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M. avium 104 MAV_4307 (nagA)

annotation: N-acetylglucosamine-6-phosphate deacetylase
coordinates: 4437751 - 4438887
length: 378

VGLIAAGTMVASGRVHRPGWVETSGGHIAACGTGPPPRPADREFPDGTAVPGFVDMHVHGGGGASYTDPD
GIAKAAAFHLRHGTTTTMASLVTGSPAELLGGVRALAEATRDRTVAGIHLEGPWLSRARCGAHDARRMRD
PDPHEIDAVLSAGGGAIRMVTLAPELPGADAAIRRFVDAGVVVAVGHTNADYRQTRHAIALGATVGTHLF
NAMPPLHHREPGPALALLRDPRVTVELIADGVHVHPDVVHAVIDAAGPERVALVTDALAAAGRPDGAFRL
GPVHIDVVAGVARVHGTTTIAGSTATMDRLFRTVAGSGTDRDAALAAAVQMTSTTPARALGLDRVGSLRA
GHEANLVVLDDDWRVRAVMVRGDWLADP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4307nagA-100% (378)N-acetylglucosamine-6-phosphate deacetylase
M. avium 104MAV_2355-8e-0530.64% (173) LppL protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3365nagA1e-14971.58% (380) N-acetylglucosamine-6-phosphate deacetylase
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv3332nagA1e-14971.58% (380) N-acetylglucosamine-6-phosphate deacetylase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0362c-2e-8657.34% (293) N-acetylglucosamine-6-phosphate deacetylase NagA
M. marinum MMMAR_1190nagA1e-13566.84% (386) N-acetylglucosamine-6-phosphate deacetylase NagA
M. smegmatis MC2 155MSMEG_2119nagA1e-11356.73% (379) N-acetylglucosamine-6-phosphate deacetylase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1443nagA1e-13566.93% (384) n-acetylglucosamine-6-phosphate deacetylase NagA
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1190|M.marinum_M               MTLICAGSVVIDGELCRPGWIRTAGHKIADCGTGTAPL-ADFDFPDSIVV
MUL_1443|M.ulcerans_Agy99           MTLICAGSVVIDGELCRPGWIRTAGHKIADCGTGTAPL-ADFDFPDSIVV
Mb3365|M.bovis_AF2122/97            MTVLGADAVVIDGRICRPGWVHTADGRILSGGAGAPPMPADAEFPDAIVV
Rv3332|M.tuberculosis_H37Rv         MTVLGADAVVIDGRICRPGWVHTADGRILSGGAGAPPMPADAEFPDAIVV
MAV_4307|M.avium_104                MGLIAAGTMVASGRVHRPGWVETSGGHIAACGTGPPPRPADREFPDGTAV
MAB_0362c|M.abscessus_ATCC_199      ---------------------------------------------MSVTA
MSMEG_2119|M.smegmatis_MC2_155      -MLLTADTVLTGTELLRPGWLEIASDRVVAVGAGAPPAQADRNLGAATVV
                                                                                  . ..

MMAR_1190|M.marinum_M               PGFVDIHVHGGAGASFADADAGGRALIQASEFHLRHGTTTMLASLVTAAP
MUL_1443|M.ulcerans_Agy99           PGFVDIHVHGGAGASFADADAGGRALIQASEFHLRHGTTTMLASLVTAAP
Mb3365|M.bovis_AF2122/97            PGFVDMHVHGGGGASFADGNAAD--IARAAEFHLRHGTTTTLASLVTAGP
Rv3332|M.tuberculosis_H37Rv         PGFVDMHVHGGGGASFADGNAAD--IARAAEFHLRHGTTTTLASLVTAGP
MAV_4307|M.avium_104                PGFVDMHVHGGGGASYTD--PDG--IAKAAAFHLRHGTTTTMASLVTGSP
MAB_0362c|M.abscessus_ATCC_199      PGFFDMHVHGGGGASFGRDAEAN---LVAATWHRSHGTDGLLASLVTLAP
MSMEG_2119|M.smegmatis_MC2_155      PGFVDTHLHGGGGGNFSAATDDET--ARAVALHRAHGSTTLVASLVTAGP
                                    ***.* *:***.*..:            *   *  **:   :***** .*

MMAR_1190|M.marinum_M               AQLLSAVAKLAEAISSGRSGTIAGIHLEGPWLSPARCGAHDHTQVRAPDP
MUL_1443|M.ulcerans_Agy99           AQLLSAVAKLAEAISSGRSGTIAGIHLEGPWLSPARCGAHDHTQVRAPDP
Mb3365|M.bovis_AF2122/97            AELLSAVGALAEAT---RDGVVAGIHLEGPWLSPARCGAHDHTRMRAPDP
Rv3332|M.tuberculosis_H37Rv         AELLSAVGALAEAT---RDGVVAGIHLEGPWLSPARCGAHDHTRMRAPDP
MAV_4307|M.avium_104                AELLGGVRALAEAT---RDRTVAGIHLEGPWLSRARCGAHDARRMRDPDP
MAB_0362c|M.abscessus_ATCC_199      DDLLRAVRVLAEMT---GAEGIAGIHLEGPWLSPQYAGAHDPRLLREPDL
MSMEG_2119|M.smegmatis_MC2_155      EDLLRQVSGLARQV---RAGLIDGIHLEGPWLSTLRCGAHQPVLMRDPDP
                                     :**  *  **.         : **********   .***:   :* ** 

MMAR_1190|M.marinum_M               AEIDALLAAANGTIRMVTLAPELPGSADTIRRFLAADVVVALGHTDATYE
MUL_1443|M.ulcerans_Agy99           AEIDALLAAANGTIRMVTLAPELPGSADTIRRFLAAGVVVALGHSDATYE
Mb3365|M.bovis_AF2122/97            AEIESVLAAADGAVRMVTLAPELPGSDAAIRRFRDAEVVVAVGHTDATYT
Rv3332|M.tuberculosis_H37Rv         AEIESVLAAADGAVRMVTLAPELPGSDAAIRRFRDAEVVVAVGHTDATYT
MAV_4307|M.avium_104                HEIDAVLSAGGGAIRMVTLAPELPGADAAIRRFVDAGVVVAVGHTNADYR
MAB_0362c|M.abscessus_ATCC_199      GELERLLDAGGGHIKMVTIAPELPGAISAIEMLSGRGVVAAVGHTNATYE
MSMEG_2119|M.smegmatis_MC2_155      GEIGRVLDAGEGTVRMVTIAPERDGALAAIAQLVNAGVVAAVGHTEATYD
                                     *:  :* *. * ::***:***  *:  :*  :    **.*:**::* * 

MMAR_1190|M.marinum_M               QTCQAIGHGATVATHLFNAMAPLGHREPGPALALLKDPAVTLELIADGVH
MUL_1443|M.ulcerans_Agy99           QTCQAIGHGATVATHLFNAMAPLGHREPGPALALLKDPAVTLELIADGVH
Mb3365|M.bovis_AF2122/97            QTRHAIDLGATVGTHLFNAMPPLDHRAPGPVLALLCDPRVTVEIIADGVH
Rv3332|M.tuberculosis_H37Rv         QTRHAIDLGATVGTHLFNAMPPLDHRAPGPVLALLCDPRVTVEIIADGVH
MAV_4307|M.avium_104                QTRHAIALGATVGTHLFNAMPPLHHREPGPALALLRDPRVTVELIADGVH
MAB_0362c|M.abscessus_ATCC_199      QTQQAISAGATVATHLFNAMRPIHHREPGPIPALLESPDVTIELIADGVH
MSMEG_2119|M.smegmatis_MC2_155      QTRAAIDAGATVGTHLFNAMRPIDRREPGPAVALTEDSRVTVEMIVDGVH
                                    **  **  ****.******* *: :* ***  **  .. **:*:*.****

MMAR_1190|M.marinum_M               VHPAVVAAVIEAVGPDRVALVTDAIAAAGCGDGTYRLGSVPIEVESNVAR
MUL_1443|M.ulcerans_Agy99           VHPAVVAAVIEAVGPDRVALVTDAIAAAGCGDGTYRLGSVPIEVESNVAR
Mb3365|M.bovis_AF2122/97            VHPAVVHAVIEAVGPDRVAVVTDAIAAAGCGDGAFRLGTMPIEVESSVAR
Rv3332|M.tuberculosis_H37Rv         VHPAVVHAVIEAVGPDRVAVVTDAIAAAGCGDGAFRLGTMPIEVESSVAR
MAV_4307|M.avium_104                VHPDVVHAVIDAAGPERVALVTDALAAAGRPDGAFRLGPVHIDVVAGVAR
MAB_0362c|M.abscessus_ATCC_199      IHPAIYRTVLAAVGPDRIALVTDAMCAAGMPDGAYQLGDLPVTVAGGEAR
MSMEG_2119|M.smegmatis_MC2_155      VAPAIYRHITQTVGPERLSLITDAMAATGMSDGVYRLGPLDIDVVAGVAR
                                    : * :   :  :.**:*::::***:.*:*  **.::** : : * .. **

MMAR_1190|M.marinum_M               VCGTPTIAGSTATMDRLFR-AAFRAGPG-AALDAGALAAAVQMTSATPAR
MUL_1443|M.ulcerans_Agy99           VCGTPTIAGSTATMDRLFR-AAFRAGAG-AALDAGALAAAVQMTSATPAR
Mb3365|M.bovis_AF2122/97            VAGASTLAGSTTTMDQLFR-TVAGLGSKSDSAGDVALAAAVQVTSATPAR
Rv3332|M.tuberculosis_H37Rv         VAGASTLAGSTTTMDQLFR-TVAGLGSKSDSAGDVALAAAVQVTSATPAR
MAV_4307|M.avium_104                VHGTTTIAGSTATMDRLFR-TVAGSGTD----RDAALAAAVQMTSTTPAR
MAB_0362c|M.abscessus_ATCC_199      LP-NGTIAGSTASMADLHRFAAAQAGT----------DIATRQTSVNPRR
MSMEG_2119|M.smegmatis_MC2_155      VAGTDTIAGSTATMEQVFRLAVAHCGLP----RDDALSLAVRQACVNPAR
                                    :    *:****::*  :.* :.   *             *.: :...* *

MMAR_1190|M.marinum_M               AVGLARRGSLRAGFDANLVVLDRDLRVAAVMANGEWQAVED-----
MUL_1443|M.ulcerans_Agy99           AVGLARRGSLRAGFDANLVVLDRDLRVAAVMANGEWQAVED-----
Mb3365|M.bovis_AF2122/97            ALGLTGVGRLAAGYAANLVVLDRDLRVTAVMVNDDWRVG-------
Rv3332|M.tuberculosis_H37Rv         ALGLTGVGRLAAGYAANLVVLDRDLRVTAVMVNDDWRVG-------
MAV_4307|M.avium_104                ALGLDRVGSLRAGHEANLVVLDDDWRVRAVMVRGDWLADP------
MAB_0362c|M.abscessus_ATCC_199      AVGC------------------------------------------
MSMEG_2119|M.smegmatis_MC2_155      ALGLPAAG-LAAGARADLVVLDHDLAVTAVMRAGEWVVTPGAAHTV
                                    *:*