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ASRSYGQYCALAKSLDLVGDRWTLLVVRELLDGPRRYGDLLSALSPIATDVLAGRLRDLEANNLVHKRAM PRPSATTVYALTADGRALEDVINAFARWGRHLLANRDRKETVRPEWLVRAVRAYVRDDRTGPPVTVRMVT PEGQAAVEINEHTVESLDDEADVDVTLTGAAEVLAAAMDPGQVENLVAAGLLTIDGDARAVRRLAKAFAP PRVRV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5032 | - | - | 100% (216) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2905 | - | 2e-12 | 38.71% (93) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6580 | - | 5e-12 | 35.77% (123) | transcriptional regulator family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1754c | - | 7e-15 | 41.18% (102) | hypothetical protein Mb1754c |
| M. gilvum PYR-GCK | Mflv_2233 | - | 1e-72 | 60.48% (210) | HxlR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1725c | - | 8e-15 | 41.18% (102) | hypothetical protein Rv1725c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3456 | - | 4e-11 | 35.16% (91) | HxlR family transcriptional regulator |
| M. marinum M | MMAR_1147 | - | 3e-23 | 32.17% (230) | transcriptional regulatory protein |
| M. avium 104 | MAV_4183 | - | 1e-05 | 29.41% (102) | putative transcriptional regulator family protein |
| M. thermoresistible (build 8) | TH_2405 | - | 5e-77 | 66.51% (215) | putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_0912 | - | 2e-23 | 31.08% (222) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1032 | - | 5e-30 | 37.16% (218) | HxlR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1754c|M.bovis_AF2122/97 ------------MQPYGQYCPVARAAELLGDRWTLLIVRELLFGPLRFTE
Rv1725c|M.tuberculosis_H37Rv ------------MQPYGQYCPVARAAELLGDRWTLLIVRELLFGPLRFTE
MSMEG_5032|M.smegmatis_MC2_155 ----------MASRSYGQYCALAKSLDLVGDRWTLLVVRELLDGPRRYGD
TH_2405|M.thermoresistible__bu ----------MASRTYGQHCALAKSLDLVGDRWTLLIVRELLDGPRRYSD
Mflv_2233|M.gilvum_PYR-GCK ----------MPTRSYRQYCAVAKSLDLVGDRWTLLIVRELLDGPQRYGD
MMAR_1147|M.marinum_M ----------MSARNYNQNCPIARGLDILGERWTLLILRELVGGPRRYGD
MUL_0912|M.ulcerans_Agy99 ----------MSARNYNQNCPIARGLDILGERWTLLILRELVGGPRRYGD
Mvan_1032|M.vanbaalenii_PYR-1 ----MSTIVGMTRRSYGQFCGLAHALDVVGERWTLLIVRELGSGPKRYGE
MAB_3456|M.abscessus_ATCC_1997 -----------MDFTTMRNCSISNALDVIGERWTLVALREIMLGNRRFET
MAV_4183|M.avium_104 MTLLQGPLADRDAWSAVGECAIEKTMAVVGTKSAMLIMREAYYGTTRFDD
* : . ::* : ::: :** * *:
Mb1754c|M.bovis_AF2122/97 IERGLPGISRSVLAQRLRRLQHDRIIEAV-PEHTGGG----YRFTVAGEE
Rv1725c|M.tuberculosis_H37Rv IERGLPGISRSVLAQRLRRLQHDRIIEAV-PEHTGGG----YRFTVAGEE
MSMEG_5032|M.smegmatis_MC2_155 LLSALSPIATDVLAGRLRDLEANNLVHK--RAMPRPSATTVYALTADGRA
TH_2405|M.thermoresistible__bu LLTALRPIATDMLATRLRHLEEHHLVRR--RELPKPASGTVYELTADGAA
Mflv_2233|M.gilvum_PYR-GCK LSAALSPIATDMLASRLRDMEAHGLLRK--HRMPKPASATVYEPTDEGRS
MMAR_1147|M.marinum_M LRAELAGIATNLLAQRLAELQERGLVDR--TELPPPIGRTVYTLSDGGWR
MUL_0912|M.ulcerans_Agy99 LRAELAGIATNLLAQRLAELQERGLVDR--TELPPPIGRTVYTLSDGGWR
Mvan_1032|M.vanbaalenii_PYR-1 LADALAGIGTSLLATRMRQLETDGVIQRR-LDLDQPGSAVVYELSDAGRE
MAB_3456|M.abscessus_ATCC_1997 IVRNTG-ASRDILATRLRKLVDAGVLEK--RRYEDRPPRYEYLLTQSGQA
MAV_4183|M.avium_104 FARRVG-ITKAATSARLAELVELGLLKRRPYREPGQRSRDEYVLTQAGID
: : *: : :: * : *
Mb1754c|M.bovis_AF2122/97 LRPVLQTLGDWVS--RWLMADPTPAECDPELLTLWISRRVNTEALPGRRV
Rv1725c|M.tuberculosis_H37Rv LRPVLQTLGDWVS--RWLMADPTPAECDPELLTLWISRRVNTEALPGRRV
MSMEG_5032|M.smegmatis_MC2_155 LEDVINAFARWG--RHLLANRDRKETVRPEWLVRAVRAYVRDDRTGPPVT
TH_2405|M.thermoresistible__bu LEAVVHAFIRWG--RSLLETRRAGDVVRPHWLARAVRAHVRPDRTGPPLS
Mflv_2233|M.gilvum_PYR-GCK LEGVVDALARWG--RRLVQTREPGDVLQPQWLARAVRAYIRDDRTGPPVV
MMAR_1147|M.marinum_M RVLPVLQTLAWFGLDLIDPIDDSSVVSPLNGFLAGILLGFDPARAPGLAA
MUL_0912|M.ulcerans_Agy99 RVLPVLQTLAWFGLDLIDPIDDSSVVSPLNGFLAGILLGFDPARAPGLAA
Mvan_1032|M.vanbaalenii_PYR-1 LAEAMIPLAMWGARHQMSHADPCAEAFRAEWLLAFLAADLRGGIPEGLAS
MAB_3456|M.abscessus_ATCC_1997 LRPVLFALMEWG----------------DKFVTKGPPPSIWEHQCG---S
MAV_4183|M.avium_104 FMPVVWAMFEWG----------------RRHLPGRHRLQLTHLGCGAEVG
: * . . .
Mb1754c|M.bovis_AF2122/97 VVEFRYHGERPLWAWLVLEPGDISVCLHDPCLPVDLTVRGHPRDLYRVYS
Rv1725c|M.tuberculosis_H37Rv VVEFRYHGERPLWAWLVLEPGDISVCLHDPCLPVDLTVRGHPRDLYRVYS
MSMEG_5032|M.smegmatis_MC2_155 VRMVTPEGQA---AVEINEHT---VESLDDEADVDVTLTGAAEVLAAAMD
TH_2405|M.thermoresistible__bu VRLVTPEGAA---AVRISADA---VEDLDDDTAVDVTLTGAAEVLAAALH
Mflv_2233|M.gilvum_PYR-GCK LSLVTPEGAV---TLAVDDRG---VHSVGEDRPVDVTLRGSGETLFAAMD
MMAR_1147|M.marinum_M TYRAEIDGRR---FEFVVERG----RLGPARGAPTVTISAAALDLVTARL
MUL_0912|M.ulcerans_Agy99 TYRAEIDGRR---FEFAVERG----RLGPARGAPTVTISVAALDLVTARL
Mvan_1032|M.vanbaalenii_PYR-1 VYEFHVDDST---ACLQIRDGRVSVRPGPCATPADVTVRATARAIAAVVG
MAB_3456|M.abscessus_ATCC_1997 VLHIQPTCES----------------CGEAVTFDDLTPRRLGRVR-----
MAV_4183|M.avium_104 VEIRCAEGHL--------------------VPPDELGMRLAKKSG-----
:
Mb1754c|M.bovis_AF2122/97 GRSTLAAEISAERIELDGLPAMRRAFPSWMAWSPFAPAMRQAVVSVDQMP
Rv1725c|M.tuberculosis_H37Rv GRSTLAAEISAERIELDGLPAMRRAFPSWMAWSPFAPAMRQAVVSVDQMP
MSMEG_5032|M.smegmatis_MC2_155 -PGQVENLVAAGLLTIDGDARAVRRLAKAFAPPRVRV-------------
TH_2405|M.thermoresistible__bu -PDRAAELVAQGRLRVDGRADALRRLAEVVTAPAGRAVPDRS--------
Mflv_2233|M.gilvum_PYR-GCK -PGRIADLVASGLLQVDGKRDAVRRVADLFA-------------------
MMAR_1147|M.marinum_M GADEATRKAALGRIDFDGDPGAIDALCTAFSLSGNSPRARGADGRS----
MUL_0912|M.ulcerans_Agy99 GADEATRKAALGRIDFDGDPGAIDALCTAFSLSGNSPRARGADGRS----
Mvan_1032|M.vanbaalenii_PYR-1 QKDRLEDAVAEGRIEVTGDPAAIATLIGAVEKRLA---------------
MAB_3456|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4183|M.avium_104 --------------------------------------------------
Mb1754c|M.bovis_AF2122/97 EAHGG
Rv1725c|M.tuberculosis_H37Rv EAHGG
MSMEG_5032|M.smegmatis_MC2_155 -----
TH_2405|M.thermoresistible__bu -----
Mflv_2233|M.gilvum_PYR-GCK -----
MMAR_1147|M.marinum_M -----
MUL_0912|M.ulcerans_Agy99 -----
Mvan_1032|M.vanbaalenii_PYR-1 -----
MAB_3456|M.abscessus_ATCC_1997 -----
MAV_4183|M.avium_104 -----