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ARGLQGAVLRGFGARDHTATVVETVYIAPHFLRIRMVSPTLFEDAQAEPAAWLRFWFPDPKGSNTEYQRA YTLSEADAASGRFAVDVVLHEPAGPASQWARTVQPGATIAVMSLMGSSSRFDVPKEQPAGYLLIGDSASI PGMNGIIGTVPDDVPIEMYLEQHDDNDTRIPITAHPRLRVHWVPRRDETSLAEAIETRDWSDWYAWATPE ATALKHVRKRLRDAFGFPKSVVHAQAYWTAGREMGTCREGVPDAAADGASTCLDDQPEVALAQAETPEPV AQSPVAATPRGSWRAQAAGRLLAPLRFALILSGVLQVVATLVQLAPFVLLVELARILLSGAQESRLWHVG LAAVSLLGLGTLLGAALTLWLHVVDARFARGLRARLLGKMSGLPLGWFTGRGSGSIKQLVQDDTLSLHYL VTHAIPDAVNAVVAPVAVLVYLFIVDWRVALVLLIPVLMYLVMTSSLAVQSGSRMVASQRWAERMNDEAG AYLEGQPVIRVFGGAAASSFKRQLDEYIKFLVTWQRPLVGKKTMMDLATRPSTFLWLIAVTGTLLVINHR MDPVDLLPFLLLGTTFGVRLLGIAYGIGGISAGVLAARRLQITLDEPVLEQHTGLAEADSAAMVVFDKVS FGYRPGVPVIRDVSLQLRPGTVTALVGPSGSGKSTLAALLARFHDVEQGSIRAGGQDIRSLSADELYERV GLVLQETQLVHGTVAENIALAVPDAPAAQIQAAAGQAQIHDRVLRLRDGYDTVLGAGAALSGGERQRLTI ARAILADTPVLILDEATAYADPESEYLVQQALNRLIKDRTVLVIAHRLHTITGADQIVVLDRGQIAERGT HDELLAADGRYRRLWETGCGNQVELAAIQEGAR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_3902 | - | - | 100% (874) | transmembrane ATP-binding protein ABC transporter |
M. ulcerans Agy99 | MUL_4011 | - | 2e-68 | 35.00% (540) | transmembrane ATP-binding protein ABC transporter |
M. ulcerans Agy99 | MUL_3901 | - | 2e-58 | 31.82% (594) | transmembrane ATP-binding protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1383 | - | 0.0 | 76.97% (877) | drugs-transport transmembrane ATP-binding protein ABC |
M. gilvum PYR-GCK | Mflv_2250 | - | 3e-74 | 37.15% (533) | ABC transporter, transmembrane region |
M. tuberculosis H37Rv | Rv1348 | - | 0.0 | 76.97% (877) | drugs-transport transmembrane ATP-binding protein ABC |
M. leprae Br4923 | MLBr_01113 | - | 1e-65 | 35.21% (514) | putative ABC transporter, ATP-binding component |
M. abscessus ATCC 19977 | MAB_2262c | - | 0.0 | 61.93% (872) | ABC transporter ATP-binding protein |
M. marinum M | MMAR_4037 | - | 0.0 | 99.43% (874) | transmembrane ATP-binding protein ABC transporter |
M. avium 104 | MAV_1566 | - | 0.0 | 77.85% (867) | putative ABC transporter ATP-binding protein |
M. smegmatis MC2 155 | MSMEG_6554 | - | 0.0 | 70.53% (862) | ABC transporter ATP-binding protein |
M. thermoresistible (build 8) | TH_2699 | - | 0.0 | 71.74% (559) | PUTATIVE hypothetical ABC transporter ATP-binding protein |
M. vanbaalenii PYR-1 | Mvan_4441 | - | 2e-70 | 36.22% (519) | ABC transporter, transmembrane region |
CLUSTAL 2.0.9 multiple sequence alignment MUL_3902|M.ulcerans_Agy99 MARGLQGAVLRGFGARDHTATVVETVYIAPHFLRIRMVSPTLFEDAQAEP MMAR_4037|M.marinum_M MARGLQGAVLRGFGARDHTATVVETVYIAPHFLRIRMVSPTLFEDAQAEP Mb1383|M.bovis_AF2122/97 MARGLQGVMLRSFGARDHTATVIETISIAPHFVRVRMVSPTLFQDAEAEP Rv1348|M.tuberculosis_H37Rv MARGLQGVMLRSFGARDHTATVIETISIAPHFVRVRMVSPTLFQDAEAEP MAV_1566|M.avium_104 -------MMLRSFGARDHTATVLETVRIAPHFVRVRMTSPTLFEDVDAEP MSMEG_6554|M.smegmatis_MC2_155 MARGIQGVMMRGFGARDHQATVVSTEAITPNLLRLRMVSPTLFEDAVAEP TH_2699|M.thermoresistible__bu -------------------------------------------------- MAB_2262c|M.abscessus_ATCC_199 MGRGFQGAILRGLGARDHVATVVGTAPVAPNCVRITMSAPTLFEDLLHTP Mflv_2250|M.gilvum_PYR-GCK ------------------------MSGPLARGIRMGEPPQERSRDFKASA Mvan_4441|M.vanbaalenii_PYR-1 ------------------------MTGPLARSMRMAEPPQTRSRDFTGSA MLBr_01113|M.leprae_Br4923 --------------------------------MTMATAPATRSCDFYCTI MUL_3902|M.ulcerans_Agy99 AAWLRFWFPDPKGSNTEYQRAYTLSEADAASGRFAVDVVLHEPAGPASQW MMAR_4037|M.marinum_M AAWLRFWFPDPKGSNTEYQRAYTLSEADAASGRFAVDVVLHEPAGPASQW Mb1383|M.bovis_AF2122/97 AAWLRFWFPDPNGSNTEFQRAYTISEADPAAGRFAVDVVLHDPAGPASSW Rv1348|M.tuberculosis_H37Rv AAWLRFWFPDPNGSNTEFQRAYTISEADPAAGRFAVDVVLHDPAGPASSW MAV_1566|M.avium_104 AAWLRFWFPDPDGSKTEFQRAYTISEADPTAGRFAVDVVLHDPAGPASRW MSMEG_6554|M.smegmatis_MC2_155 TSWLRFWFPDPAGSKTEFQRAYTMSEMSPETGEFAIDVVLHEPAGPASRW TH_2699|M.thermoresistible__bu -------------------------------------------------- MAB_2262c|M.abscessus_ATCC_199 AEWLRFWFPDPDGGTSEHQRAYTIVTTDEDAGEFSIDVVIHEPAGPACQW Mflv_2250|M.gilvum_PYR-GCK IRLLRRLTP---------QRGMTIAVMLLGVGGIAIGVVGPRILGHATDL Mvan_4441|M.vanbaalenii_PYR-1 LRLFRRLTP---------QRGMTVAVMLLGVGGIAIGVIGPRILGHATDL MLBr_01113|M.leprae_Br4923 RRLLKQLVP---------QRRLSLTVITLGITGTAIGIIVPWVLGHTTDL MUL_3902|M.ulcerans_Agy99 ARTVQPGATIAVMSLMGSSSRFDVPKEQPAGYLLIGDSASIPGMNGIIGT MMAR_4037|M.marinum_M ARTVQPGATIAVMSLMGSSSRFDVPKEQPAGYLLIGDSASIPGMNGIIGT Mb1383|M.bovis_AF2122/97 ARTVKPGATIAVMSLMGSS-RFDVPEEQPAGYLLIGDSASIPGMNGIIET Rv1348|M.tuberculosis_H37Rv ARTVKPGATIAVMSLMGSS-RFDVPEEQPAGYLLIGDSASIPGMNGIIET MAV_1566|M.avium_104 ARTVQPGATIAVMALMGSS-RFDVPDEQPAGYLLIGDSASIPGMNGIIGV MSMEG_6554|M.smegmatis_MC2_155 ARSAKPGDAIAVMTLGSAG--FSVPEDPPAGYLLIGDAAATPAINGIIGV TH_2699|M.thermoresistible__bu -------------------------------------------------- MAB_2262c|M.abscessus_ATCC_199 AVAAQPGMTIPVVAFGSAR--FEVPADLPSGFLLIGDSASIPAINSIVAA Mflv_2250|M.gilvum_PYR-GCK LFNGVIG------------------------------------------- Mvan_4441|M.vanbaalenii_PYR-1 LFNGVIG------------------------------------------- MLBr_01113|M.leprae_Br4923 LFNGVIG------------------------------------------- MUL_3902|M.ulcerans_Agy99 VPDDVPIEMYLEQHDDNDTRIPITAHPRLRVHWVPRRDETSLAEAIETRD MMAR_4037|M.marinum_M VPDDVPIEMYLEQHDDNDTRIPITAHSRLRVHWVRRRDETSLAEAIETRD Mb1383|M.bovis_AF2122/97 VPNDVPIEMYLEQHDDNDTLIPLAKHPRLRVRWVMRRDEKSLAEAIENRD Rv1348|M.tuberculosis_H37Rv VPNDVPIEMYLEQHDDNDTLIPLAKHPRLRVRWVMRRDEKSLAEAIENRD MAV_1566|M.avium_104 VPDDVPIEMYLEQHHDDDTLIPIAVHPRLRVHWVARRDEKSLAAALESRD MSMEG_6554|M.smegmatis_MC2_155 VPHDIPIEVYLEEHDENDRLIPIAEHPRMRVHWVVREDATSLAGAIEARD TH_2699|M.thermoresistible__bu -------------------------------------------------- MAB_2262c|M.abscessus_ATCC_199 LPAEVDIEVYLERHSPDDELIPLTTHPRRRLHWVDRIDETSLAAAIEGRD Mflv_2250|M.gilvum_PYR-GCK ------------------RQLPAGSTKEQAIEAARARGDTTFADLLSG-- Mvan_4441|M.vanbaalenii_PYR-1 ------------------RQLPAGLTKEQAVEAARARGDGTFADLLSG-- MLBr_01113|M.leprae_Br4923 ------------------RQLPKGISKTQAVAAARTRGDNALADLLSG-- MUL_3902|M.ulcerans_Agy99 WSDWYAWATPEATALKHVRKRLRDAFGFPKSVVHAQAYWTAGREMGTCRE MMAR_4037|M.marinum_M WSDWYAWATPEATALKHVRKRLRDAFGFPKSVVHAQAYWTAGREMGTCRE Mb1383|M.bovis_AF2122/97 WSDWYAWATPEAAALKCVRVRLRDEFGFPKSEIHAQAYWNAGRAMGTHRA Rv1348|M.tuberculosis_H37Rv WSDWYAWATPEAAALKCVRVRLRDEFGFPKSEIHAQAYWNAGRAMGTHRA MAV_1566|M.avium_104 WSNWYAWATPEATTLKHVRARLRDEFGFPKSEVHAQAYWSAGRAMGTRRG MSMEG_6554|M.smegmatis_MC2_155 WSNWYCWVTPEAGSLKHLRTRLRDEFGFPKAELHPQAYWTEGRAMGTKRG TH_2699|M.thermoresistible__bu -------------------------------------------------- MAB_2262c|M.abscessus_ATCC_199 WSNWYGWASSESGSLKHLRKRLRDEFGFPKADVHAAAYWTFGRAMGSRRG Mflv_2250|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4441|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_3902|M.ulcerans_Agy99 GVPDAAADGASTCLDDQPEVALAQAETPEPVAQSPVAATPRGSWRAQAAG MMAR_4037|M.marinum_M GVPDAAAGGASTCLDDQPEVALAQAETPEPVAQSPVAATPRGSWRAQAAG Mb1383|M.bovis_AF2122/97 TEPAAT----------EPEVG------AAPQPESAVPAPARGSWRAQAAS Rv1348|M.tuberculosis_H37Rv TEPAAT----------EPEVG------AAPQPESAVPAPARGSWRAQAAS MAV_1566|M.avium_104 DESATTDGGTEAAEDIAAQVD-----SPQRQPEAAPVPAARGNWRTQAAG MSMEG_6554|M.smegmatis_MC2_155 DDDKTP--------EVNPAPR------ADKPEAPAPAAAGRGNWRAQAAG TH_2699|M.thermoresistible__bu -------------------------------------------------- MAB_2262c|M.abscessus_ATCC_199 DSETPQ--------KATPKPVVVPTDTQVKPSATPETTAPQGRWRSQAAG Mflv_2250|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4441|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_3902|M.ulcerans_Agy99 RLLAPLRFALILSGVLQVVATLVQLAPFVLLVELARILLSGAQESRLWHV MMAR_4037|M.marinum_M RLLAPLRFALILSGVLQVVATLVQLAPFVLLVELARILLSGAQESRLWHV Mb1383|M.bovis_AF2122/97 RLLAPLKLPLVLSGVLAALVTLAQLAPFVLLVELSRLLVSGAGAHRLFTV Rv1348|M.tuberculosis_H37Rv RLLAPLKLPLVLSGVLAALVTLAQLAPFVLLVELSRLLVSGAGAHRLFTV MAV_1566|M.avium_104 RLLAPLRWALILSGVLQAVITLIQLAPFVLLVELVRRLVAGAPAARLWDV MSMEG_6554|M.smegmatis_MC2_155 RLLAPLKTTLIISGVLQAIITLVQLAPFVLLVELARLLLSGASSDRLWTL TH_2699|M.thermoresistible__bu ----------------------------VLLVELARLLLGGAEAERLWTL MAB_2262c|M.abscessus_ATCC_199 ELLAPVKKQMIAGGVLQAIITMVELAPFVVLVELTRQLLAGADEAQLRHT Mflv_2250|M.gilvum_PYR-GCK ---------------------------------MDVVPGQGVDFAAVART Mvan_4441|M.vanbaalenii_PYR-1 ---------------------------------MDVVPGQGVDFGAVGRT MLBr_01113|M.leprae_Br4923 ---------------------------------MNLVPGQGVDFVAVGRT : *. : MUL_3902|M.ulcerans_Agy99 GLAAVSLLGLGTLLGAALTLWLHVVDARFARGLRARLLGKMSGLPLGWFT MMAR_4037|M.marinum_M GLAAVSLLGLGTLLGAALTLWLHVVDARFARGLRARLLGKMSGLPLGWFT Mb1383|M.bovis_AF2122/97 GFAAVGLLGTGALLAAALTLWLHVIDARFARALRLRLLSKLSRLPLGWFT Rv1348|M.tuberculosis_H37Rv GFAAVGLLGTGALLAAALTLWLHVIDARFARALRLRLLSKLSRLPLGWFT MAV_1566|M.avium_104 GIAAVSLLGLGALLGAALTLWLHVVDARFARDLRSALLRKLSRLPLGWFT MSMEG_6554|M.smegmatis_MC2_155 GVVAISLLGTGSFLAAALTLWLHLVDARFARDLRTGLLTKMSRLPLGWFT TH_2699|M.thermoresistible__bu GLTAVSLIGLGAVLAAAMTLWLHRVDARFAHELRGRLLTKLSRLPLGWFT MAB_2262c|M.abscessus_ATCC_199 GFVFLVLLVLGATLGMALTLWLHVVDLRFSADVRRRLLDKLSRVPLGWFT Mflv_2250|M.gilvum_PYR-GCK LMLALGLYLVAALMVWIQARLLNVVVQRTMVSLRADVEDKVHRLPLRYFD Mvan_4441|M.vanbaalenii_PYR-1 LALALALYLVAALMVWLQALLLNIVVQRTMVALRADVEDKVHRLPLRYFD MLBr_01113|M.leprae_Br4923 LGLALSLYLVYTLLTWAQARLLNVTVQRIMFALRSDVEDKVHRLPLSYCD : * : : : *: * :* : *: :** : MUL_3902|M.ulcerans_Agy99 GRGSGSIKQLVQDDTLSLHYLVTHAIPDAVNAVVAPVAVLVYLFIVDWRV MMAR_4037|M.marinum_M GRGSGSIKQLVQDDTLSLHYLVTHAIPDAVNAVVAPVAVLVYLFIVDWRV Mb1383|M.bovis_AF2122/97 SRGSGSIKKLVTDDTLALHYLVTHAVPDAVAAVVAPVGVLVYLFVVDWRV Rv1348|M.tuberculosis_H37Rv SRGSGSIKKLVTDDTLALHYLVTHAVPDAVAAVVAPVGVLVYLFVVDWRV MAV_1566|M.avium_104 ARGSGSIKQLLQDDTLSLHYLVTHAIPDAVAAVVAPVAVLVYLFAVDWRV MSMEG_6554|M.smegmatis_MC2_155 ARGSGSIKQLVQDDTLSLHYLITHAIPDAVAAVIAPVAVLVYLFVVDWRL TH_2699|M.thermoresistible__bu RRGSASTKQLVQDDTLALHYLITHAIPDAVAAVVAPVAVLVYLFVADWRV MAB_2262c|M.abscessus_ATCC_199 QRGSGSVKKLIQDDTMSLHYLITHSIPDAVAAVVGPVAVLVYLFVIEWRM Mflv_2250|M.gilvum_PYR-GCK SRQRGEVLSRVTNDVDNLQQSLTMSITQLLTSVLTVVAVLVMMLTISPML Mvan_4441|M.vanbaalenii_PYR-1 SRQRGEVLSRVTNDVDNLQQSLSMSITQLLTSVLTVIAVLVMMLTISPLL MLBr_01113|M.leprae_Br4923 TRQRGELLSRVTNDIDNLQSSLSITLSQLLTSLLTVVAVLVVMVSVSPLL * .. . : :* *: :: ::.: : ::: :.*** :. . : MUL_3902|M.ulcerans_Agy99 ALVLLIPVLMYLVMTSSLAVQSGSRMVASQRWAERMNDEAGAYLEGQPVI MMAR_4037|M.marinum_M ALVLLIPVLMYLVMTSSLAVQSGSRMVASQRWAERMNDEAGAYLEGQPVI Mb1383|M.bovis_AF2122/97 ALVLFGPVLVYLTITSSLTIQSGPRIVQAQRWAEKMNGEAGSYLEGQPVI Rv1348|M.tuberculosis_H37Rv ALVLFGPVLVYLTITSSLTIQSGPRIVQAQRWAEKMNGEAGSYLEGQPVI MAV_1566|M.avium_104 ALVLFVPVLVYLVLTSSLTIQSGPRIPQSQRWAETMSDEAGAYLEGQPVI MSMEG_6554|M.smegmatis_MC2_155 ALVMFVPVLIYLVLMTVMTIQSGPKIAQSQRWAERMSAEAGAYLEGQPVV TH_2699|M.thermoresistible__bu ALVLFIPVLVYLVLMSVMTIQSGSKIAQAPRWAERMGGEAGAFLEGQPVI MAB_2262c|M.abscessus_ATCC_199 ALILLIPILVYLLTMMAMMYQSGPKIVEASRWADRMSTESTAYLEGQPVI Mflv_2250|M.gilvum_PYR-GCK TLLTVVTVPLSLWVTRSIAKRSRKLFVAQWTNTGRLNAHIEETYSGFTVV Mvan_4441|M.vanbaalenii_PYR-1 TLLTVVTVPLSLWVTRSIAKRSRTLFVAQWTNTGRLNAHIEETYSGFTVV MLBr_01113|M.leprae_Br4923 ALVALLTVPMSLLATRAIAQRSQQLFVAQWTSAGRLNAHIEETYSGLTVV :*: . .: : * : :* : : :. . .* .*: MUL_3902|M.ulcerans_Agy99 RVFGGAAASSFKRQLDEYIKFLVTWQRPLVGKKTMMDLATRPSTFLWLIA MMAR_4037|M.marinum_M RVFGGAAASSFKRQLDEYIKFLVTWQRPLVGKKTMMDLATRPSTFLWLIA Mb1383|M.bovis_AF2122/97 RVFG-AASSSFRRRLDEYIGFLVAWQRPLAGKKTLMDLATRPATFLWLIA Rv1348|M.tuberculosis_H37Rv RVFG-AASSSFRRRLDEYIGFLVAWQRPLAGKKTLMDLATRPATFLWLIA MAV_1566|M.avium_104 RVFGGAAASSFRRRLDEYVGFLVAWQRPLAGKKTFMDLVTRPSTFLWLIA MSMEG_6554|M.smegmatis_MC2_155 RVFGGAAASSFRRRLDEYIGFLVAWQKPFTGKKSMMDLVTRPGTFLWLIV TH_2699|M.thermoresistible__bu RIFGGAAASRFRRRLDDYIDFLVSWQRPFVGKKTLMDLVTRPATFLWIIL MAB_2262c|M.abscessus_ATCC_199 RIFGGAAASSFKRRLDDYLRFLNDWQRPFIGRKTFMDLVTRPTTFLWLIA Mflv_2250|M.gilvum_PYR-GCK KTFGHRARAEDQFRELNDDVYHASFGAQLLSGLVSPATIFIGNLSYVAVA Mvan_4441|M.vanbaalenii_PYR-1 KTFGHRAHAEDQFRQLNDDVYHASFGAQFLSGLVSPATIFIGNLSYAAVA MLBr_01113|M.leprae_Br4923 KTFGHQTAAREQFRNVNNDVYQASFSAQFFSGLVSPATMFISNLGYVVVA : ** : : : : : : : : . : MUL_3902|M.ulcerans_Agy99 VTGTLLVINHRMDPVDLLPFLLLGTTFGVRLLGIAYGIGGISAGVLAARR MMAR_4037|M.marinum_M VTGTLLVINHRMDPVDLLPFLLLGTTFGVRLLGIAYGIGGISAGVLAARR Mb1383|M.bovis_AF2122/97 ATGTLLVATHRMDPVNLLPFMFLGTTFGARLLGIAYGLGGLRTGLLAARH Rv1348|M.tuberculosis_H37Rv ATGTLLVATHRMDPVNLLPFMFLGTTFGARLLGIAYGLGGLRTGLLAARH MAV_1566|M.avium_104 AVGTLLVVAGRMDPVNLLPFLLLGTTFGARLLGIAYGLGGIRAGMLAARR MSMEG_6554|M.smegmatis_MC2_155 AVGTPMITSGAMDPVDILPFLLLGTTFGVRLLGIAYGLGGIRGGMLAARR TH_2699|M.thermoresistible__bu VAGVPLVVTGRMDPVNLLPFLLLGTTFGARLLGIGYGLSGIQTGMLAARR MAB_2262c|M.abscessus_ATCC_199 TAGTLFVVSGAMQPVTLLPFLVLGTTFGARLLGIAYGLGSIRGGLESARH Mflv_2250|M.gilvum_PYR-GCK VVGGLQVATGQITLGGIQAFIQYVRQFNQPLTQIAGMYNTMQSGIASAER Mvan_4441|M.vanbaalenii_PYR-1 VVGGLQVATGQITLGSIQAFIQYVRQFNQPLTQIAGMYNTMQSGIASAER MLBr_01113|M.leprae_Br4923 ALGGLQVATGHITLGNIQAFIQYVRQFNMPLSQVAGIYNTLQSGLASAER . * : : : .*: *. * :. . : *: :*.: MUL_3902|M.ulcerans_Agy99 LQITLDEPVLEQHTG---------------LAEADSAAMVVFDKVSFGYR MMAR_4037|M.marinum_M LQITLDEPVLEQHTG---------------LAEADSAAMVVFDKVSFGYR Mb1383|M.bovis_AF2122/97 LQVTLDETELAVREHP------------REPLDGEAPATVVFDHVTFGYR Rv1348|M.tuberculosis_H37Rv LQVTLDETELAVREHP------------REPLDGEAPATVVFDHVTFGYR MAV_1566|M.avium_104 LQNTLDEHELEVREP--------------GEPTGESAQAVVFDNVGFGYR MSMEG_6554|M.smegmatis_MC2_155 IQTTLDETELVIREQTGKR--------------DGEP-AVVFDNVTFGYR TH_2699|M.thermoresistible__bu IQTVLDEPELVVRDRTGQAG------TDHASGDQARPGTVELDRVSFEYR MAB_2262c|M.abscessus_ATCC_199 IAVALDETELDVIEAP---------------VTADAVASVSFEGVTFGYR Mflv_2250|M.gilvum_PYR-GCK VFDLLDAEEEPADP--------VEALPASAD---RRDGRVEFDGVWFSYR Mvan_4441|M.vanbaalenii_PYR-1 VFDLLDAEEEPSEPDRRLAPDSPTVLPARDG---RPGGRVEFDRVWFGYE MLBr_01113|M.leprae_Br4923 VFDLLDEPEELPDP--------MLALPPPHGQVPRINGRVEFQQVSFAYR : ** * :: * * *. MUL_3902|M.ulcerans_Agy99 PGVPVIRDVSLQLRPGTVTALVGPSGSGKSTLAALLARFHDVEQGSIRAG MMAR_4037|M.marinum_M PGVPVIRDVSLQLRPGTVTALVGPSGSGKSTLAALLARFHDVEQGSIRVG Mb1383|M.bovis_AF2122/97 PGVPVIQDVSLTLRPGTVTALVGPSGSGKSTLATLLARFHDVERGAIRVG Rv1348|M.tuberculosis_H37Rv PGVPVIQDVSLTLRPGTVTALVGPSGSGKSTLATLLARFHDVERGAIRVG MAV_1566|M.avium_104 PDVPVIHDVSLTLRPGTLTALVGPSGSGKSTLAALLARFHDVDRGSITVG MSMEG_6554|M.smegmatis_MC2_155 PDIPVLHDISLQLTPGTVTALVGPSGSGKSTLAALLARFHDVDAGAIRLG TH_2699|M.thermoresistible__bu PGVPVIRDVTLTLRPGTVTALVGPSGSGKSTLAALVARFHDVTQGAIRVD MAB_2262c|M.abscessus_ATCC_199 PGVPVIHDVSLTLRHGTVTALVGPSGSGKSTLASLLARFHDVERGAIRID Mflv_2250|M.gilvum_PYR-GCK PGTPVVEDLSLVAEPGQTIAIVGPTGAGKTTLVNLLMRFYDVDSGRILLD Mvan_4441|M.vanbaalenii_PYR-1 HGAPVIEDLSLVAEPGTTVAIVGPTGAGKTTLVNLLMRFYDVDSGRILLD MLBr_01113|M.leprae_Br4923 TGTPVIDDLSMVVEPGSTVAIVGPTGAGKTTLVNLLMRFYDVDSGQILID . **: *::: * *:***:*:**:**. *: **:** * * . MUL_3902|M.ulcerans_Agy99 GQDIRSLSADELYERVGLVLQETQLVHGTVAENIALAVPDAPAAQIQAAA MMAR_4037|M.marinum_M GQDIRSLSADELYERVGLVLQETQLVHGTVAENIALAVPDAPAAQIQAAA Mb1383|M.bovis_AF2122/97 GQDIRSLAADELYTRVGFVLQEAQLVHGTAAENIALAVPDAPAEQVQVAA Rv1348|M.tuberculosis_H37Rv GQDIRSLAADELYTRVGFVLQEAQLVHGTAAENIALAVPDAPAEQVQVAA MAV_1566|M.avium_104 GRDIRSMTADELYARVGFVLQETQLVHGTVAENIALAVPDATAAQIEQAA MSMEG_6554|M.smegmatis_MC2_155 GRDIRTLTADELYRQVGFVLQDTQLVGGTVAENIALADPDASIERIQDAA TH_2699|M.thermoresistible__bu GRDIRTLTADELYRRVGFVLQDAQLVHGSVAENIALAEPDAGLERIRTAA MAB_2262c|M.abscessus_ATCC_199 GTDIRTLTPDELYAKVGFVFQDVQLVAGTVRENIALACPEATDDDVESAA Mflv_2250|M.gilvum_PYR-GCK GTDITTVSRGSLRSRIGMVLQDTWLFAGTIYDNIAYGRPDAAHDEVIEAA Mvan_4441|M.vanbaalenii_PYR-1 GVDISAVSRASLRSRIGMVLQDTWLFAGTVYENIAYGRPEAGRDEVIDAA MLBr_01113|M.leprae_Br4923 GVDITTVSRHALRSRIGMVLQDAWLFDGTIAENIAYGRPQASEDEVMEAA * ** ::: * ::*:*:*:. *. *: :*** . *:* : ** MUL_3902|M.ulcerans_Agy99 GQAQIHDRVLRLRDGYDTVLG-AGAALSGGERQRLTIARAILADTPVLIL MMAR_4037|M.marinum_M GQAQIHDRVLRLRDGYDTVLG-AGAALSGGERQRLTIARAILADTPVLIL Mb1383|M.bovis_AF2122/97 REAQIHDRVLRLPDGYDTVLG-ANSGLSGGERQRLTIARAILGDTPVLIL Rv1348|M.tuberculosis_H37Rv REAQIHDRVLRLPDGYDTVLG-ANSGLSGGERQRLTIARAILGDTPVLIL MAV_1566|M.avium_104 REAQIHDRIMRLPHGYDTVLG-AGVGLSGGERQRLTIARAILADTEILIL MSMEG_6554|M.smegmatis_MC2_155 RDAQIHDRIMRLPNGYDTPLG-AASSLSGGEKQRLTIARAILADTPVLIL TH_2699|M.thermoresistible__bu RDAQIHDRITRMPDGYDSVLG-AGSALSGGERQRVTIARAILADTPVLVL MAB_2262c|M.abscessus_ATCC_199 RDAQIHERILRLPNGYDTVLD-TDTQLSGGEKQRLTIARALLADTPILIL Mflv_2250|M.gilvum_PYR-GCK TAAYVDRFVHTLPDGYDTRINDGGTNISAGEKQLITIARAILARPQVLVL Mvan_4441|M.vanbaalenii_PYR-1 KAAYVDRFVHTLPDGYETRIDDGGTNISAGEKQLITIARAVLAQPQLLIL MLBr_01113|M.leprae_Br4923 KAAYVDRFVHTLSAGYQTRVSGDGDNISAGEKQLITIARAFLARPQLLIL * :. : : **:: :. :*.**:* :*****.*. . :*:* MUL_3902|M.ulcerans_Agy99 DEATAYADPESEYLVQQALNRLIKDRTVLVIAHRLHTITGADQIVVLDRG MMAR_4037|M.marinum_M DEATAYADPESEYLVQQALNRLTKDRTVLVIAHRLHTITGADQIVVLDRG Mb1383|M.bovis_AF2122/97 DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITRADQIVVLDHG Rv1348|M.tuberculosis_H37Rv DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITRADQIVVLDHG MAV_1566|M.avium_104 DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITRADQIVVLDHG MSMEG_6554|M.smegmatis_MC2_155 DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITHADQIVVLEGG TH_2699|M.thermoresistible__bu DEATAFADPESEYLVQQAINRLTRDRTVLVIAHRLHTITHADQIVVLDDG MAB_2262c|M.abscessus_ATCC_199 DEATAFADPESEYLVQQALGRLIDNRTVLVIAHRLHTIADADQIVVLDHG Mflv_2250|M.gilvum_PYR-GCK DEATSSVDTRTEVLIQHAMRELRRDRTSFIIAHRLSTIRDADTILVMEAG Mvan_4441|M.vanbaalenii_PYR-1 DEATSSVDTRTEVLIQHAMGRLRRERTSFIIAHRLSTIRDADLILVMQAG MLBr_01113|M.leprae_Br4923 DEATSSIDTRTEALIARATHDLLQDRTSFIIAHHLPTIRDADHILVVAAG ****: *..:* *: :* * :** ::***:* ** ** *:*: * MUL_3902|M.ulcerans_Agy99 QIAERGTHDELLAADGRYRRLWETGCGNQVELAAIQEGAR----- MMAR_4037|M.marinum_M QIAERGTHDELLAADGRYRRLWETGCGNQVELAAIQEGAR----- Mb1383|M.bovis_AF2122/97 RIVERGTHEELLAAGGRYCRLWDTGQGSRVAVAAAQDGTR----- Rv1348|M.tuberculosis_H37Rv RIVERGTHEELLAAGGRYCRLWDTGQGSRVAVAAAQDGTR----- MAV_1566|M.avium_104 RIVERGRHEELLAADGRYRRLWEGGRRGAVTVGTAGEVAR----- MSMEG_6554|M.smegmatis_MC2_155 RIVETGTHERLLDAAGRYRQLWETGQRPALATAAGPTGEAVR--- TH_2699|M.thermoresistible__bu RIVEVGTHDELLAAGGRYRGLWDSGRYSSPDAGRPVSADAVEVGR MAB_2262c|M.abscessus_ATCC_199 RVAETGTHTDLLANNGRYRRLWEGHRHEQSSVLAGGNL------- Mflv_2250|M.gilvum_PYR-GCK RIVERGTHSELLARRGEYWTMVNR--------------------- Mvan_4441|M.vanbaalenii_PYR-1 RIVERGTHEELLARGGEYAAMVNR--------------------- MLBr_01113|M.leprae_Br4923 KIVEQGSHAKLLARRGAYYRMTQA--------------------- ::.* * * ** * * : :