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M. vanbaalenii PYR-1 Mvan_5287 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 5663934 - 5665058
length: 374

LDLTFDDATSEFRAEVRDFLAANKSAFPTKSYDTAEGFEQHRRWDKVLFDAGLSVITWPEKYGGRDASLL
QWIVYEEEYFRAGAPGRASANGTSMLAPTLFAHGTEEQLDRILPKMASGEEIWAQAWSEPESGSDLASLR
STATRTDGGWLLNGQKIWSSRAVFGERAFGLFRSDPEAQRHKGLTYFMFDLKAKGVTVRPIAQLGGDTGF
GEIFLDDVFVPDQDVIGGVHDGWRAAMSTSSNERGMSLRSPARFLAPAERLVAQWKDNPDPAFTDRVADA
WIKAQAYRLHTFGTVTRVSNGGELGAESSITKVFWSELDVALHQTALDLRGADGELTDSVTEGLLFALGG
PIYAGTNEIQRNIIAERLLGLPRK

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. vanbaalenii PYR-1 Mvan_5287 - - 100% (374) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_5285 - 1e-65 38.44% (385) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_4006 - 1e-61 36.63% (404) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3592 fadE31 0.0 84.80% (375) acyl-CoA dehydrogenase FADE31
M. gilvum PYR-GCK Mflv_1479 - 0.0 94.92% (374) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3562 fadE31 0.0 84.80% (375) acyl-CoA dehydrogenase FADE31
M. leprae Br4923 MLBr_00737 fadE25 6e-22 25.90% (332) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0595c - 1e-167 73.87% (375) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_5051 fadE31 1e-180 81.07% (375) acyl-CoA dehydrogenase FadE31
M. avium 104 MAV_0599 - 0.0 83.47% (375) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_6014 - 0.0 90.11% (374) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_2586 - 0.0 86.68% (383) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_4127 fadE31 1e-179 80.53% (375) acyl-CoA dehydrogenase FadE31

CLUSTAL 2.0.9 multiple sequence alignment


Mb3592|M.bovis_AF2122/97            ----------MDLNFDDETLAFQAEVREFLAANAASIPTKSYDNAEGFAQ
Rv3562|M.tuberculosis_H37Rv         ----------MDLNFDDETLAFQAEVREFLAANAASIPTKSYDNAEGFAQ
MMAR_5051|M.marinum_M               ----------MDLDLDEETLAFQGEVREFLAANAEVMPTKSYDNAQGFAQ
MUL_4127|M.ulcerans_Agy99           ----------MDLDLDEETLAFQGEVREFLAANAEVMPTKSYDNAQGFAQ
MAV_0599|M.avium_104                ----------MDLDLDEGTLAFRDEVRQFLSANAEAIPTKSYDNAEGFEQ
Mvan_5287|M.vanbaalenii_PYR-1       ----------MDLTFDDATSEFRAEVRDFLAANKSAFPTKSYDTAEGFEQ
Mflv_1479|M.gilvum_PYR-GCK          ----------MDLTFDDATLDFQAEVREFLAANKGSFPTKSYDTADGFEQ
TH_2586|M.thermoresistible__bu      ----------MDLHIDDATEEFRAEVREFLANNRKWFPTKSYDTAEGFEQ
MSMEG_6014|M.smegmatis_MC2_155      ----------MDLKFDEETEAFRAEVREFLAANRENFPTKSYDTKEGFEQ
MAB_0595c|M.abscessus_ATCC_199      ----------MDLLLDDETEAFRAEVREFLVSNVPNPPLPSYDSPEGAAA
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAP---HAADVDQRARF
                                                : : :    ::  :* :   :       : *  :    

Mb3592|M.bovis_AF2122/97            HRYWDRVLFDAGLSVITWPAKYGGRDAPLLHWIVFEEEYFRAGAPGRASA
Rv3562|M.tuberculosis_H37Rv         HRYWDRVLFDAGLSVITWPAKYGGRDAPLLHWIVFEEEYFRAGAPGRASA
MMAR_5051|M.marinum_M               HRVWDRVLFDAGLSVITWPKQYGGRDAPLLHWVIFEEEYFRAGAPGRASA
MUL_4127|M.ulcerans_Agy99           HRVWDRVLFDAGLSVITWPKQYGGRDAPLLHWVIFEEEYFRAGAPGRASA
MAV_0599|M.avium_104                HRRWDRVLYDAGLSVITWPKKYGGRDAPLLHWVVFEEEYFRAGAPGRASA
Mvan_5287|M.vanbaalenii_PYR-1       HRRWDKVLFDAGLSVITWPEKYGGRDASLLQWIVYEEEYFRAGAPGRASA
Mflv_1479|M.gilvum_PYR-GCK          HRRWDKVLFDAGLSVITWPEKYGGRDASLLQWIVYEEEYFRAGAPGRASA
TH_2586|M.thermoresistible__bu      HRQWDRVLYDARLSVITWPEKYGGRDATLLQWVVFEEEYFRAGAPGRASA
MSMEG_6014|M.smegmatis_MC2_155      HRRWDKALFDAGLSVIAWPKKYGGRDATLLQWVVFEEEYFRAGAPGRASA
MAB_0595c|M.abscessus_ATCC_199      HRQWERTLYDAGFSAVSWPKEYGGRDVTPLQWVIFEEEYFKAGAPARISQ
MLBr_00737|M.leprae_Br4923          PEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIP
                                     .    .*  : :..:  * :***:..  :   :  **  :..*..    

Mb3592|M.bovis_AF2122/97            NGTSMLAPTLFAHGTAEQLDRILPKMASGEQIWAQAWSEPESGSDLASLR
Rv3562|M.tuberculosis_H37Rv         NGTSMLAPTLFAHGTAEQLDRILPKMASGEQIWAQAWSEPESGSDLASLR
MMAR_5051|M.marinum_M               NGTSMLAPTLFAHGTAEQLDRILLKMASGEQIWAQAWSEPESGSDLASLR
MUL_4127|M.ulcerans_Agy99           NGTSMLAPTLFAHGTAEQLDRILLKMASGEQIWAQTWSEPESGSDLASLR
MAV_0599|M.avium_104                NGTSMLAPTLFAHGTEEQRDRILPKMASGEEIWAQAWSEPESGSDLASLR
Mvan_5287|M.vanbaalenii_PYR-1       NGTSMLAPTLFAHGTEEQLDRILPKMASGEEIWAQAWSEPESGSDLASLR
Mflv_1479|M.gilvum_PYR-GCK          NGTSMLAPTLFAHGTEEQRDRILPKMASGEEIWAQAWSEPESGSDLASLR
TH_2586|M.thermoresistible__bu      NGTSMLAPTLFAHGTEEQLDRVLPKMATGEEIWAQAWSEPESGSDLASLR
MSMEG_6014|M.smegmatis_MC2_155      NGTSMLAPTLFAHGTSEQLDRVLPKMASGEEIWAQAWSEPESGSDLASLR
MAB_0595c|M.abscessus_ATCC_199      NGMFLLGPTLFAHGSKDQLDRVLPKMANGEEIWAQAWSEPESGSDLASLR
MLBr_00737|M.leprae_Br4923          AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMR
                                        :    *: :*: :  .::* .:*    : : : ** *:*** **:*

Mb3592|M.bovis_AF2122/97            STASKVDGGWLLNGQKIWSSRAPFADMGFGLFRSDPAVERHRGLTYFMFD
Rv3562|M.tuberculosis_H37Rv         STASKVDGGWLLNGQKIWSSRAPFADMGFGLFRSDPAVERHRGLTYFMFD
MMAR_5051|M.marinum_M               STATKTDGGWLLNGQKIWSSRAPFADMGFGLFRSDPSAQRHRGLTYFMFD
MUL_4127|M.ulcerans_Agy99           STATKTDGGWLLNGQKIWSSRAPFADMGFGLFRSDPSAQRHRGLTYFMFD
MAV_0599|M.avium_104                STATPTDGGWLLNGQKIWSSRAPFAERGFGLFRSDPSAERHHGLTYFMFD
Mvan_5287|M.vanbaalenii_PYR-1       STATRTDGGWLLNGQKIWSSRAVFGERAFGLFRSDPEAQRHKGLTYFMFD
Mflv_1479|M.gilvum_PYR-GCK          STATRTEGGWLLNGQKIWSSRAVFGERAFGLFRSDPAAQRHKGLTYFMFD
TH_2586|M.thermoresistible__bu      STATKTDGGWLLNGQKIWSSRAVFGERAFGLFRSDPQAQRHKGLTYFMFD
MSMEG_6014|M.smegmatis_MC2_155      STATKTDGGWLLNGQKIWSSRAVFGERGFGLFRSDPEAQRHKGLTYFMFD
MAB_0595c|M.abscessus_ATCC_199      SPARKVDGGWRLSGQKIWSSRAPFADRAFGLFRSDPDAQRHQGLTYFMFD
MLBr_00737|M.leprae_Br4923          TRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDP-DKGANGISAFIVH
                                    : *    ..* *.* * * :..  .     :  :**  :  .*:: *:..

Mb3592|M.bovis_AF2122/97            LKAKGVTVRPIAQLGGDTG--FGEIFLDDVFVPDRDVIGAPNDGWRAAMS
Rv3562|M.tuberculosis_H37Rv         LKAKGVTVRPIAQLGGDTG--FGEIFLDDVFVPDRDVIGAPNDGWRAAMS
MMAR_5051|M.marinum_M               LKAKGITVRPIVQLGGDTG--FGEIFLDDVFVPDQDVIGAPNDGWRAAMS
MUL_4127|M.ulcerans_Agy99           LKAKGITVRPIVQLGGDTG--FGEIFLDDVFVPDQDVIGAPNDGWRAAMS
MAV_0599|M.avium_104                LKAEGVTVRPIVQLGGDTG--FGEIFLDDVFVPDRDVIGTPHQGWRAAMS
Mvan_5287|M.vanbaalenii_PYR-1       LKAKGVTVRPIAQLGGDTG--FGEIFLDDVFVPDQDVIGGVHDGWRAAMS
Mflv_1479|M.gilvum_PYR-GCK          LKADGVTVRPIAQLGGDTG--FGEIFLDDVFVPDDDVIGEVHDGWRAAMS
TH_2586|M.thermoresistible__bu      LRADGVTVRPIAQLGGDTG--FGEIFLDNVFVPDNDVIGEVNEGWRAAMS
MSMEG_6014|M.smegmatis_MC2_155      LKAQGVTVRPIAQLGGDTG--FGEIFFDDVFVPDNDVIGGVHDGWRAAMS
MAB_0595c|M.abscessus_ATCC_199      LKAEGITVRPIPQLDGDPG--FAEIFLDDVFVPDEDVIGAVHDGWRVAMS
MLBr_00737|M.leprae_Br4923          KDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALA
                                       .*.:: *  :  *  *    *:::*.  :*.  :**    *::.*::

Mb3592|M.bovis_AF2122/97            TSSNER--------GMSLRSPARFLASAERLVQLWKDRGSPPEFADRVAD
Rv3562|M.tuberculosis_H37Rv         TSSNER--------GMSLRSPARFLASAERLVQLWKDRGSPPEFADRVAD
MMAR_5051|M.marinum_M               TSSNER--------GMSLRSPARFMAAAQKLVQLWKDAGSPPEFANRVAD
MUL_4127|M.ulcerans_Agy99           TSSNER--------GMSLRSPARFMAAAQKLVQLWKDAGSPPEFANRVAD
MAV_0599|M.avium_104                TSSNER--------GMSLRSPARFLATAERVVRLWQDRGSPAEFADRVAD
Mvan_5287|M.vanbaalenii_PYR-1       TSSNER--------GMSLRSPARFLAPAERLVAQWKDNPDP-AFTDRVAD
Mflv_1479|M.gilvum_PYR-GCK          TSSNER--------GMSLRSPARFLAPAERLVAQWKDNPDP-VFTDRVAD
TH_2586|M.thermoresistible__bu      TSSNER--------GMSLRSPARFLAPAERLVRLWKQNPDP-AFEERVAD
MSMEG_6014|M.smegmatis_MC2_155      TSSNER--------GMSLRSPARFLAPAERLVERWKENPDP-AFTDRVAD
MAB_0595c|M.abscessus_ATCC_199      TSSNER--------GMSLRSPGRFLATADRLVELWKSVPENEFASERVAD
MLBr_00737|M.leprae_Br4923          TLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLAD
                                    * .: *        *::  :    :. :.      :.          :**

Mb3592|M.bovis_AF2122/97            AWIKAQAYRLQTFGTVTRLAAGG-ELGAESSVTKVFWSELDVHLHQTALD
Rv3562|M.tuberculosis_H37Rv         AWIKAQAYRLQTFGTVTRLAAGG-ELGAESSVTKVFWSELDVHLHQTALD
MMAR_5051|M.marinum_M               AWIKAQAYRLQTFGTVTRLAAGG-ELGAESSVTKVFWSDLDVDIHQTALD
MUL_4127|M.ulcerans_Agy99           AWIKAQAYRLQTFGTVTRLAAGG-ELGAGSSVTKVFWSDLDVDIHQTALD
MAV_0599|M.avium_104                GWIKAQAYRLQTFGTVTRLAAGG-ELGAESSVTKVFWSDLDVELHQTALD
Mvan_5287|M.vanbaalenii_PYR-1       AWIKAQAYRLHTFGTVTRVSNGG-ELGAESSITKVFWSELDVALHQTALD
Mflv_1479|M.gilvum_PYR-GCK          AWIKAQAYRLHTFGTVTRVAGGG-ELGAESSITKVFWSDLDVALHQTALD
TH_2586|M.thermoresistible__bu      AWIKAQAYRLHTFGTVSRLARGG-ELGAESSVTKVFWSELDVALHQTALD
MSMEG_6014|M.smegmatis_MC2_155      AWIKAQAYRLHTFGTVTRLANGG-ELGAESSVTKVFWSDLDVALHQTALD
MAB_0595c|M.abscessus_ATCC_199      AWIAAQAYRLHTFGTVTRLAGGG-ELGAESSITKVFWSELDVALHETAID
MLBr_00737|M.leprae_Br4923          MAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQ
                                      : .:* ** .:.:.:*   *  :**  *: :* * *:: : :   *::

Mb3592|M.bovis_AF2122/97            LRGADGELAGPW---------TEGLLFALGGPIYAGTNEIQRNIIAERLL
Rv3562|M.tuberculosis_H37Rv         LRGADGELAGPW---------TEGLLFALGGPIYAGTNEIQRNIIAERLL
MMAR_5051|M.marinum_M               IRGADAELVSPW---------TEGLLFALGGPIYAGTNEIQRNIISERLL
MUL_4127|M.ulcerans_Agy99           IRGADAELVSPW---------TEGLLFALGGPIYAGTNEIQRNIISERLL
MAV_0599|M.avium_104                ILAADGELAGPW---------TEGLLFALGGPIYAGTNEIQRNIISERLL
Mvan_5287|M.vanbaalenii_PYR-1       LRGADGELTDSV---------TEGLLFALGGPIYAGTNEIQRNIIAERLL
Mflv_1479|M.gilvum_PYR-GCK          LRGADGELMDPV---------TEGLLFALGGPIYAGTNEIQRNIIAERLL
TH_2586|M.thermoresistible__bu      LRGPDAELADSADRDEDGYSWTDGLLFALGGPIYAGTNEIQRNIIAERLL
MSMEG_6014|M.smegmatis_MC2_155      LAGADGELVGNW---------TEGLLFALGGPIYAGTNEIQRNIIAERLL
MAB_0595c|M.abscessus_ATCC_199      LRGAEGELTNAW---------TDGYLFSLGGPIYAGTNEIQRNIIAERIL
MLBr_00737|M.leprae_Br4923          LFGGAGYTSDFP--------VERFMRDAKITQIYEGTNQIQRVVMSRALL
                                    : .  .   .                 :    ** ***:*** :::. :*

Mb3592|M.bovis_AF2122/97            GLPREKT---------
Rv3562|M.tuberculosis_H37Rv         GLPREKT---------
MMAR_5051|M.marinum_M               GLPREKK---------
MUL_4127|M.ulcerans_Agy99           GLPREKK---------
MAV_0599|M.avium_104                GLPREKSGSKK-----
Mvan_5287|M.vanbaalenii_PYR-1       GLPRK-----------
Mflv_1479|M.gilvum_PYR-GCK          GLPRK-----------
TH_2586|M.thermoresistible__bu      GLPRK-----------
MSMEG_6014|M.smegmatis_MC2_155      GLPRESAGKSK-----
MAB_0595c|M.abscessus_ATCC_199      GLPRESSASARTGGAK
MLBr_00737|M.leprae_Br4923          R---------------

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_5287	-	-	100% (374)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_5285	-	1e-65	38.44% (385)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_4006	-	1e-61	36.63% (404)	acyl-CoA dehydrogenase domain-containing protein