For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. bovis AF2122 / 97 Mb0954c (pknDb)

annotation: serine/threonine protein kinase D
coordinates: 1038385 - 1039494
length: 369

LLATPADTGLSQSESGIAGAGTGPPTPGAARWSPGDSATVAGPLAADSRGGNWPSQTGHSPAVPNALQAS
LGHAVPPAGNKRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTGIDFRLSPSGVAVDS
AGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLAVDGAGTVYVTDFNNRVVTLAAGSNNQTVLP
FDGLNYPEGLAVDTQGAVYVADRGNNRVVKLAAGSKTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRV
VKLEAESNNQVVLPFTDITAPWGIAVDEAGTVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDS
DRTVYVADRGNDRVVKLTS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0954cpknDb-100% (369)serine/threonine protein kinase D
M. bovis AF2122 / 97Mb3554-5e-5645.61% (296) hypothetical protein Mb3554
M. bovis AF2122 / 97Mb1003cPE_PGRS174e-1233.17% (205) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1786-6e-0825.68% (183) SMP-30/gluconolaconase/LRE domain-containing protein
M. tuberculosis H37RvRv0931cpknD0.0100.00% (369) transmembrane serine/threonine-protein kinase D PKND
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2106c-1e-0725.53% (380) lipoprotein LppL
M. marinum MMMAR_4577pknD1e-11757.39% (399) transmembrane serine/threonine-protein kinase D PknD
M. avium 104MAV_4238-1e-12466.02% (362) serine/threonine-protein kinase PknD
M. smegmatis MC2 155MSMEG_5629-4e-1026.52% (230) hypothetical protein MSMEG_5629
M. thermoresistible (build 8)TH_0100-5e-1328.24% (255) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_4817-2e-1328.19% (259) hypothetical protein MUL_4817
M. vanbaalenii PYR-1Mvan_1720-3e-1427.31% (249) YVTN beta-propeller repeat-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       MGSRSAAHGGRSWRSGRHRKQRRIEPYAWLGAGAVTLGIGAAALSGAGIA
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       AADDPSTDSTSTSSSTEDNTSSDPRTPSSTRSTDAEEPSNDKNIEPPGND
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      -----------------------------------------VTVIGAQQV
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       SDDEADHEVDTTTETDAAARDGADGVDEEPRRNKGREDGIETYDPSPSVD
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      VDIALAEAARRGKADETMVLVTDRADASLRWAGNSMTTNGESVSRTTTVV
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       KQDNDTEANELTAVVDEDDAPRPRGAESQQRPAVGAVSPALTNTQSAPVP
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      SVVRRENSTHVASVRSSEVDPAAIPALVAASQDAALTAPEARDSAPPLPG
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       LAPHETTTTQLSPETPENATTTRLLDAPTEPFDSPLAWLLLASSRRQIGR
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      DTTPDDWDDPVPGTGVGEFTAIADGLVRGFRGADRLYGYARHIVETTFLA
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       VADEDAHSPAADALAVDAENTAPTAALRGQSSPGWFTGRVTGRVAASDVD
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      TSNGLRRRYTQPTGSVEINAKRDGASAWVGLNAPDFTAVTVDSMLEELST
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       GDRLSFTGMTTAKGTVTVTPWGTFTYRPSKAARHAAAATTASDAEKFDTF
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      RLGWARRRVELPAGRYETIMPPSTVADMLIYLNWHMDGRGAQEGRTALSA
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       AITVSDGNGGWTEVPVTVAVRPVNSSPSWLRSTKTKPNPVSGEVNGRIIA
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      PGGGTRVGEKLTDLPLTMYSDPTADGLECLPFVAVPASSDRVSVFDNGLA
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       IDRDGDAFTYTASAPGKGAVVVNLDGTFSYTASDSARAAARNTWYTDTDR
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      IGRVDWIRDGVINALAYPRAAAEEFHAPVAVPADNLLMTGGTASVRDMVA
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------MSDAVP
MMAR_4577|M.marinum_M               --------------------------------------------MSETGP
MAV_4238|M.avium_104                --------------------------------------------MSDNGP
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       FIVVVNDGHGGTRSVSVRVEVAPSNNAPTTGAPNLDAPDPGTGAVRGTVN
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      RTERGLLLTTFWYIRTVDPTTLLVTGLTRDGVYLVEDGEVTAAVNNFRFN
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --QVGSQFGPYQLLRLLGRGGMGEVYEAEDTRKHRVVALKLISPQYSDNA
MMAR_4577|M.marinum_M               GSRVGSRFGPYELVRLIGRGGMGEVYEAEDTRKRRVVALKLISTQYSGNP
MAV_4238|M.avium_104                AAQVGSWFGPYRLVRLLRQGGMGEVYEAEDTRKHRLVALKLISQQFSGNP
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       AVDPDGDRITYRRETIMTAKGVLTIGSTGAFNYTPTTAARHAAATSDPNL
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      ESPLDVLRRATEAG--------ASEYTLPREWGDWATRAKMPALXXXVRA
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        VFRARMQREADTAG--------RLTEPHIVPIHDYGEINGQFFVEMRMID
MMAR_4577|M.marinum_M               TFRARMQREADTAG--------RLTEPHIVPIHDYGEIDDQFFVEMRLID
MAV_4238|M.avium_104                EFSARLQREADIAG--------RLTEPHVVPIHDYGEIDGRFFVEMRLVD
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       AADSVTITARDRFGGVGAIVLTIPIAPTNTSPVGSAAGAGVTDPVTGVVR
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------MTSPISLGNAAP
TH_0100|M.thermoresistible__bu      AALVDILSGQEVSLFWSKNTIPQRLWPSQGCPAGQRGLLSGLQRLDNVQP
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------MN----------
MUL_4817|M.ulcerans_Agy99           ---------------------------------MVRAVIPVTRRLQHAG-
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        GTSLRALLKQYGPLTPARAVAIVRQIAAALDAAHANGVTHRDVKPENILV
MMAR_4577|M.marinum_M               GVSLRAMLTQFGPLTPARAVAIVRQIAAALDAAHSNGVTHRDVKPENILV
MAV_4238|M.avium_104                GIDLGSLLHREGPLAPPRAIAIIRQVAAALDAAHAAGVTHRDVTPGNILV
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       GTVTATDSDGDDLLFSGTTTTEKGSVVVDSIGTYTYTPTTAARHHVNAED
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      ---------------------ARYTAN--PSVAEGWHLRQVTAPSRLFGA
TH_0100|M.thermoresistible__bu      KPADGRTPHPMAAPMAGAHQQARYTPQNPPGAAPGWRLDRITGPSRLFGA
Mflv_1786|M.gilvum_PYR-GCK          ---------------------ARYAAQN-PTAAEGWTLRSVTAPSPLFGA
MUL_4817|M.ulcerans_Agy99           ----------------------HYPVTRAPNVAEGWTLTRLTAPSRLFGA
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        TASDFAYLVDFG--------IARAASDPGLTQTGTAVGTYNYMAPERFTG
MMAR_4577|M.marinum_M               ADNDFAYLVDFG--------IARAAADPGLTQGGMAVGTYNYMAPERFTG
MAV_4238|M.avium_104                TPSDFAYLADFG--------IARAASDPGLTQVGTAIGTYYYMAPERFTD
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       ATDADRRDSFVVTVTDGHGGTAQVLVSVAIAPSSNQAPGGVSYSANPNTD
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      NGLRTGPDGRVYVAQVTGSQISALDIVTGELQTVAARGGDIIAPDDVAFD
TH_0100|M.thermoresistible__bu      NGLRTGPDGRVYIAQVTGSQISALDIATGALETISPKGGDIISPDDVAFD
Mflv_1786|M.gilvum_PYR-GCK          NGLRTGPDGRIYIAQVTGSQISALDPATGALETVSAKGGDIIAPDDVAFA
MUL_4817|M.ulcerans_Agy99           NGLRTGPDGRVYIAQVTGSQISALDLSTGRLDTVCPKGGAIIAPDDLAFD
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        DEVTYRADIYALACVLGECLTGAPPYRADSVERLIAAHLMDPAPQPSQLR
MMAR_4577|M.marinum_M               NDVTYRADIYALACVLGECLTGAPPYRADSVERLIAAHLMEPPPRPSQLR
MAV_4238|M.avium_104                DEVTNSVDIYSLACVLTECLTGVPPYRADTVERLVAAHLTKTAPPLSQLR
MAB_2106c|M.abscessus_ATCC_199      ---------------------------MGNPSSIAMMDAMNRLPRRGMRG
Mvan_1720|M.vanbaalenii_PYR-1       TGVVEGRVTATDPEGDSLTFSGSAETGKGTVAVAPDGSFVYTPTDDARLS
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      IRGNLYATEVMDGRVSVREPNGTTRVLRDDVPSANGITFHEGRLFIGECR
TH_0100|M.thermoresistible__bu      PHGNLVATEVMEGRVSLRDTAGRARVLRDDIPSANGITFHRGRLFIGECR
Mflv_1786|M.gilvum_PYR-GCK          DDGTLFATEVMDGRVSAREPSGRTRVLRDDLPCANGITVDRGRLFVGECR
MUL_4817|M.ulcerans_Agy99           QDGNLYATEVMDGRVSVRAPDGHTRVLRDDIPSANGITFHQGRLFVGECR
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        PGRVPPALDQVIAKGMAKNPAERFMSAGDLAIAAHDALTTSEQHQATTIL
MMAR_4577|M.marinum_M               PGRVPAALDEVIAKGMAKNPDERYMSAGDLAIAAHEALTTPEQRQEATIL
MAV_4238|M.avium_104                PGGFPPALDRVIAKGMAKRPEDRYRTAGEFAAAAHEALTTSEQRKAATIL
MAB_2106c|M.abscessus_ATCC_199      IRGTVAALAVVITAAAAASSG---------------------------CS
Mvan_1720|M.vanbaalenii_PYR-1       AGAPGAPVASKEDSFVVDVSDGHGGTTSISVSVEIVPLIDNESPVAGTPI
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      EGGRLLEFDLAGGPPRVLLENVPSPNAMEVGPDGLLYFP-----------
TH_0100|M.thermoresistible__bu      EGGRLLEFSLNGDAPRVLLDNVPSPNAMEVGPDGLLYFP-----------
Mflv_1786|M.gilvum_PYR-GCK          DGGRLMELPLDGGEPRILLENLPSPNAMEVGPDGLLYYP-----------
MUL_4817|M.ulcerans_Agy99           DGGRLLELDLNGGAPRVLARNLPSPNAMEVGPDGLLYFP-----------
Mb0954c|M.bovis_AF2122/97           -------MLATPADTGLSQSESGIAGAGTGPPTPGAAR---WS-------
Rv0931c|M.tuberculosis_H37Rv        RRGDNATLLATPADTGLSQSESGIAGAGTGPPTPGAAR---WS-------
MMAR_4577|M.marinum_M               RQGDNMALMTPAVDPGAGGSWTNYSGSGAQPPAPQPVAPPPQY-------
MAV_4238|M.avium_104                RDGQIAALGAGAAE----QRSTHWPDSFAPSPS-----------------
MAB_2106c|M.abscessus_ATCC_199      SGGD----SENSADPRVITPASAAQSPPVTTAP-----------------
Mvan_1720|M.vanbaalenii_PYR-1       VGDPTPGTGVVSGTLGFTDPEGSSLAYTVTGPPAKGLVSIDTTGGFTYTP
                                                                   .                  

MSMEG_5629|M.smegmatis_MC2_155      ------------VMGANEIWRIHPD--GGTPE------------------
TH_0100|M.thermoresistible__bu      ------------VMGANEIWRIDPDQPGAAPQ------------------
Mflv_1786|M.gilvum_PYR-GCK          ------------LMTANEIWRIDPS--GGEPQ------------------
MUL_4817|M.ulcerans_Agy99           ------------VMGANEIWRIDPD--GGVPQ------------------
Mb0954c|M.bovis_AF2122/97           ------------PGDSATVAGPLAADSR--------------------GG
Rv0931c|M.tuberculosis_H37Rv        ------------PGDSATVAGPLAADSR--------------------GG
MMAR_4577|M.marinum_M               ------------PTGDETVARPVPASTTGWRSRPDVSDQRTQAAPVITGT
MAV_4238|M.avium_104                ---------------AETVVGPSPARAG----------------------
MAB_2106c|M.abscessus_ATCC_199      ---------------AGTVHR-----------------------------
Mvan_1720|M.vanbaalenii_PYR-1       NPEDRPEAGEAPGYDAFTVVATDPQGLAAQVTVDVVVAPLLPPSDGPVVG
                                                      :                               

MSMEG_5629|M.smegmatis_MC2_155      VVATGLGVPDAVKFGADGHLVSTQVASGQVLRIDPRS-------------
TH_0100|M.thermoresistible__bu      TVATGLGVPDAVKFDPAGHIVSTQVATGQVLRIDPRT-------------
Mflv_1786|M.gilvum_PYR-GCK          RVAADLGVPDAVKFDTDGFIVSTQVASGQVLRIDPRT-------------
MUL_4817|M.ulcerans_Agy99           CVAGDLRVPDAVKFDPHGHLVSTQVHSGEVLRINPRT-------------
Mb0954c|M.bovis_AF2122/97           NWPSQTGHSPAVPN------ALQASLGHAVPPAGNKR-------------
Rv0931c|M.tuberculosis_H37Rv        NWPSQTGHSPAVPN------ALQASLGHAVPPAGNKR-------------
MMAR_4577|M.marinum_M               SWPSQSGIRPAVGTGSSPSATPPASQPATAPPASPKKS------------
MAV_4238|M.avium_104                --APSSGLIRAAPTGSGRVYAPGPDFGRPVAPTDNKR-------------
MAB_2106c|M.abscessus_ATCC_199      ----IAGQASAVLFDTSTKTVSILADEGQIVTTVTRD-------------
Mvan_1720|M.vanbaalenii_PYR-1       TPPYDIDSVDEVTGVISGHVTAYTSNGTALTFAVAESPDVASGRVALDSA
                                               .        .              .              

MSMEG_5629|M.smegmatis_MC2_155      ------------GEQTVLAQLTPGLDNLTFADGRLFVSNFTGAITEIMGD
TH_0100|M.thermoresistible__bu      ------------GEQTVLATLTPGLDNLTFVGDRLFVSNFTGEITEILGD
Mflv_1786|M.gilvum_PYR-GCK          ------------GEKTVLAQLNPGLDNLTFVGDRLFASNFTGEITEIGRD
MUL_4817|M.ulcerans_Agy99           ------------GDRTVLAALHPGLDNLTFVGERLFVSSFTGEITEILGT
Mb0954c|M.bovis_AF2122/97           -----------KVWAVVGAAAIVLVA--IVAAAGYLVLRPSWSPTQASGQ
Rv0931c|M.tuberculosis_H37Rv        -----------KVWAVVGAAAIVLVA--IVAAAGYLVLRPSWSPTQASGQ
MMAR_4577|M.marinum_M               -----------RKNWIIGAAVVAVLL--VVAGATAFVLAKPKGSTEPRGQ
MAV_4238|M.avium_104                -----------KQWIIVGAVALVALVAFVVAVVGYLSTASSGPAKQAGGQ
MAB_2106c|M.abscessus_ATCC_199      -----------------------------DLDTVRRVTRLPSPATAAVGD
Mvan_1720|M.vanbaalenii_PYR-1       TGRWTFTPTASTLVSAWSSDTPTPVTFTIRVSDGEKSTDITVSATVSPSE
                                                                            .   .     

MSMEG_5629|M.smegmatis_MC2_155      GTTRDFLGGGLNWPLDLTVGADGAVYVADGTYFYRVG--PDGSLDTVGML
TH_0100|M.thermoresistible__bu      GSTRATLPGGLNWPLDLAVGADGALYVADGTYFYAVR--PDGSLQTVGML
Mflv_1786|M.gilvum_PYR-GCK          GQTSALLPGGLNWPLDLTV-SDGRLYVADGTYFYRVG--PDGALETVGML
MUL_4817|M.ulcerans_Agy99           GETRTTLPGGLTWPLGLAVAADGDLYIADGTYFYVLL--ADGTLRVGGML
Mb0954c|M.bovis_AF2122/97           TVLPFTGIDFRLSPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLP
Rv0931c|M.tuberculosis_H37Rv        TVLPFTGIDFRLSPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLP
MMAR_4577|M.marinum_M               VVLPFTGLNFRFAPGGVAVDANGTVYVTNQTMYGRVVALPAGSSTPTVKP
MAV_4238|M.avium_104                SVLPFNGIDFRLSPGGVTLDGAGNVYVTSEGMYGRVVKLAAGSGATTVLP
MAB_2106c|M.abscessus_ATCC_199      --------------------DRGTVYLSTAGGYFALD---IASGRADKVN
Mvan_1720|M.vanbaalenii_PYR-1       QAVINSVEYLGSEPSGVTVGPDGRMYVIDSGANTLSIINPADASMITVTV
                                                          * :*:               :       

MSMEG_5629|M.smegmatis_MC2_155      ----------------------------------FSPGYPGFLRGVIAGG
TH_0100|M.thermoresistible__bu      ----------------------------------FSSGYPGFIRGVEPSG
Mflv_1786|M.gilvum_PYR-GCK          ----------------------------------FSPGYPGFLRGVVAVG
MUL_4817|M.ulcerans_Agy99           ----------------------------------FSAGYPGFLRGVAALG
Mb0954c|M.bovis_AF2122/97           ----------------------------------FNGLYQ--PQGLAVDG
Rv0931c|M.tuberculosis_H37Rv        ----------------------------------FNGLYQ--PQGLAVDG
MMAR_4577|M.marinum_M               ----------------------------------FNGLYE--PQGVAVDT
MAV_4238|M.avium_104                ----------------------------------FNGLYQ--PQGLAVDG
MAB_2106c|M.abscessus_ATCC_199      ----------------------------------ISGHENTEFSAITRRP
Mvan_1720|M.vanbaalenii_PYR-1       GKNPTSVASDDLGRLWVTNSGDHTVTVLNAEAEILRTVQVGLVPASVVIR
                                                                      :         .     

MSMEG_5629|M.smegmatis_MC2_155      AGEFIVTTAADTVARYRPGSD-ESEPLAAGVDQPYGVALAPDGTVVVVEQ
TH_0100|M.thermoresistible__bu      PGEFVVTTSGGQVTRYRPADS-ESEVLADGLDQLYGLALAGDGTVVCAEQ
Mflv_1786|M.gilvum_PYR-GCK          GDEFVVTTSGGQVARYRPGAG-ETDFLATDFDQLYGVDVAGDGSIVFAEL
MUL_4817|M.ulcerans_Agy99           SGEFAVTTSNGEVARYRPWAS-ETEVLATGLDQLYGVAVAGSGALFVAER
Mb0954c|M.bovis_AF2122/97           AGTVYVTDFNNRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADR
Rv0931c|M.tuberculosis_H37Rv        AGTVYVTDFNNRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADR
MMAR_4577|M.marinum_M               SGKIYVTDFNNRVVALAAGSNNQVELPFNGLNYPEGIAVDAQGNVYVADR
MAV_4238|M.avium_104                AGTVYVADFNNRVLSMAAGSNSQKELPFSGLNYPEGVAVDSQGGVYVADR
MAB_2106c|M.abscessus_ATCC_199      DGRIVLGSADGTVFTLD--LQNQVIAHAAGFAHIDSLAYQGN-TVAVLDR
Mvan_1720|M.vanbaalenii_PYR-1       GDLAYIANFGGNSLSVIDAADDYSVRSVDVGTNPIDIAIGSDGRIYVANF
                                     .   :    .                        .:    .  :   : 

MSMEG_5629|M.smegmatis_MC2_155      GAGRLLAVRPGS---VDVLADGLDTPVGVAIGPDGAPLVSVAGA--VVRV
TH_0100|M.thermoresistible__bu      GTGRLLAVRGGE---VEVLATGLTQPVGVALDPDGTPLVAESGAGRIVRV
Mflv_1786|M.gilvum_PYR-GCK          GTGRVLRLDDGR---VETLASGLRQPVGVAIDADGAPLVSESGAGRVVRV
MUL_4817|M.ulcerans_Agy99           GAGRVLSVRPDG---VEVMASGLSDPVGVAVTADGRCVVTEADAGRVRTL
Mb0954c|M.bovis_AF2122/97           GNNRVVKLAAGSKTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKL
Rv0931c|M.tuberculosis_H37Rv        GNNRVVKLAAGSKTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKL
MMAR_4577|M.marinum_M               GNNRVVKMPAGSTSQVVLPFNGLKNPDGVAVDSDGNVYVTDTDNNRVLQL
MAV_4238|M.avium_104                GNSRVLKLAAGSQNQTVLPFTGLNNPDGVAVDPAGNVYVADTDNNRVVKL
MAB_2106c|M.abscessus_ATCC_199      AQSSVTTLTAAGDGTAHALRAGEG-ATTMLADDKGRLLVADTRGGALLAF
Mvan_1720|M.vanbaalenii_PYR-1       GNGTISVLRPDDMDDVLLVDSGGEHPHGILVDDDGTVYVTHPLDDTVTVL
                                    . . :  :       .     *   .  :     *   *: .    :  .

MSMEG_5629|M.smegmatis_MC2_155      TGTGVERLVD-------------------GLHTPQGLLVRD-GALYLVDA
TH_0100|M.thermoresistible__bu      AGGRTDTVVD-------------------QLSCPQGILVRG-NQLYIVDA
Mflv_1786|M.gilvum_PYR-GCK          SSGAVDTVID-------------------GLQRPQGLHVRD-NRLYIVDA
MUL_4817|M.ulcerans_Agy99           G--DTGTLLD-------------------GLQCPQGVAICD-RQVYVIDS
Mb0954c|M.bovis_AF2122/97           EAESNNQVVLP----------------FTDITAPWGIAVDEAGTVYVTEH
Rv0931c|M.tuberculosis_H37Rv        EAESNNQVVLP----------------FTDITAPWGIAVDEAGTVYVTEH
MMAR_4577|M.marinum_M               DAGTSNQSVLP----------------FSNLTAPWGITVDSAGNVYVTEH
MAV_4238|M.avium_104                DAASNTQSELP----------------FHDLSVPWGIAVDNGGTVYVTEH
MAB_2106c|M.abscessus_ATCC_199      GLADSLILRQR----------------YPVPGAPYGLAYSA-TLIWVSQT
Mvan_1720|M.vanbaalenii_PYR-1       NPAPVNRFSLRSLFSADATSGQYTYRSVTVIGAPTKITKDTAGRIYVTNS
                                                                     *  :       ::: : 

MSMEG_5629|M.smegmatis_MC2_155      GSKDLISVDLTTGVRTTIASGLP----------------VGPPPGVVPKP
TH_0100|M.thermoresistible__bu      TAKELLAVDLATGQRQRIATGLP----------------VGSPPGVQPKP
Mflv_1786|M.gilvum_PYR-GCK          GAKELVEFDLGTKARSTIATGLP----------------VGPPPGVEPKP
MUL_4817|M.ulcerans_Agy99           GAKQLVAVDLGSRTRHTIAWDLP----------------VGAPAGVTPNP
Mb0954c|M.bovis_AF2122/97           NTNQVVKLLAGSTTST----------------------------------
Rv0931c|M.tuberculosis_H37Rv        NTNQVVKLLAGSTTST----------------------------------
MMAR_4577|M.marinum_M               DNNAVAKLAAGATTST----------------------------------
MAV_4238|M.avium_104                DKNDVVKYPPGATSGT----------------------------------
MAB_2106c|M.abscessus_ATCC_199      ATNTVIGYDLSTGIPEE---------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       SGATITVLDPLTLAANEIHTGANPSSVYVDRFGNLYVTNAGQKTVAVIHA
                                        :      :                                      

MSMEG_5629|M.smegmatis_MC2_155      LKGMPPFSGPQGPFAGIAAGPDGTLYISADGDGSVLALQRR---------
TH_0100|M.thermoresistible__bu      LKGMPPFSGPQGPFAGITAGPDGTLYLSADGDGSVLALRRTR--------
Mflv_1786|M.gilvum_PYR-GCK          LKGMPPFSGPQGPFAGITSGPDGTLFVSADGDGSVLAVSRG---------
MUL_4817|M.ulcerans_Agy99           LRGMPPFSGPEGPFAAITPGPDATLYISADADGSVLALRRES--------
Mb0954c|M.bovis_AF2122/97           ---VLPFTGLNTPLA-VAVDSDRTVYVADRGNDRVVKLTS----------
Rv0931c|M.tuberculosis_H37Rv        ---VLPFTGLNTPLA-VAVDSDRTVYVADRGNDRVVKLTS----------
MMAR_4577|M.marinum_M               ---ELPFTGLNTPLS-VAVDKKGNVYVADRGNGRVLKLAQGS--------
MAV_4238|M.avium_104                ---VLPFTALNTPLA-VAVDRDQSVYVADRGDDRVVKLAQ----------
MAB_2106c|M.abscessus_ATCC_199      ---RARFATVRQPNSLVSDGS--TLFVASGAGDGIQATDIRSLG------
Mvan_1720|M.vanbaalenii_PYR-1       QTRNITTYRADVKTSQVTTDDDGNLVMVSTYDGHRSVLSTDTVSTGADAL
                                                  : :: .   .: :    ..                 

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       QIANVWGSYGSLVASPDGKWLYAVRNRRVDTTGGLYPNRYDIVAIDTSNN
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       SVRTFAWDAHINGSMVLTMNRDGDRLYAAYYTLDPEVFDGVVAKVAIINV
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       DGSTLQLDGAPVELNLGSTTAFVSDIVVNPAGTKVFVIGDRLAVPGQWDA
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       PEGQWNMYGNLWMVDLENDRAVSRPPIPRPLQAEGGVPDLAISPDGRYAY
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       LVMTPLPGWEGNHYLGIFDTQSFALTTVLLGHFEAPNGVRRLVVSPDGTR
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       IYLSDGQIVGVTGTQHELLEDRIQGIDQERFVDIAINPEGTRLYTTTWDG
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       VLTTIDTSTGLPVGNPTDLGNRAWGMTFGPKGDTLYVRRGVDYVASHRAP
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       QSIADLWENVRDLPNGDNEGIFTQVVRHADGTNRMVVYLGGTNPRNWLVG
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       EQAIGENVVSELGILKDEHLGAITRALAHCRNDATCGDIADVMLVGFSQG
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       GIDGQNFASQWDRLGFGVQLSALVTFGSPITKNPNVPTLHIQDIDDEVVN
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      --------------------------------------------------
TH_0100|M.thermoresistible__bu      --------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          --------------------------------------------------
MUL_4817|M.ulcerans_Agy99           --------------------------------------------------
Mb0954c|M.bovis_AF2122/97           --------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4577|M.marinum_M               --------------------------------------------------
MAV_4238|M.avium_104                --------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       TELLARLAATVQYVPMPSWLRINFAAATVTAMARGQLYQGAADTDISVLD
                                                                                      

MSMEG_5629|M.smegmatis_MC2_155      -------------------------------------------------
TH_0100|M.thermoresistible__bu      -------------------------------------------------
Mflv_1786|M.gilvum_PYR-GCK          -------------------------------------------------
MUL_4817|M.ulcerans_Agy99           -------------------------------------------------
Mb0954c|M.bovis_AF2122/97           -------------------------------------------------
Rv0931c|M.tuberculosis_H37Rv        -------------------------------------------------
MMAR_4577|M.marinum_M               -------------------------------------------------
MAV_4238|M.avium_104                -------------------------------------------------
MAB_2106c|M.abscessus_ATCC_199      -------------------------------------------------
Mvan_1720|M.vanbaalenii_PYR-1       IFAVHGNRATYQQLASEMDARTGTDFAALGPVRTFFGGTALIPGDPTPL