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MNAVNTHIARRAGIPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSVGAPEPIRAAAAAALHLNELGYTVA LGIPELRAAIAADYHRQHGISVEPEAVVITTGSSGGFLLTFLACFDVGDRVALASPGYPCYRNILSALGC EVVEIPCGPETRFQPTADMLAQIDPPVQGVIVASPANPTGTVIPPEELAAIASWCDASGARLISDEVYHG LVYEGAPPTSCARQTSRNALVVNSFSKYYAMTGWRLGWLLVPTELRRAVDCLTGNFTICPPVLSQVAAVS AFTPEATKEADDNLRHYASNRSTLLDGLRRIGIDRLAPTDGAFYVYADVSDFTDDSFKFCSKLLADTGVA IAPGIDFDTAGGNSFVRLSFAGPSEDIREALRRIESWLPER
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4130 | aspB | - | 100% (391) | aspartate aminotransferase |
| M. ulcerans Agy99 | MUL_0297 | - | 6e-30 | 29.35% (368) | aminotransferase |
| M. ulcerans Agy99 | MUL_1026 | - | 1e-22 | 26.19% (378) | N-succinyldiaminopimelate aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3595 | aspB | 0.0 | 87.37% (388) | aspartate aminotransferase |
| M. gilvum PYR-GCK | Mflv_1476 | - | 1e-179 | 79.00% (381) | aspartate aminotransferase |
| M. tuberculosis H37Rv | Rv3565 | aspB | 0.0 | 87.37% (388) | aspartate aminotransferase |
| M. leprae Br4923 | MLBr_02502 | - | 3e-19 | 26.58% (380) | aminotransferase AlaT |
| M. abscessus ATCC 19977 | MAB_0685 | - | 1e-126 | 59.06% (381) | aspartate aminotransferase |
| M. marinum M | MMAR_5054 | aspB | 0.0 | 98.98% (391) | aspartate aminotransferase AspB |
| M. avium 104 | MAV_0596 | - | 0.0 | 85.82% (388) | aspartate aminotransferase |
| M. smegmatis MC2 155 | MSMEG_6017 | - | 0.0 | 79.48% (385) | aspartate aminotransferase |
| M. thermoresistible (build 8) | TH_2065 | aspB | 1e-176 | 78.44% (385) | POSSIBLE ASPARTATE AMINOTRANSFERASE ASPB (TRANSAMINASE A) |
| M. vanbaalenii PYR-1 | Mvan_5290 | - | 1e-176 | 77.43% (381) | aspartate aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4130|M.ulcerans_Agy99 ---MNAVNTHIARRAGIPPFYVMDVWLAAAERQRTHG-------------
MMAR_5054|M.marinum_M ---MNAVNTHIARRAGIPPFYVMDVWLAAAERQRTHG-------------
Mb3595|M.bovis_AF2122/97 ------MTDRVALRAGVPPFYVMDVWLAAAERQRTHG-------------
Rv3565|M.tuberculosis_H37Rv ------MTDRVALRAGVPPFYVMDVWLAAAERQRTHG-------------
MAV_0596|M.avium_104 ------MTDRVSLRAGIPPFYVMDVWLAAAERQRSHG-------------
Mflv_1476|M.gilvum_PYR-GCK --------MTPSQRSGIPPFYVMDVWLAAAERQRTHG-------------
Mvan_5290|M.vanbaalenii_PYR-1 --------MTVSQRSGIPPFYVMDVWLAAAERRRTHG-------------
TH_2065|M.thermoresistible__bu ------MNDRTALRAGIPPFYVMDVWLAAAERQRSHG-------------
MSMEG_6017|M.smegmatis_MC2_155 ---MGEMNDRVALRAGVPPFYVMDVWQAAAERQRTHG-------------
MAB_0685|M.abscessus_ATCC_1997 -------MVDLSRRSDVPPFYVMDVLAAAATRQRTHG-------------
MLBr_02502|M.leprae_Br4923 MTLYQQISVDGSGTMSDVTTHQLPMHTPGYHRQRAFAQSSKLQDVLYEIR
: . . : : : .. *:*:..
MUL_4130|M.ulcerans_Agy99 ---------------DLVNLSAGQPSVG---APEPIRAAAAAALHLNELG
MMAR_5054|M.marinum_M ---------------DLVNLSAGQPSVG---APEPIRAAAAAALHLNELG
Mb3595|M.bovis_AF2122/97 ---------------DLVNLSAGQPSAG---APEPVRAAAAAALHLNQLG
Rv3565|M.tuberculosis_H37Rv ---------------DLVNLSAGQPSAG---APEPVRAAAAAALHLNQLG
MAV_0596|M.avium_104 ---------------DLVNLSAGQPSVG---APEPVRAAAAAAVHSNELG
Mflv_1476|M.gilvum_PYR-GCK ---------------DLVNLSAGQPSAG---APTAVRDAAVAALHRNQLG
Mvan_5290|M.vanbaalenii_PYR-1 ---------------DLVNLSAGQPSAG---APSAVRDAAVAALNRNDLG
TH_2065|M.thermoresistible__bu ---------------DLVNLSAGQPSAG---APAPVRAAAAATLERNQLG
MSMEG_6017|M.smegmatis_MC2_155 ---------------DLVNLSAGQPSAG---APAPVRDAAAAALGRNQLG
MAB_0685|M.abscessus_ATCC_1997 ---------------DMISLAAGQPSTG---APAVVLDAVREALGTQVLG
MLBr_02502|M.leprae_Br4923 GPVSQHATRLETEGHRILKLNIGNPALFGFDAPDVIMRDMIQALP-YAQG
::.* *:*: ** : :: *
MUL_4130|M.ulcerans_Agy99 YTVALGIPELRAAIAADYHRQHGIS-VEPEAVVITTGSSGGFLLTFLACF
MMAR_5054|M.marinum_M YTVALGIPELRAAIAADYHRQHGIS-VEPEAVVITTGSSGGFLLTFLACF
Mb3595|M.bovis_AF2122/97 YSVALGIPELRDAIAADYQRRHGIT-VEPDAVVITTGSSGGFLLAFLACF
Rv3565|M.tuberculosis_H37Rv YSVALGIPELRDAIAADYQRRHGIT-VEPDAVVITTGSSGGFLLAFLACF
MAV_0596|M.avium_104 YSVSLGTPELRAAIAADYRRQHGLE-VEPDAVVITTGSSGGFLLTFLACF
Mflv_1476|M.gilvum_PYR-GCK YTVALGIPELRTAIAGSYQDRHGLE-VDPGDVVITTGSSGGFLLAFLACF
Mvan_5290|M.vanbaalenii_PYR-1 YTVALGIPELRAAIAGSYTARHGLT-VDPDDVVVTTGSSGGFLLTFLACF
TH_2065|M.thermoresistible__bu YTVALGIPELREAIAAGYQSRYGLS-VGADEVVITTGSSGGFLLAFLACF
MSMEG_6017|M.smegmatis_MC2_155 YTVALGIPELREQIAQTYHTRHDID-VGVDDVVLTTGSSGGFLLTFLACF
MAB_0685|M.abscessus_ATCC_1997 YTETLGLPELRSAIAAYHRERSDIA-VTADDVVVTTGSSGGFTLLFLAAF
MLBr_02502|M.leprae_Br4923 YSDSQGILPARRAVVTRYELVDGFPRFDVDDVYLGNGVSELITMTLQALL
*: : * * :. : .: . * : .* * : : : * :
MUL_4130|M.ulcerans_Agy99 DVGDRVALASPGYPCYRNILSALGCEVVEIPCGPETRFQPTADMLAQIDP
MMAR_5054|M.marinum_M DVGDRVALASPGYPCYRNILSALGCEVVEIPCGPETRFQPTADMLAQIDP
Mb3595|M.bovis_AF2122/97 DAGDRVAMASPGYPCYRNILSALGCEVVEIPCGPQTRFQPTAQMLAEIDP
Rv3565|M.tuberculosis_H37Rv DAGDRVAMASPGYPCYRNILSALGCEVVEIPCGPQTRFQPTAQMLAEIDP
MAV_0596|M.avium_104 DVGDRVAVASPGYPCYRNILSALGCEVVEIPCGPQTRFQPTAAMLAELDP
Mflv_1476|M.gilvum_PYR-GCK DVGDRVAIASPGYPCYRNILSALGCEVVELPCGPDTRFQPTLQMLTELDP
Mvan_5290|M.vanbaalenii_PYR-1 DPGDRVAIASPGYPCYRNILTALGCEVVELPCGPKTRFQPTLQMLTELDP
TH_2065|M.thermoresistible__bu DVGDRVAIASPGYPCYRNILSALGCEVVELQCGPQTRFQPTARMLAELDP
MSMEG_6017|M.smegmatis_MC2_155 DVGDRVAITSPGYPCYRNILSALGCEVVEIPCGPETRFQPTAAMLEALDP
MAB_0685|M.abscessus_ATCC_1997 DVGDTVVMTRPGYPAYRNCLAALGCRVVELDCGPETRYQPTVAMLEALAQ
MLBr_02502|M.leprae_Br4923 DNGDQVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQPDIADVESKIT
* ** * :. *.** : : * *. *. :** :
MUL_4130|M.ulcerans_Agy99 P----VQGVIVASPANPTGTVIPPEELAAIASWCDASGARLISDEVYHGL
MMAR_5054|M.marinum_M P----VQGVIVASPANPTGTVIPPEELAAIASWCDASGARLISDEVYHGL
Mb3595|M.bovis_AF2122/97 P----LRGVVVASPANPTGTVIPPEELAAIASWCDASDVRLISDEVYHGL
Rv3565|M.tuberculosis_H37Rv P----LRGVVVASPANPTGTVIPPEELAAIASWCDASDVRLISDEVYHGL
MAV_0596|M.avium_104 P----VQGVIVASPANPTGTVIAPEELAAIASWCEASGARLVSDEVYHGL
Mflv_1476|M.gilvum_PYR-GCK P----VSGVIVASPANPTGTVIAPEELAAIAAWCETSGVRLISDEVYHGL
Mvan_5290|M.vanbaalenii_PYR-1 P----VSGVIVASPANPSGTVIPPAELAAIATWCESSGVRLISDEVYHGL
TH_2065|M.thermoresistible__bu P----VRGVIVASPANPTGTVIPPEELAAIARWCEDNDVRLISDEVYHGL
MSMEG_6017|M.smegmatis_MC2_155 P----VQGVIVASPANPTGTVIAPEELAAIARWCDASGARLVSDEIYHGL
MAB_0685|M.abscessus_ATCC_1997 ADGRVPAGLIVASPANPTGTIIDAGKLEAIALWCEANGTLLISDEIYHGL
MLBr_02502|M.leprae_Br4923 ER---TKALVVINPNNPTGAVYSNEILNQIVDLARKHQLLLLADEIYDKI
.::* .* **:*:: * *. . *::**:*. :
MUL_4130|M.ulcerans_Agy99 VYEGAPPTSCARQT-SRNALVVNSFSKYYAMTGWRLGWLLVPTELRRAVD
MMAR_5054|M.marinum_M VYEGAPPTSCAWQT-SRNAVVVNSFSKYYAMTGWRLGWLLVPTELRRAVD
Mb3595|M.bovis_AF2122/97 VYQGAPQTSCAWQT-SRNAVVVNSFSKYYAMTGWRLGWLLVPTVLRRAVD
Rv3565|M.tuberculosis_H37Rv VYQGAPQTSCAWQT-SRNAVVVNSFSKYYAMTGWRLGWLLVPTVLRRAVD
MAV_0596|M.avium_104 VYEGAPPTSCAWQT-SRNAVVVNSFSKYYAMTGWRLGWLLVPVELRRAVE
Mflv_1476|M.gilvum_PYR-GCK VYPGAPATSCAWET-SRESIVVNSFSKYFAMTGWRLGWLLVPDELKRAVD
Mvan_5290|M.vanbaalenii_PYR-1 VYPGAPATSCAWET-SREAVVVNSFSKYFAMTGWRLGWLLVPDELKRAVD
TH_2065|M.thermoresistible__bu VYPGAPETSCAWQT-SREAVVVNSFSKYFAMTGWRLGWLLVPPALLRAVD
MSMEG_6017|M.smegmatis_MC2_155 VYEGAPETTCAWET-SRNAVVVNSFSKYFAMTGWRLGWLLVPEKLRRAVD
MAB_0685|M.abscessus_ATCC_1997 SY-GDQKTSSAWEF-SRESVVMGSVSKYFSMTGWRLGWMLVPRRFLRAVD
MLBr_02502|M.leprae_Br4923 LYDDTKHISVASIAPDLLCLTFNGLSKAYRVAGYRSGWLAITGPKDHASS
* . : * . .:.....** : ::*:* **: :. :* .
MUL_4130|M.ulcerans_Agy99 CLT-----GNFTICPPVLSQVAAVSAFT-PEATKEADDNLRHYASNRSTL
MMAR_5054|M.marinum_M CLT-----GNFTICPPVLSQVAAVSAFT-PEATKEADGNLRHYASNRSTL
Mb3595|M.bovis_AF2122/97 CLT-----GNFTICPPVLSQIAAVSAFT-PEATAEADGNLASYAINRSLL
Rv3565|M.tuberculosis_H37Rv CLT-----GNFTICPPVLSQIAAVSAFT-PEATAEADGNLASYAINRSLL
MAV_0596|M.avium_104 CLT-----GNFTICPPVLSQLAAVAAFT-PEATAEADGHLHHYAKNRALL
Mflv_1476|M.gilvum_PYR-GCK RLT-----GNFTICPPVLPQLAAVAAFT-PESVAEAESLLEGYGANRTML
Mvan_5290|M.vanbaalenii_PYR-1 RLT-----GNFTICPPALPQIAAVSAFT-PESIAEAEALLHDYAANRTLL
TH_2065|M.thermoresistible__bu RLT-----GNFTICPPALAQVAAVEAFH-PESIAEAEALLDHYATNRRLL
MSMEG_6017|M.smegmatis_MC2_155 CLT-----GNFTICPPALAQYAALAAFT-PESLAEAEGLLTHYAENRHLL
MAB_0685|M.abscessus_ATCC_1997 RLS-----SNFTICPPAVSQYGALAAFS-PEARDELDGHVRRYAANRTLL
MLBr_02502|M.leprae_Br4923 FIGGINLLANMRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDVA
: .*: :** . .* . *: :: : :*
MUL_4130|M.ulcerans_Agy99 LDGLRRIGIDRLAPTDGAFYVYADVSDFTD---DSFKFCSKLLADTGVAI
MMAR_5054|M.marinum_M LDGLRRIGIDRLAPTDGAFYVYADVSDFTD---DSLKFCSKLLADTGVAI
Mb3595|M.bovis_AF2122/97 LDGLRRIGIDRLAPTDGAFYVYADVSDFTS---DSLAFCSKLLADTGVAI
Rv3565|M.tuberculosis_H37Rv LDGLRRIGIDRLAPTDGAFYVYADVSDFTS---DSLAFCSKLLADTGVAI
MAV_0596|M.avium_104 LDGLRGIGITRLAPTDGAFYVYADVSDFTD---NSMEFCSKLLEQTGVAI
Mflv_1476|M.gilvum_PYR-GCK LDGLRALGIDRLAPTDGAFYVYADVSHLTT---DSLSFCSKLLADTGVAI
Mvan_5290|M.vanbaalenii_PYR-1 LDGLSALGIDRLAPTDGAFYVYADVSHLTT---DSLAFCSKLLDDTGVAI
TH_2065|M.thermoresistible__bu IDGLRSLGIDRLAPADGAFYVYADVSRYTE---DSIEFCSKLLADTGVAI
MSMEG_6017|M.smegmatis_MC2_155 LNGLRGLGIDKLAPTDGAFYVYADVSKYTD---NSLQFCEKLLNDTGVAI
MAB_0685|M.abscessus_ATCC_1997 IDGLAAMGITKIAPPDGAFYAYADIEHLTD---NAEQWCADLLARTGVAV
MLBr_02502|M.leprae_Br4923 WTKLNEIPGVSCVKPTGALYAFPRLDPEVYGIVDDEQLVLDLLLQEKILV
* : . . **:*.:. :. . : .** : :
MUL_4130|M.ulcerans_Agy99 APGIDFDTAGGNSFVRLSFAGPSEDIREALRRIESWLPER--
MMAR_5054|M.marinum_M APGIDFDTAGGNSFVRLSFAGPSEDIREALRRIESWLPER--
Mb3595|M.bovis_AF2122/97 APGIDFDTARGGSFVRISFAGPSGDIEEALRRIGSWLPSQ--
Rv3565|M.tuberculosis_H37Rv APGIDFDTARGGSFVRISFAGPSGDIEEALRRIGSWLPSQ--
MAV_0596|M.avium_104 APGIDFDTTRGNSFVRLSFAGPTTDIEEAVRRLGSWLRAR--
Mflv_1476|M.gilvum_PYR-GCK APGVDFDTVRGGAFVRLSFAGPSSDIEEALRRFGAWLP----
Mvan_5290|M.vanbaalenii_PYR-1 APGVDFDTVRGGAFVRLSFAGPASDLEEALRRIGAWLA----
TH_2065|M.thermoresistible__bu APGIDFDTVHGDRFVRFSFAGATSDIEEALRRIGGWLA----
MSMEG_6017|M.smegmatis_MC2_155 APGIDFDTVRGNSYVRLSFAGPTHDIEEALRRIGPWLG----
MAB_0685|M.abscessus_ATCC_1997 APGIDFDTVRGHRTVRLSFAGGSDEIAQALARMRPALGRG--
MLBr_02502|M.leprae_Br4923 TQGSGFNWP-APDHLRLVTLPWSRDLAAAIDRLGNFLVSYRQ
: * .*: . :*: : :: *: *: *