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MSRAAGLPRLSWFAGLTWFAGGSTGAGCAAHPALAGLTAGARCPAYAAISASTARPAATALPAVAASTAR PAATAGTTPATGASGSARPTDAAGMADLARPGVVATHAVRTLGTTGSRAIGLCPCQPLDCPRSPQATPNL GSMGRSLDGPQWRRARVRLCGRWWRRSNTTRGASPRPPSTCRGDNVSMIELEVHQADVTKLELDAITNAA NTRLRHAGGVAAAIARAGGPELQRESTEKAPIGLGEAVETTAGDMPARYVIHAATMELGGPTSGEIITAA TAATLRKADELGCRSLALVAFGTGVGGFPLDDAARLMVGAVRRHRPGSLQRVVFAVHGDAAERAFSAAIQ AGEDTARR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1934c | lppD | - | 100% (358) | lipoprotein LppD |
| M. bovis AF2122 / 97 | Mb3626c | PE_PGRS59 | 6e-05 | 29.89% (174) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3185 | - | 2e-19 | 39.23% (130) | appr-1-p processing domain-containing protein |
| M. tuberculosis H37Rv | Rv1899c | lppD | 0.0 | 95.53% (358) | lipoprotein LppD |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2794 | lppD | 8e-76 | 86.59% (164) | lipoprotein LppD |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2536 | - | 3e-19 | 42.62% (122) | PUTATIVE Appr-1-p processing domain protein |
| M. ulcerans Agy99 | MUL_2958 | lppD | 9e-76 | 85.98% (164) | lipoprotein LppD |
| M. vanbaalenii PYR-1 | Mvan_5241 | - | 9e-05 | 30.33% (122) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3185|M.gilvum_PYR-GCK --------------------------------------------------
TH_2536|M.thermoresistible__bu --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 MSRAAGLPRLSWFAGLTWFAGGSTGAGCAAHPALAGLTAGARCPAYAAIS
Rv1899c|M.tuberculosis_H37Rv MSRAAGLPRLSWFAGLTWFAGGSTGAGCAAHPALAGLTAGARCPAYAAIS
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK --------------------------------------------------
TH_2536|M.thermoresistible__bu --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 ASTARPAATALPAVAASTARPAATAGTTPATGASGSARPTDAAGMADLAR
Rv1899c|M.tuberculosis_H37Rv ASTAR---------------PAATAGTTPATGASGSARPTDAAGMADLAR
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 ----------------------MKFKPTVAAIITTAAAAAVGVVGAGSAS
Mflv_3185|M.gilvum_PYR-GCK --------------------------------------------------
TH_2536|M.thermoresistible__bu --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 PGVVATHAVRTLGTTGSRAIGLCPCQPLDCPRSPQATPNLGSMGRSLDGP
Rv1899c|M.tuberculosis_H37Rv PGVVATHAVRTLGTTGSRAIGLCPCQPLDCPRSPQATLNLGSMGRSLDGP
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 ADAEVQYLGQPGELVNGSVIQHWTVTGLKPSSDVIPYRPVGTLWEATATD
Mflv_3185|M.gilvum_PYR-GCK -----------------------------MPRCILGSVLTITAVRGDITE
TH_2536|M.thermoresistible__bu -----------------------------MP--------IITAVQGDITK
Mb1934c|M.bovis_AF2122/97 QWRRARVRLCGRWWRRSNTTRGASPRPPSTCRGDNVSMIELEVHQADVTK
Rv1899c|M.tuberculosis_H37Rv QWRRARVRLCGRWWRRSNTTRGASPRPPSTCRGDNVSMIELEVHQADVTK
MMAR_2794|M.marinum_M -------------------------------------MIELEVVQADVTK
MUL_2958|M.ulcerans_Agy99 -------------------------------------MIELEVVQADVTK
Mvan_5241|M.vanbaalenii_PYR-1 EAIAGTVTPIVSNLNARAENGDTYRVLFGVATEQGVNPSTLAQGQKTTGK
: : :
Mflv_3185|M.gilvum_PYR-GCK QEVDAVVNPANTAMRGGGGADGAIHRAGGPAILRDCVKRFPDGLATGDAG
TH_2536|M.thermoresistible__bu QTVDAIVNAANRAMRGGGGVDGAIHRAGGPAILRDCIERFPDGLATGDAG
Mb1934c|M.bovis_AF2122/97 LELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTEKAPIGLG--EAV
Rv1899c|M.tuberculosis_H37Rv LELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTEKAPIGLG--EAV
MMAR_2794|M.marinum_M LELDAITNAANTQLRHAGGVAAAISRAGGPDIQRESNEKAPIGLG--EAV
MUL_2958|M.ulcerans_Agy99 LELDAITNAANTQLRHAGGVAAAISRAGGPDIQRESNEKAPIGLG--EAV
Mvan_5241|M.vanbaalenii_PYR-1 IYFDVTGQQPDSVFYSDGGSEVLLWLEAPPAPATGSAGSGASGYGSEASP
.*. : .: : ** : . * . . * . :
Mflv_3185|M.gilvum_PYR-GCK WTTAGDLPAQWVIHTVGPNYDTGQRNRSLLESCYRRALKVADELGARIVA
TH_2536|M.thermoresistible__bu WTTAGDLAARWVIHTVGPNYRAGERDRSLLESCYRRSLEVADELGAATVA
Mb1934c|M.bovis_AF2122/97 ETTAGDMPARYVIHAATMELG-GPTSGEIITAATAATLRKADELGCRSLA
Rv1899c|M.tuberculosis_H37Rv ETTAGDMPARYVIHAATMELG-GPTSGEIITAATAATLRKADELGCRSLA
MMAR_2794|M.marinum_M ETTAGEMPARYVIHAATMELG-GPTSSEIISRATSSALRKADELGCRSLA
MUL_2958|M.ulcerans_Agy99 ETTAGEMPARYVIHAATMELG-GPTSSELISRATSSALRKADELGCRSLA
Mvan_5241|M.vanbaalenii_PYR-1 SAAADTATPETPGTTPAAETPTSVVPTPVAAPAGSSGTPLPEGSSGTPLP
::*. ... : : . : . .: . :.
Mflv_3185|M.gilvum_PYR-GCK FPLISTGSFG-WPRQDAIAAAIETIAAADTRVDEARLVAFDPKTHEEIRS
TH_2536|M.thermoresistible__bu FPLISSGIYG-WPRHDAIAAAIETIGLADARVEEARIVAFDLDTYEAVRT
Mb1934c|M.bovis_AF2122/97 LVAFGTGVGG-FPLDDAARLMVGAVRRHRPGSLQRVVFAVHGDAAERAFS
Rv1899c|M.tuberculosis_H37Rv LVAFGTGVGG-FPLDDAARLMVGAVRRHRPGSLQRVVFAVHGDAAERAFS
MMAR_2794|M.marinum_M LVAFGTGVGG-FPLERAARLMVEAVRRHHPGSLKRVVFAVHGNAAEKAFV
MUL_2958|M.ulcerans_Agy99 LVAFGTGVGG-FPLERAARLMVEAVRRHHPGSLKRVVFAVHGNAAEKAFV
Mvan_5241|M.vanbaalenii_PYR-1 EGSSGTPLPAGAAPVEAGPAPVPAGVAPAPHGSSGTPLPAGAPAVEGVQP
.: . . * : : . . .. : *
Mflv_3185|M.gilvum_PYR-GCK ALATWTPIRILQGVQVLHQRGYHRIRVWPGVSPSGMYWRVAINTAGHLTD
TH_2536|M.thermoresistible__bu QLEQRT--------------------------------------------
Mb1934c|M.bovis_AF2122/97 AAIQAGEDTARR--------------------------------------
Rv1899c|M.tuberculosis_H37Rv AAIQAGEDTARR--------------------------------------
MMAR_2794|M.marinum_M AAVQA---------------------------------------------
MUL_2958|M.ulcerans_Agy99 AAVQA---------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 APAPGAPTTTVVVPAPPA--------------------------------
Mflv_3185|M.gilvum_PYR-GCK EGYPEVGDYDTAVLYPTGSLNELAGNEVTVTTRPEMVADLILEQLPEAAP
TH_2536|M.thermoresistible__bu --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK TGDDPAYVSWFAELMRLVEQFQLPPIAYAEYFDASAGWEIGWGSGNRHPC
TH_2536|M.thermoresistible__bu --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK PPKPAITTRRRSAPMPSLPSTSMSDNTANALYRLETILQKATGLSPKVSA
TH_2536|M.thermoresistible__bu --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK VEGTLIPRGDPLLPGVTIKFAATHARGADRAALFFDDKNVHLGVWPAELQ
TH_2536|M.thermoresistible__bu --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK PQYTYVYSDPARVEALLDLDTHGDFTVEPNFQLAHRFAQPLQRWFPTRLL
TH_2536|M.thermoresistible__bu --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK SAEDYLQQWVDDFHDGRAGGRTRDELADPGFFQWLAERRYASAAEEESLH
TH_2536|M.thermoresistible__bu --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK HWLDSKKAGIQFHVRPGVQILRTWLYEEAFAIEGQNEFAVQVRNATNQIL
TH_2536|M.thermoresistible__bu --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK IALGQAQ
TH_2536|M.thermoresistible__bu -------
Mb1934c|M.bovis_AF2122/97 -------
Rv1899c|M.tuberculosis_H37Rv -------
MMAR_2794|M.marinum_M -------
MUL_2958|M.ulcerans_Agy99 -------
Mvan_5241|M.vanbaalenii_PYR-1 -------