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M. thermoresistible (build 8) TH_3924 (-)

annotation: virulence factor Mce family protein
coordinates: 648456 - 649598
length: 381

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3924--100% (381)virulence factor Mce family protein
M. thermoresistible (build 8)TH_2780-e-13464.10% (376) PUTATIVE virulence factor Mce family protein
M. thermoresistible (build 8)TH_3267-2e-7340.33% (367) PUTATIVE virulence factor Mce family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0179lprK1e-13463.27% (373) MCE-family lipoprotein LprK
M. gilvum PYR-GCKMflv_0707-1e-13060.70% (374) virulence factor Mce family protein
M. tuberculosis H37RvRv0593lprL1e-13663.30% (376) MCE-family lipoprotein LprL
M. leprae Br4923MLBr_02593lprK1e-12056.45% (372) putative lipoprotein
M. abscessus ATCC 19977MAB_4149c-4e-5336.45% (332) MCE-family protein LprN
M. marinum MMMAR_0416lprK1e-12458.24% (376) MCE family lipoprotein LprK
M. avium 104MAV_4547-1e-12862.03% (374) virulence factor Mce family protein
M. smegmatis MC2 155MSMEG_0138-1e-13662.13% (375) virulence factor Mce family protein
M. ulcerans Agy99MUL_1066lprK1e-12357.71% (376) MCE family lipoprotein LprK
M. vanbaalenii PYR-1Mvan_0138-1e-13260.64% (376) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv0593|M.tuberculosis_H37Rv         -------MRCGVSAGSANGKPNRWTLRCGVSAGHRGSVFLLAVLLAPVVL
MAV_4547|M.avium_104                ---------MVFAAHTAGAGP---VMRRVAVAGRRALVVALAAMLT----
Mflv_0707|M.gilvum_PYR-GCK          -------------------------MSRLGTLAKRAVALGAAALVLT---
Mvan_0138|M.vanbaalenii_PYR-1       -------------------------MGKWTRLARRTVALAAAAVVLT---
MSMEG_0138|M.smegmatis_MC2_155      -------------MRLLKGFP---KMRNWTRVGRRTAVLAAVALVLT---
MMAR_0416|M.marinum_M               MRRGVSVMGAIGKSKQSAARRGVGAMRAVSRRAWQGLALLMVALVLS---
MUL_1066|M.ulcerans_Agy99           -------MGAIGKSKQSTARRGVGAMRAVSRRAWQGLALLMVALVLS---
MLBr_02593|M.leprae_Br4923          MRR---AMSVVHTSR-------------VRHQTWRGLVMLVAALLLS---
Mb0179|M.bovis_AF2122/97            ------MMSVLARMR------------VMRHRAWQGLVLLVLALLLS---
TH_3924|M.thermoresistible__bu      -------------------------MSALRRAARLLAALSVIVALTS---
MAB_4149c|M.abscessus_ATCC_199      ----------------------------MSRNVLRAAVMGVGVAVVVS--
                                                                         ..   . :     

Rv0593|M.tuberculosis_H37Rv         TSCTWRGIANVPLPVGRGMGPDRMTIYVQMPDTLALNTNSRVRVADVWVG
MAV_4547|M.avium_104                -SCTWRGIADVPLPVGRGTGGDHMTIYVQMPDTLALNTNSRVRVADVWVG
Mflv_0707|M.gilvum_PYR-GCK          SCGSWKGIANIPLPGGPGTGSERTTIYVQMPDTLALNVNSRVRVADVYVG
Mvan_0138|M.vanbaalenii_PYR-1       SCGSWKGISNVPLPGGPGSGSERTTIYVQMPDTLALNVNSRVRVADVYVG
MSMEG_0138|M.smegmatis_MC2_155      SCGQWRGIANVPLPGGPGTESGSMTLYVQMPETLALNANSRVRVRDVFVG
MMAR_0416|M.marinum_M               -SCGWRGISNVAIPGAPGTGKGSYTVYVQVPDTLAINGNSKVMVADVPVG
MUL_1066|M.ulcerans_Agy99           -SCGWRGISNVAIPGAPGTGKGSYTVYVQVPDTLAINGNSKVMVADVPVG
MLBr_02593|M.leprae_Br4923          -SCGWRGISNVSIPGGPGSGKGAYTIYVQVPDTLAINGNSKVMVADVTVG
Mb0179|M.bovis_AF2122/97            -SCGWRGISNVAIPGGPGTGPGSYTIYVQMPDTLAINGNSRVMVADVWVG
TH_3924|M.thermoresistible__bu      -CGSWRGIANVPLPSGPGTGPGSYTVYVQVEDALALNVNSRVRVADVYVG
MAB_4149c|M.abscessus_ATCC_199      -GCQFNGLNSLNLPGTAGHGSRSYTVTVELPDVTTLPQNSPVMVDDVTVG
                                        :.*: .: :*   *      *: *:: :. ::  ** * * ** **

Rv0593|M.tuberculosis_H37Rv         TVRDISLRN-----WIATLTLELEPTVRLPANATAKIGQTSLLGTQHVEL
MAV_4547|M.avium_104                TVRAITLKD-----WVATLRLDLDPGVRLPANATAKIGQTSLLGTQHVEL
Mflv_0707|M.gilvum_PYR-GCK          RVRAIELRN-----WVATLTLDLEPNIALPVNTQAKIGQTSLLGSQHVQL
Mvan_0138|M.vanbaalenii_PYR-1       RVRAIELKN-----WIATLTLDLEPSVQLPVNTLARIGQTSLLGSQHVQL
MSMEG_0138|M.smegmatis_MC2_155      RVRKIELIN-----WVPTLTVDVEPGIKLPKNTLAKIGQTSLLGSQHVEL
MMAR_0416|M.marinum_M               SIRNIQLKN-----WVATLTLGIDQGVKLPKNALAKIGQTSLLGSQHVEL
MUL_1066|M.ulcerans_Agy99           SIRNIQLKN-----WVATLTLGIDQGVKLPKNALAKIGQTSLLGSQHVEL
MLBr_02593|M.leprae_Br4923          SIRAINLKN-----WVATLTLGLNKDVQLPKNTTAKIGQTSLLGSQHVEL
Mb0179|M.bovis_AF2122/97            SIRAIKLKN-----WVATLTLSLKKDVTLPKNATAKIGQTSLLGSQHVEL
TH_3924|M.thermoresistible__bu      TVRSIDLVD-----WVGTLTISLDPAVRLPRNATAKIGQTSLLGTQHVEL
MAB_4149c|M.abscessus_ATCC_199      SVSGIDAFQKPDGSWYAGVKVSLEPEVHLPANAVAKVAQTSLLGSQHIEL
                                     :  *   :     *   : : :.  : ** *: *::.******:**::*

Rv0593|M.tuberculosis_H37Rv         AAPP-IPSPQPLKSGDTIGLKNSSAYPTVERTLASVALILTGGGIVNLDV
MAV_4547|M.avium_104                AAPK-NPSVQRLKSGDTILLQNSSAYPTVERTLASVAVILNGGGIANLDA
Mflv_0707|M.gilvum_PYR-GCK          DLPP-DPSPQRLESGDTITLENASAFPTTERVLASIASILTGGGVANLET
Mvan_0138|M.vanbaalenii_PYR-1       DLPP-DPSPQKLKSGDVIPLANASAFPTTERVLASISSILTGGGVANLET
MSMEG_0138|M.smegmatis_MC2_155      NPPE-DPSSELLRDGDTIPLAQSSAYPTIERTLAGISGILTGGGIPNIEV
MMAR_0416|M.marinum_M               AAPP-NPSSQLLKNGDTIPLKNSSAYPNTEQTLASISLILRGGGIPNLEV
MUL_1066|M.ulcerans_Agy99           AAPP-NPSSQLLKNGDTIPLKNSSAYPNTEQTLASISLILRGGGIPNLEV
MLBr_02593|M.leprae_Br4923          AAPA-NPSLELLKNGDTIPLKNSSVFPTTEQTLASLSLILRGGGIPNLET
Mb0179|M.bovis_AF2122/97            AAPP-DPSPVPLKDGDTIPLKRSSAYPTTEQTLASIATLLRGGGLVNLEG
TH_3924|M.thermoresistible__bu      AAPA-EPAPEPLRDGDTIPLRHTSAFPTTERTLAGIATVLRGGGVGNLEY
MAB_4149c|M.abscessus_ATCC_199      AAPVGEPAVGKLTGGATIPLSRTGKYPSTEEVLSALSVVVNKGNLGALQD
                                      *   *:   * .* .* * .:. :*. *..*:.:: ::  *.:  :: 

Rv0593|M.tuberculosis_H37Rv         IQTEILNILDGHAGQIREFLERLATFTAELNNQRGDLTRAIDSTNQLLTI
MAV_4547|M.avium_104                IQTEVLNILDGHAGQIREFLGRLDTFVTELSRQRDDLTRAIDSSNELLTV
Mflv_0707|M.gilvum_PYR-GCK          IQSEVYNVLNGRADQIRDFLNQLDTFTAELNQQRDDITRAIDSTNRLLTI
Mvan_0138|M.vanbaalenii_PYR-1       IQTEIYNVLNGRADQIREFLGRLDTFTEELNRQRDDITRAIDSTNRLLAI
MSMEG_0138|M.smegmatis_MC2_155      IQTEVFNILNGRADQIREFLNQLDTFTDELNQQREEITRAIDSTNRLLNI
MMAR_0416|M.marinum_M               LQNEVYDIFHGRGDQIRGFLTRLDTFTRQLNEQRDDITHAIDSTNRLMAY
MUL_1066|M.ulcerans_Agy99           LQNEVYDIFHGRGDQIRGFLTRLDTFTRQLNEQRDDITHAIDSTNRLMAY
MLBr_02593|M.leprae_Br4923          LTNEVFNIFHGRADQIHAFLTKLDTFASQLNQQRDDITHAIDSTNRLLTY
Mb0179|M.bovis_AF2122/97            IQQEINAIVTGRADQIRAFLGKLDTFTDELNQQRDDITRAIDSTNRLLAY
TH_3924|M.thermoresistible__bu      LQNEVHAMLSGNAEQIGEFLDRLAVFTASLNDQIDQIDRAISSTRRLAGV
MAB_4149c|M.abscessus_ATCC_199      ITDETYNLFKGRTGNLTQVLPKLATLISSLNSQRDDIISAIEGIDKFSRV
                                    :  *   :. *.  ::  .* :* .:  .*. *  ::  **..  .:   

Rv0593|M.tuberculosis_H37Rv         IANRNDTLDRVLTDVPPLIEHFADTGQLFADATESLGRFSEVANRALAAT
MAV_4547|M.avium_104                FANRRDTLDRVLTELPPLIRHFADTRELFADATESLGRFSDAADRALTDT
Mflv_0707|M.gilvum_PYR-GCK          VAQRNETLDAVLTEFPPLIKHFADTRDLFGDAIESLGRISNAAVAALEPA
Mvan_0138|M.vanbaalenii_PYR-1       VGQRNQTLDAVLTEFPPLIQHFADTRDLFADAVESLGRISNAAVDALAPA
MSMEG_0138|M.smegmatis_MC2_155      VSQRNDTLDRVLTEFPPLIQHFAETRDLFADAVTALGRLSAAADETLSGS
MMAR_0416|M.marinum_M               VGGRADVVDRALTDLPPLIKHFADTRDLLINAVNSVGQLSDVTGRYLSEA
MUL_1066|M.ulcerans_Agy99           VGGRADVVDRALTDLPPLIKHFADTRDLLINAVNSVGQLSDVTGRYLSEA
MLBr_02593|M.leprae_Br4923          VGGRSDVLDQILTDIPPLIKHFADTKNLLINAVGSVGQLSQAVDQYLSEA
Mb0179|M.bovis_AF2122/97            VGGRSEVLNRVLTDLPPLIKHFADKQELLINASDAVGRLSQSADQYLSAA
TH_3924|M.thermoresistible__bu      VAERSATLERVLTEVPPLIEHFAAQRELFVDGMEALGRFAHITDEALTAA
MAB_4149c|M.abscessus_ATCC_199      LAEHKESLGRAIDSIEPALKVLNENRANIIEAFRSVGNLAKITDRVLRTT
                                    .. :   :   : .. * :. :      : :.  ::*.::  .   *  :

Rv0593|M.tuberculosis_H37Rv         RPNLHQTLQSLQRPLRQLERASPYVVGALKLGLTAPFNIDEVPNVIRGDY
MAV_4547|M.avium_104                RANLYRSLLSLQRPLRQLVPAAPFVAGALKLGLTAPFNIDDVAQVIRGDY
Mflv_0707|M.gilvum_PYR-GCK          NGDMNQNLQNLQRPLRELGKSGPYLLGALKIFLTAPYSIENLPKAIRGDY
Mvan_0138|M.vanbaalenii_PYR-1       SDDINTNLANLQRPLRELGKSGPYLLGALKIFLTAPYNIENVPKAIRGDY
MSMEG_0138|M.smegmatis_MC2_155      NANLHTNLQNLQRPLKQLGRAAPYLVGALKLILTVPFNIDNIPKAIRGDY
MMAR_0416|M.marinum_M               RGNLHTDLQSLQCPLKELGRGSQYLIGALKLILTQPFDIDAVPKIFRGDY
MUL_1066|M.ulcerans_Agy99           RGNLHTDLQSLQCPLKELGRGSQYLIGALKLILTQPFDIDAVPKIFRGDY
MLBr_02593|M.leprae_Br4923          RGPLHTDLQALACPLRELGRGAPYFIGAMKLILTQPYDVDTVPKIMRGDY
Mb0179|M.bovis_AF2122/97            RGDLHQDLQALQCPLKELRRAAPYLVGALKLILTQPFDVDTVPQLVRGDY
TH_3924|M.thermoresistible__bu      RADLHTNLRLLQRPLRELARAAPYLPEALQLLLTLPFTIDNVDKVVRGDY
MAB_4149c|M.abscessus_ATCC_199      KDDIVADLKGLYPVVRALAENRDVLIDSLDLLPTFPFSTKYLRNAVRGDY
                                       :   *  *   :: *      .  ::.:  * *:  . : : .****

Rv0593|M.tuberculosis_H37Rv         VNVSATFDVTLSALDNALLSGTGISGMLRALEQAWGRDPDTMIPDVR---
MAV_4547|M.avium_104                VNVSAALDLTLSTIDNTMLTGTGLSGALRALEQSWGRDPATMIPDVR---
Mflv_0707|M.gilvum_PYR-GCK          VNVSLTVDLTLSAIDNGFFSGTGISGMLRALEQAWGRDPATMIPDVR---
Mvan_0138|M.vanbaalenii_PYR-1       INVSLTVDLTLSAIDNGFFSGTGISGMLRALEQAWGRDPATMIPDVR---
MSMEG_0138|M.smegmatis_MC2_155      INVSLKLDLTLSSVDNAFLSGTGVSGMLRALEQAWGRDPATMIPDVR---
MMAR_0416|M.marinum_M               QNVSATLDVTFSAMDNAVLTGTGFSGALRALEQSFGRDPETMIPDVR---
MUL_1066|M.ulcerans_Agy99           QNVSAALDVTFSAMDNAVLTGTGFSGALRALEQSFGLDPETMIPDVR---
MLBr_02593|M.leprae_Br4923          QNVSLTLDVTYSAMDNAVLTGTGLSGALRALEQSFGRDPETMIPDVR---
Mb0179|M.bovis_AF2122/97            MNLSLTLDLTYSAIDNAFLTGTGFSGALRALEQSFGRDPETMIPDIR---
TH_3924|M.thermoresistible__bu      INLSGTFDLTLSTLDNGFLTGTGFSGALRALEQSWGRDPDTMLPDIR---
MAB_4149c|M.abscessus_ATCC_199      LNVFVTFDLTARRLGETLFTTSFFDPNMQHFNDVVN-PPEWLIGSMANLN
                                     *:   .*:*   :.: .:: : ..  :: :::  .  *  :: .:    

Rv0593|M.tuberculosis_H37Rv         -YTPNPNDAPGGPLVERAE---
MAV_4547|M.avium_104                -YTPNPNDAPGGPLVERGE---
Mflv_0707|M.gilvum_PYR-GCK          -FTPNPNSAPNGPLIERSE---
Mvan_0138|M.vanbaalenii_PYR-1       -FTPNPNSVPGGPLIERSE---
MSMEG_0138|M.smegmatis_MC2_155      -FTPNPHDAPGGPLVERGE---
MMAR_0416|M.marinum_M               -YTPNPNDAPGGPLVERGDRQC
MUL_1066|M.ulcerans_Agy99           -YTPNPNDAPGGPLVERGDRQC
MLBr_02593|M.leprae_Br4923          -YTTNPNDAPGGPLVERADRRC
Mb0179|M.bovis_AF2122/97            -YTPNPNDAPGGPLVERGNRQC
TH_3924|M.thermoresistible__bu      -FTPNPLDAPGGPLIERAE---
MAB_4149c|M.abscessus_ATCC_199      GKETSPFDLPAPAAPQGGGR--
                                       ..* . *  .  : .