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SSPSKLRVIQWASGGVGKAAIQCVLNHPRLELAGCWVHSAEKNGVDVGRIIGTQELGVTASTSVDEVLAL DADCVVYSPLIPNDDEVIAILRSGKNVVTPVGWVYPDPGNPRHRAVADAALESGVTLHGSGIHPGGITER FPLMVSSLSSAVTHVRAEEFSDIRTYNAPDVVRHIMGFGGTPEEATGGPMAGLLDGGFKQSVRMIADHMG FRIDPNIRTIQDVAVATADIDYDPFPITAGTVAARRFRWQALVDGEPVITAAVNWLMGEQNLDPAWDFGG RGERFEVEITGDPDVSLTFKGLQPETIAEGLVKNPGVVVTANHCVNAIPDVCAAAPGIKTYLDLPLFAGR PAPGLATS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0353 | - | - | 100% (359) | hypothetical protein MAV_0353 |
| M. avium 104 | MAV_0371 | dapB | 3e-52 | 36.00% (350) | dihydrodipicolinate reductase |
| M. avium 104 | MAV_1757 | dapB | 6e-45 | 33.15% (356) | dihydrodipicolinate reductase N-terminus domain-containing |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1088 | - | 1e-124 | 60.80% (352) | hypothetical protein Mb1088 |
| M. gilvum PYR-GCK | Mflv_2027 | - | 1e-121 | 59.21% (353) | dihydrodipicolinate reductase |
| M. tuberculosis H37Rv | Rv1059 | - | 1e-124 | 60.80% (352) | hypothetical protein Rv1059 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4633 | - | 6e-41 | 32.40% (358) | hypothetical protein MAB_4633 |
| M. marinum M | MMAR_5280 | - | 1e-161 | 77.05% (353) | hypothetical protein MMAR_5280 |
| M. smegmatis MC2 155 | MSMEG_5286 | dapB | 1e-118 | 59.09% (352) | dihydrodipicolinate reductase N-terminus domain-containing |
| M. thermoresistible (build 8) | TH_1493 | - | 1e-121 | 59.31% (349) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4353 | - | 1e-154 | 74.22% (353) | hypothetical protein MUL_4353 |
| M. vanbaalenii PYR-1 | Mvan_4692 | - | 1e-123 | 60.68% (351) | dihydrodipicolinate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5280|M.marinum_M MSGPAKLRVIQWATGGVGKAAIECILNHPQLELAGCWVHSAAKHGLDVGT
MUL_4353|M.ulcerans_Agy99 MSGPAKLRVIQWATGGVGKAAIECILNHPQLELAGCWVHSAAKHGLDVGT
MAV_0353|M.avium_104 MSSPSKLRVIQWASGGVGKAAIQCVLNHPRLELAGCWVHSAEKNGVDVGR
Mflv_2027|M.gilvum_PYR-GCK ----MALRVVQWATGGVGIAAIHGVLAHPELELVGCWVHSKAKAGRDVGD
Mvan_4692|M.vanbaalenii_PYR-1 ----MTLRVVQWATGGVGVAAIKGVLEHPELELVGCWVHSPGKAGRDVGE
MSMEG_5286|M.smegmatis_MC2_155 ----MALRVVQWATGGVGMAAIKGVLEHPALELVGCWVHSEGKAGRDVGE
TH_1493|M.thermoresistible__bu ----MTFRVVQWATGGVGIAAIKGVLEHPELELVGCWVHSPDKAGRDVGE
Mb1088|M.bovis_AF2122/97 --MTMSLRVIQWATGSVGVAAIKGVLQHPELELVGCWVHSAAKSGKDVGE
Rv1059|M.tuberculosis_H37Rv --MTMSLRVIQWATGSVGVAAIKGVLQHPELELVGCWVHSAAKSGKDVGE
MAB_4633|M.abscessus_ATCC_1997 ---MTKTRVAVWGTGNVGQHALAGVITDPSMELVGVWVSGSNKAGKDAGA
** *.:*.** *: :: .* :**.* ** . * * *.*
MMAR_5280|M.marinum_M IIGAARLG-VTATNDVDELLALDADCVMYSPLVAD-----EQDVKAILRS
MUL_4353|M.ulcerans_Agy99 IIGAARFG-VTATNDVDELLALDADCVMYSPQVAD-----EQDVKAILRS
MAV_0353|M.avium_104 IIGTQELG-VTASTSVDEVLALDADCVVYSPLIPN-----DDEVIAILRS
Mflv_2027|M.gilvum_PYR-GCK IVGTAPLG-VVATDSIDEILSLDADAVIYSPLIAD-----TEEVVALLKS
Mvan_4692|M.vanbaalenii_PYR-1 IVGLDPLG-VTATDSIDDILALEADAVIYSPLIAN-----PDEVAALLRS
MSMEG_5286|M.smegmatis_MC2_155 IIGTEPLG-VETTRDIDDILGLDADAVIYAPLLPN-----PEEVAALLRS
TH_1493|M.thermoresistible__bu IIGAEPLG-ITATNSIDDILALDADAVIYAPLLPD-----PDEVAALLRS
Mb1088|M.bovis_AF2122/97 IIGSPPLG-VIATNSIDDVLALDADAVIYAPLLPS-----VDEVAALLRS
Rv1059|M.tuberculosis_H37Rv IIGSPPLG-VIATNSIDDVLALDADAVIYAPLLPS-----VDEVAALLRS
MAB_4633|M.abscessus_ATCC_1997 LAGLDILTGITATTDAAQILALRPDCVVYTAMTDNRLMEALKDLTDLLSA
: * : : :: . ::*.* .*.*:*:. . .:: :* :
MMAR_5280|M.marinum_M GKNVVT--PVGWVYPD--LSKPRVKAVADAAVAGGVTLHGSGIHPGGITE
MUL_4353|M.ulcerans_Agy99 GKNVFT--PVGWVYPD--LSKPRVKAVADAAVAGGVTLHGSGIHPGGITE
MAV_0353|M.avium_104 GKNVVT--PVGWVYPD--PGNPRHRAVADAALESGVTLHGSGIHPGGITE
Mflv_2027|M.gilvum_PYR-GCK GKNVVT--PVGWLYP----SERSGAPLREAALAGDATLHGTGIAPGGISE
Mvan_4692|M.vanbaalenii_PYR-1 GKNVVT--PVGWLYP----SERSGASMREAALAGNATLHGTGIAPGGISE
MSMEG_5286|M.smegmatis_MC2_155 GKNVVT--PVGWVYP----SERQGAPLREAALAGNATLHGTGIAPGGISE
TH_1493|M.thermoresistible__bu GKNVVT--PLGWFYP----TEKQAAPLRAAALEGGATLHGTGIAPGGISE
Mb1088|M.bovis_AF2122/97 GKNVVT--PLGWFYP----SEKEAAPLEVAAQAGNATLHGAGIGPGAVTE
Rv1059|M.tuberculosis_H37Rv GKNVVT--PLGWFYP----SEKEAAPLEVAAQAGNATLHGAGIGPGAVTE
MAB_4633|M.abscessus_ATCC_1997 GINVAASAPVFLQYPWGVLPENMLTPIENAAREGNSSIFAGGIDPGFAND
* ** : *: ** : .: ** .. ::.. ** ** .:
MMAR_5280|M.marinum_M RFPLMVSSLSSAITHVRAEEFSDIRTYNAPDVVRDIMGFGVPPAQAMQGP
MUL_4353|M.ulcerans_Agy99 RFPLMVSSLSSAITHVRAEEFSDIRTYNAPDVVRDIMGFGVPHAQAMQGP
MAV_0353|M.avium_104 RFPLMVSSLSSAVTHVRAEEFSDIRTYNAPDVVRHIMGFGGTPEEATGGP
Mflv_2027|M.gilvum_PYR-GCK KFPLMLSAMSTGVTFVRAEEYSDLRTYEAPDVLRHVMGFGETPDKALTGP
Mvan_4692|M.vanbaalenii_PYR-1 KFPLMLSAMSTGVTFVRAEEFSDLRTYEAPDVLRHVMGFGETPDKALTGP
MSMEG_5286|M.smegmatis_MC2_155 KFPLLFSVFSTGVTFVRAEEFSDLRTYDAPDVLRHVMGFGEVPDKALSGP
TH_1493|M.thermoresistible__bu KLPLMFSALATGVTFVRAEEFSDLRTYDAPDVVRHVMGFGDTPEKALSGP
Mb1088|M.bovis_AF2122/97 LFPLLLSVMSTGVTFVRSEEFSDLRSYGAPDVLRYVMGFGGTPDSALTGP
Rv1059|M.tuberculosis_H37Rv LFPLLLSVMSTGVTFVRSEEFSDLRSYGAPDVLRYVMGFGGTPDSALTGP
MAB_4633|M.abscessus_ATCC_1997 LLPLALMGTCQRIDQVRCIEIVDYATYDSATVMFDVMGFGKPMEETPMLL
:** . . : **. * * :* :. *: :**** .:
MMAR_5280|M.marinum_M MAALLESGFKMSVRMIADHMGFHIDPTIRATHEIAVATSDIASDVLPIAA
MUL_4353|M.ulcerans_Agy99 MAALLESGFKMSVRMIANHMGFHIDPMIRATHEIAVATSDIASDVLPIAA
MAV_0353|M.avium_104 MAGLLDGGFKQSVRMIADHMGFRIDPNIRTIQDVAVATADIDYDPFPITA
Mflv_2027|M.gilvum_PYR-GCK MQKMLDSGFIQAVRMVVDQLGFAADPKVRATQEIAVATAPIDSPMGQILP
Mvan_4692|M.vanbaalenii_PYR-1 MQKMLDTGFIQAVRMCVDQLGFAADPKVLATQEIAVATARIDSPMGPIEP
MSMEG_5286|M.smegmatis_MC2_155 MQKLLDGGFMQAVKMCVDQFGFAADPKIRSRQEIAVATAPIDSPLGAIQP
TH_1493|M.thermoresistible__bu MQKLLDGGFIQAVRMCVDKIGFAADPQVRSRQEIAVATAPIESPIGVIEP
Mb1088|M.bovis_AF2122/97 MQKILDGGFLQSVRLCVDRLGFAADPQIRTSQEVAVATAPIDSPIGVIEP
Rv1059|M.tuberculosis_H37Rv MQKILDGGFLQSVRLCVDRLGFAADPQIRTSQEVAVATAPIDSPIGVIEP
MAB_4633|M.abscessus_ATCC_1997 QPGVLSLAWGSVVRQLAAGLGVELD-EVTEVYEKLSAPEDFDISSGHIPA
:*. .: *: . :*. * : : *. : * .
MMAR_5280|M.marinum_M GTVAGRKFRWQALADGKPVITAAVNWLMGQADMDPDWSFGE-RGERFEIE
MUL_4353|M.ulcerans_Agy99 DTVAGRKFRWQTLADGKPVITAAVNWLMGQADMHPDWSFGE-RGERFEIE
MAV_0353|M.avium_104 GTVAARRFRWQALVDGEPVITAAVNWLMGEQNLDPAWDFGG-RGERFEVE
Mflv_2027|M.gilvum_PYR-GCK GQVAGRKFHWEALVGGQPVVRVTVNWLMGEENLEPAWSFGP-EGQRYEME
Mvan_4692|M.vanbaalenii_PYR-1 GQVAGRKFHWEALVDGEPVVRVTVNWLMGEENLDPAWSFGP-EGQRYEME
MSMEG_5286|M.smegmatis_MC2_155 GQVAGRRFHWEALRGEQVVVRVTVNWLMGEENLDPPWTFGP-QGQRYEMQ
TH_1493|M.thermoresistible__bu GQVAGRRFHWEALAGDEVVVRVTVNWLMGEEDLDPPWDFGP-AGQRYEIE
Mb1088|M.bovis_AF2122/97 GQVAGRRFHWEALVEDTVVVQIAVNWLMGSENLDPPWSFGP-AGERYEIE
Rv1059|M.tuberculosis_H37Rv GQVAGRRFHWEALVEDTVVVQIAVNWLMGSENLDPPWSFGP-AGERYEIE
MAB_4633|M.abscessus_ATCC_1997 GTMAALHFEVRGIKDGR-AVTVLEHFTRLREDLAPNWPQPAHEGGTYRVE
. :*. :*. . : .: :: :: * * * :.::
MMAR_5280|M.marinum_M VTGDPSVSLVFKGLQPTSIAEGLQRNPGVVATANHCVNAIPVVCAADPGI
MUL_4353|M.ulcerans_Agy99 ITGNPSVSLVFKGLQPTSITEGLQRNPGVVATANHCANAIPVVCAADPGI
MAV_0353|M.avium_104 ITGDPDVSLTFKGLQPETIAEGLVKNPGVVVTANHCVNAIPDVCAAAPGI
Mflv_2027|M.gilvum_PYR-GCK VRGNPDFTVSVKGFQSDIGGEGPE--YGVVGTAAHCVNSVPAVCAAAPGI
Mvan_4692|M.vanbaalenii_PYR-1 VRGNPDFTVSVKGFQSEVGGEGPE--YGVVGTAAHCVNSVPAVCAAPPGI
MSMEG_5286|M.smegmatis_MC2_155 VCGNPDFDVVIKGFQGEVGETGPE--PGVVATAAHCVNSIPAVCAAEPGI
TH_1493|M.thermoresistible__bu VRGNPDFTVTINGFQSEPGDHGPE--AGIVATAAHCVNSVPAVCAADPGL
Mb1088|M.bovis_AF2122/97 VRGSPDTCVTIKGWQPQTVAAGLKSNPGIVATAAHCVNAIPATCAAPAGI
Rv1059|M.tuberculosis_H37Rv VRGSPDTCVTIKGWQPQTVAAGLKSNPGIVATAAHCVNAIPATCAAPAGI
MAB_4633|M.abscessus_ATCC_1997 ITGEPSYLLDLGSFS----ARGDHNYANLIATAMRVVNAVPAVVAAEAGI
: *.*. : . . . * .:: ** : .*::* . ** .*:
MMAR_5280|M.marinum_M ATYLDLPLFAGRPARASRGLER
MUL_4353|M.ulcerans_Agy99 ATYLDLPLFAGRPARASRGLER
MAV_0353|M.avium_104 KTYLDLPLFAGRPAPGLATS--
Mflv_2027|M.gilvum_PYR-GCK ATYLDLPLISGKAAPDRARTGS
Mvan_4692|M.vanbaalenii_PYR-1 ATYLDLPLISGKAAPAKARAGI
MSMEG_5286|M.smegmatis_MC2_155 ATYLDLPLFSAKAAPHLR----
TH_1493|M.thermoresistible__bu LTYLDMPLISGRAAPRLT----
Mb1088|M.bovis_AF2122/97 QSFFDLPLITGRAAPGLAR---
Rv1059|M.tuberculosis_H37Rv QSFFDLPLITGRAAPGLAR---
MAB_4633|M.abscessus_ATCC_1997 RTTLDLPLITGKGRAV------
: :*:**::.: