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MRTRVAELLGAEFPICAFSHCRDVVAAVSNAGGFGILGAVAHSPKRLESELTWIEEHTGGKPYGVDVLLP PKYIGAEQGGIDAQQARELIPEGHRTFVDDLLVRYGIPAVTDRQRSSSAGGLHISPKGYQPLLDVAFAHD IRLIASALGPPPPDLVERAHNHDVLVAALAGTAQHARRHAAAGVDLIVAQGTEAGGHTGEVATMVLVPEV VDAVSPTPVLAAGGIARGRQIAAALALGAEGVWCGSVWLTTEEAETPPVVKDKFLAATSSDTVRSRSLTG KPARMLRTAWTDEWDRPDSPDPLGMPLQSALVSDPQLRINQAAGQPGAKARELATYFVGQVVGSLDRVRS ARSVVLDMVEEFIDTVGQLQGLVQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1560 | - | - | 100% (375) | hypothetical protein Mb1560 |
| M. bovis AF2122 / 97 | Mb1927c | - | 4e-91 | 47.61% (376) | hypothetical protein Mb1927c |
| M. bovis AF2122 / 97 | Mb3583 | - | 1e-29 | 31.97% (294) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0037 | - | 6e-96 | 50.00% (372) | 2-nitropropane dioxygenase, NPD |
| M. tuberculosis H37Rv | Rv1533 | - | 0.0 | 100.00% (375) | hypothetical protein Rv1533 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4162c | - | 1e-91 | 47.40% (384) | putative 2-nitropropane dioxygenase |
| M. marinum M | MMAR_2346 | - | 0.0 | 84.80% (375) | dioxygenase |
| M. avium 104 | MAV_3237 | - | 0.0 | 85.29% (374) | 2-nitropropane dioxygenase, NPD |
| M. smegmatis MC2 155 | MSMEG_0992 | - | 6e-98 | 50.53% (374) | 2-nitropropane dioxygenase, NPD |
| M. thermoresistible (build 8) | TH_4620 | - | 1e-102 | 50.40% (375) | PUTATIVE 2-nitropropane dioxygenase, NPD |
| M. ulcerans Agy99 | MUL_1143 | - | 1e-90 | 47.21% (377) | hypothetical protein MUL_1143 |
| M. vanbaalenii PYR-1 | Mvan_0883 | - | 1e-98 | 51.08% (372) | 2-nitropropane dioxygenase, NPD |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0037|M.gilvum_PYR-GCK MSMTSTALCEQFGIDFPLFAFSHCRDVVAAVTNAGGFGVLGATAYS-PDQ
Mvan_0883|M.vanbaalenii_PYR-1 --MTSTALCEQFGIDFPLFAFSHCRDVVAAVTNAGGFGVLGATAYT-PEQ
MSMEG_0992|M.smegmatis_MC2_155 ---MKPAICEQFGIDFPLFAFSHCRDVVAAVTNAGGFGVLGATAYT-PEQ
TH_4620|M.thermoresistible__bu ---MTSALCEQFGIDFPLFAFSHCRDVVAAVTNAGGFGVLGATAYT-PEQ
Mb1560|M.bovis_AF2122/97 ---MRTRVAELLGAEFPICAFSHCRDVVAAVSNAGGFGILGAVAHS-PKR
Rv1533|M.tuberculosis_H37Rv ---MRTRVAELLGAEFPICAFSHCRDVVAAVSNAGGFGILGAVAHS-PKR
MAV_3237|M.avium_104 ---MRTRVAELLGVEFPICAFSHCRDVVAAVTNAGGFGILGATAHS-PQR
MMAR_2346|M.marinum_M ---MRTRVAEMLGVEFPICAFSHCRDVVAAVTNAGGFGILGATAHS-PKR
MAB_4162c|M.abscessus_ATCC_199 ---MRTDLCERFGIRYPIFGFTPSEKVAAAISRAGGMGVLGCVRFNDPDE
MUL_1143|M.ulcerans_Agy99 ---MHTAICDELGIEFPIFAFTHCRDVVLAVSKAGGFGVLGAVGFT-PEQ
. :.: :* :*: .*: ...*. *::.***:*:**.. .. *..
Mflv_0037|M.gilvum_PYR-GCK LDQELAWIDEAVGGRPYGVDLIVPAKFE---GKGE-KLSSSDLAARIPQT
Mvan_0883|M.vanbaalenii_PYR-1 LDQELAWIDDAVGGKPYGVDLIVPAKFE---GKGE-KLSSSELAARIPQA
MSMEG_0992|M.smegmatis_MC2_155 LDQELSWIDEQVGGKPYGADIIVPAKFE---GKGE-NLTRDQLKDRIPGE
TH_4620|M.thermoresistible__bu LDRELSWIDEQVNGKPYGADIIVPAKFE---GKGEKDVTAQKLADRIPQQ
Mb1560|M.bovis_AF2122/97 LESELTWIEEHTGGKPYGVDVLLPPKYI---GAEQGGIDAQQARELIPEG
Rv1533|M.tuberculosis_H37Rv LESELTWIEEHTGGKPYGVDVLLPPKYI---GAEQGGIDAQQARELIPEG
MAV_3237|M.avium_104 LDNELNWIEQQTGGKPYGVDLLLPPKYV---GAEQGGIDAGQARTLLPDE
MMAR_2346|M.marinum_M LESELTWIEEQTRGKPYGVDLLLPPKYV---GAEQGGIDPVQARELVPEA
MAB_4162c|M.abscessus_ATCC_199 LDAVLNWMDENTDGKPYGVDIVMP-------AKVPAEGTAVDIDKLIPQG
MUL_1143|M.ulcerans_Agy99 LEIELNWIDEHIGDHPYGVDIVIPNKYEGMDSHLSAEELANTLRSMVPQQ
*: * *::: .:***.*:::* . :*
Mflv_0037|M.gilvum_PYR-GCK YKDLVDELLRKHDIE-------PEPERRIGKPMLSGNTGRELLDVALTHP
Mvan_0883|M.vanbaalenii_PYR-1 YRDLVDDLLRAHDIE-------PEPNRRLGGSSLSGNTGRELLDVALTHP
MSMEG_0992|M.smegmatis_MC2_155 YRDFITGLLAEHGIE-------PDPKQRLGGSSLSGDTGRELLDVALSHP
TH_4620|M.thermoresistible__bu YRDFINELLAAHDIE-------PEPKPKLGGTSLSGDTGKELLEVAMSHP
Mb1560|M.bovis_AF2122/97 HRTFVDDLLVRYGIP---AVTDRQRSSSAGGLHISPKGYQPLLDVAFAHD
Rv1533|M.tuberculosis_H37Rv HRTFVDDLLVRYGIP---AVTDRQRSSSAGGLHISPKGYQPLLDVAFAHD
MAV_3237|M.avium_104 HRAFVDDLLARYGVT---APAADIR---AGGLNISPKTYQPLLDVAFAHD
MMAR_2346|M.marinum_M HRAFVEELLARYGIAPSPEAGAERISRSGGGLNISPKGYEPLLDVAFSHD
MAB_4162c|M.abscessus_ATCC_199 HKDFVEKTLADLGVP-----PLPGERESAGVLGWLHSVARSHVEVALKHP
MUL_1143|M.ulcerans_Agy99 HLDFARKILADHGVP-----IEDADEDSLQLLGWTEATATPQVEVALKHS
: : * .: ::**: *
Mflv_0037|M.gilvum_PYR-GCK -VKLIANALGVPPDYMIEAGKERGIPVAALVGAKEHAVKQAAAGVDLIVA
Mvan_0883|M.vanbaalenii_PYR-1 -VKLIANALGVPPDYMIEAGKERGIPVAALVGAKEHAVKQAAAGVDLIVA
MSMEG_0992|M.smegmatis_MC2_155 -IKLIANALGVPPDYMIEAGRERGVPVAALVGAREHALKQVQAGVDLIVA
TH_4620|M.thermoresistible__bu -IKLIANALGVPPDYMLEAGREHGVPVAALVGAREHAVKQVRAGVDLIIA
Mb1560|M.bovis_AF2122/97 -IRLIASALGPPPPDLVERAHNHDVLVAALAGTAQHARRHAAAGVDLIVA
Rv1533|M.tuberculosis_H37Rv -IRLIASALGPPPPDLVERAHNHDVLVAALAGTAQHARRHAAAGVDLIVA
MAV_3237|M.avium_104 -IRLIASALGPPPPDLVERAHDRDVLVAALAGTTAHAQRHAAAGVDLIVA
MMAR_2346|M.marinum_M -IRLIASALGPPPSDLVERAHKKEVLVAALAGTTQHARRHAAAGVDLIVA
MAB_4162c|M.abscessus_ATCC_199 -IKLIANALGSPPKDVIDQAHEHGVPVAALAGKAEHARRHVENGVDIVVA
MUL_1143|M.ulcerans_Agy99 KVTMIANALGTPPAEMIAHIHERGRKVAALCGSPSQARKHANAGVDIIIA
: :**.*** ** :: :.: **** * :* ::. ***:::*
Mflv_0037|M.gilvum_PYR-GCK QGTEAGGHCGEVSTLVVVPEVLEGLAALGVSTPVLAAGGIVTGRQMAGMV
Mvan_0883|M.vanbaalenii_PYR-1 QGTEAGGHCGEVSTLVVVPEVLEALAGIGSSTPVLAAGGIVTGRQMAGMV
MSMEG_0992|M.smegmatis_MC2_155 QGTEAGGHCGEVSTLVLVPEVIDTLAQAGSDIPVLAAGGIVTGRQMAAAV
TH_4620|M.thermoresistible__bu QGTEAGGHTGEVTTMVLIPEVIEAIEAEGANVPVLAAGGIVTGRQMAAAV
Mb1560|M.bovis_AF2122/97 QGTEAGGHTGEVATMVLVPEVVDAVSPT----PVLAAGGIARGRQIAAAL
Rv1533|M.tuberculosis_H37Rv QGTEAGGHTGEVATMVLVPEVVDAVSPT----PVLAAGGIARGRQIAAAL
MAV_3237|M.avium_104 QGTEAGGHTGEVATMVLVPEVVDAVAPV----PVLAAGGIARGRQIAAAL
MMAR_2346|M.marinum_M QGTEAGGHTGEVATMVLVPEVVDAVAPT----PVLAAGGIARGRQIAAAL
MAB_4162c|M.abscessus_ATCC_199 QGYEAGGHTGDVASMVLWPEIVDALDGS---APVLAAGGIGSGRQAAAAL
MUL_1143|M.ulcerans_Agy99 QGGEAGGHCGEVGSIVLWPQVVKEVA-P---VPVLAAGGIGSGQQIAAAL
** ***** *:* ::*: *:::. : ******** *:* *. :
Mflv_0037|M.gilvum_PYR-GCK AMGASGAWTGSVWLTTEE-------AETAPHTVAKMLAATSRDTVRSAGR
Mvan_0883|M.vanbaalenii_PYR-1 AMGAAGAWTGSVWLTTEE-------AETAPHTVAKMLAATSRDTVRSAGR
MSMEG_0992|M.smegmatis_MC2_155 AMGAAGAWTGSVWLTTEE-------AETAPATVQKMLAATSRDTIRSTGR
TH_4620|M.thermoresistible__bu AMGAAGAWTGSVWLTTEE-------AETAPYTVQKLLAASSRDTIRSAGR
Mb1560|M.bovis_AF2122/97 ALGAEGVWCGSVWLTTEE-------AETPPVVKDKFLAATSSDTVRSRSL
Rv1533|M.tuberculosis_H37Rv ALGAEGVWCGSVWLTTEE-------AETPPVVKDKFLAATSSDTVRSRSL
MAV_3237|M.avium_104 ALGAEGVWCGSVWLTTEE-------AETVPVVKEKFLAATSSDTVRSRSM
MMAR_2346|M.marinum_M ALGAEGVWCGSVWLTTEE-------AETVPAVKDKFLAATSSDTVRSRSM
MAB_4162c|M.abscessus_ATCC_199 ALGASGVWTGSIWLTAAEYDLGTVTAGGDSVVQQALLKATSGDTVRTRIY
MUL_1143|M.ulcerans_Agy99 ALGCQGAWTGSQWLMVEE-------ASNTPVQQAAYAKASSRDTVRSRSF
*:*. *.* ** ** . * * . *:* **:*:
Mflv_0037|M.gilvum_PYR-GCK TGKPSRQLVSDWTKAWAPSKDGEQPLGLPLQSMLCEPVIRRIDVLASQGH
Mvan_0883|M.vanbaalenii_PYR-1 TGKPSRQLVSDWTNAWVPAKDGHQPLGLPLQSMLCEPVIRRIDVLASQGH
MSMEG_0992|M.smegmatis_MC2_155 TGKPARQLVSDWTKAWAPTPGGHPTLPLPLQNMLAEPVIRRIDVLAAQGH
TH_4620|M.thermoresistible__bu TGKPSRQLKSAWTEAWLPSDGGRQPLPLPLQSMISEPVLRRIDALAAQGH
Mb1560|M.bovis_AF2122/97 TGKPARMLRTAWTDEWD-RPDSPDPLGMPLQSALVSDPQLRINQAAGQPG
Rv1533|M.tuberculosis_H37Rv TGKPARMLRTAWTDEWD-RPDSPDPLGMPLQSALVSDPQLRINQAAGQPG
MAV_3237|M.avium_104 TGKPARMLRTAWTDEWD-RPENPDPLGMPLQTALITEPQLRINAAATQPG
MMAR_2346|M.marinum_M TGKPARMLRTAWTDEWA-RPDTPEPLGMPLQTTLITDSQIRINQAAVQPG
MAB_4162c|M.abscessus_ATCC_199 TGKPARLLKTKWTQAWD-AEDAPTPLPMPLQNILVSEAHERMNR-AHDPE
MUL_1143|M.ulcerans_Agy99 TGKPARMLRNDWTEAWE-QADNPKPLGMPLQYMVSGMAVRATNKYPNETV
****:* * . **. * .* :*** : : . :
Mflv_0037|M.gilvum_PYR-GCK EGAQALATYFVGQGVGLMNKVKPAREVVREFIEDYLAAAERLSSSLPG--
Mvan_0883|M.vanbaalenii_PYR-1 EGAQALATYFVGQGVGLMNKVKPAREVVREFIEDYLAAAERLSNSLPG--
MSMEG_0992|M.smegmatis_MC2_155 QGAQELATYFVGQGVGLMNKVKPAKEVVREFIEDYLAATERLSNSLPD--
TH_4620|M.thermoresistible__bu KGAQQLATYFVGQGVGLMNKVKPAREVVREFIEDYLAATERLSNSLPS--
Mb1560|M.bovis_AF2122/97 AKARELATYFVGQVVGSLDRVRSARSVVLDMVEEFIDTVGQLQGLVQR--
Rv1533|M.tuberculosis_H37Rv AKARELATYFVGQVVGSLDRVRSARSVVLDMVEEFIDTVGQLQGLVQR--
MAV_3237|M.avium_104 AKARELATYFVGQVVGSLDRIRPARAVVLDMVEEFIDTVGRLDGLIEN--
MMAR_2346|M.marinum_M AKARELATYFVGQVVGSLDRVRPTRSVVLEMVEEFIDTIGRLERLAD---
MAB_4162c|M.abscessus_ATCC_199 T----VCF-PAGQIVGRMNEIRPTAEIVADLVSGFEAAVDRLDEIRG---
MUL_1143|M.ulcerans_Agy99 D----VAFNPVGQVVGQFTKVEKAATVIERWVQEYLEATNRLDELNAAAV
:. .** ** : .:. : :: :. : : :*.