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VPRCILGSVLTITAVRGDITEQEVDAVVNPANTAMRGGGGADGAIHRAGGPAILRDCVKRFPDGLATGDA GWTTAGDLPAQWVIHTVGPNYDTGQRNRSLLESCYRRALKVADELGARIVAFPLISTGSFGWPRQDAIAA AIETIAAADTRVDEARLVAFDPKTHEEIRSALATWTPIRILQGVQVLHQRGYHRIRVWPGVSPSGMYWRV AINTAGHLTDEGYPEVGDYDTAVLYPTGSLNELAGNEVTVTTRPEMVADLILEQLPEAAPTGDDPAYVSW FAELMRLVEQFQLPPIAYAEYFDASAGWEIGWGSGNRHPCPPKPAITTRRRSAPMPSLPSTSMSDNTANA LYRLETILQKATGLSPKVSAVEGTLIPRGDPLLPGVTIKFAATHARGADRAALFFDDKNVHLGVWPAELQ PQYTYVYSDPARVEALLDLDTHGDFTVEPNFQLAHRFAQPLQRWFPTRLLSAEDYLQQWVDDFHDGRAGG RTRDELADPGFFQWLAERRYASAAEEESLHHWLDSKKAGIQFHVRPGVQILRTWLYEEAFAIEGQNEFAV QVRNATNQILIALGQAQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3185 | - | - | 100% (577) | appr-1-p processing domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1934c | lppD | 3e-19 | 39.23% (130) | lipoprotein LppD |
| M. tuberculosis H37Rv | Rv1899c | lppD | 3e-19 | 39.23% (130) | lipoprotein LppD |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2794 | lppD | 2e-19 | 37.96% (137) | lipoprotein LppD |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2536 | - | 3e-71 | 78.26% (161) | PUTATIVE Appr-1-p processing domain protein |
| M. ulcerans Agy99 | MUL_2958 | lppD | 7e-20 | 38.69% (137) | lipoprotein LppD |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 MSRAAGLPRLSWFAGLTWFAGGSTGAGCAAHPALAGLTAGARCPAYAAIS
Rv1899c|M.tuberculosis_H37Rv MSRAAGLPRLSWFAGLTWFAGGSTGAGCAAHPALAGLTAGARCPAYAAIS
Mflv_3185|M.gilvum_PYR-GCK --------------------------------------------------
TH_2536|M.thermoresistible__bu --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 ASTARPAATALPAVAASTARPAATAGTTPATGASGSARPTDAAGMADLAR
Rv1899c|M.tuberculosis_H37Rv ASTAR---------------PAATAGTTPATGASGSARPTDAAGMADLAR
Mflv_3185|M.gilvum_PYR-GCK --------------------------------------------------
TH_2536|M.thermoresistible__bu --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 PGVVATHAVRTLGTTGSRAIGLCPCQPLDCPRSPQATPNLGSMGRSLDGP
Rv1899c|M.tuberculosis_H37Rv PGVVATHAVRTLGTTGSRAIGLCPCQPLDCPRSPQATLNLGSMGRSLDGP
Mflv_3185|M.gilvum_PYR-GCK --------------------------------------------------
TH_2536|M.thermoresistible__bu --------------------------------------------------
MMAR_2794|M.marinum_M -------------------------------------MIELEVVQADVTK
MUL_2958|M.ulcerans_Agy99 -------------------------------------MIELEVVQADVTK
Mb1934c|M.bovis_AF2122/97 QWRRARVRLCGRWWRRSNTTRGASPRPPSTCRGDNVSMIELEVHQADVTK
Rv1899c|M.tuberculosis_H37Rv QWRRARVRLCGRWWRRSNTTRGASPRPPSTCRGDNVSMIELEVHQADVTK
Mflv_3185|M.gilvum_PYR-GCK -----------------------------MPRCILGSVLTITAVRGDITE
TH_2536|M.thermoresistible__bu -----------------------------MP--------IITAVQGDITK
: . :.*:*:
MMAR_2794|M.marinum_M LELDAITNAANTQLRHAGGVAAAISRAGGPDIQRESNEKAPIGLG--EAV
MUL_2958|M.ulcerans_Agy99 LELDAITNAANTQLRHAGGVAAAISRAGGPDIQRESNEKAPIGLG--EAV
Mb1934c|M.bovis_AF2122/97 LELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTEKAPIGLG--EAV
Rv1899c|M.tuberculosis_H37Rv LELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTEKAPIGLG--EAV
Mflv_3185|M.gilvum_PYR-GCK QEVDAVVNPANTAMRGGGGADGAIHRAGGPAILRDCVKRFPDGLATGDAG
TH_2536|M.thermoresistible__bu QTVDAIVNAANRAMRGGGGVDGAIHRAGGPAILRDCIERFPDGLATGDAG
:**:.*.** :* .**. .** ***** : *:. :: * **. :*
MMAR_2794|M.marinum_M ETTAGEMPARYVIHAATMELG-GPTSSEIISRATSSALRKADELGCRSLA
MUL_2958|M.ulcerans_Agy99 ETTAGEMPARYVIHAATMELG-GPTSSELISRATSSALRKADELGCRSLA
Mb1934c|M.bovis_AF2122/97 ETTAGDMPARYVIHAATMELG-GPTSGEIITAATAATLRKADELGCRSLA
Rv1899c|M.tuberculosis_H37Rv ETTAGDMPARYVIHAATMELG-GPTSGEIITAATAATLRKADELGCRSLA
Mflv_3185|M.gilvum_PYR-GCK WTTAGDLPAQWVIHTVGPNYDTGQRNRSLLESCYRRALKVADELGARIVA
TH_2536|M.thermoresistible__bu WTTAGDLAARWVIHTVGPNYRAGERDRSLLESCYRRSLEVADELGAATVA
****::.*::***:. : * . .:: . :*. *****. :*
MMAR_2794|M.marinum_M LVAFGTGVGGFPLERAARLMVEAVRRHHPGSLKRVVFAVHGNAAEKAFVA
MUL_2958|M.ulcerans_Agy99 LVAFGTGVGGFPLERAARLMVEAVRRHHPGSLKRVVFAVHGNAAEKAFVA
Mb1934c|M.bovis_AF2122/97 LVAFGTGVGGFPLDDAARLMVGAVRRHRPGSLQRVVFAVHGDAAERAFSA
Rv1899c|M.tuberculosis_H37Rv LVAFGTGVGGFPLDDAARLMVGAVRRHRPGSLQRVVFAVHGDAAERAFSA
Mflv_3185|M.gilvum_PYR-GCK FPLISTGSFGWPRQDAIAAAIETIAAADTRVDEARLVAFDPKTHEEIRSA
TH_2536|M.thermoresistible__bu FPLISSGIYGWPRHDAIAAAIETIGLADARVEEARIVAFDLDTYEAVRTQ
: :.:* *:* . * : :: . : :.*.. .: *
MMAR_2794|M.marinum_M AVQA----------------------------------------------
MUL_2958|M.ulcerans_Agy99 AVQA----------------------------------------------
Mb1934c|M.bovis_AF2122/97 AIQAGEDTARR---------------------------------------
Rv1899c|M.tuberculosis_H37Rv AIQAGEDTARR---------------------------------------
Mflv_3185|M.gilvum_PYR-GCK LATWTPIRILQGVQVLHQRGYHRIRVWPGVSPSGMYWRVAINTAGHLTDE
TH_2536|M.thermoresistible__bu LEQRT---------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK GYPEVGDYDTAVLYPTGSLNELAGNEVTVTTRPEMVADLILEQLPEAAPT
TH_2536|M.thermoresistible__bu --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK GDDPAYVSWFAELMRLVEQFQLPPIAYAEYFDASAGWEIGWGSGNRHPCP
TH_2536|M.thermoresistible__bu --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK PKPAITTRRRSAPMPSLPSTSMSDNTANALYRLETILQKATGLSPKVSAV
TH_2536|M.thermoresistible__bu --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK EGTLIPRGDPLLPGVTIKFAATHARGADRAALFFDDKNVHLGVWPAELQP
TH_2536|M.thermoresistible__bu --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK QYTYVYSDPARVEALLDLDTHGDFTVEPNFQLAHRFAQPLQRWFPTRLLS
TH_2536|M.thermoresistible__bu --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK AEDYLQQWVDDFHDGRAGGRTRDELADPGFFQWLAERRYASAAEEESLHH
TH_2536|M.thermoresistible__bu --------------------------------------------------
MMAR_2794|M.marinum_M --------------------------------------------------
MUL_2958|M.ulcerans_Agy99 --------------------------------------------------
Mb1934c|M.bovis_AF2122/97 --------------------------------------------------
Rv1899c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3185|M.gilvum_PYR-GCK WLDSKKAGIQFHVRPGVQILRTWLYEEAFAIEGQNEFAVQVRNATNQILI
TH_2536|M.thermoresistible__bu --------------------------------------------------
MMAR_2794|M.marinum_M ------
MUL_2958|M.ulcerans_Agy99 ------
Mb1934c|M.bovis_AF2122/97 ------
Rv1899c|M.tuberculosis_H37Rv ------
Mflv_3185|M.gilvum_PYR-GCK ALGQAQ
TH_2536|M.thermoresistible__bu ------