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VTVLGADAVVIDGRICRPGWVHTADGRILSGGAGAPPMPADAEFPDAIVVPGFVDMHVHGGGGASFADGN AADIARAAEFHLRHGTTTTLASLVTAGPAELLSAVGALAEATRDGVVAGIHLEGPWLSPARCGAHDHTRM RAPDPAEIESVLAAADGAVRMVTLAPELPGSDAAIRRFRDAEVVVAVGHTDATYTQTRHAIDLGATVGTH LFNAMPPLDHRAPGPVLALLCDPRVTVEIIADGVHVHPAVVHAVIEAVGPDRVAVVTDAIAAAGCGDGAF RLGTMPIEVESSVARVAGASTLAGSTTTMDQLFRTVAGLGSKSDSAGDVALAAAVQVTSATPARALGLTG VGRLAAGYAANLVVLDRDLRVTAVMVNDDWRVG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3365 | nagA | - | 100% (383) | N-acetylglucosamine-6-phosphate deacetylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2437 | - | 3e-07 | 33.57% (143) | amidohydrolase |
| M. tuberculosis H37Rv | Rv3332 | nagA | 0.0 | 100.00% (383) | N-acetylglucosamine-6-phosphate deacetylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0362c | - | 1e-81 | 53.16% (301) | N-acetylglucosamine-6-phosphate deacetylase NagA |
| M. marinum M | MMAR_1190 | nagA | 1e-148 | 70.36% (388) | N-acetylglucosamine-6-phosphate deacetylase NagA |
| M. avium 104 | MAV_4307 | nagA | 1e-149 | 71.58% (380) | N-acetylglucosamine-6-phosphate deacetylase |
| M. smegmatis MC2 155 | MSMEG_2119 | nagA | 1e-111 | 55.91% (381) | N-acetylglucosamine-6-phosphate deacetylase |
| M. thermoresistible (build 8) | TH_2020 | - | 4e-05 | 33.33% (144) | amidohydrolase |
| M. ulcerans Agy99 | MUL_1443 | nagA | 1e-147 | 69.85% (388) | n-acetylglucosamine-6-phosphate deacetylase NagA |
| M. vanbaalenii PYR-1 | Mvan_4215 | - | 4e-05 | 32.84% (134) | amidohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3365|M.bovis_AF2122/97 ---MTVLGADAVVIDG-RICRPGWVHTADGRILSGGAGAPPMPADAEFPD
Rv3332|M.tuberculosis_H37Rv ---MTVLGADAVVIDG-RICRPGWVHTADGRILSGGAGAPPMPADAEFPD
MMAR_1190|M.marinum_M ---MTLICAGSVVIDG-ELCRPGWIRTAGHKIADCGTGTAPL-ADFDFPD
MUL_1443|M.ulcerans_Agy99 ---MTLICAGSVVIDG-ELCRPGWIRTAGHKIADCGTGTAPL-ADFDFPD
MAV_4307|M.avium_104 ---MGLIAAGTMVASG-RVHRPGWVETSGGHIAACGTGPPPRPADREFPD
MAB_0362c|M.abscessus_ATCC_199 -------------------------------------------------M
MSMEG_2119|M.smegmatis_MC2_155 ----MLLTADTVLTGT-ELLRPGWLEIASDRVVAVGAGAPPAQADRNLGA
Mflv_2437|M.gilvum_PYR-GCK MPLTTLKAAGLLDVDAGEIIRPGIVHVDGDRIVSIGGDAPPDAEVIDLGD
Mvan_4215|M.vanbaalenii_PYR-1 --MLTLKAAGLLDVVSGEIIRPGVVTVDGDRIVSLGGTPPPDVEVIDLGD
TH_2020|M.thermoresistible__bu --VLTLRAAGLLDVDAGEIVRPGLVRIVDDRIVGVGG--PEGGHVIDLGD
Mb3365|M.bovis_AF2122/97 AIVVPGFVDMHV---HGGGGASFADGNAAD--IARAAEFHLRHGTTTTLA
Rv3332|M.tuberculosis_H37Rv AIVVPGFVDMHV---HGGGGASFADGNAAD--IARAAEFHLRHGTTTTLA
MMAR_1190|M.marinum_M SIVVPGFVDIHV---HGGAGASFADADAGGRALIQASEFHLRHGTTTMLA
MUL_1443|M.ulcerans_Agy99 SIVVPGFVDIHV---HGGAGASFADADAGGRALIQASEFHLRHGTTTMLA
MAV_4307|M.avium_104 GTAVPGFVDMHV---HGGGGASYTD--PDG--IAKAAAFHLRHGTTTTMA
MAB_0362c|M.abscessus_ATCC_199 SVTAPGFFDMHV---HGGGGASFGRDAEAN---LVAATWHRSHGTDGLLA
MSMEG_2119|M.smegmatis_MC2_155 ATVVPGFVDTHL---HGGGGGNFSAATDDET--ARAVALHRAHGSTTLVA
Mflv_2437|M.gilvum_PYR-GCK AILMPGLMDMEVNLLMGGRGETPGLSQVQDD-PATRVLRAVGNARRTLRA
Mvan_4215|M.vanbaalenii_PYR-1 SILLPGLMDMEVNLLMGGRGENPGLSQVQDD-PATRVLRAVGNARRTLRA
TH_2020|M.thermoresistible__bu AILLPGLMDMEVNLLMGGRGETPGLSQVQDD-PATRVLRAVGNARRTLRA
. **:.* .: ** * . :. *
Mb3365|M.bovis_AF2122/97 SLVTAGPAELLSAVGALAEAT---RDGVVAGIHLEGPWLSPA------RC
Rv3332|M.tuberculosis_H37Rv SLVTAGPAELLSAVGALAEAT---RDGVVAGIHLEGPWLSPA------RC
MMAR_1190|M.marinum_M SLVTAAPAQLLSAVAKLAEAISSGRSGTIAGIHLEGPWLSPA------RC
MUL_1443|M.ulcerans_Agy99 SLVTAAPAQLLSAVAKLAEAISSGRSGTIAGIHLEGPWLSPA------RC
MAV_4307|M.avium_104 SLVTGSPAELLGGVRALAEAT---RDRTVAGIHLEGPWLSRA------RC
MAB_0362c|M.abscessus_ATCC_199 SLVTLAPDDLLRAVRVLAEMT---GAEGIAGIHLEGPWLSPQ------YA
MSMEG_2119|M.smegmatis_MC2_155 SLVTAGPEDLLRQVSGLARQV---RAGLIDGIHLEGPWLSTL------RC
Mflv_2437|M.gilvum_PYR-GCK GFTTVRNLGLFVKTGGYLLDVA--LGKAIAAGWIDGPRVIPAGHAITPTG
Mvan_4215|M.vanbaalenii_PYR-1 GFTTVRNLGLFVKTGGYLLDVA--LGKAIDAGWIDGPRVIPAGHAITPTG
TH_2020|M.thermoresistible__bu GFTTVRNLGLFVKTGGYLLDVA--LGKAIDAGWIEGPRVVPAGHAITPTG
.:.* *: . : . ::** :
Mb3365|M.bovis_AF2122/97 GAHDHTRMRAPDPAEIESVLAAADG-AVRMVTLAP--ELPGSDAAIRRFR
Rv3332|M.tuberculosis_H37Rv GAHDHTRMRAPDPAEIESVLAAADG-AVRMVTLAP--ELPGSDAAIRRFR
MMAR_1190|M.marinum_M GAHDHTQVRAPDPAEIDALLAAANG-TIRMVTLAP--ELPGSADTIRRFL
MUL_1443|M.ulcerans_Agy99 GAHDHTQVRAPDPAEIDALLAAANG-TIRMVTLAP--ELPGSADTIRRFL
MAV_4307|M.avium_104 GAHDARRMRDPDPHEIDAVLSAGGG-AIRMVTLAP--ELPGADAAIRRFV
MAB_0362c|M.abscessus_ATCC_199 GAHDPRLLREPDLGELERLLDAGGG-HIKMVTIAP--ELPGAISAIEMLS
MSMEG_2119|M.smegmatis_MC2_155 GAHQPVLMRDPDPGEIGRVLDAGEG-TVRMVTIAP--ERDGALAAIAQLV
Mflv_2437|M.gilvum_PYR-GCK GHLDPTMFAAFMPGVLELTIEEGIANGVDEIRKAVRYQIKHGAELIKVCC
Mvan_4215|M.vanbaalenii_PYR-1 GHLDPTMFAAFMPGVLELTVEEGIANGVDEIRKAVRYQIKHGAQLIKVCC
TH_2020|M.thermoresistible__bu GHLDPTMFAAFMPGALELTVEEGIANGVDEIRKAVRYQIKHGAQVIKVCC
* : . : : . . : : * : . *
Mb3365|M.bovis_AF2122/97 DAEVVVAVGHTDATYTQTR-------HAIDLGATVGTHLFNAMPPLDHRA
Rv3332|M.tuberculosis_H37Rv DAEVVVAVGHTDATYTQTR-------HAIDLGATVGTHLFNAMPPLDHRA
MMAR_1190|M.marinum_M AADVVVALGHTDATYEQTC-------QAIGHGATVATHLFNAMAPLGHRE
MUL_1443|M.ulcerans_Agy99 AAGVVVALGHSDATYEQTC-------QAIGHGATVATHLFNAMAPLGHRE
MAV_4307|M.avium_104 DAGVVVAVGHTNADYRQTR-------HAIALGATVGTHLFNAMPPLHHRE
MAB_0362c|M.abscessus_ATCC_199 GRGVVAAVGHTNATYEQTQ-------QAISAGATVATHLFNAMRPIHHRE
MSMEG_2119|M.smegmatis_MC2_155 NAGVVAAVGHTEATYDQTR-------AAIDAGATVGTHLFNAMRPIDRRE
Mflv_2437|M.gilvum_PYR-GCK SGGVMSLTGEAGAQHYSDEELRVIVDEAHRRGLRVAAHTHGAEAVKHAID
Mvan_4215|M.vanbaalenii_PYR-1 SGGVMSLTGEAGAQHYSDEELRVIVDEAHRRGLRVAAHTHGAEAVKHAVE
TH_2020|M.thermoresistible__bu SGGVMSLTGEAGAQHYSDEELRAIVDEAHRRGLKVAAHTHGAEAVKHAIE
*: *.: * : . * * *.:* ..*
Mb3365|M.bovis_AF2122/97 PGPVLALLCDPRVTVEIIADGVHVHPAVVHAVIEAVGPDRVAVVTDAIAA
Rv3332|M.tuberculosis_H37Rv PGPVLALLCDPRVTVEIIADGVHVHPAVVHAVIEAVGPDRVAVVTDAIAA
MMAR_1190|M.marinum_M PGPALALLKDPAVTLELIADGVHVHPAVVAAVIEAVGPDRVALVTDAIAA
MUL_1443|M.ulcerans_Agy99 PGPALALLKDPAVTLELIADGVHVHPAVVAAVIEAVGPDRVALVTDAIAA
MAV_4307|M.avium_104 PGPALALLRDPRVTVELIADGVHVHPDVVHAVIDAAGPERVALVTDALAA
MAB_0362c|M.abscessus_ATCC_199 PGPIPALLESPDVTIELIADGVHIHPAIYRTVLAAVGPDRIALVTDAMCA
MSMEG_2119|M.smegmatis_MC2_155 PGPAVALTEDSRVTVEMIVDGVHVAPAIYRHITQTVGPERLSLITDAMAA
Mflv_2437|M.gilvum_PYR-GCK CG--IDCIEHGFLMDDEAIQMLVDNDRFLVSTRRLAEYMDVSKAPKELQA
Mvan_4215|M.vanbaalenii_PYR-1 CG--IDCIEHGFLMDDEAIQMLVDNDRFLVSTRRLAEYMDVSKAPPELQA
TH_2020|M.thermoresistible__bu CG--IDCIEHGFLMDDEAIKMLVDNDRFLVSTRRLAEYMDVSKAPPELQA
* : : . : . . :: . : *
Mb3365|M.bovis_AF2122/97 AGCGDGAFRLGTMPIEVESSVARVAGASTLAGST-TTMDQLFRTVAGLGS
Rv3332|M.tuberculosis_H37Rv AGCGDGAFRLGTMPIEVESSVARVAGASTLAGST-TTMDQLFRTVAGLGS
MMAR_1190|M.marinum_M AGCGDGTYRLGSVPIEVESNVARVCGTPTIAGST-ATMDRLFRAAFRAG-
MUL_1443|M.ulcerans_Agy99 AGCGDGTYRLGSVPIEVESNVARVCGTPTIAGST-ATMDRLFRAAFRAG-
MAV_4307|M.avium_104 AGRPDGAFRLGPVHIDVVAGVARVHGTTTIAGST-ATMDRLFRTVAGSG-
MAB_0362c|M.abscessus_ATCC_199 AGMPDGAYQLGDLPVTVAGGEARLP-NGTIAGST-ASMADLHRFAAAQAG
MSMEG_2119|M.smegmatis_MC2_155 TGMSDGVYRLGPLDIDVVAGVARVAGTDTIAGST-ATMEQVFRLAVAHCG
Mflv_2437|M.gilvum_PYR-GCK KAAEMFPKARTSIKAAYEAGVKIAVGTDAPAIPHGKNADELVTLVDWGMP
Mvan_4215|M.vanbaalenii_PYR-1 KAAEMFPKARTSIKAAYEAGVKIAVGTDAPAIPHGKNADELVTLVDWGMP
TH_2020|M.thermoresistible__bu KAAEMFPRARTSIKAAFEAGAKIAVGTDAPAIPHGRNAEELVTLVQWGLP
. : .. : * . . : .
Mb3365|M.bovis_AF2122/97 KSDSAGDVALAAAVQVTSATPARALGLTGVGRLAAGYAANLVVLDRDLRV
Rv3332|M.tuberculosis_H37Rv KSDSAGDVALAAAVQVTSATPARALGLTGVGRLAAGYAANLVVLDRDLRV
MMAR_1190|M.marinum_M PGAALDAGALAAAVQMTSATPARAVGLARRGSLRAGFDANLVVLDRDLRV
MUL_1443|M.ulcerans_Agy99 AGAALDAGALAAAVQMTSATPARAVGLARRGSLRAGFDANLVVLDRDLRV
MAV_4307|M.avium_104 ---TDRDAALAAAVQMTSTTPARALGLDRVGSLRAGHEANLVVLDDDWRV
MAB_0362c|M.abscessus_ATCC_199 ---T------DIATRQTSVNPRRAVGC-----------------------
MSMEG_2119|M.smegmatis_MC2_155 ---LPRDDALSLAVRQACVNPARALGLPAAG-LAAGARADLVVLDHDLAV
Mflv_2437|M.gilvum_PYR-GCK EAAVLRAATVVAADLINRSDSLGRLAEGYIADIIAVPGDPLADIRVTQAV
Mvan_4215|M.vanbaalenii_PYR-1 PAAVLRAATVVAADLINRSDSLGRIAEGYLADIIAVPGDPLADIGVTKNV
TH_2020|M.thermoresistible__bu PAAVLRAATVTAADLIGRSD-LGRIAEGCLADIVAVPGDPLADIGVTREV
* :.
Mb3365|M.bovis_AF2122/97 TAVMVNDDWRVG-------
Rv3332|M.tuberculosis_H37Rv TAVMVNDDWRVG-------
MMAR_1190|M.marinum_M AAVMANGEWQAVED-----
MUL_1443|M.ulcerans_Agy99 AAVMANGEWQAVED-----
MAV_4307|M.avium_104 RAVMVRGDWLADP------
MAB_0362c|M.abscessus_ATCC_199 -------------------
MSMEG_2119|M.smegmatis_MC2_155 TAVMRAGEWVVTPGAAHTV
Mflv_2437|M.gilvum_PYR-GCK NFVMKDGKVFKNDVTH---
Mvan_4215|M.vanbaalenii_PYR-1 TFVMKGGKVYKNEHATDTN
TH_2020|M.thermoresistible__bu NFVMKGGEVFRHDAN----