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STYSQFCPVAKAMELLDERWTLLVVRELLLGSTHFNDLRRGVPKMSPALLSKRLKSLTKAGVVERSDIEG RTSYSLTTCGRELATVVDALGEWGIRWIPELGDEDLDPHLLMWDIRRTVPIDAWPRARTVLAFRLAGVAP KAARWWLLVSEGEADVCDFDPGYQVAATVETSLLTLTQLWRGDQSWSRAMLNGGVRIDGPAQVRRSVPAW LGQSRLAAVPRPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1626 | - | - | 100% (224) | transcriptional regulator |
| M. marinum M | MMAR_1147 | - | 1e-14 | 36.11% (108) | transcriptional regulatory protein |
| M. marinum M | MMAR_1555 | - | 2e-11 | 39.36% (94) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1754c | - | 8e-34 | 36.04% (222) | hypothetical protein Mb1754c |
| M. gilvum PYR-GCK | Mflv_2233 | - | 8e-15 | 36.51% (126) | HxlR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1725c | - | 8e-34 | 36.04% (222) | hypothetical protein Rv1725c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3456 | - | 6e-12 | 36.84% (95) | HxlR family transcriptional regulator |
| M. avium 104 | MAV_4183 | - | 4e-08 | 32.65% (98) | putative transcriptional regulator family protein |
| M. smegmatis MC2 155 | MSMEG_5032 | - | 8e-14 | 30.05% (213) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_2405 | - | 5e-15 | 30.04% (223) | putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_3410 | - | 1e-129 | 99.55% (224) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1032 | - | 2e-13 | 38.38% (99) | HxlR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1626|M.marinum_M ------------MSTYSQFCPVAKAMELLDERWTLLVVRELLLGSTHFND
MUL_3410|M.ulcerans_Agy99 ------------MSTYSQFCPVAKAMELLDERWTLLVVRELLLGSTHFND
Mb1754c|M.bovis_AF2122/97 ------------MQPYGQYCPVARAAELLGDRWTLLIVRELLFGPLRFTE
Rv1725c|M.tuberculosis_H37Rv ------------MQPYGQYCPVARAAELLGDRWTLLIVRELLFGPLRFTE
MSMEG_5032|M.smegmatis_MC2_155 ----------MASRSYGQYCALAKSLDLVGDRWTLLVVRELLDGPRRYGD
TH_2405|M.thermoresistible__bu ----------MASRTYGQHCALAKSLDLVGDRWTLLIVRELLDGPRRYSD
Mflv_2233|M.gilvum_PYR-GCK ----------MPTRSYRQYCAVAKSLDLVGDRWTLLIVRELLDGPQRYGD
Mvan_1032|M.vanbaalenii_PYR-1 ----MSTIVGMTRRSYGQFCGLAHALDVVGERWTLLIVRELGSGPKRYGE
MAB_3456|M.abscessus_ATCC_1997 -----------MDFTTMRNCSISNALDVIGERWTLVALREIMLGNRRFET
MAV_4183|M.avium_104 MTLLQGPLADRDAWSAVGECAIEKTMAVVGTKSAMLIMREAYYGTTRFDD
. * : .: ::. : ::: :** * ::
MMAR_1626|M.marinum_M LRRGVPKMSPALLSKRLKSLTKAGVVERSD-----IEGRTSYSLTTCGRE
MUL_3410|M.ulcerans_Agy99 LRRGVPKMSPALLSKRLKSLTKAAVVERSD-----IEGRTSYSLTTCGRE
Mb1754c|M.bovis_AF2122/97 IERGLPGISRSVLAQRLRRLQHDRIIEAVP-----EHTGGGYRFTVAGEE
Rv1725c|M.tuberculosis_H37Rv IERGLPGISRSVLAQRLRRLQHDRIIEAVP-----EHTGGGYRFTVAGEE
MSMEG_5032|M.smegmatis_MC2_155 LLSALSPIATDVLAGRLRDLEANNLVHKRA--MPRPSATTVYALTADGRA
TH_2405|M.thermoresistible__bu LLTALRPIATDMLATRLRHLEEHHLVRRRE--LPKPASGTVYELTADGAA
Mflv_2233|M.gilvum_PYR-GCK LSAALSPIATDMLASRLRDMEAHGLLRKHR--MPKPASATVYEPTDEGRS
Mvan_1032|M.vanbaalenii_PYR-1 LADALAGIGTSLLATRMRQLETDGVIQRRLD-LDQPGSAVVYELSDAGRE
MAB_3456|M.abscessus_ATCC_1997 IVRNTG-ASRDILATRLRKLVDAGVLEKRR--YEDRPPRYEYLLTQSGQA
MAV_4183|M.avium_104 FARRVG-ITKAATSARLAELVELGLLKRRPYREPGQRSRDEYVLTQAGID
: : *: : ::. * : *
MMAR_1626|M.marinum_M LATVVDALGEWGIRWIP-ELGD--EDLDPHLLMWDIRRTVPIDAWPRART
MUL_3410|M.ulcerans_Agy99 LATVVDALGEWGIRWIP-ELGD--EDLDPHLLMWDIRRTVPIDAWPRART
Mb1754c|M.bovis_AF2122/97 LRPVLQTLGDWVSRWLMADPTP--AECDPELLTLWISRRVNTEALPGRRV
Rv1725c|M.tuberculosis_H37Rv LRPVLQTLGDWVSRWLMADPTP--AECDPELLTLWISRRVNTEALPGRRV
MSMEG_5032|M.smegmatis_MC2_155 LEDVINAFARWGRHLLANRDR--KETVRPEWLVRAVRAYVRDDR-TGPPV
TH_2405|M.thermoresistible__bu LEAVVHAFIRWGRSLLETRRA--GDVVRPHWLARAVRAHVRPDR-TGPPL
Mflv_2233|M.gilvum_PYR-GCK LEGVVDALARWGRRLVQTREP--GDVLQPQWLARAVRAYIRDDR-TGPPV
Mvan_1032|M.vanbaalenii_PYR-1 LAEAMIPLAMWGARHQMSHADPCAEAFRAEWLLAFLAADLRGGIPEGLAS
MAB_3456|M.abscessus_ATCC_1997 LRPVLFALMEWGDKFVTKGPPP----------------------------
MAV_4183|M.avium_104 FMPVVWAMFEWGRRHLPGRHR-----------------------------
: .: .: *
MMAR_1626|M.marinum_M VLAFRLAGVAPKAARWWLLVSEGEADVCDFDPGYQVAATVETSLLTLTQL
MUL_3410|M.ulcerans_Agy99 VLAFRLAGVAPKAARWWLLVSEGEADVCDFDPGYQVAATVETSLLTLTQL
Mb1754c|M.bovis_AF2122/97 VVEFRYHGERPLWA--WLVLEPGDISVCLHDPCLPVDLTVRGHPRDLYRV
Rv1725c|M.tuberculosis_H37Rv VVEFRYHGERPLWA--WLVLEPGDISVCLHDPCLPVDLTVRGHPRDLYRV
MSMEG_5032|M.smegmatis_MC2_155 TVRMVTPEGQ-----AAVEINEHTVESLDD--EADVDVTLTGAAEVLAAA
TH_2405|M.thermoresistible__bu SVRLVTPEGA-----AAVRISADAVEDLDD--DTAVDVTLTGAAEVLAAA
Mflv_2233|M.gilvum_PYR-GCK VLSLVTPEGA-----VTLAVDDRGVHSVGE--DRPVDVTLRGSGETLFAA
Mvan_1032|M.vanbaalenii_PYR-1 VYEFHVDDST-----ACLQIRDGRVSVRPGPCATPADVTVRATARAIAAV
MAB_3456|M.abscessus_ATCC_1997 -------------------------------------SIWEHQCGSVLHI
MAV_4183|M.avium_104 -------------------------------------LQLTHLGCGAEVG
MMAR_1626|M.marinum_M WRGDQSWSRAMLNGGVRIDGPAQVRRSVPAWLGQSRLAAVPRPA------
MUL_3410|M.ulcerans_Agy99 WRGDQSWSRAMLNGGVRIDGPAQVRRSVPAWLGQSRLAAVPRPA------
Mb1754c|M.bovis_AF2122/97 YSGRSTLAAEISAERIELDGLPAMRRAFPSWMAWSPFAPAMRQAVVSVDQ
Rv1725c|M.tuberculosis_H37Rv YSGRSTLAAEISAERIELDGLPAMRRAFPSWMAWSPFAPAMRQAVVSVDQ
MSMEG_5032|M.smegmatis_MC2_155 MDP-GQVENLVAAGLLTIDGDARAVRRLAKAFAPPRVRV-----------
TH_2405|M.thermoresistible__bu LHP-DRAAELVAQGRLRVDGRADALRRLAEVVTAPAGRAVPDRS------
Mflv_2233|M.gilvum_PYR-GCK MDP-GRIADLVASGLLQVDGKRDAVRRVADLFA-----------------
Mvan_1032|M.vanbaalenii_PYR-1 VGQKDRLEDAVAEGRIEVTGDPAAIATLIGAVEKRLA-------------
MAB_3456|M.abscessus_ATCC_1997 QPTCESCGEAVTFDDLTPRRLGRVR-------------------------
MAV_4183|M.avium_104 VEIRCAEGHLVPPDELGMRLAKKSG-------------------------
: :
MMAR_1626|M.marinum_M -------
MUL_3410|M.ulcerans_Agy99 -------
Mb1754c|M.bovis_AF2122/97 MPEAHGG
Rv1725c|M.tuberculosis_H37Rv MPEAHGG
MSMEG_5032|M.smegmatis_MC2_155 -------
TH_2405|M.thermoresistible__bu -------
Mflv_2233|M.gilvum_PYR-GCK -------
Mvan_1032|M.vanbaalenii_PYR-1 -------
MAB_3456|M.abscessus_ATCC_1997 -------
MAV_4183|M.avium_104 -------