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MTVPPAGPYGNYPYGPNTYGQDLYWGGQPQGGSYPPAYPPQQYPPGWPAGPYPPGPPPPGPGSKTPWLIL AGLAVLGVILLVVILVIGLRGDNKSTTATSPATSAPTSQPFSQQTATGCTPNVSGGVQPIGDSISAGKLS FPTSAAPGWSAFSDDQNPNLIDAVGVGHEVAGADQWMMQAEVAITNFVTTMDVAAQASKLMQCVADGPGY AGSSPTLGPTKTSSITVDGVRAARVDADITIADSSRNVKGDSVTIIAVDTKPVTVFLGATPIGDATSRAT VERVIEALKVNKS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1127c | - | - | 100% (293) | hypothetical protein Mb1127c |
| M. bovis AF2122 / 97 | Mb2535 | - | 9e-12 | 29.41% (255) | proline rich membrane protein |
| M. bovis AF2122 / 97 | Mb0322c | - | 5e-08 | 34.26% (108) | hypothetical protein Mb0322c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2547 | - | 2e-11 | 29.12% (261) | hypothetical protein Mflv_2547 |
| M. tuberculosis H37Rv | Rv1097c | - | 1e-172 | 99.66% (293) | hypothetical protein Rv1097c |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 1e-06 | 38.14% (97) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_2112 | - | 1e-07 | 30.23% (129) | hypothetical protein MAB_2112 |
| M. marinum M | MMAR_4369 | - | 1e-115 | 66.67% (327) | membrane glycine and proline rich protein |
| M. avium 104 | MAV_1219 | - | 1e-99 | 57.52% (339) | hypothetical protein MAV_1219 |
| M. smegmatis MC2 155 | MSMEG_4720 | - | 8e-12 | 29.88% (251) | hypothetical protein MSMEG_4720 |
| M. thermoresistible (build 8) | TH_1385 | - | 4e-11 | 28.81% (236) | POSSIBLE CONSERVED PROLINE RICH MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_0182 | - | 1e-115 | 66.97% (327) | membrane glycine and proline rich protein |
| M. vanbaalenii PYR-1 | Mvan_4096 | - | 6e-12 | 32.68% (257) | hypothetical protein Mvan_4096 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2547|M.gilvum_PYR-GCK MGMKDSPGHGRNE---WGERDS----------------------GYSGYS
Mvan_4096|M.vanbaalenii_PYR-1 MGMTDSPSRGREERSGLGGREEQSGLGGREEQSGLGGRGEQSGWGYPGYS
MSMEG_4720|M.smegmatis_MC2_155 MGMTDSPRRDGNEPTQQFGSGY-----------------------PVEYP
TH_1385|M.thermoresistible__bu --MTESPRRGGTDPTEPMYPG---------------------------YS
Mb1127c|M.bovis_AF2122/97 --MTVPP--AGPYGNYPYGPNT--------------------------YG
Rv1097c|M.tuberculosis_H37Rv --MTVPP--AGPYGNYPYGPNT--------------------------YG
MMAR_4369|M.marinum_M --MTTPP--GGPYGQDPAGYNP--------------------------YG
MUL_0182|M.ulcerans_Agy99 --MTTPP--GGPYGQDPAGYNP--------------------------YG
MAV_1219|M.avium_104 --MTAPP--GGPYGPGSYGSNP--------------------------YG
MAB_2112|M.abscessus_ATCC_1997 --MTGPNDPYQYGGTGQWGAPE-----------------------GQWQG
MLBr_02395|M.leprae_Br4923 --MTDQPPPSGSNPTPAPPPPG------------------------SSGG
*.
Mflv_2547|M.gilvum_PYR-GCK DPAYASQTPYGPPYQ--------------PTERLPAYPPYGYNPT-----
Mvan_4096|M.vanbaalenii_PYR-1 DPAYASQTPYAPPYQAPP--------GPRPTERLPAYSPYGQ--------
MSMEG_4720|M.smegmatis_MC2_155 DPAYANQTPYGGGYPAAPNPVSNPPANPQPTQQMPAYPPYGY--------
TH_1385|M.thermoresistible__bu DPAYASQA-YGPTYPASP--------QPPPTEQLPAYPPYGY--------
Mb1127c|M.bovis_AF2122/97 QDLYWGGQPQGG-----------------------SYPP-----------
Rv1097c|M.tuberculosis_H37Rv QDPYWGGQPQGG-----------------------SYPP-----------
MMAR_4369|M.marinum_M QAPYGYGQPQAGGQY--------------------PYPPTGPYTN-----
MUL_0182|M.ulcerans_Agy99 QAPYGYGQPQAGGQY--------------------PYPPTGPYTN-----
MAV_1219|M.avium_104 QEPNWSGQPPGGQPQGGQ-------------PQGGPYPQPGQYPAGGPYP
MAB_2112|M.abscessus_ATCC_1997 APPAQGQYGYAQEYFG---------------QAPADYPDDSIG-------
MLBr_02395|M.leprae_Br4923 YEPSFAPSELGSAYPP------------------PTAPPVGGSYP-----
. .
Mflv_2547|M.gilvum_PYR-GCK -----------ADPNATGQYPP--------QYPPHGPG--PEPPQDPKSP
Mvan_4096|M.vanbaalenii_PYR-1 ------------DPYATGQYPP--------QYPPQGYGSEPPPPEDPKSP
MSMEG_4720|M.smegmatis_MC2_155 ------------DPYASGQYGSGQYG----GFPPAGPPP-EPEPEDREPR
TH_1385|M.thermoresistible__bu ------------DPYGTGQQG---Y-----EYPPAEPP----EPEKPKLP
Mb1127c|M.bovis_AF2122/97 -------------AYPPQQYP---------PGWPAGPYPPGPPPPGPGSK
Rv1097c|M.tuberculosis_H37Rv -------------AYPPQQYP---------PGWPAGPYPPGPPPPGPGSK
MMAR_4369|M.marinum_M --PQGGAPSYGPGTYPPQQFPQAGQPYGTGPGWPTGPYSPGPPPKGPGSK
MUL_0182|M.ulcerans_Agy99 --PQGGAPSYGPGTYPPQQFPQAGQPYGTGPGWPTGPYSPGPPPKGPGSK
MAV_1219|M.avium_104 YPPPGGGYPYPGGPYPGGPYPGAPYPGPGQPFGPGGPYSPGPPPGGPGSK
MAB_2112|M.abscessus_ATCC_1997 ------------RLYDGVPQG--------YAVPPMYPGLPGQDPFGPQKK
MLBr_02395|M.leprae_Br4923 -----------PPPPPGGSYPP--------PPPPGGSYPPPPPSTGAYAP
* .
Mflv_2547|M.gilvum_PYR-GCK -RWLWIVAGVAVVMVIGLVIALVIVNSSR---QE-TVVAPLPAAPEPSMT
Mvan_4096|M.vanbaalenii_PYR-1 -RWLWIVAGLAVLTVIGLVIALVIVNSSR---QQPVAITPLPSAPEPSYP
MSMEG_4720|M.smegmatis_MC2_155 -MWLWVLAALAVLVVVGLVIALVIANGSR---QE-TVVAP-PVSPQPSF-
TH_1385|M.thermoresistible__bu -GWLWVLAALAVLLVVGLVIALVITNSSQ---QD-TVFAPGPSATEPSFP
Mb1127c|M.bovis_AF2122/97 -TPWLILAGLAVLGVILLVVILVIGLRGD--NKSTTATSPATS-APTSQP
Rv1097c|M.tuberculosis_H37Rv -TPWLILAGLAVLGVILLVVILVIGLRGD--NKSTTATSPATS-APTSQP
MMAR_4369|M.marinum_M -APWLIIAGVAVLGVLALVVVLVFTLGGNKSNNAGPSGTPATSGDSTSEP
MUL_0182|M.ulcerans_Agy99 -APWLIIAGVAVLGVLALVVVLVFTLGGNKSNNAGPSGTPATSGASTSEP
MAV_1219|M.avium_104 -LPWLIVAGLVVLAVIALVATLVVMKGGH--GSKPSGATPSSTSTSVSQP
MAB_2112|M.abscessus_ATCC_1997 SKPWLLIASVAGAVVVVLALVLVLILNRD---SDPRQAASSPTTTTVSYA
MLBr_02395|M.leprae_Br4923 PPPGPAIRSLPKEAYTFWVTRVLAYVIDN---------IPATVLLGIGML
: .: . :: . . .
Mflv_2547|M.gilvum_PYR-GCK TSSPRSPTTTSRAPRTTTRPTTPLLPLPTLPS---TTP---DPTTPGATD
Mvan_4096|M.vanbaalenii_PYR-1 TP---APTTTSRPP---TRPSTPVLPAPTLPSAPRTTPP-TEPTVPGATD
MSMEG_4720|M.smegmatis_MC2_155 ----SEPTTTAPSP----SRTPRPVPVP-----PRTSAP-TSPTTPGATE
TH_1385|M.thermoresistible__bu MP--TPPTTTRRAP----TTVLPPLPSPGPTTGPTTGPP-GATTTPGATE
Mb1127c|M.bovis_AF2122/97 -FSQQTATGCTPNVSGGVQPIGDSISAGKLSFPTSAAP--GWSAFSDDQN
Rv1097c|M.tuberculosis_H37Rv -FSQQTATGCTPNVSGGVQPIGDSISAGKLSFPTSAAP--GWSAFSDDQN
MMAR_4369|M.marinum_M DNSEQNATGCTPNVSAGERPLGEIISAGKLSFPISAAP--GWSVFGDDQS
MUL_0182|M.ulcerans_Agy99 DNSEQNATGCTPNVSAGERPLGEIISAGKLSFPISAAP--GWSVFGDDQS
MAV_1219|M.avium_104 KNSAQNATDCTPNVSGGDMPRSDSIAAGKLSFPANAAPS-GWTVFSDDQG
MAB_2112|M.abscessus_ATCC_1997 NPELPTAGGAPTYHPPTAQPPTAQIPPPAPPQMPVPPPAPTGPPRAPGQV
MLBr_02395|M.leprae_Br4923 IQTLTKQEACVTDITQYNVNQYCATQPTGIGMLAFWFAWLMATAYLVWNY
. .
Mflv_2547|M.gilvum_PYR-GCK SVIYTVEGLGRAIN--LTYVDTGGLLQTEFNVMLPWTKEVALPRPGESSA
Mvan_4096|M.vanbaalenii_PYR-1 AVVYTVDGNGRAIN--ITYVDTGGLLQTEFNVMLPWSKEVSLPAPGEGSA
MSMEG_4720|M.smegmatis_MC2_155 TVVYEVAGEGRAIN--ITYLDTGGMLQTEFNVLLPWSKQVELPEPAKETA
TH_1385|M.thermoresistible__bu TVVYEVAGTGRAIN--ITYIDTGKVLQTEFNVQLPWRKQVELPSPAASSA
Mb1127c|M.bovis_AF2122/97 PNLIDAVGVGHEVAGADQWMMQAEVAITNFVTTMDVAAQASKLMQCVADG
Rv1097c|M.tuberculosis_H37Rv PNLIDAVGVGHEVAGADQWMMQAEVAITNFVTTMDVAAQASKLMQCVADG
MMAR_4369|M.marinum_M PNLIGALGVGQEVPDASQWMMQAEVAVTNFVASMDVSEQASKLMQCVVDG
MUL_0182|M.ulcerans_Agy99 PNLIGALGVGQEVPDASQWMMQAEVAVTNFVASMDVSEQASKLMQCVVDG
MAV_1219|M.avium_104 PNLIGALGVAQDVPGANQWMMTAEVGVTNFVPSMDLTAQATKLMQCLANG
MAB_2112|M.abscessus_ATCC_1997 ASVGDCIALAAPSDYKTVACTDPTAAWRVIEVVPGGKCRQTYTGFTAGDF
MLBr_02395|M.leprae_Br4923 GYRQGATG------------SSIGKTVMKFKVISEATGQPIGFGMS----
. : .
Mflv_2547|M.gilvum_PYR-GCK S---ITIINVGREVTCSITVNGTQRESRTGAGLTICAPTR----------
Mvan_4096|M.vanbaalenii_PYR-1 S---ISIINVGREVTCSITVNGVQLDERTGAGLTICTSTG----------
MSMEG_4720|M.smegmatis_MC2_155 S---VSVLNFGPEVSCTVTVDGVQTQHRTGSGLTICVGTMR---------
TH_1385|M.thermoresistible__bu S---VSIINVGRDVTCTVTVDGALIQQRTGSGLTICVGAG----------
Mb1127c|M.bovis_AF2122/97 PGYAGSSPTLGPTKTSSITVDGVR-AARVDADITIADSSRNVKGDSVTII
Rv1097c|M.tuberculosis_H37Rv PGYAGSSPTLGPTKTSSITVDGVR-AARVDADITIADSSRNVKGDSVTII
MMAR_4369|M.marinum_M PGYVQSSPTLGPTKKSSTTVDGVK-AARVDADITIADTSRNVKGDSVVII
MUL_0182|M.ulcerans_Agy99 PGYVQSSPTLGPTKKSSTTVDGVK-AARVDADITIADTSRNVKGDSVVII
MAV_1219|M.avium_104 PGYANAMPTLGPIKTSPITVDGTK-AVRADADVTIADPTRNVKGDSVTII
MAB_2112|M.abscessus_ATCC_1997 SYCIAPQLRVGSCYQTAVVMGSTVFVAADSCQAPKAFVVLFVIPGTKEAS
MLBr_02395|M.leprae_Br4923 -----VVRQLAHFVDAVICCIGFLFPLWDSKRQTLADKIMTTVCLPI---
.. . . . .
Mflv_2547|M.gilvum_PYR-GCK -------------------------------------
Mvan_4096|M.vanbaalenii_PYR-1 -------------------------------------
MSMEG_4720|M.smegmatis_MC2_155 -------------------------------------
TH_1385|M.thermoresistible__bu -------------------------------------
Mb1127c|M.bovis_AF2122/97 AVDTKPVTVFLGATPIGDATSRATVERVIEALKVNKS
Rv1097c|M.tuberculosis_H37Rv AVDTKPVTVFLGATPIGDATSRATVERVIEALKVNKS
MMAR_4369|M.marinum_M AVDTKPVTIFLGATPIGDAASAATISKVIAALKVDKS
MUL_0182|M.ulcerans_Agy99 AVDTKPVTIFLGATPIGDAASAATISKVIAALKVDKS
MAV_1219|M.avium_104 AVDTKPVSVFIGSTPIGDSASAGLIGKIIAALKVAKS
MAB_2112|M.abscessus_ATCC_1997 QCKGKPGVVHSFAFPDPPMAICTGEFAP---------
MLBr_02395|M.leprae_Br4923 -------------------------------------