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MRPGFVGLGFGQWPVYVVRWPKLHLTPRQRKRVLHRRRLLTDRPISLSQIPIRTGGPMNDPWPRPTQGPA KTIETDYLVIGAGAMGMAFTDTLITESGARVVMIDRACQPGGHWTTAYPFVRLHQPSAYYGVNSRALGNN TIDLVGWNQGLNELAPVGEICAYFDAVLQQQLLPTGRVDYFPMSEYLGDGRFRTLAGTEYVVTVNRRIVD ATYLRAVVPSMRPAPYSVAPGVDCVAPNELPKLGTRDRYVVVGAGKTGMDVCLWLLRNDVCPDKLTWIMP RDSWLIDRATLQPGPTFVRQFRESYGATLEAIGAATSTDDLFDRLETAGTLLRIDPSVRPSMYRCATVSH LELEQLRRIRDIVRMGHVQRIEPTTIVLDGGSVPATPTALYIDCTADGAPQRPAKPVFDADHLTLQAVRG CQQVFSAAFIAHVEFAYEDDAVKNELCTPIPHPDCDLDWMRLMHSDLGNFQRWLNDPDLTDWLSSARLNL LADLLPPLSHKPRVRERVVSMFQKRLGTAGDQLAKLLDAATATTEQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2023 | - | - | 100% (537) | hypothetical protein Mb2023 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2222 | - | 1e-147 | 55.27% (465) | hypothetical protein Mflv_2222 |
| M. tuberculosis H37Rv | Rv2000 | - | 0.0 | 100.00% (537) | hypothetical protein Rv2000 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2976 | - | 0.0 | 82.00% (461) | hypothetical protein MMAR_2976 |
| M. avium 104 | MAV_4416 | - | 1e-171 | 62.82% (468) | hypothetical protein MAV_4416 |
| M. smegmatis MC2 155 | MSMEG_5251 | - | 7e-07 | 26.70% (221) | hypothetical protein MSMEG_5251 |
| M. thermoresistible (build 8) | TH_3566 | - | 6e-05 | 39.74% (78) | PUTATIVE cyclohexanone monooxygenase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2023|M.bovis_AF2122/97 --------------------------------------------------
Rv2000|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2976|M.marinum_M --------------------------------------------------
MAV_4416|M.avium_104 --------------------------------------------------
Mflv_2222|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5251|M.smegmatis_MC2_155 --------------------------------------------------
TH_3566|M.thermoresistible__bu MPTDPTVLSAETASHAEELRMYLRHADAGVLVAVLAQLTGDPGVVDRFGP
Mb2023|M.bovis_AF2122/97 ---------------MRPGFVGLGFGQWPVYVVRWPKLHLTPRQRKRVLH
Rv2000|M.tuberculosis_H37Rv ---------------MRPGFVGLGFGQWPVYVVRWPKLHLTPRQRKRVLH
MMAR_2976|M.marinum_M --------------------------------------------------
MAV_4416|M.avium_104 --------------------------------------------------
Mflv_2222|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5251|M.smegmatis_MC2_155 --------------------------------------------------
TH_3566|M.thermoresistible__bu RIEHVPDPPEHVGVTDAATLDALVEAVVAAMGGDRPDHRLPPDDPQLFVR
Mb2023|M.bovis_AF2122/97 RRRLLTDRPISLSQI-PIRTGGPMNDPWPRPTQGPAKTIETDYLVIGAGA
Rv2000|M.tuberculosis_H37Rv RRRLLTDRPISLSQI-PIRTGGPMNDPWPRPTQGPAKTIETDYLVIGAGA
MMAR_2976|M.marinum_M -----------------MREG--------EHVQAPAKAIEADYLVVGAGA
MAV_4416|M.avium_104 -----------------------------------MHTIEADYLVVGAGA
Mflv_2222|M.gilvum_PYR-GCK -----------------------------------MTGIEADYLVVGAGA
MSMEG_5251|M.smegmatis_MC2_155 -------------------------MSTSAETQDNQRVDTCDLCVVGAGI
TH_3566|M.thermoresistible__bu IAPLALGTPVDTDYVGLLLEQGGFHPSQPVLPRTARLPADFSVTVIGAGM
. *:***
Mb2023|M.bovis_AF2122/97 MGMAFTDTLITESG---ARVVMIDRACQPGGHWT-TAYPFVRLHQPSAYY
Rv2000|M.tuberculosis_H37Rv MGMAFTDTLITESG---ARVVMIDRACQPGGHWT-TAYPFVRLHQPSAYY
MMAR_2976|M.marinum_M MGMAFTDTLITESD---ARVVIVDRAHAPGGHWT-TAYPFVRLHQPSAYY
MAV_4416|M.avium_104 MGMAFIDTLVTETAASQARVVVVDRHHAPGGHWT-IAYPFVRLHQPSAFY
Mflv_2222|M.gilvum_PYR-GCK MGMAFVDTLLAETRDAGTTVVLVDENHQPGGHWN-TVYPFVRLHQPSAYY
MSMEG_5251|M.smegmatis_MC2_155 AGLNALFVASRYLR-RDQKIVLLDRRDRVGGMWV-DTYEYVRLHQPHPMF
TH_3566|M.thermoresistible__bu AGMAAALELADAGI----DYQIIDRNDDVGGTWCTTVYPGIGVDTPSAYY
*: ::*. ** * .* : :. * . :
Mb2023|M.bovis_AF2122/97 GVN--SRALGNN---TIDLVGWNQGLNELAPVGEICAYFDAVLQQQLLPT
Rv2000|M.tuberculosis_H37Rv GVN--SRALGNN---TIDLVGWNQGLNELAPVGEICAYFDAVLQQQLLPT
MMAR_2976|M.marinum_M GVN--SRPLGNN---TIDAVGWNQGLNELAPVGEICAYFDAVMQQQFLPT
MAV_4416|M.avium_104 GVN--SLRLGGD---SIDQIGWNRGLYELATADEICAYYDRVMRTRLLPT
Mflv_2222|M.gilvum_PYR-GCK GVN--SEPLGDEE--AIDRSGFNEGFFELASGHEVCAYYDHVMRNHLLPT
MSMEG_5251|M.smegmatis_MC2_155 TAGNIEWTLGREPSYLPTKTEVLDHFRHCLDVIRKQVTVDARFGWEFLSD
TH_3566|M.thermoresistible__bu SLS---RDINPD-----WSSYYPNGAEYQQYLLSVADKHGLREHIRFGTE
. :. : . .: .
Mb2023|M.bovis_AF2122/97 GRVDYFPMSEYLGDGRFRTLAGTEYVVTVNRRIVDATYLRAVVPSMRPAP
Rv2000|M.tuberculosis_H37Rv GRVDYFPMSEYLGDGRFRTLAGTEYVVTVNRRIVDATYLRAVVPSMRPAP
MMAR_2976|M.marinum_M GRVEYFPMSEYLGDGRFRTLGGAEHQVTVSRRIVDATYLRAVVPSMRPTP
MAV_4416|M.avium_104 GRVRYFPDSEYRGDGRFRTSAGADHTVEVTRRIVDATYMHVSVPAMRPPP
Mflv_2222|M.gilvum_PYR-GCK GRLTYLPMTRYLGDNRIRTLDGAEQTVTVRRRTVDATYLLTVVQSMRSAP
MSMEG_5251|M.smegmatis_MC2_155 KEFGSGPGAGVR--ITCRVPDGTERIIKAPRLIKAYGVRFRPNAPMKLSS
TH_3566|M.thermoresistible__bu VTALRWDDDRDQWQVHTVGPDGTKQVSYANVVIPAAGYLNRPRWPEVEGR
*:. . .
Mb2023|M.bovis_AF2122/97 YSVAPGVDCVAPNELPKLG-TRDRYVVVGAGKTGMDVCLWLLRNDVC---
Rv2000|M.tuberculosis_H37Rv YSVAPGVDCVAPNELPKLG-TRDRYVVVGAGKTGMDVCLWLLRNDVC---
MMAR_2976|M.marinum_M YPVAPGIDCIAPNDLPKFT-GKDRYVIVGAGKTAMDVCLWLLRNSVD---
MAV_4416|M.avium_104 YTVGDGVDCVPPNELPRRP-GYQRYVVVGAGKTGIDTCLWLLGQGVE---
Mflv_2222|M.gilvum_PYR-GCK FSVADGVEVVAPNDLPRRAPHHDHYTVVGGGKTGMDCCLWLLRNGVP---
MSMEG_5251|M.smegmatis_MC2_155 TRVRSVSPDTCDVRRGDIRDSDAPVWIIGGGKTGMDTAHTLITAQTGREV
TH_3566|M.thermoresistible__bu HTFTG-VSVHSAQWDPELDLTGKRVAVIGAGCTAVQIVDACVDQVAHLT-
. ::*.* *.:: : .
Mb2023|M.bovis_AF2122/97 ---PDKLTWIMPRD----------SWLIDRATLQPGPTFVRQFRESYGAT
Rv2000|M.tuberculosis_H37Rv ---PDKLTWIMPRD----------SWLIDRATLQPGPTFVRQFRESYGAT
MMAR_2976|M.marinum_M ---PGQLSWIKPRD----------AWLIDRATLQPGPTFIKQFRDSYGIT
MAV_4416|M.avium_104 ---PDRLTWIMPRD----------SWLLDRATMQPGALFAEQIKHSFTAQ
Mflv_2222|M.gilvum_PYR-GCK ---ADAVRWVRPRD----------SWLLNRAHIQPGEQFAPQLRDAMAAR
MSMEG_5251|M.smegmatis_MC2_155 NLVAGSGTYFSCRD----------KLFPTGIRRWGGGRSINAMAEEMCSR
TH_3566|M.thermoresistible__bu -VFQRQPHWVAPRKRLSDDVPEHRRWLNNHIPFYANWNRLKSFWGTADNN
:. *. : . :
Mb2023|M.bovis_AF2122/97 LEAIGAAT--STDDLFDRL-----ETAGTLLRIDPSVRPSMYRCATVSHL
Rv2000|M.tuberculosis_H37Rv LEAIGAAT--STDDLFDRL-----ETAGTLLRIDPSVRPSMYRCATVSHL
MMAR_2976|M.marinum_M LEAIGRAT--SIRDLFDRL-----EKAGTLLRLDPAVRPTMYRCATVSQP
MAV_4416|M.avium_104 LRAINEAG--SVAELFSRL-----EAAGLLLRIDPAVRPTMYRCATVTRL
Mflv_2222|M.gilvum_PYR-GCK MQAISEAA--SVEHLFTLL-----EDAEVLLRLDPSVWPTMYHCAIVSQR
MSMEG_5251|M.smegmatis_MC2_155 FDGTNEGE--VADWFRREFGVWLTPQTGNFLFGVLSEAENATIAAGLREV
TH_3566|M.thermoresistible__bu YPVILRDPQWAAEHPLSISKANDALLQLCLDYIDRTFGAGSELAAKVTPD
: : .* :
Mb2023|M.bovis_AF2122/97 ELEQLRRIRD-------IVRMGHVQRIEPTTIVLDGG------------S
Rv2000|M.tuberculosis_H37Rv ELEQLRRIRD-------IVRMGHVQRIEPTTIVLDGG------------S
MMAR_2976|M.marinum_M EFDQLRRIED-------VVRMGHVQRIDSTEIVLDGG------------S
MAV_4416|M.avium_104 ELEQLRRITD-------VVRLGHVRSIEPGAMVLDGG------------A
Mflv_2222|M.gilvum_PYR-GCK ELEYLRRIED-------VVRLGHIEHAEPDRVRLTGA------------T
MSMEG_5251|M.smegmatis_MC2_155 LMDHLVDVVDRDGSTEMVLRSGARRQVEDDSWIVNCT------------G
TH_3566|M.thermoresistible__bu FAPYGKRIIRDPGGYYAALTRPHVNLEAAEPARINERGIVTQEGRQIDLD
: : . :
Mb2023|M.bovis_AF2122/97 VPATPTALYIDCTADGAPQRPAKPVFDADHLTLQAVR--GCQQVFSAAFI
Rv2000|M.tuberculosis_H37Rv VPATPTALYIDCTADGAPQRPAKPVFDADHLTLQAVR--GCQQVFSAAFI
MMAR_2976|M.marinum_M VPCSASALYVDCTADGAPQRPAKPVFDGDHLTLQAVR--GCQQVFSAAFT
MAV_4416|M.avium_104 VAVDGRALYLDCTADGAEKRPATPIFTPGRITLQSVR--GCQQIFSAALI
Mflv_2222|M.gilvum_PYR-GCK IPATP-SLYVDCTTQGLPRPPSVPVFDGDRITLQSVR--SCQQVFSSAFI
MSMEG_5251|M.smegmatis_MC2_155 YLLEGDHSYEPYLSAGGSVLSIQPRSAALHLTSYSAY--FLTHLFLMDKL
TH_3566|M.thermoresistible__bu VIIYATGYYLDFLSTVDIRGRDGVRLAEVWGDSPSAYRGGTVPGFPNMFV
* : :. *
Mb2023|M.bovis_AF2122/97 AHV---EFAYEDDAVKNELCTPIPHPDCDLDWMRLMHSDLGNFQRWLNDP
Rv2000|M.tuberculosis_H37Rv AHV---EFAYEDDAVKNELCTPIPHPDCDLDWMRLMHSDLGNFQRWLNDP
MMAR_2976|M.marinum_M AHV---ELAYDGDEVKNELCTPIPHPDSDLDWMRLTHSDLRNFQRWLDDV
MAV_4416|M.avium_104 AHV---EAGYGDDARRNELCVPLPHPDTDVDWLRLALADYTNQLRWFDDP
Mflv_2222|M.gilvum_PYR-GCK AHA---ETTFSDDDTRNALCVPVVHPDAPIDWLRHMSEDNAASMRWIRDP
MSMEG_5251|M.smegmatis_MC2_155 GDLPLYEADLVELWQKHRAVAPYALFTLVQYNLGLIADTVPGKVFRECGL
TH_3566|M.thermoresistible__bu SSAP--NYSPGHGAGHNFGVEIMVHYVMECLQLMALRGARTIEVKPEAFT
. : :: :
Mb2023|M.bovis_AF2122/97 DLTDWLSSARLN----LLADLLPPLS-HKPRVRERVVSMFQKRLGTAGDQ
Rv2000|M.tuberculosis_H37Rv DLTDWLSSARLN----LLADLLPPLS-HKPRVRERVVSMFQKRLGTAGDQ
MMAR_2976|M.marinum_M ELTDWLSSARLN----LLADLLPPLS-HKPRVRDRVVSMFRSKLNIASEQ
MAV_4416|M.avium_104 ELMTWLSGARLDLFGHLIGHLLPSAS-AKPRVRARILGIAKSVFAATAAR
Mflv_2222|M.gilvum_PYR-GCK ELMTWLRTARLN----AARDLFPVFPPGKERVRDKAMGALAVALRKTNEE
MSMEG_5251|M.smegmatis_MC2_155 DFARWYPWYRRT----AAGLHFMRTHRRQSEHLRRSLDTVRERFGVRCGP
TH_3566|M.thermoresistible__bu DYVRRVDEAMAD----TVWCHTPTAHTYYRSGSGRIVTAFPFRLIDMWQS
: : : :
Mb2023|M.bovis_AF2122/97 LAKLLDAA--TATTEQR
Rv2000|M.tuberculosis_H37Rv LAKLLDAA--TATTEQR
MMAR_2976|M.marinum_M LEKLLSDHGHDGASQQQ
MAV_4416|M.avium_104 LGELLAAEAALAAS---
Mflv_2222|M.gilvum_PYR-GCK LAALMAGAS--------
MSMEG_5251|M.smegmatis_MC2_155 LIEGEARASAVAAG---
TH_3566|M.thermoresistible__bu HRAPIEDDFILR-----