAAIGGFILLIKKIWWPLAVWLLLVVMNVNAGTPLGGPIDAMAGSL
MMAR_5334|M.marinum_M               ALIALAAIGGFILLIKKIWWPLAVWVLLVVMNVNAGTPLGGPIDAMAGAL
Mb3808|M.bovis_AF2122/97            ALIVLAAIGGLILLVKKIWWPLAVWLLLIVMNVDAGTPLGGPIGGVAGAL
Rv3779|M.tuberculosis_H37Rv         ALIVLAAIGGLILLVKKIWWPLAVWLLLIVMNVDAGTPLGGPIGGVAGAL
MLBr_00116|M.leprae_Br4923          GLVVLAAIGMAILLYQKIWWPSIAWLVLTVATVYSAAPFRGPIGSAIESF
MAB_0205c|M.abscessus_ATCC_199      ALLGLALIGAVVLIVKRVYWPVAVWLLLVIAIVHSSKPFGGFVGHAVALF
                                    .*: ** **  :*: ::::**  .*::* :  * :. *: * :.     :

MUL_0094|M.ulcerans_Agy99           GEFFYNDPRRIAAATTLLLMLMAGVALFWIVTLVVAAARGLTDRFRPLPQ
MMAR_5334|M.marinum_M               GEFFYNDPRRIAAATTLLLMLMAGVALFWIVTLVVTAAQGLTDRFRPLPQ
Mb3808|M.bovis_AF2122/97            GEFFYHDPRRIAAATTLLLMLMAGVALFATVMLLVAAAKRLTDRFRPQPV
Rv3779|M.tuberculosis_H37Rv         GEFFYHDPRRIAAATTLLLMLMAGVALFATVMLLVAAAKRLTDRFRPQPV
MLBr_00116|M.leprae_Br4923          SQFFYNDPRRLSAVVTMLLTPMAGIALFAGVLLLVVGARRVTARFTALPR
MAB_0205c|M.abscessus_ATCC_199      SDAFYSDPRRLSAIVCLLLAPAAGIGLFALAAAALATLR--RARKTRADS
                                    .: ** ****::* . :**   **:.**  .   :.  :    *      

MUL_0094|M.ulcerans_Agy99           PFWVSVTVALLLGVCLVSTWHYFPRHRFLFGDKYDSVMIDQKDLDAMAYL
MMAR_5334|M.marinum_M               PFWVSVTVALLLGVCLVSTWHYFPRHRFLFGDKYDSVMIDQKDLDAMAYL
Mb3808|M.bovis_AF2122/97            SVWASATATLLIGATLVSAWHYFPRHRFLFGDKYDSVMIDQKDLDAMAYL
Rv3779|M.tuberculosis_H37Rv         SVWASATATLLIGATLVSAWHYFPRHRFLFGDKYDSVMIDQKDLDAMAYL
MLBr_00116|M.leprae_Br4923          PVWTTATVVLLVAATVLTAWHYLFRHLVLFGDKYDSVMVNQKDLDAMSYL
MAB_0205c|M.abscessus_ATCC_199      RWTLVAAAIVLAAICGFSARHYFLPHKYLVGAKYDQVMVGPKKLDAFAYL
                                         .:. :* .   .:: **:  *  *.* ***.**:. *.***::**

MUL_0094|M.ulcerans_Agy99           ATLPGARDTMIGDANTDGTAWMYAVAGLHPLWTHYDYPVQQGPGYHRFIF
MMAR_5334|M.marinum_M               ATLPGARDTMIGNANTDGTAWMYAVAGLHPLWTHYDYPVQQGPGYHRFIV
Mb3808|M.bovis_AF2122/97            ASLPGARDTLIGNANTDGTAWMYAVAGLHPLWTHYDYPLQQGPGYHRFIF
Rv3779|M.tuberculosis_H37Rv         ASLPGARDTLIGNANTDGTAWMYAVAGLHPLWTHYDYPLQQGPGYHRFIF
MLBr_00116|M.leprae_Br4923          ATLPGAHNTIIGNSNTDGSSWMYAVADLHPLWTHYDFPQQTGPGYFRYAF
MAB_0205c|M.abscessus_ATCC_199      ATLPGAKTTTIGDGNVDGSGWMYAVAGLHPLWTHYDFPQQQGPGYHRYIF
                                    *:****: * **:.*.**:.******.*********:* * ****.*: .

MUL_0094|M.ulcerans_Agy99           WAYAGRGDSDPRVVESIKVLNIRYILTSSPTVRGFAVPDGLVSLENSPSW
MMAR_5334|M.marinum_M               WAYAGRGDSDPRVVESIKVLNIRYILTSSPTVRGFAVPDGLVSLENSPSW
Mb3808|M.bovis_AF2122/97            WAYGRNGESDPRVLEAIQVLRIRYILTSTPTVRGFAVPDGLVSLETSRSW
Rv3779|M.tuberculosis_H37Rv         WAYGRNGESDPRVLEAIQVLRIRYILTSTPTVRGFAVPDGLVSLETSRSW
MLBr_00116|M.leprae_Br4923          WAYARTG--NPWVVEAVRVFNIRYILTTSPTVQGFAIPDGLVSLEESKSW
MAB_0205c|M.abscessus_ATCC_199      WAYADDADTDRRVTEAVHALNIRYVMTSTPVVQGFKVPDGLRSLDISRSW
                                    ***.  .  :  * *:::.:.***::*::*.*:** :**** **: * **

MUL_0094|M.ulcerans_Agy99           KKIYDNGGARIYEWSGKTAQTHSK--
MMAR_5334|M.marinum_M               KKIYDNGGARIYEWSGKTAQTHSK--
Mb3808|M.bovis_AF2122/97            AKIYDNGEARIYEWRGTAAATHS---
Rv3779|M.tuberculosis_H37Rv         AKIYDNGEARIYEWRGTAAATHS---
MLBr_00116|M.leprae_Br4923          TKIYDNGAARIFEWSGNATATRA---
MAB_0205c|M.abscessus_ATCC_199      RKLYDNGAAQIYEWVGDRKPDAEGDK
                                     *:**** *:*:** *