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TPLIDSFGRIATDLRVSLTDRCNLRCTYCMPAEGLDWLRSETLLTTDEYIRLIGIAVTRLGIDSVRFTGG EPLIFKDLEKLVAAVAGMSPRPDIAVTTNGVGLDRKAVALREAGLDRINVSLDTLDAHRFAAITRRDRLS DVLLGLKAAGSAGLSPIKINAVLTPEQYKEDAVALLHFSLEHGYELRIIEQMPLDAGHSWSRARMVTADE IHAALSREFSLSEDPAPRGSAPAQRWLVNGGPATVGIIASVSRPFCGDCDRTRLTADGQVRNCLFATTET DLRGLLRSGASDAEVASAWQAAMWGKKPGHGINDPSFLQPDRPMSAIGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0871c | moaA | - | 100% (330) | molybdenum cofactor biosynthesis protein A |
| M. abscessus ATCC 19977 | MAB_3835c | - | 5e-07 | 26.75% (228) | coenzyme PQQ synthesis protein E PqqE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0893c | moaA | 1e-125 | 66.27% (332) | molybdenum cofactor biosynthesis protein A |
| M. gilvum PYR-GCK | Mflv_1705 | moaA | 1e-127 | 67.67% (331) | molybdenum cofactor biosynthesis protein A |
| M. tuberculosis H37Rv | Rv0869c | moaA | 1e-125 | 66.27% (332) | molybdenum cofactor biosynthesis protein A |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4663 | moaA | 1e-126 | 66.57% (332) | molybdenum cofactor biosynthesis protein A2 MoaA2 |
| M. avium 104 | MAV_4478 | - | 5e-05 | 27.01% (211) | radical SAM domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5698 | moaA | 1e-124 | 65.06% (332) | molybdenum cofactor biosynthesis protein A |
| M. thermoresistible (build 8) | TH_1071 | moaA | 1e-132 | 69.82% (328) | molybdenum cofactor biosynthesis protein A |
| M. ulcerans Agy99 | MUL_0281 | moaA | 1e-125 | 66.27% (332) | molybdenum cofactor biosynthesis protein A |
| M. vanbaalenii PYR-1 | Mvan_5047 | moaA | 1e-130 | 68.88% (331) | molybdenum cofactor biosynthesis protein A |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0893c|M.bovis_AF2122/97 MTLTALGMPALRSRTNG-IADPRVVPTTGPLVDTFGR---VANDLRVSLT
Rv0869c|M.tuberculosis_H37Rv MTLTALGMPALRSRTNG-IADPRVVPTTGPLVDTFGR---VANDLRVSLT
MMAR_4663|M.marinum_M MTVTALGVPTVRGRSEG-SAIASDAPGDGPLLDRFGR---SATDLRVSLT
MUL_0281|M.ulcerans_Agy99 MTVTALGVPTVRGRSEG-SAVASDAPGDGPLLDRFGR---SATDLRVSLT
TH_1071|M.thermoresistible__bu MTVTALGLPAVRRPSP-----PSAPPASGPLVDTFGR---VHTDLRISLT
Mflv_1705|M.gilvum_PYR-GCK MTVVPLGLPSVQRPS-------TPAPATGPLIDTFGR---VATDLRVSLT
Mvan_5047|M.vanbaalenii_PYR-1 MTVVALGVPSVHRPQ-------SPAPEEGPLVDTFGR---VATDLRVSLT
MSMEG_5698|M.smegmatis_MC2_155 MTVTALGLPTVARSTGDGSAGASPAPADGPLVDTYGR---AATDLRVSLT
MAB_0871c|M.abscessus_ATCC_199 ---------------------------MTPLIDSFGR---IATDLRVSLT
MAV_4478|M.avium_104 ---------------------MTTAAPVPRLIEQFEHGLDAPICLTWELT
*:: : : * .**
Mb0893c|M.bovis_AF2122/97 DRCNLRCSYCMPERGLRWLPGEQLLRPDELARLIHIAVTRLGVTSVRFTG
Rv0869c|M.tuberculosis_H37Rv DRCNLRCSYCMPERGLRWLPGEQLLRPDELARLIHIAVTRLGVTSVRFTG
MMAR_4663|M.marinum_M DRCNLRCGYCMPAEGLNWLPGEQLLGPAELARLLRIAVTRLGITSVRFTG
MUL_0281|M.ulcerans_Agy99 DRCNLRCGYCMPAEGLNWLPGEQLLGPAELARLPRIAVTPLGITSVRFTG
TH_1071|M.thermoresistible__bu DRCNLRCTYCMPAEGLDWLPGEHLLRPDELARLLHIAVTRLGITNVRFTG
Mflv_1705|M.gilvum_PYR-GCK DLCNLRCTYCMPAEGLDWMPRDQKLTPDELTRLLRIGVTRLGITSIRFTG
Mvan_5047|M.vanbaalenii_PYR-1 DLCNLRCTYCMPAEGLDWLPSDEKLNPDELIRLLGVAVTRLGITSVRFTG
MSMEG_5698|M.smegmatis_MC2_155 DRCNLRCTYCMPAEGLNWLPGDALLSPTELARLLRIAVARLGITSVRFTG
MAB_0871c|M.abscessus_ATCC_199 DRCNLRCTYCMPAEGLDWLRSETLLTTDEYIRLIGIAVTRLGIDSVRFTG
MAV_4478|M.avium_104 YACNLACVHCLSSSGK---RDPRELSTRQCMDIID-ELERMQVFYVNIGG
*** * :*:. * * . : : : : : :.: *
Mb0893c|M.bovis_AF2122/97 GEPLLAHHLDEVVAATARLRPRPEISLTTNGVGLARRAGA-LAEAGLDRV
Rv0869c|M.tuberculosis_H37Rv GEPLLAHHLDEVVAATARLRPRPEISLTTNGVGLARRAGA-LAEAGLDRV
MMAR_4663|M.marinum_M GEPLLARHLEEVVAAAAQLRPRPEISLTTNGVGLAKRAAA-LAEAGLDRV
MUL_0281|M.ulcerans_Agy99 GEPLLARHLEEVVAAAAQLRPRPEISLTTNGVGLAKRAAA-LAEAGLDRV
TH_1071|M.thermoresistible__bu GEPLVARHLEEVVAAAAAERPRPEIALTTNGIGLAKRARR-LKDAGLDRV
Mflv_1705|M.gilvum_PYR-GCK GEPLVVPHLEDVLAATTALQPRPEITLTTNGIGLAQRAAG-LRRAGLNRI
Mvan_5047|M.vanbaalenii_PYR-1 GEPLVVPHLEDVVAATAALRPRPEITLTTNGVGLAKRAAG-LKRAGLDRI
MSMEG_5698|M.smegmatis_MC2_155 GEPLVVRHLEEVVAAAAALEPRPEITLTTNGLGLARRAEG-LKKAGLNRI
MAB_0871c|M.abscessus_ATCC_199 GEPLIFKDLEKLVAAVAGMSPRPDIAVTTNGVGLDRKAVA-LREAGLDRI
MAV_4478|M.avium_104 GEPTVRPDFWELVDYATAHHVG--VKFSTNGVRITPEVAARLAASDYVDV
*** : .: .:: .: : .:***: : .. * :. :
Mb0893c|M.bovis_AF2122/97 NVSLDSIDRAHFAAITRRDRLAHVLAGLAAAKAAGLTP---VKVNAVLDP
Rv0869c|M.tuberculosis_H37Rv NVSLDSIDRAHFAAITRRDRLAHVLAGLAAAKAAGLTP---VKVNAVLDP
MMAR_4663|M.marinum_M NVSLDTVDRAHFAAITRRDRLTDVLDGLAGARAAGLTP---VKVNAVLDP
MUL_0281|M.ulcerans_Agy99 NVSLDTVDRAHFAAVTRRDRLTDVLDGLAGARAAGLTP---VKVNAVLDP
TH_1071|M.thermoresistible__bu NVSLDTVDPVRFARITRRDRLADVLAGLEAARAAGLTP---VKVNAVLDA
Mflv_1705|M.gilvum_PYR-GCK NVSLDTVDPARFAAITRRDRFDDVIAGLHAAKEAGLQP---VKVNAVLDP
Mvan_5047|M.vanbaalenii_PYR-1 NVSLDTVDPARFAAITRRDRFTEVVAGLRAAKEAGLDP---VKVNAVLDP
MSMEG_5698|M.smegmatis_MC2_155 NVSLDSVDAAHFARITRRDRLPDVLAGLAAAKAAGLEP---VKVNAVLDP
MAB_0871c|M.abscessus_ATCC_199 NVSLDTLDAHRFAAITRRDRLSDVLLGLKAAGSAGLSP---IKINAVLTP
MAV_4478|M.avium_104 QISLDGATAEVNDAVRGPGSFDMAVRALQNLADAGFTQNGGAKISVVVTR
::*** : . : .: .* **: *:..*:
Mb0893c|M.bovis_AF2122/97 TTGREDVVDLLRFCLERGYQLRVIEQMPLDAGHSWRRNIALSADDVLAAL
Rv0869c|M.tuberculosis_H37Rv TTGREDVVDLLRFCLERGYQLRVIEQMPLDAGHSWRRNIALSADDVLAAL
MMAR_4663|M.marinum_M ETGRQDVVELLRFCLEQGYQLRVIEQMPLDAGHQWRRNALLGSDDVLAAL
MUL_0281|M.ulcerans_Agy99 ETGRQDVVELLRFCLEQGYQLRVIEQMPLDAGHQWRRNALLGSDDVLAAL
TH_1071|M.thermoresistible__bu ETGLDDAVQLLRFCLDRGYQLRIIEQMPLDAGHQWRRDQTLSADEVLAAL
Mflv_1705|M.gilvum_PYR-GCK VTGLQDAVALLGFCLENGYQLRIIEQMPLDAGHSWQRDRALSADDILDTL
Mvan_5047|M.vanbaalenii_PYR-1 VSGLDDVVSLLRFCLEHGYQLRVIEQMPLDAGHSWERERALSADVILSAL
MSMEG_5698|M.smegmatis_MC2_155 VSGLDDAVELLRYCLQHGYQLRIIEQMPLDASHSWQRDNVIDADRILQTL
MAB_0871c|M.abscessus_ATCC_199 EQYKEDAVALLHFSLEHGYELRIIEQMPLDAGHSWSRARMVTADEIHAAL
MAV_4478|M.avium_104 HN-VGQLDEFAALASRYGATLRITRLRPSGRGADVWDELHPTADQQVQLY
: : . * **: . * . . . :*
Mb0893c|M.bovis_AF2122/97 RPHFRLRP---------DPAPRGSAPAELWLVDAGPNTPRGRFG------
Rv0869c|M.tuberculosis_H37Rv RPHFRLRP---------DPAPRGSAPAELWLVDAGPNTPRGRFG------
MMAR_4663|M.marinum_M QPHFRLRP---------DPAPRGSAPAELWLVDAGPDTPAGKFG------
MUL_0281|M.ulcerans_Agy99 QPHFRLRP---------DPAPRGSAPAELWLVDAGPDTPAGKFG------
TH_1071|M.thermoresistible__bu QREFRLSP---------DPTPRGSAPAQLWRIDG----TGATVG------
Mflv_1705|M.gilvum_PYR-GCK RRHFTLTP---------DPAPRGSAPAQLWRVHDG-TGVVGRVG------
Mvan_5047|M.vanbaalenii_PYR-1 RRHFTLTP---------DPRPRGSAPAQLWQVHDD-GHVTGHIG------
MSMEG_5698|M.smegmatis_MC2_155 QQHFELTP---------DSRPRGSAPAELWQVAEGPTHAAGTVG------
MAB_0871c|M.abscessus_ATCC_199 SREFSLSE---------DPAPRGSAPAQRWLVNGG----PATVG------
MAV_4478|M.avium_104 DWLVAKGERVLTGDSFFHLAPLGQSGALAGLNMCGAGRVVCLIDPVGDVY
. . * *.: * ..
Mb0893c|M.bovis_AF2122/97 ---------------------------------VIASVSHAFCSTCDRTR
Rv0869c|M.tuberculosis_H37Rv ---------------------------------VIASVSHAFCSTCDRTR
MMAR_4663|M.marinum_M ---------------------------------VIASVSHAFCSTCDRTR
MUL_0281|M.ulcerans_Agy99 ---------------------------------VIASVSHAFCSTCDRTR
TH_1071|M.thermoresistible__bu ---------------------------------IIATVSHAFCSACDRTR
Mflv_1705|M.gilvum_PYR-GCK ---------------------------------IIASVSHAFCSTCDRSR
Mvan_5047|M.vanbaalenii_PYR-1 ---------------------------------IIASVSDAFCSTCDRSR
MSMEG_5698|M.smegmatis_MC2_155 ---------------------------------VIASVSHAFCSACDRTR
MAB_0871c|M.abscessus_ATCC_199 ---------------------------------IIASVSRPFCGDCDRTR
MAV_4478|M.avium_104 ACPFAIHDRFLAGNVLSDGGFDNVWKNAPLFRELREPQSAGACGSCGHYD
: . * *. *.:
Mb0893c|M.bovis_AF2122/97 LTADGQIRSCLFS---TEETDLRRLLRGGADDDAIEAAWRAAMWSKPAGH
Rv0869c|M.tuberculosis_H37Rv LTADGQIRSCLFS---TEETDLRRLLRGGADDDAIEAAWRAAMWSKPAGH
MMAR_4663|M.marinum_M LTADGQVRSCLFS---TEETDLRGLLRAGAGDEAIEAAWRSAMWAKPAGH
MUL_0281|M.ulcerans_Agy99 LTADGQVRSCLFS---TEETDLRGLLRAGAGDEAIEAAWRGAMWAKPAGH
TH_1071|M.thermoresistible__bu LTADGQVRNCLFA---QQETDLRGLLRSGADDDAVEAAWRAAMWAKAAGH
Mflv_1705|M.gilvum_PYR-GCK LTADGQVRNCLFA---RDETDLRALLRSGADDDVLEAAWRAAMWAKAAGH
Mvan_5047|M.vanbaalenii_PYR-1 LTADGQVRNCLFA---RDETDLRALLRSGADDAALEDAWRAAMWAKAAGH
MSMEG_5698|M.smegmatis_MC2_155 LTADGQIRSCLFS---REETDLRHLLRGGADDAEIEAAWRAAMWSKPAGH
MAB_0871c|M.abscessus_ATCC_199 LTADGQVRNCLFA---TTETDLRGLLRSGASDAEVASAWQAAMWGKKPGH
MAV_4478|M.avium_104 SCRGGCMAAKFFTGLPLDGPDPECVQGHSAAALAGDREAPRPRADHSRGK
.* : :*: .* . : .* . : *:
Mb0893c|M.bovis_AF2122/97 GINA---------PDFIQPDRPMSAIGG----
Rv0869c|M.tuberculosis_H37Rv GINA---------PDFIQPDRPMSAIGG----
MMAR_4663|M.marinum_M GINN---------PDFVQPQRPMSAIGG----
MUL_0281|M.ulcerans_Agy99 GINN---------PDFLQPQRPMSAIGG----
TH_1071|M.thermoresistible__bu GIND---------PDFVQPARPMSAIGG----
Mflv_1705|M.gilvum_PYR-GCK GIND---------PDFVQPDRPMSAIGG----
Mvan_5047|M.vanbaalenii_PYR-1 GIND---------PGFVQPDRPMSAIGG----
MSMEG_5698|M.smegmatis_MC2_155 GIND---------PDFVQPVRPMSAIGG----
MAB_0871c|M.abscessus_ATCC_199 GIND---------PSFLQPDRPMSAIGG----
MAV_4478|M.avium_104 RIRQPVPLTLSVRPPVLTPAAPPARLCNESPV
*. * .: * * : : .