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MTNVGDQGVDAVFGVIYPPQVALVSFGKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDHRGALFFLSIN ELTRCAAVAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1763c | - | - | 100% (80) | hypothetical protein Mb1763c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1734c | - | 2e-42 | 98.75% (80) | hypothetical protein Rv1734c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4916c | - | 7e-06 | 30.56% (72) | putative dihydrolipoamide acyltransferase component |
| M. marinum M | MMAR_3491 | - | 4e-27 | 73.61% (72) | pyruvate dehydrogenase (E2 component) |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1410 | - | 1e-26 | 72.22% (72) | branched-chain alpha-keto acid dehydrogenase subunit E2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1763c|M.bovis_AF2122/97 --------------------------------------------------
Rv1734c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3491|M.marinum_M --MIEFKMPALGSDMDEGTLNEWLVKPGDKVSRGQIVAIVETTKAAVEIE
Mvan_1410|M.vanbaalenii_PYR-1 --MIEFAMPALGSDMDEGMLNEWLVKPGDTVSRGQVVAVVETTKAAVEIE
MAB_4916c|M.abscessus_ATCC_199 MAVKQFLLPDLGEGLTEADLISWKVRVGDEVKLNQVLADVETAKAMVELP
Mb1763c|M.bovis_AF2122/97 --------------------------------------------------
Rv1734c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3491|M.marinum_M CWQEGTVDELVVPVGDTVEVGTVLATLLEPG----ASPQRSPRQ------
Mvan_1410|M.vanbaalenii_PYR-1 CWHDGTVHELLVPVGQTVSVGTPLATLLESGEVAAEHPAVSPKQPAAAPS
MAB_4916c|M.abscessus_ATCC_199 SPFEGTVVALQAAENSTVAVGAPLISIEVAGAEPDAPANLVGYGPSDSAG
Mb1763c|M.bovis_AF2122/97 --------------------------------------------------
Rv1734c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3491|M.marinum_M -------------------------RPRKRATPAPTVAAS---APAPAHG
Mvan_1410|M.vanbaalenii_PYR-1 EQPAAVSSEQPAAVAPGRPAAVSSGRPAAVSSGRPAAVSSGRPAAVSSGR
MAB_4916c|M.abscessus_ATCC_199 ------------------QTRRRRRSGAGAAALALVEQTTEPEPAVAAPA
Mb1763c|M.bovis_AF2122/97 --------------------------------------------------
Rv1734c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3491|M.marinum_M ATAAPR-HRRWVSPAARRLAQSLHVDLDAVSGTGPQGAVTISDVEHAAAS
Mvan_1410|M.vanbaalenii_PYR-1 PAAVPSGHRRWVSPAARRLASSLHVDLDAVTGTGPQGAVTITDVEHAAAE
MAB_4916c|M.abscessus_ATCC_199 AQAESVPSRAAAKPSVRKLAAELGVALELINGTGIGGSITRQDVEAYTRS
Mb1763c|M.bovis_AF2122/97 --------------------------------------------------
Rv1734c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3491|M.marinum_M AVPAKRPAATAASTSAKSIGAKSTAQNKIAERAAQMRKSIAAAMSRSKRE
Mvan_1410|M.vanbaalenii_PYR-1 AAGSAAETARPAAETAGPAAAKPAES-----RGAMMRRSIAAAMGRSKRE
MAB_4916c|M.abscessus_ATCC_199 LTARAPQGAPAEEEPVAGVAVQPGGETRIP--IAGVRKHTAAAMVRSAFT
Mb1763c|M.bovis_AF2122/97 --------------------------------------------------
Rv1734c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3491|M.marinum_M IPHYYLADEILMEKSLNWLTTRNAQRSITERVLPAVLLLKAVGLAAQRFG
Mvan_1410|M.vanbaalenii_PYR-1 IPHYYLANEILLDASSQWLAERNAQRSITERVLPAALLLKAVGVAAQRFQ
MAB_4916c|M.abscessus_ATCC_199 APHVTEFLTVDMTSTMGLLAELKAK-SPDLKLTPMTLVARMVLLALRSHP
Mb1763c|M.bovis_AF2122/97 --------------------------------------------------
Rv1734c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3491|M.marinum_M EFNGFWRDDGFQAATGVHVGVGISLRGG-GLVAPAIHDVADKKLDELMGD
Mvan_1410|M.vanbaalenii_PYR-1 ELNGFWRDDGFVPADAVHVGVGISLRGG-GLVAPAIHDVPGKKLDEVMSE
MAB_4916c|M.abscessus_ATCC_199 SLNSAWDEQAGEIIVKHYVNLGIAAATERGLVVPNVKGADAMSLGELATA
Mb1763c|M.bovis_AF2122/97 ------------------------MTNVGDQGVDAVFGVIYPPQVALVSF
Rv1734c|M.tuberculosis_H37Rv ------------------------MTNVGDQGVDAVFGVIYPPQVALVSF
MMAR_3491|M.marinum_M LTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGVIYPPQVAIVGF
Mvan_1410|M.vanbaalenii_PYR-1 LTDLVARARAGSLRSSEMSDPTITVTNLGDQGVDTVFGIIYPPQVALVGF
MAB_4916c|M.abscessus_ATCC_199 IAQLVSTARAGKTAPTDMSGGTFTLTNIGVFGVDAGTPIINPGEAAILAL
:**:* ***: :* * :.*::.:
Mb1763c|M.bovis_AF2122/97 GKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDHRGALFFLSINELTRCA
Rv1734c|M.tuberculosis_H37Rv GKPAQRVCAVDGAIHVMTTVLATLPADHGCSDDHRGALFFLSINELTRCA
MMAR_3491|M.marinum_M GKPAQRVCVIDGGIRVVTTVQGTLAADHRASDGHRGALFLAAINELLQQP
Mvan_1410|M.vanbaalenii_PYR-1 GKPAQRVCAVDGGIRIATTVHATLAADHRASDGHRGAMFLAAIDQLLQQP
MAB_4916c|M.abscessus_ATCC_199 GSVAKRPWVVNGELAVRDVTTLALSFDHRLVDGEQGSKFLADLGAMLTDP
*. *:* .::* : : .. :*. ** *..:*: *: :. : .
Mb1763c|M.bovis_AF2122/97 AVAG--
Rv1734c|M.tuberculosis_H37Rv AVTG--
MMAR_3491|M.marinum_M DLLEK-
Mvan_1410|M.vanbaalenii_PYR-1 DQLEK-
MAB_4916c|M.abscessus_ATCC_199 RMALVV