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MREGEHVQAPAKAIEADYLVVGAGAMGMAFTDTLITESDARVVIVDRAHAPGGHWTTAYPFVRLHQPSAY YGVNSRPLGNNTIDAVGWNQGLNELAPVGEICAYFDAVMQQQFLPTGRVEYFPMSEYLGDGRFRTLGGAE HQVTVSRRIVDATYLRAVVPSMRPTPYPVAPGIDCIAPNDLPKFTGKDRYVIVGAGKTAMDVCLWLLRNS VDPGQLSWIKPRDAWLIDRATLQPGPTFIKQFRDSYGITLEAIGRATSIRDLFDRLEKAGTLLRLDPAVR PTMYRCATVSQPEFDQLRRIEDVVRMGHVQRIDSTEIVLDGGSVPCSASALYVDCTADGAPQRPAKPVFD GDHLTLQAVRGCQQVFSAAFTAHVELAYDGDEVKNELCTPIPHPDSDLDWMRLTHSDLRNFQRWLDDVEL TDWLSSARLNLLADLLPPLSHKPRVRDRVVSMFRSKLNIASEQLEKLLSDHGHDGASQQQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2976 | - | - | 100% (480) | hypothetical protein MMAR_2976 |
| M. marinum M | MMAR_3139 | - | 3e-05 | 26.15% (218) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2023 | - | 0.0 | 82.00% (461) | hypothetical protein Mb2023 |
| M. gilvum PYR-GCK | Mflv_2222 | - | 1e-143 | 54.33% (462) | hypothetical protein Mflv_2222 |
| M. tuberculosis H37Rv | Rv2000 | - | 0.0 | 82.00% (461) | hypothetical protein Rv2000 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | MAV_4416 | - | 1e-168 | 61.34% (463) | hypothetical protein MAV_4416 |
| M. smegmatis MC2 155 | MSMEG_5251 | - | 2e-06 | 27.01% (211) | hypothetical protein MSMEG_5251 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2023|M.bovis_AF2122/97 MRPGFVGLGFGQWPVYVVRWPKLHLTPRQRKRVLHRRRLLTDRPISLSQI
Rv2000|M.tuberculosis_H37Rv MRPGFVGLGFGQWPVYVVRWPKLHLTPRQRKRVLHRRRLLTDRPISLSQI
MMAR_2976|M.marinum_M --------------------------------------------------
MAV_4416|M.avium_104 --------------------------------------------------
Mflv_2222|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5251|M.smegmatis_MC2_155 --------------------------------------------------
Mb2023|M.bovis_AF2122/97 PIRTGGPMNDPWPRPTQGPAKTIETDYLVIGAGAMGMAFTDTLITESG--
Rv2000|M.tuberculosis_H37Rv PIRTGGPMNDPWPRPTQGPAKTIETDYLVIGAGAMGMAFTDTLITESG--
MMAR_2976|M.marinum_M -MREG--------EHVQAPAKAIEADYLVVGAGAMGMAFTDTLITESD--
MAV_4416|M.avium_104 -------------------MHTIEADYLVVGAGAMGMAFIDTLVTETAAS
Mflv_2222|M.gilvum_PYR-GCK -------------------MTGIEADYLVVGAGAMGMAFVDTLLAETRDA
MSMEG_5251|M.smegmatis_MC2_155 ---------MSTSAETQDNQRVDTCDLCVVGAGIAGLNALFVASRYLR-R
* *:*** *: .
Mb2023|M.bovis_AF2122/97 -ARVVMIDRACQPGGHWTTAYPFVRLHQPSAYYGVN--SRALGNN---TI
Rv2000|M.tuberculosis_H37Rv -ARVVMIDRACQPGGHWTTAYPFVRLHQPSAYYGVN--SRALGNN---TI
MMAR_2976|M.marinum_M -ARVVIVDRAHAPGGHWTTAYPFVRLHQPSAYYGVN--SRPLGNN---TI
MAV_4416|M.avium_104 QARVVVVDRHHAPGGHWTIAYPFVRLHQPSAFYGVN--SLRLGGD---SI
Mflv_2222|M.gilvum_PYR-GCK GTTVVLVDENHQPGGHWNTVYPFVRLHQPSAYYGVN--SEPLGDEE--AI
MSMEG_5251|M.smegmatis_MC2_155 DQKIVLLDRRDRVGGMWVDTYEYVRLHQPHPMFTAGNIEWTLGREPSYLP
:*::*. ** * .* :****** . : .. . ** :
Mb2023|M.bovis_AF2122/97 DLVGWNQGLNELAPVGEICAYFDAVLQQQLLPTGRVDYFPMSEYLGDGRF
Rv2000|M.tuberculosis_H37Rv DLVGWNQGLNELAPVGEICAYFDAVLQQQLLPTGRVDYFPMSEYLGDGRF
MMAR_2976|M.marinum_M DAVGWNQGLNELAPVGEICAYFDAVMQQQFLPTGRVEYFPMSEYLGDGRF
MAV_4416|M.avium_104 DQIGWNRGLYELATADEICAYYDRVMRTRLLPTGRVRYFPDSEYRGDGRF
Mflv_2222|M.gilvum_PYR-GCK DRSGFNEGFFELASGHEVCAYYDHVMRNHLLPTGRLTYLPMTRYLGDNRI
MSMEG_5251|M.smegmatis_MC2_155 TKTEVLDHFRHCLDVIRKQVTVDARFGWEFLSDKEFGSGPGAGVR--ITC
: . . . * : .:*. .. * :
Mb2023|M.bovis_AF2122/97 RTLAGTEYVVTVNRRIVDATYLRAVVPSMRPAPYSVAPGVDCVAPNELPK
Rv2000|M.tuberculosis_H37Rv RTLAGTEYVVTVNRRIVDATYLRAVVPSMRPAPYSVAPGVDCVAPNELPK
MMAR_2976|M.marinum_M RTLGGAEHQVTVSRRIVDATYLRAVVPSMRPTPYPVAPGIDCIAPNDLPK
MAV_4416|M.avium_104 RTSAGADHTVEVTRRIVDATYMHVSVPAMRPPPYTVGDGVDCVPPNELPR
Mflv_2222|M.gilvum_PYR-GCK RTLDGAEQTVTVRRRTVDATYLLTVVQSMRSAPFSVADGVEVVAPNDLPR
MSMEG_5251|M.smegmatis_MC2_155 RVPDGTERIIKAPRLIKAYGVRFRPNAPMKLSSTRVRSVSPDTCDVRRGD
*. *:: : . * .*: .. *
Mb2023|M.bovis_AF2122/97 LG-TRDRYVVVGAGKTGMDVCLWLLRNDVC------PDKLTWIMPRDSWL
Rv2000|M.tuberculosis_H37Rv LG-TRDRYVVVGAGKTGMDVCLWLLRNDVC------PDKLTWIMPRDSWL
MMAR_2976|M.marinum_M FT-GKDRYVIVGAGKTAMDVCLWLLRNSVD------PGQLSWIKPRDAWL
MAV_4416|M.avium_104 RP-GYQRYVVVGAGKTGIDTCLWLLGQGVE------PDRLTWIMPRDSWL
Mflv_2222|M.gilvum_PYR-GCK RAPHHDHYTVVGGGKTGMDCCLWLLRNGVP------ADAVRWVRPRDSWL
MSMEG_5251|M.smegmatis_MC2_155 IRDSDAPVWIIGGGKTGMDTAHTLITAQTGREVNLVAGSGTYFSCRDKLF
::*.***.:* . *: . .. :. ** :
Mb2023|M.bovis_AF2122/97 IDRATLQPGPTFVRQFRESYGATLEAIGAATSTDDLFDRL-----ETAGT
Rv2000|M.tuberculosis_H37Rv IDRATLQPGPTFVRQFRESYGATLEAIGAATSTDDLFDRL-----ETAGT
MMAR_2976|M.marinum_M IDRATLQPGPTFIKQFRDSYGITLEAIGRATSIRDLFDRL-----EKAGT
MAV_4416|M.avium_104 LDRATMQPGALFAEQIKHSFTAQLRAINEAGSVAELFSRL-----EAAGL
Mflv_2222|M.gilvum_PYR-GCK LNRAHIQPGEQFAPQLRDAMAARMQAISEAASVEHLFTLL-----EDAEV
MSMEG_5251|M.smegmatis_MC2_155 PTGIRRWGGGRSINAMAEEMCSRFDGTNEGEVADWFRREFGVWLTPQTGN
* : . : . . . : : :
Mb2023|M.bovis_AF2122/97 LLRIDPSVRPSMYRCATVSHLELEQLRRIRD-------IVRMGHVQRIEP
Rv2000|M.tuberculosis_H37Rv LLRIDPSVRPSMYRCATVSHLELEQLRRIRD-------IVRMGHVQRIEP
MMAR_2976|M.marinum_M LLRLDPAVRPTMYRCATVSQPEFDQLRRIED-------VVRMGHVQRIDS
MAV_4416|M.avium_104 LLRIDPAVRPTMYRCATVTRLELEQLRRITD-------VVRLGHVRSIEP
Mflv_2222|M.gilvum_PYR-GCK LLRLDPSVWPTMYHCAIVSQRELEYLRRIED-------VVRLGHIEHAEP
MSMEG_5251|M.smegmatis_MC2_155 FLFGVLSEAENATIAAGLREVLMDHLVDVVDRDGSTEMVLRSGARRQVED
:* : . .* : . :: * : * ::* * . :
Mb2023|M.bovis_AF2122/97 TTIVLDGGSVPATPTALYIDCTADGAPQRPAKPVFDADHLTLQAVRGCQQ
Rv2000|M.tuberculosis_H37Rv TTIVLDGGSVPATPTALYIDCTADGAPQRPAKPVFDADHLTLQAVRGCQQ
MMAR_2976|M.marinum_M TEIVLDGGSVPCSASALYVDCTADGAPQRPAKPVFDGDHLTLQAVRGCQQ
MAV_4416|M.avium_104 GAMVLDGGAVAVDGRALYLDCTADGAEKRPATPIFTPGRITLQSVRGCQQ
Mflv_2222|M.gilvum_PYR-GCK DRVRLTGATIPATP-SLYVDCTTQGLPRPPSVPVFDGDRITLQSVRSCQQ
MSMEG_5251|M.smegmatis_MC2_155 DSWIVNCTGYLLEGDHSYEPYLSAGGSVLSIQPRSAALHLTSYSAYFLTH
: * : * . * ::* :. :
Mb2023|M.bovis_AF2122/97 VFSAAFIAHV---EFAYEDDAVKNELCTPIPHPDCDLDWMRLMHSDLGNF
Rv2000|M.tuberculosis_H37Rv VFSAAFIAHV---EFAYEDDAVKNELCTPIPHPDCDLDWMRLMHSDLGNF
MMAR_2976|M.marinum_M VFSAAFTAHV---ELAYDGDEVKNELCTPIPHPDSDLDWMRLTHSDLRNF
MAV_4416|M.avium_104 IFSAALIAHV---EAGYGDDARRNELCVPLPHPDTDVDWLRLALADYTNQ
Mflv_2222|M.gilvum_PYR-GCK VFSSAFIAHA---ETTFSDDDTRNALCVPVVHPDAPIDWLRHMSEDNAAS
MSMEG_5251|M.smegmatis_MC2_155 LFLMDKLGDLPLYEADLVELWQKHRAVAPYALFTLVQYNLGLIADTVPGK
:* .. * :: .* :
Mb2023|M.bovis_AF2122/97 QRWLNDPDLTDWLSSARLN----LLADLLPPLS-HKPRVRERVVSMFQKR
Rv2000|M.tuberculosis_H37Rv QRWLNDPDLTDWLSSARLN----LLADLLPPLS-HKPRVRERVVSMFQKR
MMAR_2976|M.marinum_M QRWLDDVELTDWLSSARLN----LLADLLPPLS-HKPRVRDRVVSMFRSK
MAV_4416|M.avium_104 LRWFDDPELMTWLSGARLDLFGHLIGHLLPSAS-AKPRVRARILGIAKSV
Mflv_2222|M.gilvum_PYR-GCK MRWIRDPELMTWLRTARLN----AARDLFPVFPPGKERVRDKAMGALAVA
MSMEG_5251|M.smegmatis_MC2_155 VFRECGLDFARWYPWYRRT----AAGLHFMRTHRRQSEHLRRSLDTVRER
. :: * * : : . : :.
Mb2023|M.bovis_AF2122/97 LGTAGDQLAKLLDAA--TATTEQR
Rv2000|M.tuberculosis_H37Rv LGTAGDQLAKLLDAA--TATTEQR
MMAR_2976|M.marinum_M LNIASEQLEKLLSDHGHDGASQQQ
MAV_4416|M.avium_104 FAATAARLGELLAAEAALAAS---
Mflv_2222|M.gilvum_PYR-GCK LRKTNEELAALMAGAS--------
MSMEG_5251|M.smegmatis_MC2_155 FGVRCGPLIEGEARASAVAAG---
: *