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GMKDSPGHGRNEWGERDSGYSGYSDPAYASQTPYGPPYQPTERLPAYPPYGYNPTADPNATGQYPPQYPP HGPGPEPPQDPKSPRWLWIVAGVAVVMVIGLVIALVIVNSSRQETVVAPLPAAPEPSMTTSSPRSPTTTS RAPRTTTRPTTPLLPLPTLPSTTPDPTTPGATDSVIYTVEGLGRAINLTYVDTGGLLQTEFNVMLPWTKE VALPRPGESSASITIINVGREVTCSITVNGTQRESRTGAGLTICAPTR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2547 | - | - | 100% (259) | hypothetical protein Mflv_2547 |
| M. gilvum PYR-GCK | Mflv_4674 | - | 2e-17 | 32.75% (171) | hypothetical protein Mflv_4674 |
| M. gilvum PYR-GCK | Mflv_2951 | - | 1e-16 | 26.95% (282) | hypothetical protein Mflv_2951 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2535 | - | 2e-56 | 47.39% (249) | proline rich membrane protein |
| M. tuberculosis H37Rv | Rv2507 | - | 2e-56 | 47.39% (249) | proline rich membrane protein |
| M. leprae Br4923 | MLBr_00431 | - | 5e-51 | 43.03% (251) | hypothetical protein MLBr_00431 |
| M. abscessus ATCC 19977 | MAB_1539c | - | 6e-35 | 34.30% (242) | hypothetical protein MAB_1539c |
| M. marinum M | MMAR_3854 | - | 2e-58 | 50.83% (242) | proline rich membrane protein |
| M. avium 104 | MAV_1668 | - | 1e-58 | 49.79% (243) | hypothetical protein MAV_1668 |
| M. smegmatis MC2 155 | MSMEG_4720 | - | 2e-74 | 52.54% (276) | hypothetical protein MSMEG_4720 |
| M. thermoresistible (build 8) | TH_1385 | - | 9e-74 | 57.63% (262) | POSSIBLE CONSERVED PROLINE RICH MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3786 | - | 4e-57 | 50.00% (242) | proline rich membrane protein |
| M. vanbaalenii PYR-1 | Mvan_4096 | - | 1e-100 | 66.33% (297) | hypothetical protein Mvan_4096 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2547|M.gilvum_PYR-GCK MGMKDSPGHGRNE---WGERDS----------------------GYSGYS
Mvan_4096|M.vanbaalenii_PYR-1 MGMTDSPSRGREERSGLGGREEQSGLGGREEQSGLGGRGEQSGWGYPGYS
MSMEG_4720|M.smegmatis_MC2_155 MGMTDSPRRDGNEPTQQFGSGY-----------------------PVEYP
TH_1385|M.thermoresistible__bu --MTESPRRGGTDPTEPMYPG---------------------------YS
Mb2535|M.bovis_AF2122/97 --MNDPRRPQRFGPPLSGYGPTGP-----------------QVPPNPPTA
Rv2507|M.tuberculosis_H37Rv --MNDPRRPQRFGPPLSGYGPTGP-----------------QVPPNPPTA
MMAR_3854|M.marinum_M --MNDPRRPLRYGPPQPGPGPGWP-----------------QGPVNTPPA
MUL_3786|M.ulcerans_Agy99 --MNDPRRPLRYGPPQPGPGPGWP-----------------QGPVNTPPA
MLBr_00431|M.leprae_Br4923 --MNNPRRSEWLGPSLAGSGPIEP-----------------QVHQYPPLT
MAV_1668|M.avium_104 MDMNDSRPTERFSPPQ---------------------------PRYSPSV
MAB_1539c|M.abscessus_ATCC_199 --MDSNRRDDAAAPGGSTSYGSWP----------------QSSQPLDYPE
* .
Mflv_2547|M.gilvum_PYR-GCK DPAYASQTPYGPPYQ---------------------------PTERLP-A
Mvan_4096|M.vanbaalenii_PYR-1 DPAYASQTPYAPPYQAPP---------------------GPRPTERLP-A
MSMEG_4720|M.smegmatis_MC2_155 DPAYANQTPYGGGYPAAPNPVSNPP-------------ANPQPTQQMP-A
TH_1385|M.thermoresistible__bu DPAYASQA-YGPTYPASP---------------------QPPPTEQLP-A
Mb2535|M.bovis_AF2122/97 DPAYADQSPYASTYGGYVSPPWSPGGPPPRPPQWPPGPHEASPTQQLP-Q
Rv2507|M.tuberculosis_H37Rv DPAYADQSPYASTYGGYVSPPWSPGGPPPRPPQWPPGPHEASPTQQLP-Q
MMAR_3854|M.marinum_M DPAYADQAPYAPTYGGHV-PQWAPG-----------SYDEANPTQQLPPQ
MUL_3786|M.ulcerans_Agy99 DPAYADQAPYAPTYGGHV-PQWARG-----------SYDEANPTQQLPPQ
MLBr_00431|M.leprae_Br4923 DPAYAEQAPYAPAYGASL-PPWTPK----------------KPPQQLP-R
MAV_1668|M.avium_104 DPAYADQTPYAPTYGPTM-SPWAPA------------ANETNPTKQLP-A
MAB_1539c|M.abscessus_ATCC_199 DPAYASQAFEYPALSGTA---------------------QPNQTAVLPQQ
*****.*: . :*
Mflv_2547|M.gilvum_PYR-GCK YPPYGYNPTADPNATGQYPP----QYPPHGPG--PEPPQDPKSPRW-LWI
Mvan_4096|M.vanbaalenii_PYR-1 YSPYGQ----DPYATGQYPP----QYPPQGYGSEPPPPEDPKSPRW-LWI
MSMEG_4720|M.smegmatis_MC2_155 YPPYGY----DPYASGQYGSGQYGGFPPAGPPP-EPEPEDREPRMW-LWV
TH_1385|M.thermoresistible__bu YPPYGY----DPYGTGQQG---Y-EYPPAEPP----EPEKPKLPGW-LWV
Mb2535|M.bovis_AF2122/97 YWQYDQ-----PPPG---------GFPPDGLT--PPPPQGPRTPRW-LWF
Rv2507|M.tuberculosis_H37Rv YWQYDQ-----PPPG---------GFPPDGLT--PPPPQGPRTPRW-LWF
MMAR_3854|M.marinum_M YWQQNP-----GQPG---------EVLRDG----PPPPEGPKTPRW-LWI
MUL_3786|M.ulcerans_Agy99 YWQQNP-----GQPG---------EVLRDG----PPPPEGPKTPRW-LWI
MLBr_00431|M.leprae_Br4923 YWQQDQ-----PPPT---------DIPPEGLT--LPPPHEPKSPHWFLWV
MAV_1668|M.avium_104 YWQQEL-----PPGG---------DPHTPG-M--APPPGEPKSPRW-LWI
MAB_1539c|M.abscessus_ATCC_199 YGQQYG------------------SYGPAPKD---PEPPRRSNTFW-LWV
* * * **.
Mflv_2547|M.gilvum_PYR-GCK VAGVAVVMVIGLVIALVIVNSSRQE-TVVAPLPAAPEPSMTTSSPRSPTT
Mvan_4096|M.vanbaalenii_PYR-1 VAGLAVLTVIGLVIALVIVNSSRQQPVAITPLPSAPEPSYPTP---APTT
MSMEG_4720|M.smegmatis_MC2_155 LAALAVLVVVGLVIALVIANGSRQE-TVVAP-PVSPQPSF-----SEPTT
TH_1385|M.thermoresistible__bu LAALAVLLVVGLVIALVITNSSQQD-TVFAPGPSATEPSFPMP--TPPTT
Mb2535|M.bovis_AF2122/97 AAGSAVLLVVALVIALVIANGSVKKQTAIEPLPPMPGPSPTRP----TTT
Rv2507|M.tuberculosis_H37Rv AAGSAVLLVVALVIALVIANGSVKKQTAIEPLPPMPGPSPTRP----TTT
MMAR_3854|M.marinum_M AAGAAVVLVIGLVIALVIANISVKNQTALEPLPPIAGPSSTIA----PPT
MUL_3786|M.ulcerans_Agy99 AAGAAVVLVIGLVIALVIANISVKNQTALEPLPPIAGPSSTIA----PPT
MLBr_00431|M.leprae_Br4923 VAGASVVLVVGLVMALIIANGAIKTQTAVPPLPAITESSSATP----TPT
MAV_1668|M.avium_104 AAGAAVLLVVALVIALVLANDAIKTQTAVPPLPAMPEPSPETP----TTS
MAB_1539c|M.abscessus_ATCC_199 VGIGALVVIIALIITLVLLIQREDQ----QPPTVVSSPTTRTS----TTT
. ::: ::.*:::*:: . * . . .: ..:
Mflv_2547|M.gilvum_PYR-GCK TSRAPRTTTRPTTPLLPLPTLPS---TTP--DPTTPGATDSVIYTVEGLG
Mvan_4096|M.vanbaalenii_PYR-1 TSRPP---TRPSTPVLPAPTLPSAPRTTPPTEPTVPGATDAVVYTVDGNG
MSMEG_4720|M.smegmatis_MC2_155 TAPSP----SRTPRPVPVP-----PRTSAPTSPTTPGATETVVYEVAGEG
TH_1385|M.thermoresistible__bu TRRAP----TTVLPPLPSPGPTTGPTTGPPGATTTPGATETVVYEVAGTG
Mb2535|M.bovis_AF2122/97 TPTPP--------SPSAAPAPTTTTG--TPSET-VAGAMQTVVYDVTGEG
Rv2507|M.tuberculosis_H37Rv TPTPP--------SPSAAPAPTTTTG--TPSET-VAGAMQTVVYDVTGEG
MMAR_3854|M.marinum_M TRTSP--------TPSSSPAPTTTSGSATPTTTPTAGAMQTVVYTVTGEG
MUL_3786|M.ulcerans_Agy99 TRTSP--------TPSSSPAPTTTSGSATPTTTPTAGAMQTVVYTVTGEG
MLBr_00431|M.leprae_Br4923 TKTSP--------TPTAGPAPSTTGSG-TLTQTIGPSAMLDVVYSITGQG
MAV_1668|M.avium_104 THRSP--------SLIPAPIPPTSEPE-PPTATTGPAAMQDVVYTVSGEG
MAB_1539c|M.abscessus_ATCC_199 APSQP--------TIPPIPSFTIPPIPVNPPTQGSQAATESVVYEVGGRG
: * . * .* *:* : * *
Mflv_2547|M.gilvum_PYR-GCK RAINLTYVDTGGLLQTEFNVMLPWTKEVALPRPGESSASITIINVGREVT
Mvan_4096|M.vanbaalenii_PYR-1 RAINITYVDTGGLLQTEFNVMLPWSKEVSLPAPGEGSASISIINVGREVT
MSMEG_4720|M.smegmatis_MC2_155 RAINITYLDTGGMLQTEFNVLLPWSKQVELPEPAKETASVSVLNFGPEVS
TH_1385|M.thermoresistible__bu RAINITYIDTGKVLQTEFNVQLPWRKQVELPSPAASSASVSIINVGRDVT
Mb2535|M.bovis_AF2122/97 RAISITYMDSGNVIQTEFNVALPWRKEVSLSKSSLHPASVTIVNIGHNVT
Rv2507|M.tuberculosis_H37Rv RAISITYMDSGNVIQTEFNVALPWRKEVSLSKSSLHPASVTIVNIGHNVT
MMAR_3854|M.marinum_M RAISVTYMDTGDVIQTEFNVALPWSKEVSLSRSANHPASVTIVNIGHNVT
MUL_3786|M.ulcerans_Agy99 RAISVTYMDTGDVIQTEFNVALPWNREVSLSRSANHPASVTIVNIGHNVT
MLBr_00431|M.leprae_Br4923 RAISVTYMDTGDVIQTEFNVVLPWSKQVSLSKSAVHPASVTIVNIGHDVT
MAV_1668|M.avium_104 RAISIMYIDTGDLIQTEFNVALPWTKQVSLSKSAVHPANVTIVNIGHSVT
MAB_1539c|M.abscessus_ATCC_199 PALNVTYFDASGSLQMEFNVKLPWRKEVKLNTEQVTNAVVIAADFSHDVS
*:.: *.*:. :* **** *** ::* * * : :.. .*:
Mflv_2547|M.gilvum_PYR-GCK CSITVNGTQRESRTGAGLTICAPTR-
Mvan_4096|M.vanbaalenii_PYR-1 CSITVNGVQLDERTGAGLTICTSTG-
MSMEG_4720|M.smegmatis_MC2_155 CTVTVDGVQTQHRTGSGLTICVGTMR
TH_1385|M.thermoresistible__bu CTVTVDGALIQQRTGSGLTICVGAG-
Mb2535|M.bovis_AF2122/97 CSVTVAGVQVRQRTGAGLTICDAPS-
Rv2507|M.tuberculosis_H37Rv CSVTVAGVQVRQRTGAGLTICDAPS-
MMAR_3854|M.marinum_M CSVTVSGVQVRQRTGVGLTICDASG-
MUL_3786|M.ulcerans_Agy99 CSVTVSGVQVRQRTGVGLTICDASG-
MLBr_00431|M.leprae_Br4923 CSVTVAGVQIRQHTGVGLTICDAPR-
MAV_1668|M.avium_104 CTVTVNGVQVSRRVGGGLTICDARG-
MAB_1539c|M.abscessus_ATCC_199 CTLLVNGAQKSATSGK-MATCSTLG-
*:: * *. * :: *