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VRCGVSAGSANGKPNRWTLRCGVSAGHRGSVFLLAVLLAPVVLTSCTWRGIANVPLPVGRGMGPDRMTIY VQMPDTLALNTNSRVRVADVWVGTVRDISLRNWIATLTLELEPTVRLPANATAKIGQTSLLGTQHVELAA PPIPSPQPLKSGDTIGLKNSSAYPTVERTLASVALILTGGGIVNLDVI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0609 | lprL | - | 100% (188) | MCE-family lipoprotein LprL |
| M. bovis AF2122 / 97 | Mb0179 | lprK | 6e-58 | 69.03% (155) | MCE-family lipoprotein LprK |
| M. bovis AF2122 / 97 | Mb3525c | lprN | 3e-20 | 35.54% (166) | MCE-family lipoprotein LprN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0707 | - | 2e-57 | 69.23% (156) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv0593 | lprL | 1e-106 | 100.00% (188) | MCE-family lipoprotein LprL |
| M. leprae Br4923 | MLBr_02593 | lprK | 4e-52 | 63.87% (155) | putative lipoprotein |
| M. abscessus ATCC 19977 | MAB_4149c | - | 2e-24 | 40.54% (148) | MCE-family protein LprN |
| M. marinum M | MMAR_0416 | lprK | 1e-55 | 59.69% (191) | MCE family lipoprotein LprK |
| M. avium 104 | MAV_4547 | - | 1e-66 | 78.66% (164) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_0138 | - | 2e-50 | 61.02% (177) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_3924 | - | 3e-56 | 65.43% (162) | PUTATIVE virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_1066 | lprK | 2e-54 | 60.44% (182) | MCE family lipoprotein LprK |
| M. vanbaalenii PYR-1 | Mvan_0138 | - | 3e-57 | 69.23% (156) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0609|M.bovis_AF2122/97 -------MRCGVSAGSANGKPNRWTLRCGVSAGHRGSVFLLAVLLAPVVL
Rv0593|M.tuberculosis_H37Rv -------MRCGVSAGSANGKPNRWTLRCGVSAGHRGSVFLLAVLLAPVVL
MAV_4547|M.avium_104 ---------MVFAAHTAGAGP---VMRRVAVAGRRALVVALAAMLT----
Mflv_0707|M.gilvum_PYR-GCK -------------------------MSRLGTLAKRAVALGAAALVLT---
Mvan_0138|M.vanbaalenii_PYR-1 -------------------------MGKWTRLARRTVALAAAAVVLT---
MSMEG_0138|M.smegmatis_MC2_155 -------MRLLKGFP---------KMRNWTRVGRRTAVLAAVALVLT---
MMAR_0416|M.marinum_M MRRGVSVMGAIGKSKQSAARRGVGAMRAVSRRAWQGLALLMVALVLS---
MUL_1066|M.ulcerans_Agy99 -------MGAIGKSKQSTARRGVGAMRAVSRRAWQGLALLMVALVLS---
MLBr_02593|M.leprae_Br4923 MRR---AMSVVHTSR-------------VRHQTWRGLVMLVAALLLS---
TH_3924|M.thermoresistible__bu -------------------------MSALRRAARLLAALSVIVALTS---
MAB_4149c|M.abscessus_ATCC_199 ----------------------------MSRNVLRAAVMGVGVAVVVS--
.. . :
Mb0609|M.bovis_AF2122/97 TSCTWRGIANVPLPVGRGMGPDRMTIYVQMPDTLALNTNSRVRVADVWVG
Rv0593|M.tuberculosis_H37Rv TSCTWRGIANVPLPVGRGMGPDRMTIYVQMPDTLALNTNSRVRVADVWVG
MAV_4547|M.avium_104 -SCTWRGIADVPLPVGRGTGGDHMTIYVQMPDTLALNTNSRVRVADVWVG
Mflv_0707|M.gilvum_PYR-GCK SCGSWKGIANIPLPGGPGTGSERTTIYVQMPDTLALNVNSRVRVADVYVG
Mvan_0138|M.vanbaalenii_PYR-1 SCGSWKGISNVPLPGGPGSGSERTTIYVQMPDTLALNVNSRVRVADVYVG
MSMEG_0138|M.smegmatis_MC2_155 SCGQWRGIANVPLPGGPGTESGSMTLYVQMPETLALNANSRVRVRDVFVG
MMAR_0416|M.marinum_M SCG-WRGISNVAIPGAPGTGKGSYTVYVQVPDTLAINGNSKVMVADVPVG
MUL_1066|M.ulcerans_Agy99 SCG-WRGISNVAIPGAPGTGKGSYTVYVQVPDTLAINGNSKVMVADVPVG
MLBr_02593|M.leprae_Br4923 SCG-WRGISNVSIPGGPGSGKGAYTIYVQVPDTLAINGNSKVMVADVTVG
TH_3924|M.thermoresistible__bu -CGSWRGIANVPLPSGPGTGPGSYTVYVQVEDALALNVNSRVRVADVYVG
MAB_4149c|M.abscessus_ATCC_199 -GCQFNGLNSLNLPGTAGHGSRSYTVTVELPDVTTLPQNSPVMVDDVTVG
:.*: .: :* * *: *:: :. :: ** * * ** **
Mb0609|M.bovis_AF2122/97 TVRDISLRN-----WIATLTLELEPTVRLPANATAKIGQTSLLGTQHVEL
Rv0593|M.tuberculosis_H37Rv TVRDISLRN-----WIATLTLELEPTVRLPANATAKIGQTSLLGTQHVEL
MAV_4547|M.avium_104 TVRAITLKD-----WVATLRLDLDPGVRLPANATAKIGQTSLLGTQHVEL
Mflv_0707|M.gilvum_PYR-GCK RVRAIELRN-----WVATLTLDLEPNIALPVNTQAKIGQTSLLGSQHVQL
Mvan_0138|M.vanbaalenii_PYR-1 RVRAIELKN-----WIATLTLDLEPSVQLPVNTLARIGQTSLLGSQHVQL
MSMEG_0138|M.smegmatis_MC2_155 RVRKIELIN-----WVPTLTVDVEPGIKLPKNTLAKIGQTSLLGSQHVEL
MMAR_0416|M.marinum_M SIRNIQLKN-----WVATLTLGIDQGVKLPKNALAKIGQTSLLGSQHVEL
MUL_1066|M.ulcerans_Agy99 SIRNIQLKN-----WVATLTLGIDQGVKLPKNALAKIGQTSLLGSQHVEL
MLBr_02593|M.leprae_Br4923 SIRAINLKN-----WVATLTLGLNKDVQLPKNTTAKIGQTSLLGSQHVEL
TH_3924|M.thermoresistible__bu TVRSIDLVD-----WVGTLTISLDPAVRLPRNATAKIGQTSLLGTQHVEL
MAB_4149c|M.abscessus_ATCC_199 SVSGIDAFQKPDGSWYAGVKVSLEPEVHLPANAVAKVAQTSLLGSQHIEL
: * : * : : :: : ** *: *::.******:**::*
Mb0609|M.bovis_AF2122/97 AAPP-IPSPQPLKSGDTIGLKNSSAYPTVERTLASVALILTGGGIVNLDV
Rv0593|M.tuberculosis_H37Rv AAPP-IPSPQPLKSGDTIGLKNSSAYPTVERTLASVALILTGGGIVNLDV
MAV_4547|M.avium_104 AAPK-NPSVQRLKSGDTILLQNSSAYPTVERTLASVAVILNGGGIANLDA
Mflv_0707|M.gilvum_PYR-GCK DLPP-DPSPQRLESGDTITLENASAFPTTERVLASIASILTGGGVANLET
Mvan_0138|M.vanbaalenii_PYR-1 DLPP-DPSPQKLKSGDVIPLANASAFPTTERVLASISSILTGGGVANLET
MSMEG_0138|M.smegmatis_MC2_155 NPPE-DPSSELLRDGDTIPLAQSSAYPTIERTLAGISGILTGGGIPNIEV
MMAR_0416|M.marinum_M AAPP-NPSSQLLKNGDTIPLKNSSAYPNTEQTLASISLILRGGGIPNLEV
MUL_1066|M.ulcerans_Agy99 AAPP-NPSSQLLKNGDTIPLKNSSAYPNTEQTLASISLILRGGGIPNLEV
MLBr_02593|M.leprae_Br4923 AAPA-NPSLELLKNGDTIPLKNSSVFPTTEQTLASLSLILRGGGIPNLET
TH_3924|M.thermoresistible__bu AAPA-EPAPEPLRDGDTIPLRHTSAFPTTERTLAGIATVLRGGGVGNLEY
MAB_4149c|M.abscessus_ATCC_199 AAPVGEPAVGKLTGGATIPLSRTGKYPSTEEVLSALSVVVNKGNLGALQD
* *: * .* .* * .:. :*. *..*:.:: :: *.: ::
Mb0609|M.bovis_AF2122/97 I-------------------------------------------------
Rv0593|M.tuberculosis_H37Rv IQTEILNILDGHAGQIREFLERLATFTAELNNQRGDLTRAIDSTNQLLTI
MAV_4547|M.avium_104 IQTEVLNILDGHAGQIREFLGRLDTFVTELSRQRDDLTRAIDSSNELLTV
Mflv_0707|M.gilvum_PYR-GCK IQSEVYNVLNGRADQIRDFLNQLDTFTAELNQQRDDITRAIDSTNRLLTI
Mvan_0138|M.vanbaalenii_PYR-1 IQTEIYNVLNGRADQIREFLGRLDTFTEELNRQRDDITRAIDSTNRLLAI
MSMEG_0138|M.smegmatis_MC2_155 IQTEVFNILNGRADQIREFLNQLDTFTDELNQQREEITRAIDSTNRLLNI
MMAR_0416|M.marinum_M LQNEVYDIFHGRGDQIRGFLTRLDTFTRQLNEQRDDITHAIDSTNRLMAY
MUL_1066|M.ulcerans_Agy99 LQNEVYDIFHGRGDQIRGFLTRLDTFTRQLNEQRDDITHAIDSTNRLMAY
MLBr_02593|M.leprae_Br4923 LTNEVFNIFHGRADQIHAFLTKLDTFASQLNQQRDDITHAIDSTNRLLTY
TH_3924|M.thermoresistible__bu LQNEVHAMLSGNAEQIGEFLDRLAVFTASLNDQIDQIDRAISSTRRLAGV
MAB_4149c|M.abscessus_ATCC_199 ITDETYNLFKGRTGNLTQVLPKLATLISSLNSQRDDIISAIEGIDKFSRV
:
Mb0609|M.bovis_AF2122/97 --------------------------------------------------
Rv0593|M.tuberculosis_H37Rv IANRNDTLDRVLTDVPPLIEHFADTGQLFADATESLGRFSEVANRALAAT
MAV_4547|M.avium_104 FANRRDTLDRVLTELPPLIRHFADTRELFADATESLGRFSDAADRALTDT
Mflv_0707|M.gilvum_PYR-GCK VAQRNETLDAVLTEFPPLIKHFADTRDLFGDAIESLGRISNAAVAALEPA
Mvan_0138|M.vanbaalenii_PYR-1 VGQRNQTLDAVLTEFPPLIQHFADTRDLFADAVESLGRISNAAVDALAPA
MSMEG_0138|M.smegmatis_MC2_155 VSQRNDTLDRVLTEFPPLIQHFAETRDLFADAVTALGRLSAAADETLSGS
MMAR_0416|M.marinum_M VGGRADVVDRALTDLPPLIKHFADTRDLLINAVNSVGQLSDVTGRYLSEA
MUL_1066|M.ulcerans_Agy99 VGGRADVVDRALTDLPPLIKHFADTRDLLINAVNSVGQLSDVTGRYLSEA
MLBr_02593|M.leprae_Br4923 VGGRSDVLDQILTDIPPLIKHFADTKNLLINAVGSVGQLSQAVDQYLSEA
TH_3924|M.thermoresistible__bu VAERSATLERVLTEVPPLIEHFAAQRELFVDGMEALGRFAHITDEALTAA
MAB_4149c|M.abscessus_ATCC_199 LAEHKESLGRAIDSIEPALKVLNENRANIIEAFRSVGNLAKITDRVLRTT
Mb0609|M.bovis_AF2122/97 --------------------------------------------------
Rv0593|M.tuberculosis_H37Rv RPNLHQTLQSLQRPLRQLERASPYVVGALKLGLTAPFNIDEVPNVIRGDY
MAV_4547|M.avium_104 RANLYRSLLSLQRPLRQLVPAAPFVAGALKLGLTAPFNIDDVAQVIRGDY
Mflv_0707|M.gilvum_PYR-GCK NGDMNQNLQNLQRPLRELGKSGPYLLGALKIFLTAPYSIENLPKAIRGDY
Mvan_0138|M.vanbaalenii_PYR-1 SDDINTNLANLQRPLRELGKSGPYLLGALKIFLTAPYNIENVPKAIRGDY
MSMEG_0138|M.smegmatis_MC2_155 NANLHTNLQNLQRPLKQLGRAAPYLVGALKLILTVPFNIDNIPKAIRGDY
MMAR_0416|M.marinum_M RGNLHTDLQSLQCPLKELGRGSQYLIGALKLILTQPFDIDAVPKIFRGDY
MUL_1066|M.ulcerans_Agy99 RGNLHTDLQSLQCPLKELGRGSQYLIGALKLILTQPFDIDAVPKIFRGDY
MLBr_02593|M.leprae_Br4923 RGPLHTDLQALACPLRELGRGAPYFIGAMKLILTQPYDVDTVPKIMRGDY
TH_3924|M.thermoresistible__bu RADLHTNLRLLQRPLRELARAAPYLPEALQLLLTLPFTIDNVDKVVRGDY
MAB_4149c|M.abscessus_ATCC_199 KDDIVADLKGLYPVVRALAENRDVLIDSLDLLPTFPFSTKYLRNAVRGDY
Mb0609|M.bovis_AF2122/97 --------------------------------------------------
Rv0593|M.tuberculosis_H37Rv VNVSATFDVTLSALDNALLSGTGISGMLRALEQAWGRD---PDTMIPDVR
MAV_4547|M.avium_104 VNVSAALDLTLSTIDNTMLTGTGLSGALRALEQSWGRD---PATMIPDVR
Mflv_0707|M.gilvum_PYR-GCK VNVSLTVDLTLSAIDNGFFSGTGISGMLRALEQAWGRD---PATMIPDVR
Mvan_0138|M.vanbaalenii_PYR-1 INVSLTVDLTLSAIDNGFFSGTGISGMLRALEQAWGRD---PATMIPDVR
MSMEG_0138|M.smegmatis_MC2_155 INVSLKLDLTLSSVDNAFLSGTGVSGMLRALEQAWGRD---PATMIPDVR
MMAR_0416|M.marinum_M QNVSATLDVTFSAMDNAVLTGTGFSGALRALEQSFGRD---PETMIPDVR
MUL_1066|M.ulcerans_Agy99 QNVSAALDVTFSAMDNAVLTGTGFSGALRALEQSFGLD---PETMIPDVR
MLBr_02593|M.leprae_Br4923 QNVSLTLDVTYSAMDNAVLTGTGLSGALRALEQSFGRD---PETMIPDVR
TH_3924|M.thermoresistible__bu INLSGTFDLTLSTLDNGFLTGTGFSGALRALEQSWGRD---PDTMLPDIR
MAB_4149c|M.abscessus_ATCC_199 LNVFVTFDLTARRLGETLFTTSFFDPNMQHFNDVVNPPEWLIGSMANLNG
Mb0609|M.bovis_AF2122/97 ---------------------
Rv0593|M.tuberculosis_H37Rv YTPNPNDAPGGPLVERAE---
MAV_4547|M.avium_104 YTPNPNDAPGGPLVERGE---
Mflv_0707|M.gilvum_PYR-GCK FTPNPNSAPNGPLIERSE---
Mvan_0138|M.vanbaalenii_PYR-1 FTPNPNSVPGGPLIERSE---
MSMEG_0138|M.smegmatis_MC2_155 FTPNPHDAPGGPLVERGE---
MMAR_0416|M.marinum_M YTPNPNDAPGGPLVERGDRQC
MUL_1066|M.ulcerans_Agy99 YTPNPNDAPGGPLVERGDRQC
MLBr_02593|M.leprae_Br4923 YTTNPNDAPGGPLVERADRRC
TH_3924|M.thermoresistible__bu FTPNPLDAPGGPLIERAE---
MAB_4149c|M.abscessus_ATCC_199 KETSPFDLPAPAAPQGGGR--