For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_1190 (nagA)

annotation: N-acetylglucosamine-6-phosphate deacetylase NagA
coordinates: 1439988 - 1441154
length: 388

TLICAGSVVIDGELCRPGWIRTAGHKIADCGTGTAPLADFDFPDSIVVPGFVDIHVHGGAGASFADADAG
GRALIQASEFHLRHGTTTMLASLVTAAPAQLLSAVAKLAEAISSGRSGTIAGIHLEGPWLSPARCGAHDH
TQVRAPDPAEIDALLAAANGTIRMVTLAPELPGSADTIRRFLAADVVVALGHTDATYEQTCQAIGHGATV
ATHLFNAMAPLGHREPGPALALLKDPAVTLELIADGVHVHPAVVAAVIEAVGPDRVALVTDAIAAAGCGD
GTYRLGSVPIEVESNVARVCGTPTIAGSTATMDRLFRAAFRAGPGAALDAGALAAAVQMTSATPARAVGL
ARRGSLRAGFDANLVVLDRDLRVAAVMANGEWQAVED*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. marinum M MMAR_1190 nagA - 100% (388) N-acetylglucosamine-6-phosphate deacetylase NagA

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3365 nagA 1e-148 70.36% (388) N-acetylglucosamine-6-phosphate deacetylase
M. gilvum PYR-GCK - - - - -
M. tuberculosis H37Rv Rv3332 nagA 1e-148 70.36% (388) N-acetylglucosamine-6-phosphate deacetylase
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_0362c - 9e-83 56.54% (306) N-acetylglucosamine-6-phosphate deacetylase NagA
M. avium 104 MAV_4307 nagA 1e-135 66.84% (386) N-acetylglucosamine-6-phosphate deacetylase
M. smegmatis MC2 155 MSMEG_2119 nagA 1e-100 52.36% (382) N-acetylglucosamine-6-phosphate deacetylase
M. thermoresistible (build 8) - - - - -
M. ulcerans Agy99 MUL_1443 nagA 0.0 98.97% (388) n-acetylglucosamine-6-phosphate deacetylase NagA
M. vanbaalenii PYR-1 - - - - -

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1190|M.marinum_M               MTLICAGSVVIDGELCRPGWIRTAGHKIADCGTGTAPL-ADFDFPDSIVV
MUL_1443|M.ulcerans_Agy99           MTLICAGSVVIDGELCRPGWIRTAGHKIADCGTGTAPL-ADFDFPDSIVV
Mb3365|M.bovis_AF2122/97            MTVLGADAVVIDGRICRPGWVHTADGRILSGGAGAPPMPADAEFPDAIVV
Rv3332|M.tuberculosis_H37Rv         MTVLGADAVVIDGRICRPGWVHTADGRILSGGAGAPPMPADAEFPDAIVV
MAV_4307|M.avium_104                MGLIAAGTMVASGRVHRPGWVETSGGHIAACGTGPPPRPADREFPDGTAV
MAB_0362c|M.abscessus_ATCC_199      ---------------------------------------------MSVTA
MSMEG_2119|M.smegmatis_MC2_155      -MLLTADTVLTGTELLRPGWLEIASDRVVAVGAGAPPAQADRNLGAATVV
                                                                                  . ..

MMAR_1190|M.marinum_M               PGFVDIHVHGGAGASFADADAGGRALIQASEFHLRHGTTTMLASLVTAAP
MUL_1443|M.ulcerans_Agy99           PGFVDIHVHGGAGASFADADAGGRALIQASEFHLRHGTTTMLASLVTAAP
Mb3365|M.bovis_AF2122/97            PGFVDMHVHGGGGASFADGNAAD--IARAAEFHLRHGTTTTLASLVTAGP
Rv3332|M.tuberculosis_H37Rv         PGFVDMHVHGGGGASFADGNAAD--IARAAEFHLRHGTTTTLASLVTAGP
MAV_4307|M.avium_104                PGFVDMHVHGGGGASYTD--PDG--IAKAAAFHLRHGTTTTMASLVTGSP
MAB_0362c|M.abscessus_ATCC_199      PGFFDMHVHGGGGASFGRDAEAN---LVAATWHRSHGTDGLLASLVTLAP
MSMEG_2119|M.smegmatis_MC2_155      PGFVDTHLHGGGGGNFSAATDDET--ARAVALHRAHGSTTLVASLVTAGP
                                    ***.* *:***.*..:            *   *  **:   :***** .*

MMAR_1190|M.marinum_M               AQLLSAVAKLAEAISSGRSGTIAGIHLEGPWLSPARCGAHDHTQVRAPDP
MUL_1443|M.ulcerans_Agy99           AQLLSAVAKLAEAISSGRSGTIAGIHLEGPWLSPARCGAHDHTQVRAPDP
Mb3365|M.bovis_AF2122/97            AELLSAVGALAEAT---RDGVVAGIHLEGPWLSPARCGAHDHTRMRAPDP
Rv3332|M.tuberculosis_H37Rv         AELLSAVGALAEAT---RDGVVAGIHLEGPWLSPARCGAHDHTRMRAPDP
MAV_4307|M.avium_104                AELLGGVRALAEAT---RDRTVAGIHLEGPWLSRARCGAHDARRMRDPDP
MAB_0362c|M.abscessus_ATCC_199      DDLLRAVRVLAEMT---GAEGIAGIHLEGPWLSPQYAGAHDPRLLREPDL
MSMEG_2119|M.smegmatis_MC2_155      EDLLRQVSGLARQV---RAGLIDGIHLEGPWLSTLRCGAHQPVLMRDPDP
                                     :**  *  **.         : **********   .***:   :* ** 

MMAR_1190|M.marinum_M               AEIDALLAAANGTIRMVTLAPELPGSADTIRRFLAADVVVALGHTDATYE
MUL_1443|M.ulcerans_Agy99           AEIDALLAAANGTIRMVTLAPELPGSADTIRRFLAAGVVVALGHSDATYE
Mb3365|M.bovis_AF2122/97            AEIESVLAAADGAVRMVTLAPELPGSDAAIRRFRDAEVVVAVGHTDATYT
Rv3332|M.tuberculosis_H37Rv         AEIESVLAAADGAVRMVTLAPELPGSDAAIRRFRDAEVVVAVGHTDATYT
MAV_4307|M.avium_104                HEIDAVLSAGGGAIRMVTLAPELPGADAAIRRFVDAGVVVAVGHTNADYR
MAB_0362c|M.abscessus_ATCC_199      GELERLLDAGGGHIKMVTIAPELPGAISAIEMLSGRGVVAAVGHTNATYE
MSMEG_2119|M.smegmatis_MC2_155      GEIGRVLDAGEGTVRMVTIAPERDGALAAIAQLVNAGVVAAVGHTEATYD
                                     *:  :* *. * ::***:***  *:  :*  :    **.*:**::* * 

MMAR_1190|M.marinum_M               QTCQAIGHGATVATHLFNAMAPLGHREPGPALALLKDPAVTLELIADGVH
MUL_1443|M.ulcerans_Agy99           QTCQAIGHGATVATHLFNAMAPLGHREPGPALALLKDPAVTLELIADGVH
Mb3365|M.bovis_AF2122/97            QTRHAIDLGATVGTHLFNAMPPLDHRAPGPVLALLCDPRVTVEIIADGVH
Rv3332|M.tuberculosis_H37Rv         QTRHAIDLGATVGTHLFNAMPPLDHRAPGPVLALLCDPRVTVEIIADGVH
MAV_4307|M.avium_104                QTRHAIALGATVGTHLFNAMPPLHHREPGPALALLRDPRVTVELIADGVH
MAB_0362c|M.abscessus_ATCC_199      QTQQAISAGATVATHLFNAMRPIHHREPGPIPALLESPDVTIELIADGVH
MSMEG_2119|M.smegmatis_MC2_155      QTRAAIDAGATVGTHLFNAMRPIDRREPGPAVALTEDSRVTVEMIVDGVH
                                    **  **  ****.******* *: :* ***  **  .. **:*:*.****

MMAR_1190|M.marinum_M               VHPAVVAAVIEAVGPDRVALVTDAIAAAGCGDGTYRLGSVPIEVESNVAR
MUL_1443|M.ulcerans_Agy99           VHPAVVAAVIEAVGPDRVALVTDAIAAAGCGDGTYRLGSVPIEVESNVAR
Mb3365|M.bovis_AF2122/97            VHPAVVHAVIEAVGPDRVAVVTDAIAAAGCGDGAFRLGTMPIEVESSVAR
Rv3332|M.tuberculosis_H37Rv         VHPAVVHAVIEAVGPDRVAVVTDAIAAAGCGDGAFRLGTMPIEVESSVAR
MAV_4307|M.avium_104                VHPDVVHAVIDAAGPERVALVTDALAAAGRPDGAFRLGPVHIDVVAGVAR
MAB_0362c|M.abscessus_ATCC_199      IHPAIYRTVLAAVGPDRIALVTDAMCAAGMPDGAYQLGDLPVTVAGGEAR
MSMEG_2119|M.smegmatis_MC2_155      VAPAIYRHITQTVGPERLSLITDAMAATGMSDGVYRLGPLDIDVVAGVAR
                                    : * :   :  :.**:*::::***:.*:*  **.::** : : * .. **

MMAR_1190|M.marinum_M               VCGTPTIAGSTATMDRLFR-AAFRAGPG-AALDAGALAAAVQMTSATPAR
MUL_1443|M.ulcerans_Agy99           VCGTPTIAGSTATMDRLFR-AAFRAGAG-AALDAGALAAAVQMTSATPAR
Mb3365|M.bovis_AF2122/97            VAGASTLAGSTTTMDQLFR-TVAGLGSKSDSAGDVALAAAVQVTSATPAR
Rv3332|M.tuberculosis_H37Rv         VAGASTLAGSTTTMDQLFR-TVAGLGSKSDSAGDVALAAAVQVTSATPAR
MAV_4307|M.avium_104                VHGTTTIAGSTATMDRLFR-TVAGSGTD----RDAALAAAVQMTSTTPAR
MAB_0362c|M.abscessus_ATCC_199      LP-NGTIAGSTASMADLHRFAAAQAGT----------DIATRQTSVNPRR
MSMEG_2119|M.smegmatis_MC2_155      VAGTDTIAGSTATMEQVFRLAVAHCGLP----RDDALSLAVRQACVNPAR
                                    :    *:****::*  :.* :.   *             *.: :...* *

MMAR_1190|M.marinum_M               AVGLARRGSLRAGFDANLVVLDRDLRVAAVMANGEWQAVED-----
MUL_1443|M.ulcerans_Agy99           AVGLARRGSLRAGFDANLVVLDRDLRVAAVMANGEWQAVED-----
Mb3365|M.bovis_AF2122/97            ALGLTGVGRLAAGYAANLVVLDRDLRVTAVMVNDDWRVG-------
Rv3332|M.tuberculosis_H37Rv         ALGLTGVGRLAAGYAANLVVLDRDLRVTAVMVNDDWRVG-------
MAV_4307|M.avium_104                ALGLDRVGSLRAGHEANLVVLDDDWRVRAVMVRGDWLADP------
MAB_0362c|M.abscessus_ATCC_199      AVGC------------------------------------------
MSMEG_2119|M.smegmatis_MC2_155      ALGLPAAG-LAAGARADLVVLDHDLAVTAVMRAGEWVVTPGAAHTV
                                    *:*

species	id	gene	e-value	identity (len)	annotation
M. marinum M	MMAR_1190	nagA	-	100% (388)	N-acetylglucosamine-6-phosphate deacetylase NagA