For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. bovis AF2122 / 97 Mb1765c (narX)

annotation: nitrate reductase NarX
coordinates: 1947625 - 1949583
length: 652

VTVTPRTGSRIEELLARSGRFFIPGEISADLRTVTRRGGRDGDVFYRDRWSHHKVVRSTHGVNCTGSCSW
KIYVKDGIITWETQETDYPSVGPDRPEYEPRGCPRGAAFSWYTYSPTRVRHPYARGVLVEMYREAKARLG
DPVAAWADIQADPRRRRRYQRARGKGGLVRVSWAEATEMIAAAHVHTISTYGPDRVAGFSPIPAMSMVSH
AAGSRFVELIGGVMTSFYDWYADLPVASPQVFGDQTDVPESGDWWDVVWQCASVLLTYPNSRQLGTAEEL
LAHIDGPAADLLGRTVSELRRADPLTAATRYVDTFDLRGRATLYLTYWTAGDTRNRGREMLAFAQTYRST
DVAPPRGETPDFLPVVLEFAATVDPEAGRRLLSGYRVPIAALCNALTEAALPYAHTVAAVCRTGDMMGEL
FWTVVPYVTMTIVAVGSWWRYRYDKFGWTTRSSQLYESRLLRIASPMFHFGILVVIVGHGIGLVIPQSWT
QAAGLSEGAYHVQAVVLGSIAGITTLAGVTLLIYRRRTRGPVFMATTVNDKVMYLVLVAAIVAGLGATAL
GSGVVGEAYNYRETVSVWFRSVWVLQPRGDLMAEAPLYYQIHVLIGLALFALWPFTRLVHAFSAPIGYLF
RPYIIYRSREELVLTRPRRRGW
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1765cnarX-100% (652)nitrate reductase NarX
M. bovis AF2122 / 97Mb1193narGe-14485.05% (281) respiratory nitrate reductase subunit alpha NarG
M. bovis AF2122 / 97Mb1196narI7e-9668.20% (239) respiratory nitrate reductase subunit gamma NarI

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2156-1e-14389.58% (259) nitrate reductase, alpha subunit
M. tuberculosis H37RvRv1736cnarX0.099.69% (652) nitrate reductase NarX
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3041-3e-0527.94% (136) putative biotin sulfoxide reductase BisC
M. marinum M-----
M. avium 104MAV_1303-1e-13987.64% (259) nitrate reductase, alpha subunit
M. smegmatis MC2 155MSMEG_5140-1e-14091.97% (249) nitrate reductase, alpha subunit
M. thermoresistible (build 8)TH_1885narX1e-13988.03% (259) PROBABLE NITRATE REDUCTASE NARX
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4546-1e-14492.19% (256) nitrate reductase, alpha subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mb1765c|M.bovis_AF2122/97           MTVTPRTGSRIEELLARSGRFFIPGEISADLRTVTRRGGRDGDVFYRDRW
Rv1736c|M.tuberculosis_H37Rv        MTVTPRTGSRIEELLARSGRFFIPGEISADLRTVTRRGGRDGDVFYRDRW
Mflv_2156|M.gilvum_PYR-GCK          MSTPPRTGGVVEDLLARSGRFFTPGEFSDDLRTVTRRGGRDGDIFYRDRW
Mvan_4546|M.vanbaalenii_PYR-1       MTSPPRTGGVVEELLQRSGRFFTPGDFSEDLRTVTRRGGRDGDVFYRDRW
TH_1885|M.thermoresistible__bu      VTSPPRVGGPIEDLLQRSGRFFTPGDVSDDGRIVHRRGGREGDVFYRDRW
MSMEG_5140|M.smegmatis_MC2_155      ----------MEELLQRSGRFFTPGTFSSDLRTVSRQGGREGDVFYRDRW
MAV_1303|M.avium_104                MTATPHVGGVLEELLERSGRFFTPGEFSADLRTVTRQGGREADVFYRDRW
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1765c|M.bovis_AF2122/97           SHHKVVRSTHGVNCTGSCSWKIYVKDGIITWETQETDYPSVGPDRPEYEP
Rv1736c|M.tuberculosis_H37Rv        SHDKVVRSTHGVNCTGSCSWKIYVKDDIITWETQETDYPSVGPDRPEYEP
Mflv_2156|M.gilvum_PYR-GCK          SHDKVVRSTHGVNCTGSCSWKVYVKDGIITWETQETDYPSVGPDRPEYEP
Mvan_4546|M.vanbaalenii_PYR-1       SHDKVVRSTHGVNCTGSCSWKVYVKDGIITWETQETDYPSVGPDRPEYEP
TH_1885|M.thermoresistible__bu      SHDKVVRSTHGVNCTGSCSWKVYVKDGIITWETQETDYPSVGPDRPEYEP
MSMEG_5140|M.smegmatis_MC2_155      SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQETDYPSVGPDRPEYEP
MAV_1303|M.avium_104                SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQQTDYPSVGPDRPEYEP
MAB_3041|M.abscessus_ATCC_1997      ----MIRPAFSAVQVSGSARLSHTHWGAFTPEVRDGEVIGVTPIETDLDP
                                        ::*.:...  ....:   :.: . :* *.:: :  .* * ..: :*

Mb1765c|M.bovis_AF2122/97           RGCPRGAAFSWYTYSPTRVRHPYARGVLVEMYREAKARLGDPVAAWADIQ
Rv1736c|M.tuberculosis_H37Rv        RGCPRGAAFSWYTYSPTRVRHPYARGVLVEMYREAKARLGDPVAAWADIQ
Mflv_2156|M.gilvum_PYR-GCK          RGCPRGAAFSWYTYSPTRVRYPYARGVLVEMYREAKARIGDPVLAWADIQ
Mvan_4546|M.vanbaalenii_PYR-1       RGCPRGAAFSWYTYSPTRVRYPYARGVLVEMYREAKARLGDPVLAWADIQ
TH_1885|M.thermoresistible__bu      RGCPRGAAFSWYTYSPTRVRYPYARGVLVEMYREAKARLTDPVLAWADIQ
MSMEG_5140|M.smegmatis_MC2_155      RGCPRGAAFSWYTYSPTRVRYPYARGVLVEMYREARARLGDPVLAWADIQ
MAV_1303|M.avium_104                RGCPRGASFSWYSYSPTRVRYPYARGVLVEMYREAKARLGDPVLAWADIQ
MAB_3041|M.abscessus_ATCC_1997      S--------------------PLLQNIPGSIRHQARVTAPAVRSGWLREG
                                                         *  :.:  .: ::*:.       .*    

Mb1765c|M.bovis_AF2122/97           ADPRRRRRYQRARGKGGLVRVSWAEATEMIAAAHVHTISTYGPDRVAGFS
Rv1736c|M.tuberculosis_H37Rv        ADPRRRRRYQRARGKGGLVRVSWAEATEMIAAAHVHTISTYGPDRVAGFS
Mflv_2156|M.gilvum_PYR-GCK          ADPQRRRRYQQARGKGGLVRVTWAEATEMIAAAHVHTVKTYGPDRVAGFS
Mvan_4546|M.vanbaalenii_PYR-1       ADPQRRRRYQQARGKGGLVRVTWAEATEMIAAAHVHTIKTYGPDRVAGFS
TH_1885|M.thermoresistible__bu      ADPQRRRRYQQARGKGGLVRISWAEATEMIAAAHVHTIKTHGPDRVAGFS
MSMEG_5140|M.smegmatis_MC2_155      ADPERRRRYQSARGKGGLVRVSWAEATEMIAAAHVHTIKTYGPDRIAGFS
MAV_1303|M.avium_104                ADPERRRRYQRARGKGGLVRITWAEATELIAAAHVHTIKTYGPDRVAGFS
MAB_3041|M.abscessus_ATCC_1997      PGPSDKR------GADEYVEVSWDELTELLADELRRVVDTHGNEAIYGGS
                                    ..*  :*      * .  *.::* * **::*    :.:.*:* : : * *

Mb1765c|M.bovis_AF2122/97           PIPAMSMVSHAAG---SRFVELIGGVMTSFYDWYADLP-VASPQVFGDQT
Rv1736c|M.tuberculosis_H37Rv        PIPAMSMVSHAAG---SRFVELIGGVMTSFYDWYADLP-VASPQVFGDQT
Mflv_2156|M.gilvum_PYR-GCK          PIPAMSMVSHAAG---ARFVSLIGGAMTSFYDWYADLP-VASPQVFGDQT
Mvan_4546|M.vanbaalenii_PYR-1       PIPAMSMVSHAAG---SRFVELVGGAMTSFYDWYADLP-VASPQVFGDQT
TH_1885|M.thermoresistible__bu      PIPAMSMVSFAAG---SRFIELLGGVMTSFYDWYADLP-VASPQVFGDQT
MSMEG_5140|M.smegmatis_MC2_155      PIPAMSMVSHAAG---SRFVELIGGVMTSFYDWYADLP-VASPQVFGDQT
MAV_1303|M.avium_104                PIPAMSMVSYTAG---SRFFELIGAPMTSFYDWYADLP-VASPQVFGDQT
MAB_3041|M.abscessus_ATCC_1997      YGWASAGRFHHAQSQVHRFLKLLGGYTFSRHSYSLGATGVIMPHVIGTHD
                                       * :   . *     **..*:*.   * :.:  . . *  *:*:* : 

Mb1765c|M.bovis_AF2122/97           DVPESGDWWDVVW---------------------------QCASVLLTYP
Rv1736c|M.tuberculosis_H37Rv        DVPESGDWWDVVW---------------------------QCASVLLTYP
Mflv_2156|M.gilvum_PYR-GCK          DVPESGDWWDATYLMMWGSNVPVTRTPDAHWMAEVRYRGTKVVSVSPDYA
Mvan_4546|M.vanbaalenii_PYR-1       DVPESGDWWDASYLMMWGSNVPVTRTPDAHWMAEVRYRGTKVVSVSPDYA
TH_1885|M.thermoresistible__bu      DVPESGDWWDAAYLMMWGSNVPVTRTPDAHWMAEVRYRGTKVVAVSPDYA
MSMEG_5140|M.smegmatis_MC2_155      DVPESGDWWDAAYLMMWGSNVPVTRTPDAHWMAEVRYRGTKVVSVSPDYA
MAV_1303|M.avium_104                DVPESGDWWDAAYLMMWGSNVPITRTPDAHWMAEARYRGTKVVTVSPDYA
MAB_3041|M.abscessus_ATCC_1997      GLFKRSTSWDVIVEN---TDLLIAFGGIALKNTGVNHGGTTAHPARDALN
                                    .: : .  **.                                ..     

Mb1765c|M.bovis_AF2122/97           NSRQLG------------------------------------------TA
Rv1736c|M.tuberculosis_H37Rv        NSRQLG------------------------------------------TA
Mflv_2156|M.gilvum_PYR-GCK          DNTKFADEWMPCAAGTDGALAMAMGHVILTENYVRQRVPFFDEYVRTYTD
Mvan_4546|M.vanbaalenii_PYR-1       DNTKFADEWMPCAAGTDGALAMAMGHVILTENFVRRRVPFFVDYVRTYTD
TH_1885|M.thermoresistible__bu      DNTKFADEWMPCAAGTDGAMAMAMGHVILSEFFVRKQVPFFTDYVRRYTD
MSMEG_5140|M.smegmatis_MC2_155      DNTKFADEWMPCAAGTDGALAMAMGHVILSECFVQNEVPYFTDFARRFTD
MAV_1303|M.avium_104                DNTKFADEWMPCAAGTDGALAMAMGHVILSECYVQKQVPFFTDYARRYTD
MAB_3041|M.abscessus_ATCC_1997      RFRDRGGRIVSFSPLHDDIDGECEWHAPIPG-----------------TD
                                       . .                                          * 

Mb1765c|M.bovis_AF2122/97           EELLAHIDG-----------PAADLLG-----------------------
Rv1736c|M.tuberculosis_H37Rv        EELLAHIDG-----------PAADLLG-----------------------
Mflv_2156|M.gilvum_PYR-GCK          LPFLVKLEERGGVTVPGKMLTAADLGPAYGG-ENAEFKPALLNLATDSVT
Mvan_4546|M.vanbaalenii_PYR-1       LPFLVKLEERDGVLVPGKMLTAADLGPGYDGQENAAFKPVLLDGATDSVV
TH_1885|M.thermoresistible__bu      LPFLVKLEERDGALVPGKMLTVADLGEVFGQHENAAFKPMLLDEATDTVT
MSMEG_5140|M.smegmatis_MC2_155      LPFLAKLEERDGALVPGKNLTAADLTPDVAAQENAAFKPALLDSASDSIA
MAV_1303|M.avium_104                LPFLIKLEERGDMLVPGKNLTAADLG---EAVENAALKPALLDETTNSVA
MAB_3041|M.abscessus_ATCC_1997      VAVMLALAHVLAVEKLADLTFLSSYCTGYERFERYLLG------------
                                      .:  :               :.                          

Mb1765c|M.bovis_AF2122/97           --------------------------------------------------
Rv1736c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_2156|M.gilvum_PYR-GCK          VPPGSLGFRYGDEGVGRWNLDLGDVVPALTVATGDVHDGGSAAVTLSRFD
Mvan_4546|M.vanbaalenii_PYR-1       VPPGSLGFRYGDEGVGKWNLDLGDVVPALTVAPPDGQSGETTSISLTRFD
TH_1885|M.thermoresistible__bu      VPHGSLGFRYGTDGAGKWNLDLGPVVPALTVRTGD---GPVTEVRLPCFD
MSMEG_5140|M.smegmatis_MC2_155      IPQGSLGFRFGESGLGNWNLDLENLAPALTVAADT---GETAEVTLPRFD
MAV_1303|M.avium_104                VPHGSLGFRYGESGVGKWNLDLGDLVPALSVRAAPTEDGETALVHLPSFD
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1765c|M.bovis_AF2122/97           --------------------------------------------------
Rv1736c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_2156|M.gilvum_PYR-GCK          TVDGHGATMLRGVPVRQVGAHRVCTVFDLMLAQYGVARPGLPGDWPTGYD
Mvan_4546|M.vanbaalenii_PYR-1       TVDGRGATLQRGVPVRRVGEHRVCTVFDLMLAQYGVARPGLPGDWPAGYD
TH_1885|M.thermoresistible__bu      SVDGHGTTVTRGVPVRHVGDHRVCTVFDLMLAQYGVSRPGLPGDWPTGYD
MSMEG_5140|M.smegmatis_MC2_155      TLDGHGDTMVRGVPVRRVGEHLVCTVFDLMLAQYGVARPGLPGDWPTGFD
MAV_1303|M.avium_104                TVDGEGTTVARGVPVRRVGKHLVCTVFDLMLAQYGVARPGLPGEWPTGYD
MAB_3041|M.abscessus_ATCC_1997      -------------------------------------------------V
                                                                                      

Mb1765c|M.bovis_AF2122/97           -----------RTVSELRRADPLTAATRYVDTFDLRG-------------
Rv1736c|M.tuberculosis_H37Rv        -----------RTVSELRRADPLTAATRYVDTFDLRG-------------
Mflv_2156|M.gilvum_PYR-GCK          DPRSPYTPAWQEPITGVSAGQAIRVAREFARNAEESGGRSMIIMGAGICQ
Mvan_4546|M.vanbaalenii_PYR-1       DPDQPYTPAWQESITGVSASQAIRVAREFARNAEESGGRSMIIMGAGICQ
TH_1885|M.thermoresistible__bu      DATRPYTPAWQEPITGVSAAQVIRIATEFARNAEESGGRSMIIMGAGICQ
MSMEG_5140|M.smegmatis_MC2_155      DATRPYTPAWQEPITGVAAAQAIRVAREFARNAEETRGRSMIIMGAGICQ
MAV_1303|M.avium_104                DATQQNTPAWQEAITGVSAAQATRVAREFARSAEESGGRSMIIMGGGICH
MAB_3041|M.abscessus_ATCC_1997      DDGVPKSPEWAAPISGLDAAELRTLARRMAAGR------TLVTVSWSLQR
                                                .:: :  .:    * . .                    

Mb1765c|M.bovis_AF2122/97           --------RATLYLTYWTAGDTRNRG-----------REMLAFAQTYRST
Rv1736c|M.tuberculosis_H37Rv        --------RATLYLTYWTAGDTRNRG-----------REMLAFAQTYRST
Mflv_2156|M.gilvum_PYR-GCK          WFHGDTTYRAVLAMLLLTGSMGRNGGGWAHYVGQEKCRPVTGWATMGSAL
Mvan_4546|M.vanbaalenii_PYR-1       WFHGDTTYRAVLAMLLLTGSMGRNGGGWAHYVGQEKCRPVTGWATMAMAT
TH_1885|M.thermoresistible__bu      WFHGDATYRAVLALLLLTGSMGRNGGGWAHYVGQEKCRPVTGWATMAMAT
MSMEG_5140|M.smegmatis_MC2_155      WFHGDATYRAVLALLLLTGSMGRNGGGWAHYVGQEKCRPVTGWATMAMAT
MAV_1303|M.avium_104                WFHSDAIYRAVLALLMLTGSMGRNGGGWAHYVGQEKVRPLTGFQTMAMAT
MAB_3041|M.abscessus_ATCC_1997      VRHGEQAPWMGLTLAAMLGQIGLPGGGFGHGYGSMNEPGLAPVSCPLPTF
                                               * :    .      *             :        : 

Mb1765c|M.bovis_AF2122/97           DVAPPRGETP----------------------------------------
Rv1736c|M.tuberculosis_H37Rv        DVAPPRGETP----------------------------------------
Mflv_2156|M.gilvum_PYR-GCK          DWSRPPRQMPGTSYWYAHTDQWRYDGYRADTLASPTARGRFTGKHTMDVV
Mvan_4546|M.vanbaalenii_PYR-1       DWTRPPRQMPGTSYWYAHTGQWRYDGYRADALASPTARGRFAGKHTMDVV
TH_1885|M.thermoresistible__bu      DWSRPPRQMPGTSYWYVHTDQWNYDGYRADALASPIGRGRFRGKHTMDVL
MSMEG_5140|M.smegmatis_MC2_155      DWSRPPRQMAGTSYWYAHTDQWRYDGYQADALSSPVGRGRFRGRHTMDVL
MAV_1303|M.avium_104                DWVRPPRQVPGASYWYAHTDQWRYDGYGADKLASPVGRGRFAGRHTMDLL
MAB_3041|M.abscessus_ATCC_1997      PQGPNPVETFIP--------------------------------------
                                           :                                          

Mb1765c|M.bovis_AF2122/97           ------DFLPVVLEFA--------------------------------AT
Rv1736c|M.tuberculosis_H37Rv        ------DFLPVVLEFA--------------------------------AT
Mflv_2156|M.gilvum_PYR-GCK          AAAAAMGWMPFYPQFDRNSLDIADEALAAGRDIPQYLCEKLASGELKMAV
Mvan_4546|M.vanbaalenii_PYR-1       AAAAAMGWMPFYPQFDRNSLDVADEARAAGQDIGKYVCEKLASGELKMAV
TH_1885|M.thermoresistible__bu      ASATAMGWSPFYPQFDRSSLDIADEARAAGKEIGAYVCEQLASGGLKLAV
MSMEG_5140|M.smegmatis_MC2_155      ASAAAMGWSPFFPQFDRSSLDVADEARAADQEIPAYVTAKLADGSLKLAV
MAV_1303|M.avium_104                ASAVAMGWSPYYPQFDRSSLDVADEARAAGRDVADYVAEQLGRRNLKLAV
MAB_3041|M.abscessus_ATCC_1997      ----VAAISELLLRPGQ-------------------------------TL
                                                 .                                  : 

Mb1765c|M.bovis_AF2122/97           VDPEAGR---RLLSGYRVPIAALCN-------------------------
Rv1736c|M.tuberculosis_H37Rv        VDPEAGR---RLLSGYRVPIAALCN-------------------------
Mflv_2156|M.gilvum_PYR-GCK          TDPDNPANWPRVLNVWRANLLGSSSKGNEYFLRHLLGTDSNLQASPTPEA
Mvan_4546|M.vanbaalenii_PYR-1       TDPDNPANWPRVLNVWRANLLGSSSKGNEYFLRHLLGADSNLQATPTEEA
TH_1885|M.thermoresistible__bu      TDPDDPRNWPRVLSVWRSNLLGSSSKGNEYFLRHLLGTDSNLRATRTPEA
MSMEG_5140|M.smegmatis_MC2_155      TDPDNPANWPRVLDVWRANLLGSSSKGNEYFLRHLLGTTSNLQAAPN--G
MAV_1303|M.avium_104                TDPDNPVNWPRVLTVWRANLIGSSGKGGEYFLRHLLGTDSNASAVPPEDG
MAB_3041|M.abscessus_ATCC_1997      AYNGQTLTLPDIRCVYWAGGNPFHHHQNLPRLRR----------------
                                    .          :   :                                  

Mb1765c|M.bovis_AF2122/97           ----------ALTEAALPYAHTVAAVCRTGDMMGELFWTVV---------
Rv1736c|M.tuberculosis_H37Rv        ----------ALTEAALPYAHTVAAVCRTGDMMGELFWTVV---------
Mflv_2156|M.gilvum_PYR-GCK          LRPADVVWPDDIPEGKLDLLMSIDFRMTSTTLLSDVVLPAATWYEKADLS
Mvan_4546|M.vanbaalenii_PYR-1       LRPKDVTWPDDIPEGKLDLLMSVDFRMTSTTLLSDVVLPAATWYEKADLS
TH_1885|M.thermoresistible__bu      LRPNDVRSPDEIPEGKLDLLMSIDFRMTSTTLLSDIVLPAATWYEKHDLS
MSMEG_5140|M.smegmatis_MC2_155      VRPSSVTCTDDIPEGKLDLLMSIDFRMTSTTLLSDVVLPAATWYEKADLS
MAV_1303|M.avium_104                VRPVDVTCGADIPEGKLDLMMSIDFRMTSTTLVSDVVLPAATWYEKADIS
MAB_3041|M.abscessus_ATCC_1997      ------------ALSRVDTVVVHDPVWTAMAKHADIVVPSTTSLERDDFS
                                                . . :           :    .::. . .         

Mb1765c|M.bovis_AF2122/97           -----PYVTMTIVAVGSWWRYR--YDKFGWTTRSS---------------
Rv1736c|M.tuberculosis_H37Rv        -----PYVTMTIVAVGSWWRYR--YDKFGWTTRSS---------------
Mflv_2156|M.gilvum_PYR-GCK          STDMHPYVHAFSPAIDPPWETRSDFDAFGAVASAFSALARTHLGTRTDVV
Mvan_4546|M.vanbaalenii_PYR-1       STDMHPYVHAFSPAIDPPWETRSDFEAFGAIARTFSTLARSHLGTRTDVV
TH_1885|M.thermoresistible__bu      STDMHPYVHAFSPAIDPPWETRSDYDAFGAIARAFSALARKHLGTRTDVV
MSMEG_5140|M.smegmatis_MC2_155      STDMHPYVHAFSPAVDPPWETRSDFEAFGAIARAFSTLAARHLGVRTDVV
MAV_1303|M.avium_104                STDMHPYVHAFSAATDPPWETRSDFDAFGAIARAFSTMAKEHLGTRTDVV
MAB_3041|M.abscessus_ATCC_1997      GSRNDPLLVAMKAVAPPYANSRDDYTTFSALADRLGFG------------
                                         * :     .  .  . *  :  *.  :                  

Mb1765c|M.bovis_AF2122/97           --------------------------------------QLYESRLLRIAS
Rv1736c|M.tuberculosis_H37Rv        --------------------------------------QLYESRLLRIAS
Mflv_2156|M.gilvum_PYR-GCK          LGALQHDTPGAMAYPAGTQRDWRETGEVPVPGATIGPIAVVERDYTAIAD
Mvan_4546|M.vanbaalenii_PYR-1       LGALQHDTPGAMAYPAGTQRDWRETGETPVPGKTIGPITVVERDYAAIAD
TH_1885|M.thermoresistible__bu      LGALQHDTPGAMAYAGGTERDWRVTGEVPVPGKTIGPLAVVERDYTAIAD
MSMEG_5140|M.smegmatis_MC2_155      LGTLQHDTLGAMAYPSGTEHDWRVTGETPVPGRTMGPLAVVERDYGAIAQ
MAV_1303|M.avium_104                LTALQHDTPDAMAYPDGAEHDWLRSGATPVPGRTMGKLTVVERDYAAVYD
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------EQFSEGRTAAQW
                                                                             .        

Mb1765c|M.bovis_AF2122/97           PMFHFGILVVIVGHGIGLVIPQSWTQAAGLSEGAYHVQAVVLGSIAGITT
Rv1736c|M.tuberculosis_H37Rv        PMFHFGILVVIVGHGIGLVIPQSWTQAAGLSEGAYHVQAVVLGSIAGITT
Mflv_2156|M.gilvum_PYR-GCK          KWSTLGPLVEKLGLTTKGVTTHPDREADELARKFGVFDSGPAAGRPAITT
Mvan_4546|M.vanbaalenii_PYR-1       KWSTLGPLVERLGVTTKGVTTWPVQETAELAQKFGVLDSGPAAGQPAITT
TH_1885|M.thermoresistible__bu      KWAALGPLVEELGVTTKGVTTWPVQEVAELAKAFGVMDSGPAAGRPAITT
MSMEG_5140|M.smegmatis_MC2_155      KWAALGPLVEGLGVTTKGLTTHPTREVAELGAKFGVMDSGAAQGRPAITT
MAV_1303|M.avium_104                KWRTLGPLVDKFGLTTKGVTVHPFREVEELAARFGVLKSGVAAGRPAITT
MAB_3041|M.abscessus_ATCC_1997      LRHIYTEWAGALNFSVPSFDEFWDRGYLELPTDAGLTLLSDFRENPAAHP
                                            .  ..     .          *               ..  .

Mb1765c|M.bovis_AF2122/97           LAGVTLLIY-------------------RRRTRGPVFMATTVNDKVMYLV
Rv1736c|M.tuberculosis_H37Rv        LAGVTLLIY-------------------RRRTRGPVFMATTVNDKVMYLV
Mflv_2156|M.gilvum_PYR-GCK          AERMADVILALSGTSNGRLAVEGFRELQRRTGTPLAHLAEGSEERRITYA
Mvan_4546|M.vanbaalenii_PYR-1       AERMADVILALSGTSNGRLAVEGFRELERRTGRPLAHLAEGSEERRITYA
TH_1885|M.thermoresistible__bu      AARMAEVILALSGTSNGRLAVEGFRELEKRTGQRLAQLAEGSEERRITFA
MSMEG_5140|M.smegmatis_MC2_155      GERMADVILALSGTSNGRLAVEGFAELERRTGRKLVHLALGSEERRITYA
MAV_1303|M.avium_104                AARMADVLLLLSGTTNGRLAVEGFHELEKRTGQRLVHLAEGSEDKRISYA
MAB_3041|M.abscessus_ATCC_1997      LHTPSGRIEIFSETIDGFGYSDCGG---HPQWYEPTEWLGGERAQRFPLH
                                        :  :                    :      .      . : :   

Mb1765c|M.bovis_AF2122/97           LVAAIVAGLGATALGSG--VVGEAYNYRETVSVWFRSVWVLQPRG-----
Rv1736c|M.tuberculosis_H37Rv        LVAAIVAGLGATALGSG--VVGEAYNYRETVSVWFRSVWVLQPRG-----
Mflv_2156|M.gilvum_PYR-GCK          DTQARPVPVITSPEWSGSETGGRRYAPFTVNIEQLKPFHTLTGRMHFYLD
Mvan_4546|M.vanbaalenii_PYR-1       DTQARPVPVITSPEWSGSETGGRRYAPFTVNIEALKPFHTLTGRMHFYLD
TH_1885|M.thermoresistible__bu      DTQARPVPVITSPEWSGSETAGRRYAPFTVNIEHLKPFHTLTGRMHFYLD
MSMEG_5140|M.smegmatis_MC2_155      DAQARPVPVITSPEWSGSETGGRRYAPFTVNIEELKPFHTLTGRMHFYVD
MAV_1303|M.avium_104                DTQARPVPVVTSPEWSGSETGGRRYAPFTINIENLKPFHTLTGRMHFYLA
MAB_3041|M.abscessus_ATCC_1997      LIANQPRTRLHSQLDFGGTSQGSKVRGREP--LRIHPQDAATRGIADGDV
                                               :    *    *            ::.  .          

Mb1765c|M.bovis_AF2122/97           -----DLMAEAPLY---YQIHVLIG----------------------LAL
Rv1736c|M.tuberculosis_H37Rv        -----DLMAEAPLY---YQIHVLIG----------------------LAL
Mflv_2156|M.gilvum_PYR-GCK          HDWLEELGEQLPVYRPPLDLGRLFGEPAIG----APGATGVGLTVRYLTP
Mvan_4546|M.vanbaalenii_PYR-1       HDWLEELGEQLPVYRPPLDMARLFGEPAIG----ARG--ELGLTVRYLTP
TH_1885|M.thermoresistible__bu      HDWLEELGEQLPVYRPPLDMARLFGAQQIG----HSD--GVGLTVRYLTP
MSMEG_5140|M.smegmatis_MC2_155      HDWLEELGEQLPVYRPPLDMARLFGESRLGAGPGADGAGGVGLTVRYLTP
MAV_1303|M.avium_104                HDWVEELGEHLPVFRPPLDMARLFGQPRLG-----ACEDGIGLTVRYLTP
MAB_3041|M.abscessus_ATCC_1997      VRVFNDRGACLAGAVLDEGLRRQVVQLSTG---------------AWFDP
                                         :     .       :   .                       :  

Mb1765c|M.bovis_AF2122/97           FALWPFT-------------------------------------------
Rv1736c|M.tuberculosis_H37Rv        FALWPFT-------------------------------------------
Mflv_2156|M.gilvum_PYR-GCK          HSKWSIHSEYQDNLFMLSLSRGGPTMWMSPADAEKIEVRDNDWVEAVNRN
Mvan_4546|M.vanbaalenii_PYR-1       HSKWSIHSEYQDNLFMLSLSRGGPTMWMSPADAAKIQVRDNDWVEAVNRN
TH_1885|M.thermoresistible__bu      HSKWSIHSEYQDNLLMLSLSRGGPTMWMSPADAAKIGVADNDWVEAVNPN
MSMEG_5140|M.smegmatis_MC2_155      HSKWSIHSEYQDNLFMLSLSRGGPTMWMSPGDADKIAVRDNDWVEAVNRN
MAV_1303|M.avium_104                HSKWSFHSTYQDNLYMLSLSRGGPTMWMSPGDAAKIQVRDNDWVEAVNAN
MAB_3041|M.abscessus_ATCC_1997      IEPADPNSACAHG----------------------------------NPN
                                                                                      

Mb1765c|M.bovis_AF2122/97           -----RLVHAFSAPIGYLFRPYIIYR------------------------
Rv1736c|M.tuberculosis_H37Rv        -----RLVHAFSAPIGYLFRPYIIYR------------------------
Mflv_2156|M.gilvum_PYR-GCK          GVLVCRAIVSHRMPEGVVYVYHAQERTIDVPLTETTGRRGGIHNSLTRLL
Mvan_4546|M.vanbaalenii_PYR-1       GVLVCRAIVSHRMPEGVVYVYHAQERTIDVPLTETTGRRGGIHNSLTRLL
TH_1885|M.thermoresistible__bu      GVLVCRAIVSHRMPEGVVYVYHVQERTIDVPIAETTGKRGGIHNSLTRLL
MSMEG_5140|M.smegmatis_MC2_155      GVLVCRAIVSHRMPDGVVYVYHAQERTIDVPLTETTGTRGGIHNSLTRLL
MAV_1303|M.avium_104                GIYVCRAIVSHRMPDGVVYVYHVQERTVDTPRTETNDKRGGNHNALTRVR
MAB_3041|M.abscessus_ATCC_1997      VLTDDSGTSSLAQGCTGQHVLVQIERFEGTP-------------------
                                             :        .      *                        

Mb1765c|M.bovis_AF2122/97           -------------------------SREELVLTRPRRRGW---
Rv1736c|M.tuberculosis_H37Rv        -------------------------SREELVLTRPRRRGW---
Mflv_2156|M.gilvum_PYR-GCK          VKPSHLAGGYAQTAFAFNYLGPTGNQRDEVTVVRRRSQEVVY-
Mvan_4546|M.vanbaalenii_PYR-1       VKPSHLAGGYAQTAFAFNYLGPTGNQRDEVTIVRRRSQEVVYQ
TH_1885|M.thermoresistible__bu      IKPSHLAGGYAQNAFAFNYLGPTGNQRDEVTVVRRRSQRVVF-
MSMEG_5140|M.smegmatis_MC2_155      IKPSHLAGGYAQHSYAFNYLGPTGNQRDEVTVVRRRSQEVTYR
MAV_1303|M.avium_104                IKPSHLAGGYAQHAFAFNYLGPTGNQRDEVTIVRRRSQEVVY-
MAB_3041|M.abscessus_ATCC_1997      ------------------------PPVRAHTPPRFVARD----
                                                                  .  *   :