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M. avium 104 MAV_1566 (-)

annotation: putative ABC transporter ATP-binding protein
coordinates: 1523800 - 1526388
length: 862

VMLRSFGARDHTATVLETVRIAPHFVRVRMTSPTLFEDVDAEPAAWLRFWFPDPDGSKTEFQRAYTISEA
DPTAGRFAVDVVLHDPAGPASRWARTVQPGATIAVMALMGSSRFDVPDEQPAGYLLIGDSASIPGMNGII
GVVPDDVPIEMYLEQHHDDDTLIPIAVHPRLRVHWVARRDEKSLAAALESRDWSNWYAWATPEATTLKHV
RARLRDEFGFPKSEVHAQAYWSAGRAMGTRRGDESATTDGGTEAAEDIAAQVDSPQRQPEAAPVPAARGN
WRTQAAGRLLAPLRWALILSGVLQAVITLIQLAPFVLLVELVRRLVAGAPAARLWDVGIAAVSLLGLGAL
LGAALTLWLHVVDARFARDLRSALLRKLSRLPLGWFTARGSGSIKQLLQDDTLSLHYLVTHAIPDAVAAV
VAPVAVLVYLFAVDWRVALVLFVPVLVYLVLTSSLTIQSGPRIPQSQRWAETMSDEAGAYLEGQPVIRVF
GGAAASSFRRRLDEYVGFLVAWQRPLAGKKTFMDLVTRPSTFLWLIAAVGTLLVVAGRMDPVNLLPFLLL
GTTFGARLLGIAYGLGGIRAGMLAARRLQNTLDEHELEVREPGEPTGESAQAVVFDNVGFGYRPDVPVIH
DVSLTLRPGTLTALVGPSGSGKSTLAALLARFHDVDRGSITVGGRDIRSMTADELYARVGFVLQETQLVH
GTVAENIALAVPDATAAQIEQAAREAQIHDRIMRLPHGYDTVLGAGVGLSGGERQRLTIARAILADTEIL
ILDEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITRADQIVVLDHGRIVERGRHEELLAADGRY
RRLWEGGRRGAVTVGTAGEVAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1566--100% (862)putative ABC transporter ATP-binding protein
M. avium 104MAV_1420-2e-6836.28% (532) ABC transporter
M. avium 104MAV_1567-2e-5831.57% (567) ABC transporter, ATP-binding protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1383-0.079.75% (864) drugs-transport transmembrane ATP-binding protein ABC
M. gilvum PYR-GCKMflv_2250-8e-7637.09% (523) ABC transporter, transmembrane region
M. tuberculosis H37RvRv1348-0.079.75% (864) drugs-transport transmembrane ATP-binding protein ABC
M. leprae Br4923MLBr_01113-1e-6634.09% (531) putative ABC transporter, ATP-binding component
M. abscessus ATCC 19977MAB_2262c-0.065.12% (860) ABC transporter ATP-binding protein
M. marinum MMMAR_4037-0.077.85% (867) transmembrane ATP-binding protein ABC transporter
M. smegmatis MC2 155MSMEG_6554-0.073.56% (866) ABC transporter ATP-binding protein
M. thermoresistible (build 8)TH_2699-0.074.45% (548) PUTATIVE hypothetical ABC transporter ATP-binding protein
M. ulcerans Agy99MUL_3902-0.077.85% (867) transmembrane ATP-binding protein ABC transporter
M. vanbaalenii PYR-1Mvan_4441-1e-7236.62% (527) ABC transporter, transmembrane region

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4037|M.marinum_M               MARGLQGAVLRGFGARDHTATVVETVYIAPHFLRIRMVSPTLFEDAQAEP
MUL_3902|M.ulcerans_Agy99           MARGLQGAVLRGFGARDHTATVVETVYIAPHFLRIRMVSPTLFEDAQAEP
Mb1383|M.bovis_AF2122/97            MARGLQGVMLRSFGARDHTATVIETISIAPHFVRVRMVSPTLFQDAEAEP
Rv1348|M.tuberculosis_H37Rv         MARGLQGVMLRSFGARDHTATVIETISIAPHFVRVRMVSPTLFQDAEAEP
MAV_1566|M.avium_104                -------MMLRSFGARDHTATVLETVRIAPHFVRVRMTSPTLFEDVDAEP
MSMEG_6554|M.smegmatis_MC2_155      MARGIQGVMMRGFGARDHQATVVSTEAITPNLLRLRMVSPTLFEDAVAEP
TH_2699|M.thermoresistible__bu      --------------------------------------------------
MAB_2262c|M.abscessus_ATCC_199      MGRGFQGAILRGLGARDHVATVVGTAPVAPNCVRITMSAPTLFEDLLHTP
Mflv_2250|M.gilvum_PYR-GCK          ------------------------MSGPLARGIRMGEPPQERSRDFKASA
Mvan_4441|M.vanbaalenii_PYR-1       ------------------------MTGPLARSMRMAEPPQTRSRDFTGSA
MLBr_01113|M.leprae_Br4923          --------------------------------MTMATAPATRSCDFYCTI
                                                                                      

MMAR_4037|M.marinum_M               AAWLRFWFPDPKGSNTEYQRAYTLSEADAASGRFAVDVVLHEPAGPASQW
MUL_3902|M.ulcerans_Agy99           AAWLRFWFPDPKGSNTEYQRAYTLSEADAASGRFAVDVVLHEPAGPASQW
Mb1383|M.bovis_AF2122/97            AAWLRFWFPDPNGSNTEFQRAYTISEADPAAGRFAVDVVLHDPAGPASSW
Rv1348|M.tuberculosis_H37Rv         AAWLRFWFPDPNGSNTEFQRAYTISEADPAAGRFAVDVVLHDPAGPASSW
MAV_1566|M.avium_104                AAWLRFWFPDPDGSKTEFQRAYTISEADPTAGRFAVDVVLHDPAGPASRW
MSMEG_6554|M.smegmatis_MC2_155      TSWLRFWFPDPAGSKTEFQRAYTMSEMSPETGEFAIDVVLHEPAGPASRW
TH_2699|M.thermoresistible__bu      --------------------------------------------------
MAB_2262c|M.abscessus_ATCC_199      AEWLRFWFPDPDGGTSEHQRAYTIVTTDEDAGEFSIDVVIHEPAGPACQW
Mflv_2250|M.gilvum_PYR-GCK          IRLLRRLTP---------QRGMTIAVMLLGVGGIAIGVVGPRILGHATDL
Mvan_4441|M.vanbaalenii_PYR-1       LRLFRRLTP---------QRGMTVAVMLLGVGGIAIGVIGPRILGHATDL
MLBr_01113|M.leprae_Br4923          RRLLKQLVP---------QRRLSLTVITLGITGTAIGIIVPWVLGHTTDL
                                                                                      

MMAR_4037|M.marinum_M               ARTVQPGATIAVMSLMGSSSRFDVPKEQPAGYLLIGDSASIPGMNGIIGT
MUL_3902|M.ulcerans_Agy99           ARTVQPGATIAVMSLMGSSSRFDVPKEQPAGYLLIGDSASIPGMNGIIGT
Mb1383|M.bovis_AF2122/97            ARTVKPGATIAVMSLMGSS-RFDVPEEQPAGYLLIGDSASIPGMNGIIET
Rv1348|M.tuberculosis_H37Rv         ARTVKPGATIAVMSLMGSS-RFDVPEEQPAGYLLIGDSASIPGMNGIIET
MAV_1566|M.avium_104                ARTVQPGATIAVMALMGSS-RFDVPDEQPAGYLLIGDSASIPGMNGIIGV
MSMEG_6554|M.smegmatis_MC2_155      ARSAKPGDAIAVMTLGSAG--FSVPEDPPAGYLLIGDAAATPAINGIIGV
TH_2699|M.thermoresistible__bu      --------------------------------------------------
MAB_2262c|M.abscessus_ATCC_199      AVAAQPGMTIPVVAFGSAR--FEVPADLPSGFLLIGDSASIPAINSIVAA
Mflv_2250|M.gilvum_PYR-GCK          LFNGVIG-------------------------------------------
Mvan_4441|M.vanbaalenii_PYR-1       LFNGVIG-------------------------------------------
MLBr_01113|M.leprae_Br4923          LFNGVIG-------------------------------------------
                                                                                      

MMAR_4037|M.marinum_M               VPDDVPIEMYLEQHDDNDTRIPITAHSRLRVHWVRRRDETSLAEAIETRD
MUL_3902|M.ulcerans_Agy99           VPDDVPIEMYLEQHDDNDTRIPITAHPRLRVHWVPRRDETSLAEAIETRD
Mb1383|M.bovis_AF2122/97            VPNDVPIEMYLEQHDDNDTLIPLAKHPRLRVRWVMRRDEKSLAEAIENRD
Rv1348|M.tuberculosis_H37Rv         VPNDVPIEMYLEQHDDNDTLIPLAKHPRLRVRWVMRRDEKSLAEAIENRD
MAV_1566|M.avium_104                VPDDVPIEMYLEQHHDDDTLIPIAVHPRLRVHWVARRDEKSLAAALESRD
MSMEG_6554|M.smegmatis_MC2_155      VPHDIPIEVYLEEHDENDRLIPIAEHPRMRVHWVVREDATSLAGAIEARD
TH_2699|M.thermoresistible__bu      --------------------------------------------------
MAB_2262c|M.abscessus_ATCC_199      LPAEVDIEVYLERHSPDDELIPLTTHPRRRLHWVDRIDETSLAAAIEGRD
Mflv_2250|M.gilvum_PYR-GCK          ------------------RQLPAGSTKEQAIEAARARGDTTFADLLSG--
Mvan_4441|M.vanbaalenii_PYR-1       ------------------RQLPAGLTKEQAVEAARARGDGTFADLLSG--
MLBr_01113|M.leprae_Br4923          ------------------RQLPKGISKTQAVAAARTRGDNALADLLSG--
                                                                                      

MMAR_4037|M.marinum_M               WSDWYAWATPEATALKHVRKRLRDAFGFPKSVVHAQAYWTAGREMGTCRE
MUL_3902|M.ulcerans_Agy99           WSDWYAWATPEATALKHVRKRLRDAFGFPKSVVHAQAYWTAGREMGTCRE
Mb1383|M.bovis_AF2122/97            WSDWYAWATPEAAALKCVRVRLRDEFGFPKSEIHAQAYWNAGRAMGTHRA
Rv1348|M.tuberculosis_H37Rv         WSDWYAWATPEAAALKCVRVRLRDEFGFPKSEIHAQAYWNAGRAMGTHRA
MAV_1566|M.avium_104                WSNWYAWATPEATTLKHVRARLRDEFGFPKSEVHAQAYWSAGRAMGTRRG
MSMEG_6554|M.smegmatis_MC2_155      WSNWYCWVTPEAGSLKHLRTRLRDEFGFPKAELHPQAYWTEGRAMGTKRG
TH_2699|M.thermoresistible__bu      --------------------------------------------------
MAB_2262c|M.abscessus_ATCC_199      WSNWYGWASSESGSLKHLRKRLRDEFGFPKADVHAAAYWTFGRAMGSRRG
Mflv_2250|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4441|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MMAR_4037|M.marinum_M               GVPDAAAGGASTCLDDQPEVALAQAETPEPVAQSPVAATPRGSWRAQAAG
MUL_3902|M.ulcerans_Agy99           GVPDAAADGASTCLDDQPEVALAQAETPEPVAQSPVAATPRGSWRAQAAG
Mb1383|M.bovis_AF2122/97            TEPAAT----------EPEVG------AAPQPESAVPAPARGSWRAQAAS
Rv1348|M.tuberculosis_H37Rv         TEPAAT----------EPEVG------AAPQPESAVPAPARGSWRAQAAS
MAV_1566|M.avium_104                DESATTDGGTEAAEDIAAQVD-----SPQRQPEAAPVPAARGNWRTQAAG
MSMEG_6554|M.smegmatis_MC2_155      DDDKTP--------EVNPAPR------ADKPEAPAPAAAGRGNWRAQAAG
TH_2699|M.thermoresistible__bu      --------------------------------------------------
MAB_2262c|M.abscessus_ATCC_199      DSETPQ--------KATPKPVVVPTDTQVKPSATPETTAPQGRWRSQAAG
Mflv_2250|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4441|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_01113|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MMAR_4037|M.marinum_M               RLLAPLRFALILSGVLQVVATLVQLAPFVLLVELARILLSGAQESRLWHV
MUL_3902|M.ulcerans_Agy99           RLLAPLRFALILSGVLQVVATLVQLAPFVLLVELARILLSGAQESRLWHV
Mb1383|M.bovis_AF2122/97            RLLAPLKLPLVLSGVLAALVTLAQLAPFVLLVELSRLLVSGAGAHRLFTV
Rv1348|M.tuberculosis_H37Rv         RLLAPLKLPLVLSGVLAALVTLAQLAPFVLLVELSRLLVSGAGAHRLFTV
MAV_1566|M.avium_104                RLLAPLRWALILSGVLQAVITLIQLAPFVLLVELVRRLVAGAPAARLWDV
MSMEG_6554|M.smegmatis_MC2_155      RLLAPLKTTLIISGVLQAIITLVQLAPFVLLVELARLLLSGASSDRLWTL
TH_2699|M.thermoresistible__bu      ----------------------------VLLVELARLLLGGAEAERLWTL
MAB_2262c|M.abscessus_ATCC_199      ELLAPVKKQMIAGGVLQAIITMVELAPFVVLVELTRQLLAGADEAQLRHT
Mflv_2250|M.gilvum_PYR-GCK          ---------------------------------MDVVPGQGVDFAAVART
Mvan_4441|M.vanbaalenii_PYR-1       ---------------------------------MDVVPGQGVDFGAVGRT
MLBr_01113|M.leprae_Br4923          ---------------------------------MNLVPGQGVDFVAVGRT
                                                                     :      *.    :   

MMAR_4037|M.marinum_M               GLAAVSLLGLGTLLGAALTLWLHVVDARFARGLRARLLGKMSGLPLGWFT
MUL_3902|M.ulcerans_Agy99           GLAAVSLLGLGTLLGAALTLWLHVVDARFARGLRARLLGKMSGLPLGWFT
Mb1383|M.bovis_AF2122/97            GFAAVGLLGTGALLAAALTLWLHVIDARFARALRLRLLSKLSRLPLGWFT
Rv1348|M.tuberculosis_H37Rv         GFAAVGLLGTGALLAAALTLWLHVIDARFARALRLRLLSKLSRLPLGWFT
MAV_1566|M.avium_104                GIAAVSLLGLGALLGAALTLWLHVVDARFARDLRSALLRKLSRLPLGWFT
MSMEG_6554|M.smegmatis_MC2_155      GVVAISLLGTGSFLAAALTLWLHLVDARFARDLRTGLLTKMSRLPLGWFT
TH_2699|M.thermoresistible__bu      GLTAVSLIGLGAVLAAAMTLWLHRVDARFAHELRGRLLTKLSRLPLGWFT
MAB_2262c|M.abscessus_ATCC_199      GFVFLVLLVLGATLGMALTLWLHVVDLRFSADVRRRLLDKLSRVPLGWFT
Mflv_2250|M.gilvum_PYR-GCK          LMLALGLYLVAALMVWIQARLLNVVVQRTMVSLRADVEDKVHRLPLRYFD
Mvan_4441|M.vanbaalenii_PYR-1       LALALALYLVAALMVWLQALLLNIVVQRTMVALRADVEDKVHRLPLRYFD
MLBr_01113|M.leprae_Br4923          LGLALSLYLVYTLLTWAQARLLNVTVQRIMFALRSDVEDKVHRLPLSYCD
                                        : *    : :    :  *:    *    :*  :  *:  :** :  

MMAR_4037|M.marinum_M               GRGSGSIKQLVQDDTLSLHYLVTHAIPDAVNAVVAPVAVLVYLFIVDWRV
MUL_3902|M.ulcerans_Agy99           GRGSGSIKQLVQDDTLSLHYLVTHAIPDAVNAVVAPVAVLVYLFIVDWRV
Mb1383|M.bovis_AF2122/97            SRGSGSIKKLVTDDTLALHYLVTHAVPDAVAAVVAPVGVLVYLFVVDWRV
Rv1348|M.tuberculosis_H37Rv         SRGSGSIKKLVTDDTLALHYLVTHAVPDAVAAVVAPVGVLVYLFVVDWRV
MAV_1566|M.avium_104                ARGSGSIKQLLQDDTLSLHYLVTHAIPDAVAAVVAPVAVLVYLFAVDWRV
MSMEG_6554|M.smegmatis_MC2_155      ARGSGSIKQLVQDDTLSLHYLITHAIPDAVAAVIAPVAVLVYLFVVDWRL
TH_2699|M.thermoresistible__bu      RRGSASTKQLVQDDTLALHYLITHAIPDAVAAVVAPVAVLVYLFVADWRV
MAB_2262c|M.abscessus_ATCC_199      QRGSGSVKKLIQDDTMSLHYLITHSIPDAVAAVVGPVAVLVYLFVIEWRM
Mflv_2250|M.gilvum_PYR-GCK          SRQRGEVLSRVTNDVDNLQQSLTMSITQLLTSVLTVVAVLVMMLTISPML
Mvan_4441|M.vanbaalenii_PYR-1       SRQRGEVLSRVTNDVDNLQQSLSMSITQLLTSVLTVIAVLVMMLTISPLL
MLBr_01113|M.leprae_Br4923          TRQRGELLSRVTNDIDNLQSSLSITLSQLLTSLLTVVAVLVVMVSVSPLL
                                     *  ..  . : :*   *:  :: ::.: : :::  :.*** :.  .  :

MMAR_4037|M.marinum_M               ALVLLIPVLMYLVMTSSLAVQSGSRMVASQRWAERMNDEAGAYLEGQPVI
MUL_3902|M.ulcerans_Agy99           ALVLLIPVLMYLVMTSSLAVQSGSRMVASQRWAERMNDEAGAYLEGQPVI
Mb1383|M.bovis_AF2122/97            ALVLFGPVLVYLTITSSLTIQSGPRIVQAQRWAEKMNGEAGSYLEGQPVI
Rv1348|M.tuberculosis_H37Rv         ALVLFGPVLVYLTITSSLTIQSGPRIVQAQRWAEKMNGEAGSYLEGQPVI
MAV_1566|M.avium_104                ALVLFVPVLVYLVLTSSLTIQSGPRIPQSQRWAETMSDEAGAYLEGQPVI
MSMEG_6554|M.smegmatis_MC2_155      ALVMFVPVLIYLVLMTVMTIQSGPKIAQSQRWAERMSAEAGAYLEGQPVV
TH_2699|M.thermoresistible__bu      ALVLFIPVLVYLVLMSVMTIQSGSKIAQAPRWAERMGGEAGAFLEGQPVI
MAB_2262c|M.abscessus_ATCC_199      ALILLIPILVYLLTMMAMMYQSGPKIVEASRWADRMSTESTAYLEGQPVI
Mflv_2250|M.gilvum_PYR-GCK          TLLTVVTVPLSLWVTRSIAKRSRKLFVAQWTNTGRLNAHIEETYSGFTVV
Mvan_4441|M.vanbaalenii_PYR-1       TLLTVVTVPLSLWVTRSIAKRSRTLFVAQWTNTGRLNAHIEETYSGFTVV
MLBr_01113|M.leprae_Br4923          ALVALLTVPMSLLATRAIAQRSQQLFVAQWTSAGRLNAHIEETYSGLTVV
                                    :*: . .: : *     :  :*   :      :  :. .     .* .*:

MMAR_4037|M.marinum_M               RVFGGAAASSFKRQLDEYIKFLVTWQRPLVGKKTMMDLATRPSTFLWLIA
MUL_3902|M.ulcerans_Agy99           RVFGGAAASSFKRQLDEYIKFLVTWQRPLVGKKTMMDLATRPSTFLWLIA
Mb1383|M.bovis_AF2122/97            RVFG-AASSSFRRRLDEYIGFLVAWQRPLAGKKTLMDLATRPATFLWLIA
Rv1348|M.tuberculosis_H37Rv         RVFG-AASSSFRRRLDEYIGFLVAWQRPLAGKKTLMDLATRPATFLWLIA
MAV_1566|M.avium_104                RVFGGAAASSFRRRLDEYVGFLVAWQRPLAGKKTFMDLVTRPSTFLWLIA
MSMEG_6554|M.smegmatis_MC2_155      RVFGGAAASSFRRRLDEYIGFLVAWQKPFTGKKSMMDLVTRPGTFLWLIV
TH_2699|M.thermoresistible__bu      RIFGGAAASRFRRRLDDYIDFLVSWQRPFVGKKTLMDLVTRPATFLWIIL
MAB_2262c|M.abscessus_ATCC_199      RIFGGAAASSFKRRLDDYLRFLNDWQRPFIGRKTFMDLVTRPTTFLWLIA
Mflv_2250|M.gilvum_PYR-GCK          KTFGHRARAEDQFRELNDDVYHASFGAQLLSGLVSPATIFIGNLSYVAVA
Mvan_4441|M.vanbaalenii_PYR-1       KTFGHRAHAEDQFRQLNDDVYHASFGAQFLSGLVSPATIFIGNLSYAAVA
MLBr_01113|M.leprae_Br4923          KTFGHQTAAREQFRNVNNDVYQASFSAQFFSGLVSPATMFISNLGYVVVA
                                    : **  : :  : :  :   :   :   : .                 : 

MMAR_4037|M.marinum_M               VTGTLLVINHRMDPVDLLPFLLLGTTFGVRLLGIAYGIGGISAGVLAARR
MUL_3902|M.ulcerans_Agy99           VTGTLLVINHRMDPVDLLPFLLLGTTFGVRLLGIAYGIGGISAGVLAARR
Mb1383|M.bovis_AF2122/97            ATGTLLVATHRMDPVNLLPFMFLGTTFGARLLGIAYGLGGLRTGLLAARH
Rv1348|M.tuberculosis_H37Rv         ATGTLLVATHRMDPVNLLPFMFLGTTFGARLLGIAYGLGGLRTGLLAARH
MAV_1566|M.avium_104                AVGTLLVVAGRMDPVNLLPFLLLGTTFGARLLGIAYGLGGIRAGMLAARR
MSMEG_6554|M.smegmatis_MC2_155      AVGTPMITSGAMDPVDILPFLLLGTTFGVRLLGIAYGLGGIRGGMLAARR
TH_2699|M.thermoresistible__bu      VAGVPLVVTGRMDPVNLLPFLLLGTTFGARLLGIGYGLSGIQTGMLAARR
MAB_2262c|M.abscessus_ATCC_199      TAGTLFVVSGAMQPVTLLPFLVLGTTFGARLLGIAYGLGSIRGGLESARH
Mflv_2250|M.gilvum_PYR-GCK          VVGGLQVATGQITLGGIQAFIQYVRQFNQPLTQIAGMYNTMQSGIASAER
Mvan_4441|M.vanbaalenii_PYR-1       VVGGLQVATGQITLGSIQAFIQYVRQFNQPLTQIAGMYNTMQSGIASAER
MLBr_01113|M.leprae_Br4923          ALGGLQVATGHITLGNIQAFIQYVRQFNMPLSQVAGIYNTLQSGLASAER
                                    . *   :    :    : .*:     *.  *  :.   . :  *: :*.:

MMAR_4037|M.marinum_M               LQITLDEPVLEQHTG---------------LAEADSAAMVVFDKVSFGYR
MUL_3902|M.ulcerans_Agy99           LQITLDEPVLEQHTG---------------LAEADSAAMVVFDKVSFGYR
Mb1383|M.bovis_AF2122/97            LQVTLDETELAVREHP------------REPLDGEAPATVVFDHVTFGYR
Rv1348|M.tuberculosis_H37Rv         LQVTLDETELAVREHP------------REPLDGEAPATVVFDHVTFGYR
MAV_1566|M.avium_104                LQNTLDEHELEVREP--------------GEPTGESAQAVVFDNVGFGYR
MSMEG_6554|M.smegmatis_MC2_155      IQTTLDETELVIREQTGKR--------------DGEP-AVVFDNVTFGYR
TH_2699|M.thermoresistible__bu      IQTVLDEPELVVRDRTGQAG------TDHASGDQARPGTVELDRVSFEYR
MAB_2262c|M.abscessus_ATCC_199      IAVALDETELDVIEAP---------------VTADAVASVSFEGVTFGYR
Mflv_2250|M.gilvum_PYR-GCK          VFDLLDAEEEPADP--------VEALPASAD---RRDGRVEFDGVWFSYR
Mvan_4441|M.vanbaalenii_PYR-1       VFDLLDAEEEPSEPDRRLAPDSPTVLPARDG---RPGGRVEFDRVWFGYE
MLBr_01113|M.leprae_Br4923          VFDLLDEPEELPDP--------MLALPPPHGQVPRINGRVEFQQVSFAYR
                                    :   **                                 * :: * * *.

MMAR_4037|M.marinum_M               PGVPVIRDVSLQLRPGTVTALVGPSGSGKSTLAALLARFHDVEQGSIRVG
MUL_3902|M.ulcerans_Agy99           PGVPVIRDVSLQLRPGTVTALVGPSGSGKSTLAALLARFHDVEQGSIRAG
Mb1383|M.bovis_AF2122/97            PGVPVIQDVSLTLRPGTVTALVGPSGSGKSTLATLLARFHDVERGAIRVG
Rv1348|M.tuberculosis_H37Rv         PGVPVIQDVSLTLRPGTVTALVGPSGSGKSTLATLLARFHDVERGAIRVG
MAV_1566|M.avium_104                PDVPVIHDVSLTLRPGTLTALVGPSGSGKSTLAALLARFHDVDRGSITVG
MSMEG_6554|M.smegmatis_MC2_155      PDIPVLHDISLQLTPGTVTALVGPSGSGKSTLAALLARFHDVDAGAIRLG
TH_2699|M.thermoresistible__bu      PGVPVIRDVTLTLRPGTVTALVGPSGSGKSTLAALVARFHDVTQGAIRVD
MAB_2262c|M.abscessus_ATCC_199      PGVPVIHDVSLTLRHGTVTALVGPSGSGKSTLASLLARFHDVERGAIRID
Mflv_2250|M.gilvum_PYR-GCK          PGTPVVEDLSLVAEPGQTIAIVGPTGAGKTTLVNLLMRFYDVDSGRILLD
Mvan_4441|M.vanbaalenii_PYR-1       HGAPVIEDLSLVAEPGTTVAIVGPTGAGKTTLVNLLMRFYDVDSGRILLD
MLBr_01113|M.leprae_Br4923          TGTPVIDDLSMVVEPGSTVAIVGPTGAGKTTLVNLLMRFYDVDSGQILID
                                     . **: *:::    *   *:***:*:**:**. *: **:**  * *  .

MMAR_4037|M.marinum_M               GQDIRSLSADELYERVGLVLQETQLVHGTVAENIALAVPDAPAAQIQAAA
MUL_3902|M.ulcerans_Agy99           GQDIRSLSADELYERVGLVLQETQLVHGTVAENIALAVPDAPAAQIQAAA
Mb1383|M.bovis_AF2122/97            GQDIRSLAADELYTRVGFVLQEAQLVHGTAAENIALAVPDAPAEQVQVAA
Rv1348|M.tuberculosis_H37Rv         GQDIRSLAADELYTRVGFVLQEAQLVHGTAAENIALAVPDAPAEQVQVAA
MAV_1566|M.avium_104                GRDIRSMTADELYARVGFVLQETQLVHGTVAENIALAVPDATAAQIEQAA
MSMEG_6554|M.smegmatis_MC2_155      GRDIRTLTADELYRQVGFVLQDTQLVGGTVAENIALADPDASIERIQDAA
TH_2699|M.thermoresistible__bu      GRDIRTLTADELYRRVGFVLQDAQLVHGSVAENIALAEPDAGLERIRTAA
MAB_2262c|M.abscessus_ATCC_199      GTDIRTLTPDELYAKVGFVFQDVQLVAGTVRENIALACPEATDDDVESAA
Mflv_2250|M.gilvum_PYR-GCK          GTDITTVSRGSLRSRIGMVLQDTWLFAGTIYDNIAYGRPDAAHDEVIEAA
Mvan_4441|M.vanbaalenii_PYR-1       GVDISAVSRASLRSRIGMVLQDTWLFAGTVYENIAYGRPEAGRDEVIDAA
MLBr_01113|M.leprae_Br4923          GVDITTVSRHALRSRIGMVLQDAWLFDGTIAENIAYGRPQASEDEVMEAA
                                    * ** :::   *  ::*:*:*:. *. *:  :*** . *:*    :  **

MMAR_4037|M.marinum_M               GQAQIHDRVLRLRDGYDTVLG-AGAALSGGERQRLTIARAILADTPVLIL
MUL_3902|M.ulcerans_Agy99           GQAQIHDRVLRLRDGYDTVLG-AGAALSGGERQRLTIARAILADTPVLIL
Mb1383|M.bovis_AF2122/97            REAQIHDRVLRLPDGYDTVLG-ANSGLSGGERQRLTIARAILGDTPVLIL
Rv1348|M.tuberculosis_H37Rv         REAQIHDRVLRLPDGYDTVLG-ANSGLSGGERQRLTIARAILGDTPVLIL
MAV_1566|M.avium_104                REAQIHDRIMRLPHGYDTVLG-AGVGLSGGERQRLTIARAILADTEILIL
MSMEG_6554|M.smegmatis_MC2_155      RDAQIHDRIMRLPNGYDTPLG-AASSLSGGEKQRLTIARAILADTPVLIL
TH_2699|M.thermoresistible__bu      RDAQIHDRITRMPDGYDSVLG-AGSALSGGERQRVTIARAILADTPVLVL
MAB_2262c|M.abscessus_ATCC_199      RDAQIHERILRLPNGYDTVLD-TDTQLSGGEKQRLTIARALLADTPILIL
Mflv_2250|M.gilvum_PYR-GCK          TAAYVDRFVHTLPDGYDTRINDGGTNISAGEKQLITIARAILARPQVLVL
Mvan_4441|M.vanbaalenii_PYR-1       KAAYVDRFVHTLPDGYETRIDDGGTNISAGEKQLITIARAVLAQPQLLIL
MLBr_01113|M.leprae_Br4923          KAAYVDRFVHTLSAGYQTRVSGDGDNISAGEKQLITIARAFLARPQLLIL
                                      * :.  :  :  **:: :.     :*.**:* :*****.*. . :*:*

MMAR_4037|M.marinum_M               DEATAYADPESEYLVQQALNRLTKDRTVLVIAHRLHTITGADQIVVLDRG
MUL_3902|M.ulcerans_Agy99           DEATAYADPESEYLVQQALNRLIKDRTVLVIAHRLHTITGADQIVVLDRG
Mb1383|M.bovis_AF2122/97            DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITRADQIVVLDHG
Rv1348|M.tuberculosis_H37Rv         DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITRADQIVVLDHG
MAV_1566|M.avium_104                DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITRADQIVVLDHG
MSMEG_6554|M.smegmatis_MC2_155      DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITHADQIVVLEGG
TH_2699|M.thermoresistible__bu      DEATAFADPESEYLVQQAINRLTRDRTVLVIAHRLHTITHADQIVVLDDG
MAB_2262c|M.abscessus_ATCC_199      DEATAFADPESEYLVQQALGRLIDNRTVLVIAHRLHTIADADQIVVLDHG
Mflv_2250|M.gilvum_PYR-GCK          DEATSSVDTRTEVLIQHAMRELRRDRTSFIIAHRLSTIRDADTILVMEAG
Mvan_4441|M.vanbaalenii_PYR-1       DEATSSVDTRTEVLIQHAMGRLRRERTSFIIAHRLSTIRDADLILVMQAG
MLBr_01113|M.leprae_Br4923          DEATSSIDTRTEALIARATHDLLQDRTSFIIAHHLPTIRDADHILVVAAG
                                    ****:  *..:* *: :*   *  :** ::***:* **  ** *:*:  *

MMAR_4037|M.marinum_M               QIAERGTHDELLAADGRYRRLWETGCGNQVELAAIQEGAR-----
MUL_3902|M.ulcerans_Agy99           QIAERGTHDELLAADGRYRRLWETGCGNQVELAAIQEGAR-----
Mb1383|M.bovis_AF2122/97            RIVERGTHEELLAAGGRYCRLWDTGQGSRVAVAAAQDGTR-----
Rv1348|M.tuberculosis_H37Rv         RIVERGTHEELLAAGGRYCRLWDTGQGSRVAVAAAQDGTR-----
MAV_1566|M.avium_104                RIVERGRHEELLAADGRYRRLWEGGRRGAVTVGTAGEVAR-----
MSMEG_6554|M.smegmatis_MC2_155      RIVETGTHERLLDAAGRYRQLWETGQRPALATAAGPTGEAVR---
TH_2699|M.thermoresistible__bu      RIVEVGTHDELLAAGGRYRGLWDSGRYSSPDAGRPVSADAVEVGR
MAB_2262c|M.abscessus_ATCC_199      RVAETGTHTDLLANNGRYRRLWEGHRHEQSSVLAGGNL-------
Mflv_2250|M.gilvum_PYR-GCK          RIVERGTHSELLARRGEYWTMVNR---------------------
Mvan_4441|M.vanbaalenii_PYR-1       RIVERGTHEELLARGGEYAAMVNR---------------------
MLBr_01113|M.leprae_Br4923          KIVEQGSHAKLLARRGAYYRMTQA---------------------
                                    ::.* * *  **   * *  : :