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MRTEDDSWDVTTSVGSTGLLVAAARALETQKADPLAIDPYAEVFCRAAGGEWADVLDGKLPDHYLTTGDF GEHFVNFQGARTRYFDEYFSRATAAGMKQVVILAAGLDSRAFRLQWPIGTTIFELDRPQVLDFKNAVLAD YHIRPRAQRRSVAVDLRDEWQIALCNNGFDANRPSAWIAEGLLVYLSAEAQQRLFIGIDTLASPGSHVAV EEATPLDPCEFAAKLERERAANAQGDPRRFFQMVYNERWARATEWFDERGWRATATPLAEYLRRVGRAVP EADTEAAPMVTAITFVSAVRTGLVADPARTSPSSTSIGFKRFEAD
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0917c | - | - | 100% (325) | hypothetical protein Mb0917c |
M. bovis AF2122 / 97 | Mb0289 | - | e-117 | 69.10% (301) | hypothetical protein Mb0289 |
M. bovis AF2122 / 97 | Mb0151 | - | 9e-61 | 43.18% (308) | hypothetical protein Mb0151 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0743 | - | 4e-67 | 44.37% (302) | putative methyltransferase |
M. tuberculosis H37Rv | Rv0893c | - | 0.0 | 100.00% (325) | hypothetical protein Rv0893c |
M. leprae Br4923 | MLBr_02640 | - | 2e-61 | 43.19% (301) | hypothetical protein MLBr_02640 |
M. abscessus ATCC 19977 | MAB_4328c | - | 2e-87 | 53.31% (302) | hypothetical protein MAB_4328c |
M. marinum M | MMAR_0539 | - | 1e-113 | 66.00% (300) | O-methyltransferase |
M. avium 104 | MAV_4873 | - | 1e-117 | 68.00% (300) | methyltransferase, putative, family protein |
M. smegmatis MC2 155 | MSMEG_0614 | - | 6e-93 | 56.38% (298) | methyltransferase |
M. thermoresistible (build 8) | TH_4502 | - | 6e-65 | 44.94% (316) | PUTATIVE methyltransferase |
M. ulcerans Agy99 | MUL_4762 | - | 6e-63 | 45.00% (300) | O-methyltransferase |
M. vanbaalenii PYR-1 | Mvan_0104 | - | 1e-66 | 43.75% (304) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb0917c|M.bovis_AF2122/97 ---MRTEDDSWDVTTSVGSTGLLVAAARALETQKADPLAIDPYAEVFCRA Rv0893c|M.tuberculosis_H37Rv ---MRTEDDSWDVTTSVGSTGLLVAAARALETQKADPLAIDPYAEVFCRA MMAR_0539|M.marinum_M ---MRSEGDSWDITTSVGSTALFVATARALEALKPDPLAVDPYAELFCRA MAV_4873|M.avium_104 ---MRSEGDTWDITTSVGSTALFVATARALEAQKPDPLAVDPYAEIFCRA MAB_4328c|M.abscessus_ATCC_199 ---MRTDRDNWDINTSVGSTALFVAASRALEATKPAPLAADQYAEVFCRA MSMEG_0614|M.smegmatis_MC2_155 ---MRTDNDQWDITISVGQTALFVAASRALEARKPHPLAVDHYAEVFCRA Mflv_0743|M.gilvum_PYR-GCK MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALINDPYAKVLVEG Mvan_0104|M.vanbaalenii_PYR-1 MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDDPYAKILVAG TH_4502|M.thermoresistible__bu MSSLRTDDDTWDIATSVGSTAVMVAASRAAETEREDALIRDPYAKVLVAG MLBr_02640|M.leprae_Br4923 ---MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTN MUL_4762|M.ulcerans_Agy99 ---MRTHDDTWDIRTSVGATAVMVAAARAVETSKPEPLIRDPYARMLVTN :*:. * **: *** *.::**::** *: : .* * **.:: Mb0917c|M.bovis_AF2122/97 AGGE--WADVLD----GKLPDHYLTTGDFGEHFVNFQGARTRYFDEYFSR Rv0893c|M.tuberculosis_H37Rv AGGE--WADVLD----GKLPDHYLTTGDFGEHFVNFQGARTRYFDEYFSR MMAR_0539|M.marinum_M VGGS--WADVLD----GNAADHELQSDDFGKHFVNFQGARTKYFDAYFRR MAV_4873|M.avium_104 VGGS--AADVLD----GKDPDHQLKTDDFGVHFVNFQGARTKYFDEYFRR MAB_4328c|M.abscessus_ATCC_199 AGGE--WAELVA----GGVPEHPLRSEDFGQYFVSFQGARTRYFDTYFGK MSMEG_0614|M.smegmatis_MC2_155 AGGD--WVAAVE----GTDPEHPLQT-EFGVDFVNFQGARTKYFDDYFRR Mflv_0743|M.gilvum_PYR-GCK AGAG-AWRFIADEDLVAKASESDTEVGALFEHMKNYQAVRTHFFDAFFSA Mvan_0104|M.vanbaalenii_PYR-1 AGNG-AWQYIADDGFVAKVTESDPEIGPLFEHMKNYQAVRTHFFDAFFAA TH_4502|M.thermoresistible__bu AGTG-VWELILDDDFTAKIEAADPETAAIFDHMGNYQAVRTHFFDTYFAR MLBr_02640|M.leprae_Br4923 TGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFNN MUL_4762|M.ulcerans_Agy99 ANAGVIWEAMLDQEMVAKVEAIDAETAATVEHMRSYQAVRTNFFDTYFAD .. . : .:*..**.:** :* Mb0917c|M.bovis_AF2122/97 ATAAGMKQVVILAAGLDSRAFRLQWPIGTTIFELDRPQVLDFKNAVLADY Rv0893c|M.tuberculosis_H37Rv ATAAGMKQVVILAAGLDSRAFRLQWPIGTTIFELDRPQVLDFKNAVLADY MMAR_0539|M.marinum_M AVEAGVRQVVVLAAGLDSRAYRLSWPDGTTIFELDRPQVLDFKREVLGGH MAV_4873|M.avium_104 AADAGVRQVVILAAGLDSRAYRLDWPAATTIFELDQPQVLDFKREVLAGV MAB_4328c|M.abscessus_ATCC_199 AIEAGVKQVVILASGLDSRAYRLDWAPGTTVFELDQPLVHQFKREALDQH MSMEG_0614|M.smegmatis_MC2_155 VADAGVRQVVLLAAGLDSRAYRLPWADGTVVYELDVPKVLEFKREVLRRH Mflv_0743|M.gilvum_PYR-GCK AVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVLDYKSSTLAAH Mvan_0104|M.vanbaalenii_PYR-1 AVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLAYKSSTLASH TH_4502|M.thermoresistible__bu AAEAGIRQVVILASGLDSRAYRLPWPDGTVVYEIDQPKVLEYKSATLAAH MLBr_02640|M.leprae_Br4923 AVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAEH MUL_4762|M.ulcerans_Agy99 AVAAGIRQVVILASGLDSRAYRLDWPAGTTVYEIDQPQVLAYKSATLAEN . *::*.*:**:******:** *. .*.::*:* * * :* .* Mb0917c|M.bovis_AF2122/97 HIRPRAQRRSVAVDLRDEWQIALCNNGFDANRPSAWIAEGLLVYLSAEAQ Rv0893c|M.tuberculosis_H37Rv HIRPRAQRRSVAVDLRDEWQIALCNNGFDANRPSAWIAEGLLVYLSAEAQ MMAR_0539|M.marinum_M GVRPRTERREIAVDLRDDWPQALRDSGFDAEAPSAWIAEGLLIYLPAAAQ MAV_4873|M.avium_104 DAHPRAERREIAVDLREDWPQALRDSGFDPDKPSAWIAEGLLIYLPASAQ MAB_4328c|M.abscessus_ATCC_199 GAEPKAVRAEISVDLREDWGKALQDKGFDPSEPSAWLVEGLLIYLPADAQ MSMEG_0614|M.smegmatis_MC2_155 GATPTAERREVPVDLRDDWPAALRANGFDASQPSAWIAEGLLIYLPADAQ Mflv_0743|M.gilvum_PYR-GCK GVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEGLLMYLPADAQ Mvan_0104|M.vanbaalenii_PYR-1 GVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGLLMYLPADAQ TH_4502|M.thermoresistible__bu GVQPAADRREVAVDLRHDWPKALRAKGFDPQQRTAWLAEGLLMYLPADAQ MLBr_02640|M.leprae_Br4923 GVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPATAQ MUL_4762|M.ulcerans_Agy99 GVTPAAERREVAIDLRQDWPSALRAAGFDPSARTAWLAEGLLMYLPAEAQ * : * .:.:***.:* ** ***. :**:.****:**.* ** Mb0917c|M.bovis_AF2122/97 QRLFIGIDTLASPGSHVAVEEATPLDP---CEFAAKLERERAANAQGDPR Rv0893c|M.tuberculosis_H37Rv QRLFIGIDTLASPGSHVAVEEATPLDP---CEFAAKLERERAANAQGDPR MMAR_0539|M.marinum_M EQLFTGIDSLACLGSHVAVEDGAPLPD---AEFAAKLEEERAAVAAGGER MAV_4873|M.avium_104 EQLFTGIDALAGHGSHVAVEEGAPMTP---EDFEAAVAAERAANEQGEQR MAB_4328c|M.abscessus_ATCC_199 ERLFESIDQLAAPGSFVGIEQMTTYAD---VVFAMLVAGANESGDQANSD MSMEG_0614|M.smegmatis_MC2_155 ELLFAGIDALSAPGSFVAIEESAPMPM---DVFEVKRAEALASGD-PNS- Mflv_0743|M.gilvum_PYR-GCK DRLFAQITELSAPGSQVAAESMGVHAPDRRERMRERFASIASQIDIEP-M Mvan_0104|M.vanbaalenii_PYR-1 DRLFAQITELSAPGSRVAAESMGIHAQDRRERMRERFASITAQFDVEP-M TH_4502|M.thermoresistible__bu DRLFENITALSAPGSRLAVETAAEEPVDRREQMRARMERIASQFGLEKAL MLBr_02640|M.leprae_Br4923 DGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDALGFEQAV MUL_4762|M.ulcerans_Agy99 DRLFTQIGELSCAGSRIAAETAGNHADERREQMRERFRKVAQTLGLEQTI : ** * *: ** :. * : Mb0917c|M.bovis_AF2122/97 RFFQMVYNE-RWARATEWFDERGWRATATPLAEYLRRVGRAVPE------ Rv0893c|M.tuberculosis_H37Rv RFFQMVYNE-RWARATEWFDERGWRATATPLAEYLRRVGRAVPE------ MMAR_0539|M.marinum_M PFFQLLYNE-RCAPAADWFSEHGWTALGTPLNNYLREVGRPVPG------ MAV_4873|M.avium_104 MFFQLVYNE-QCAPAAEWFGSRGWTAVPTPLADYLRQVGRPVPG------ MAB_4328c|M.abscessus_ATCC_199 -FFSLIYNE-QRSEAATWFRCHGWDSERTELLDYLNFSGRTLPE------ MSMEG_0614|M.smegmatis_MC2_155 -FFALVFNE-QCAPGEQWFSERGWTASTTTLNECLHEVGRPAPA------ Mflv_0743|M.gilvum_PYR-GCK DITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRRLDRYV-------- Mvan_0104|M.vanbaalenii_PYR-1 DITELTYEDPDRADVAQWLTAHGWRAEAVPSQDEMRRLHRLV-------- TH_4502|M.thermoresistible__bu DVAQLMYDDPDRADVPEWLTGHGWRTEWVSAPDEMRRLDRFVAAAMPPGD MLBr_02640|M.leprae_Br4923 DVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDG------ MUL_4762|M.ulcerans_Agy99 DVHELIYHDPDRAPLGQWLNEHGWRANAQNACDEMHRVGRWVEG------ . : :.: : *: :** : : :. * Mb0917c|M.bovis_AF2122/97 -ADTEAAPMVTAITFVSAVRTGLVADPARTSPSSTSIGFKRFEAD Rv0893c|M.tuberculosis_H37Rv -ADTEAAPMVTAITFVSAVRTGLVADPARTSPSSTSIGFKRFEAD MMAR_0539|M.marinum_M -PGSEVAAMFARNTLMSATKP------------------------ MAV_4873|M.avium_104 -PDTEAGPMIARNTLVSAVRA------------------------ MAB_4328c|M.abscessus_ATCC_199 -PSQPAWYMFNSISLVSAVKG------------------------ MSMEG_0614|M.smegmatis_MC2_155 -PDSEAAQMTGSISLMWARKG------------------------ Mflv_0743|M.gilvum_PYR-GCK --EVADSDGQSFSTFTTGTKL------------------------ Mvan_0104|M.vanbaalenii_PYR-1 --EIADGDDQSFSTFTTAVKR------------------------ TH_4502|M.thermoresistible__bu DADAADLDDTAFSKFVTAERPS----------------------- MLBr_02640|M.leprae_Br4923 -VPMAD-DKDAFAEFVTAHRL------------------------ MUL_4762|M.ulcerans_Agy99 -VPMAD-DKQAYSDFVTAERL------------------------ : . :