For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLVRIRKPSISQAGEMT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2995 | - | - | 100% (56) | hypothetical protein Mb2995 |
| M. bovis AF2122 / 97 | Mb2996 | - | 3e-08 | 65.62% (32) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4205 | - | 8e-08 | 65.71% (35) | 2,5-didehydrogluconate reductase |
| M. tuberculosis H37Rv | Rv2970A | - | 5e-28 | 100.00% (56) | hypothetical protein Rv2970A |
| M. leprae Br4923 | MLBr_01669 | - | 6e-07 | 59.38% (32) | putative oxidoreductase of Aldo/keto reductase family |
| M. abscessus ATCC 19977 | MAB_1528c | - | 1e-10 | 65.79% (38) | oxidoreductase |
| M. marinum M | MMAR_1744 | - | 6e-05 | 56.25% (32) | oxidoreductase |
| M. avium 104 | MAV_1085 | - | 2e-08 | 65.62% (32) | morphine 6-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2408 | - | 1e-12 | 88.57% (35) | 2,5-diketo-D-gluconic acid reductase A |
| M. thermoresistible (build 8) | TH_1525 | - | 9e-08 | 43.64% (55) | 2,5-diketo-D-gluconic acid reductase A |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2161 | - | 2e-07 | 65.62% (32) | 2,5-didehydrogluconate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1085|M.avium_104 ------MSKVPTIELNDGARIPQLGFGVYQIKPDETAAAVRAALDIGYRH
TH_1525|M.thermoresistible__bu ----VNMTTVPAITLNNGAQIPQVGFGVYQIPPDQTAAAVRTALDAGYRH
Mflv_4205|M.gilvum_PYR-GCK ---MTSAAAIPTVTLNDDNTMPVIGLGVGELSDAETEQAVTAALEAGYRL
Mvan_2161|M.vanbaalenii_PYR-1 ---MTSAAAIPTVILNDDNTMPVIGLGVGELSDAEAEQSVLAALEAGYRL
MLBr_01669|M.leprae_Br4923 MMPSTPRTSIPSITLNDENTMPLLGLGVAELSEDETERAVLAALEIGCRL
MMAR_1744|M.marinum_M -MPGAPSPSAPSIALNDENTMPVLGMGVAGLSDDETERAVSAALEIGCRL
MAB_1528c|M.abscessus_ATCC_199 ------------MTLNSGTTIPQLGYGVWQVPDDQARAAVSAALQVGYRS
MSMEG_2408|M.smegmatis_MC2_155 --------MSPRITLNDGNSIPQVGLGVWQTPAEDTERAVAAALQAGYRH
Mb2995|M.bovis_AF2122/97 --------------------------------------------------
Rv2970A|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1085|M.avium_104 IDTAEMYGNEREVAQGIRDAGLDRSEVFVTSKLNNGFHEPDAARRAFDAT
TH_1525|M.thermoresistible__bu IDTAQMYGNERGVAEGIRDAGLDRGEVFITSKLNNPYHRPDDARRAFDRT
Mflv_4205|M.gilvum_PYR-GCK IDTAAAYGNEAAVGRAIAASGVPRDELFVTTKLATEDAGFQSSQDALRAS
Mvan_2161|M.vanbaalenii_PYR-1 IDTAAAYGNEAAVGRAIAKSGVPRGELFVTTKLATDDLGFQSSQDALRAS
MLBr_01669|M.leprae_Br4923 IDTAAAYGNEAAVSRAIAASGIPRAQLFVTTKLATPDQGFTKSQDACNAS
MMAR_1744|M.marinum_M IDTAAAYGNEAAVGRAIAASGIPRAELFVTTKVATADHGFTASREACKAS
MAB_1528c|M.abscessus_ATCC_199 IDTAKIYDNEAGTGAAIAESGIPRGDVFLTTKLWNSDQGYDNALRAFDAS
MSMEG_2408|M.smegmatis_MC2_155 IDTAAAYRNETETGRAIANSGVPREDIFLVTKLWNSDQGYDATLAAFDAS
Mb2995|M.bovis_AF2122/97 --------------------------------------------------
Rv2970A|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1085|M.avium_104 LKALGSDYVDLFLIHWPLPTLYGGDFVSTWRVLEEFARDGRARSIGVSNF
TH_1525|M.thermoresistible__bu LTELGSDYVDLFLIHWPLPMHYDGDFVSTWKTLEEFAADGRARSIGVSNF
Mflv_4205|M.gilvum_PYR-GCK LERLGLDYVDLYLIHWPVSQQ--GKHVDSWGGLMKSKEVGLTRSIGVANF
Mvan_2161|M.vanbaalenii_PYR-1 LERLGLDYVDLYLIHWPAGSQ--GTYVDSWGGLMKLKELGLTRSIGVSNF
MLBr_01669|M.leprae_Br4923 LDRLGMDYVDLYLIHWPAPPV--GQYVDAWGGMIQSRGEGHARSIGVCNF
MMAR_1744|M.marinum_M LDRLGLDYVDLYLIHWPAPAA--GKYVDAFGGLIQARGEGFTRSIGVSNF
MAB_1528c|M.abscessus_ATCC_199 LERLGTDYVDLYLIHWPVPEL--DEYVASFKALQRIQADGRAKAIGVSNF
MSMEG_2408|M.smegmatis_MC2_155 VQRLGVDYLDLYLIHWPVPEN--NKFVDTFKAFAHLRDQGRIRSIGVSNF
Mb2995|M.bovis_AF2122/97 --------------------------------------------------
Rv2970A|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1085|M.avium_104 QVPHLERLATETDTVPAVNQVEVHPYFTNEKVRGYAREHGIAIEAWSPIA
TH_1525|M.thermoresistible__bu EPAHLDLLAAETSTVPAVNQVEIHPYFGNNDVRRYCAEHGIAVEAWAPIA
Mflv_4205|M.gilvum_PYR-GCK HGHHLDDIISLSFFTPAVNQIELHPLLNQAELRAVNAEHGIATEAYGPLG
Mvan_2161|M.vanbaalenii_PYR-1 HAQHLDDIIGLSFFTPAVNQIELHPLLNQAELRAVNAEHGIVTEAYSPLG
MLBr_01669|M.leprae_Br4923 TEEHLSAIIDLTFVTPAVNQIELHPLLNQDEMRKSNAQHNVITQSYTPLV
MMAR_1744|M.marinum_M TEEHVSNVIDLTFVTPAVNQVELHPLLNQDELRKANAQHNVVTQSYTPLA
MAB_1528c|M.abscessus_ATCC_199 TVDNLKRLIDETGEVPALNQIELHPRFTQPELRAFHAEYGIATEAWSPLG
MSMEG_2408|M.smegmatis_MC2_155 EPEHLTTLIEETGIVPAVNQIELHPLLPQQELRDVHAKLGIATEAWSPLG
Mb2995|M.bovis_AF2122/97 --------------------------------------------------
Rv2970A|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1085|M.avium_104 QGDVLGDAVINRIADGLGRTAAPVVLRWHIQRGDIVFPKTVNPDRMKSNF
TH_1525|M.thermoresistible__bu KGRVADDPVIAGIADRLGRTPAQVTLRWHIQRGDIVLPKSVTPERVRSNI
Mflv_4205|M.gilvum_PYR-GCK VGNLLSHSAVNAIAEAHGRTPAQVLIRWSLQLGNIVIPRSSSPERIRSNI
Mvan_2161|M.vanbaalenii_PYR-1 VGSLLSNPAVTAIADAQDRTPAQVLIRWSLQLGNVVISRSSSPERIKSNL
MLBr_01669|M.leprae_Br4923 LGRLMDNSTLTAIAAEYGKTPAQVLLRWNLQLGNAVVFRSAKAEHIASNF
MMAR_1744|M.marinum_M LGQLADNPTVTSIAGEYGKTPTQVLLRWNLQLGNAVIFGSSNAEHIATNL
MAB_1528c|M.abscessus_ATCC_199 QGTILEDATIGAIAQAHDVSAAQVILRWHLQLGNVVIPKSVTPARIAANF
MSMEG_2408|M.smegmatis_MC2_155 QGSLLADPVITGIAEQHGKTPAQVLIRWHIQLGNIVIPKSVNPERIASNF
Mb2995|M.bovis_AF2122/97 -----------------------MLIRWHIQLGNIVIPKSVNPMRIASNF
Rv2970A|M.tuberculosis_H37Rv -----------------------MLIRWHIQLGNIVIPKSVNPMRIASNF
: :** :* *: *. : .. :: :*:
MAV_1085|M.avium_104 ELFDFELDERAMEAISALDRGESGRRGPNPDTFDYIPR
TH_1525|M.thermoresistible__bu ALFDFELSDADMAAISALDKGEAGRMGPHPDKFDMI--
Mflv_4205|M.gilvum_PYR-GCK DVFGFELSEEQMSTLNGLDDG--TRFRPDPETYSGS--
Mvan_2161|M.vanbaalenii_PYR-1 DVFDFELTADQMAALDGLDEG--TRFRPDPETYTGS--
MLBr_01669|M.leprae_Br4923 DVFDFELAVNHMDAMNELHDG--TRLRPDPETYAGS--
MMAR_1744|M.marinum_M DVFEFELASQHMDAINGLNDG--TRLREDPMTFAGV--
MAB_1528c|M.abscessus_ATCC_199 DVFGFELSTDEVERITALDASD-GRIGPDPTTFNLH--
MSMEG_2408|M.smegmatis_MC2_155 DVFDFELSGQDITSIASLETG--KRLGPDPRTFNFTG-
Mb2995|M.bovis_AF2122/97 DAFDFPRSMTEPGLVRIRKPS----ISQAGEMT-----
Rv2970A|M.tuberculosis_H37Rv DAFDFPRSMTEPGLVRIRKPS----ISQAGEMT-----
* * : . .