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VVDLSRRSDVPPFYVMDVLAAAATRQRTHGDMISLAAGQPSTGAPAVVLDAVREALGTQVLGYTETLGLP ELRSAIAAYHRERSDIAVTADDVVVTTGSSGGFTLLFLAAFDVGDTVVMTRPGYPAYRNCLAALGCRVVE LDCGPETRYQPTVAMLEALAQADGRVPAGLIVASPANPTGTIIDAGKLEAIALWCEANGTLLISDEIYHG LSYGDQKTSSAWEFSRESVVMGSVSKYFSMTGWRLGWMLVPRRFLRAVDRLSSNFTICPPAVSQYGALAA FSPEARDELDGHVRRYAANRTLLIDGLAAMGITKIAPPDGAFYAYADIEHLTDNAEQWCADLLARTGVAV APGIDFDTVRGHRTVRLSFAGGSDEIAQALARMRPALGRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0685 | - | - | 100% (390) | aspartate aminotransferase |
| M. abscessus ATCC 19977 | MAB_0847c | - | 5e-23 | 28.11% (370) | aminotransferase |
| M. abscessus ATCC 19977 | MAB_1328 | - | 6e-21 | 27.34% (384) | N-succinyldiaminopimelate aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3595 | aspB | 1e-125 | 59.26% (378) | aspartate aminotransferase |
| M. gilvum PYR-GCK | Mflv_1476 | - | 1e-131 | 61.74% (379) | aspartate aminotransferase |
| M. tuberculosis H37Rv | Rv3565 | aspB | 1e-125 | 59.26% (378) | aspartate aminotransferase |
| M. leprae Br4923 | MLBr_01488 | - | 6e-22 | 25.19% (393) | N-succinyldiaminopimelate aminotransferase |
| M. marinum M | MMAR_5054 | aspB | 1e-128 | 59.84% (381) | aspartate aminotransferase AspB |
| M. avium 104 | MAV_0596 | - | 1e-129 | 59.58% (381) | aspartate aminotransferase |
| M. smegmatis MC2 155 | MSMEG_6017 | - | 1e-135 | 63.71% (383) | aspartate aminotransferase |
| M. thermoresistible (build 8) | TH_2065 | aspB | 1e-128 | 60.58% (378) | POSSIBLE ASPARTATE AMINOTRANSFERASE ASPB (TRANSAMINASE A) |
| M. ulcerans Agy99 | MUL_4130 | aspB | 1e-126 | 59.06% (381) | aspartate aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_5290 | - | 1e-130 | 60.89% (381) | aspartate aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3595|M.bovis_AF2122/97 ---MTDRVALRAGVPPFYVMDVWLAAAERQRTHGD-LVNLSAGQPSAGAP
Rv3565|M.tuberculosis_H37Rv ---MTDRVALRAGVPPFYVMDVWLAAAERQRTHGD-LVNLSAGQPSAGAP
MMAR_5054|M.marinum_M MNAVNTHIARRAGIPPFYVMDVWLAAAERQRTHGD-LVNLSAGQPSVGAP
MUL_4130|M.ulcerans_Agy99 MNAVNTHIARRAGIPPFYVMDVWLAAAERQRTHGD-LVNLSAGQPSVGAP
MAV_0596|M.avium_104 ---MTDRVSLRAGIPPFYVMDVWLAAAERQRSHGD-LVNLSAGQPSVGAP
Mflv_1476|M.gilvum_PYR-GCK -----MTPSQRSGIPPFYVMDVWLAAAERQRTHGD-LVNLSAGQPSAGAP
Mvan_5290|M.vanbaalenii_PYR-1 -----MTVSQRSGIPPFYVMDVWLAAAERRRTHGD-LVNLSAGQPSAGAP
TH_2065|M.thermoresistible__bu ---MNDRTALRAGIPPFYVMDVWLAAAERQRSHGD-LVNLSAGQPSAGAP
MSMEG_6017|M.smegmatis_MC2_155 MGEMNDRVALRAGVPPFYVMDVWQAAAERQRTHGD-LVNLSAGQPSAGAP
MAB_0685|M.abscessus_ATCC_1997 ----MVDLSRRSDVPPFYVMDVLAAAATRQRTHGD-MISLAAGQPSTGAP
MLBr_01488|M.leprae_Br4923 ----MSPFGRVSATLPVFPWDTLADAKAVAESHPDGIVDLSVGTPVDPVA
. : *.: *. * .:* * ::.*:.* * ..
Mb3595|M.bovis_AF2122/97 EPVRAAAAAALHLNQLGYSVALGIPELRDAIAADYQRRHGITVEPDAVVI
Rv3565|M.tuberculosis_H37Rv EPVRAAAAAALHLNQLGYSVALGIPELRDAIAADYQRRHGITVEPDAVVI
MMAR_5054|M.marinum_M EPIRAAAAAALHLNELGYTVALGIPELRAAIAADYHRQHGISVEPEAVVI
MUL_4130|M.ulcerans_Agy99 EPIRAAAAAALHLNELGYTVALGIPELRAAIAADYHRQHGISVEPEAVVI
MAV_0596|M.avium_104 EPVRAAAAAAVHSNELGYSVSLGTPELRAAIAADYRRQHGLEVEPDAVVI
Mflv_1476|M.gilvum_PYR-GCK TAVRDAAVAALHRNQLGYTVALGIPELRTAIAGSYQDRHGLEVDPGDVVI
Mvan_5290|M.vanbaalenii_PYR-1 SAVRDAAVAALNRNDLGYTVALGIPELRAAIAGSYTARHGLTVDPDDVVV
TH_2065|M.thermoresistible__bu APVRAAAAATLERNQLGYTVALGIPELREAIAAGYQSRYGLSVGADEVVI
MSMEG_6017|M.smegmatis_MC2_155 APVRDAAAAALGRNQLGYTVALGIPELREQIAQTYHTRHDIDVGVDDVVL
MAB_0685|M.abscessus_ATCC_1997 AVVLDAVREALGTQVLGYTETLGLPELRSAIAAYHRERSDIAVTADDVVV
MLBr_01488|M.leprae_Br4923 PLIQEALAAAS--SVAGYPTTAGTARLREAAVAALDRRYGITGLTEAAVL
: * : . **. : * ..** . : .: .*:
Mb3595|M.bovis_AF2122/97 TTGSSGGFLLAFLACFDA--GDRVAMASPGYPCYRNILSALGCEVVEIPC
Rv3565|M.tuberculosis_H37Rv TTGSSGGFLLAFLACFDA--GDRVAMASPGYPCYRNILSALGCEVVEIPC
MMAR_5054|M.marinum_M TTGSSGGFLLTFLACFDV--GDRVALASPGYPCYRNILSALGCEVVEIPC
MUL_4130|M.ulcerans_Agy99 TTGSSGGFLLTFLACFDV--GDRVALASPGYPCYRNILSALGCEVVEIPC
MAV_0596|M.avium_104 TTGSSGGFLLTFLACFDV--GDRVAVASPGYPCYRNILSALGCEVVEIPC
Mflv_1476|M.gilvum_PYR-GCK TTGSSGGFLLAFLACFDV--GDRVAIASPGYPCYRNILSALGCEVVELPC
Mvan_5290|M.vanbaalenii_PYR-1 TTGSSGGFLLTFLACFDP--GDRVAIASPGYPCYRNILTALGCEVVELPC
TH_2065|M.thermoresistible__bu TTGSSGGFLLAFLACFDV--GDRVAIASPGYPCYRNILSALGCEVVELQC
MSMEG_6017|M.smegmatis_MC2_155 TTGSSGGFLLTFLACFDV--GDRVAITSPGYPCYRNILSALGCEVVEIPC
MAB_0685|M.abscessus_ATCC_1997 TTGSSGGFTLLFLAAFDV--GDTVVMTRPGYPAYRNCLAALGCRVVELDC
MLBr_01488|M.leprae_Br4923 PVIGTKELIAWLPTLLGLRAGDVVVVPELAYPTYNVGARLAGARVLRADS
.. .: : : : :. ** *.:. .** *. *..*:. .
Mb3595|M.bovis_AF2122/97 GPQTRFQPTAQMLAEIDPP----LRGVVVASPANPTGTVIPPEELAAIAS
Rv3565|M.tuberculosis_H37Rv GPQTRFQPTAQMLAEIDPP----LRGVVVASPANPTGTVIPPEELAAIAS
MMAR_5054|M.marinum_M GPETRFQPTADMLAQIDPP----VQGVIVASPANPTGTVIPPEELAAIAS
MUL_4130|M.ulcerans_Agy99 GPETRFQPTADMLAQIDPP----VQGVIVASPANPTGTVIPPEELAAIAS
MAV_0596|M.avium_104 GPQTRFQPTAAMLAELDPP----VQGVIVASPANPTGTVIAPEELAAIAS
Mflv_1476|M.gilvum_PYR-GCK GPDTRFQPTLQMLTELDPP----VSGVIVASPANPTGTVIAPEELAAIAA
Mvan_5290|M.vanbaalenii_PYR-1 GPKTRFQPTLQMLTELDPP----VSGVIVASPANPSGTVIPPAELAAIAT
TH_2065|M.thermoresistible__bu GPQTRFQPTARMLAELDPP----VRGVIVASPANPTGTVIPPEELAAIAR
MSMEG_6017|M.smegmatis_MC2_155 GPETRFQPTAAMLEALDPP----VQGVIVASPANPTGTVIAPEELAAIAR
MAB_0685|M.abscessus_ATCC_1997 GPETRYQPTVAMLEALAQADGRVPAGLIVASPANPTGTIIDAGKLEAIAL
MLBr_01488|M.leprae_Br4923 LTQLGLQSPALFY---------------LNSPSNPTGQVLAVNHLRKMVG
.. *.. : : **:**:* :: .* :.
Mb3595|M.bovis_AF2122/97 WCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSR----NAVVVNSFSKYY
Rv3565|M.tuberculosis_H37Rv WCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSR----NAVVVNSFSKYY
MMAR_5054|M.marinum_M WCDASGARLISDEVYHGLVYEGAPPTSCAWQTSR----NAVVVNSFSKYY
MUL_4130|M.ulcerans_Agy99 WCDASGARLISDEVYHGLVYEGAPPTSCARQTSR----NALVVNSFSKYY
MAV_0596|M.avium_104 WCEASGARLVSDEVYHGLVYEGAPPTSCAWQTSR----NAVVVNSFSKYY
Mflv_1476|M.gilvum_PYR-GCK WCETSGVRLISDEVYHGLVYPGAPATSCAWETSR----ESIVVNSFSKYF
Mvan_5290|M.vanbaalenii_PYR-1 WCESSGVRLISDEVYHGLVYPGAPATSCAWETSR----EAVVVNSFSKYF
TH_2065|M.thermoresistible__bu WCEDNDVRLISDEVYHGLVYPGAPETSCAWQTSR----EAVVVNSFSKYF
MSMEG_6017|M.smegmatis_MC2_155 WCDASGARLVSDEIYHGLVYEGAPETTCAWETSR----NAVVVNSFSKYF
MAB_0685|M.abscessus_ATCC_1997 WCEANGTLLISDEIYHGLSY-GDQKTSSAWEFSR----ESVVMGSVSKYF
MLBr_01488|M.leprae_Br4923 WARNRGVVVVSDECYLGLGWDAEPFSVLHPLVCDGNHTGLLAVHSLSKSS
*. .. ::*** * ** : . : . :.: *.**
Mb3595|M.bovis_AF2122/97 AMTGWRLGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAE
Rv3565|M.tuberculosis_H37Rv AMTGWRLGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAE
MMAR_5054|M.marinum_M AMTGWRLGWLLVPTELRRAVDCLTGNFTICPPVLSQVAAVSAFTPEATKE
MUL_4130|M.ulcerans_Agy99 AMTGWRLGWLLVPTELRRAVDCLTGNFTICPPVLSQVAAVSAFTPEATKE
MAV_0596|M.avium_104 AMTGWRLGWLLVPVELRRAVECLTGNFTICPPVLSQLAAVAAFTPEATAE
Mflv_1476|M.gilvum_PYR-GCK AMTGWRLGWLLVPDELKRAVDRLTGNFTICPPVLPQLAAVAAFTPESVAE
Mvan_5290|M.vanbaalenii_PYR-1 AMTGWRLGWLLVPDELKRAVDRLTGNFTICPPALPQIAAVSAFTPESIAE
TH_2065|M.thermoresistible__bu AMTGWRLGWLLVPPALLRAVDRLTGNFTICPPALAQVAAVEAFHPESIAE
MSMEG_6017|M.smegmatis_MC2_155 AMTGWRLGWLLVPEKLRRAVDCLTGNFTICPPALAQYAALAAFTPESLAE
MAB_0685|M.abscessus_ATCC_1997 SMTGWRLGWMLVPRRFLRAVDRLSSNFTICPPAVSQYGALAAFSPEARDE
MLBr_01488|M.leprae_Br4923 SLAGYRAGFVAGDPDLVAELLAVRKHAGMMVPTPVQAAMVAALGDDAHER
:::*:* *:: : : : : : *. * . : *: :: .
Mb3595|M.bovis_AF2122/97 ADGNLASYAINRSLLLDGLRRIGIDRLAPTDGAFYVYADVSDFTSDSLAF
Rv3565|M.tuberculosis_H37Rv ADGNLASYAINRSLLLDGLRRIGIDRLAPTDGAFYVYADVSDFTSDSLAF
MMAR_5054|M.marinum_M ADGNLRHYASNRSTLLDGLRRIGIDRLAPTDGAFYVYADVSDFTDDSLKF
MUL_4130|M.ulcerans_Agy99 ADDNLRHYASNRSTLLDGLRRIGIDRLAPTDGAFYVYADVSDFTDDSFKF
MAV_0596|M.avium_104 ADGHLHHYAKNRALLLDGLRGIGITRLAPTDGAFYVYADVSDFTDNSMEF
Mflv_1476|M.gilvum_PYR-GCK AESLLEGYGANRTMLLDGLRALGIDRLAPTDGAFYVYADVSHLTTDSLSF
Mvan_5290|M.vanbaalenii_PYR-1 AEALLHDYAANRTLLLDGLSALGIDRLAPTDGAFYVYADVSHLTTDSLAF
TH_2065|M.thermoresistible__bu AEALLDHYATNRRLLIDGLRSLGIDRLAPADGAFYVYADVSRYTEDSIEF
MSMEG_6017|M.smegmatis_MC2_155 AEGLLTHYAENRHLLLNGLRGLGIDKLAPTDGAFYVYADVSKYTDNSLQF
MAB_0685|M.abscessus_ATCC_1997 LDGHVRRYAANRTLLIDGLAAMGITKIAPPDGAFYAYADIEHLTDNAEQW
MLBr_01488|M.leprae_Br4923 EQ--RDRYARRRDVLLPAVVSAGFT-VDHSEAGLYLWASRGEPCRDSVEW
: *. .* *: .: *: : .:..:* :*. :: :
Mb3595|M.bovis_AF2122/97 CSKLLADTGVAIAPGIDFDTARGGSFVRISFAGPSGDIEEALRRIGSWLP
Rv3565|M.tuberculosis_H37Rv CSKLLADTGVAIAPGIDFDTARGGSFVRISFAGPSGDIEEALRRIGSWLP
MMAR_5054|M.marinum_M CSKLLADTGVAIAPGIDFDTAGGNSFVRLSFAGPSEDIREALRRIESWLP
MUL_4130|M.ulcerans_Agy99 CSKLLADTGVAIAPGIDFDTAGGNSFVRLSFAGPSEDIREALRRIESWLP
MAV_0596|M.avium_104 CSKLLEQTGVAIAPGIDFDTTRGNSFVRLSFAGPTTDIEEAVRRLGSWLR
Mflv_1476|M.gilvum_PYR-GCK CSKLLADTGVAIAPGVDFDTVRGGAFVRLSFAGPSSDIEEALRRFGAWLP
Mvan_5290|M.vanbaalenii_PYR-1 CSKLLDDTGVAIAPGVDFDTVRGGAFVRLSFAGPASDLEEALRRIGAWLA
TH_2065|M.thermoresistible__bu CSKLLADTGVAIAPGIDFDTVHGDRFVRFSFAGATSDIEEALRRIGGWLA
MSMEG_6017|M.smegmatis_MC2_155 CEKLLNDTGVAIAPGIDFDTVRGNSYVRLSFAGPTHDIEEALRRIGPWLG
MAB_0685|M.abscessus_ATCC_1997 CADLLARTGVAVAPGIDFDTVRGHRTVRLSFAGGSDEIAQALARMRPALG
MLBr_01488|M.leprae_Br4923 F----AQRGILVALG-EFYGPGGCQHVRVALTASDERIAAVVARLS----
*: :* * :* * **.:::. : .: *:
Mb3595|M.bovis_AF2122/97 SQ
Rv3565|M.tuberculosis_H37Rv SQ
MMAR_5054|M.marinum_M ER
MUL_4130|M.ulcerans_Agy99 ER
MAV_0596|M.avium_104 AR
Mflv_1476|M.gilvum_PYR-GCK --
Mvan_5290|M.vanbaalenii_PYR-1 --
TH_2065|M.thermoresistible__bu --
MSMEG_6017|M.smegmatis_MC2_155 --
MAB_0685|M.abscessus_ATCC_1997 RG
MLBr_01488|M.leprae_Br4923 --