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ARGIQGVMMRGFGARDHQATVVSTEAITPNLLRLRMVSPTLFEDAVAEPTSWLRFWFPDPAGSKTEFQRA YTMSEMSPETGEFAIDVVLHEPAGPASRWARSAKPGDAIAVMTLGSAGFSVPEDPPAGYLLIGDAAATPA INGIIGVVPHDIPIEVYLEEHDENDRLIPIAEHPRMRVHWVVREDATSLAGAIEARDWSNWYCWVTPEAG SLKHLRTRLRDEFGFPKAELHPQAYWTEGRAMGTKRGDDDKTPEVNPAPRADKPEAPAPAAAGRGNWRAQ AAGRLLAPLKTTLIISGVLQAIITLVQLAPFVLLVELARLLLSGASSDRLWTLGVVAISLLGTGSFLAAA LTLWLHLVDARFARDLRTGLLTKMSRLPLGWFTARGSGSIKQLVQDDTLSLHYLITHAIPDAVAAVIAPV AVLVYLFVVDWRLALVMFVPVLIYLVLMTVMTIQSGPKIAQSQRWAERMSAEAGAYLEGQPVVRVFGGAA ASSFRRRLDEYIGFLVAWQKPFTGKKSMMDLVTRPGTFLWLIVAVGTPMITSGAMDPVDILPFLLLGTTF GVRLLGIAYGLGGIRGGMLAARRIQTTLDETELVIREQTGKRDGEPAVVFDNVTFGYRPDIPVLHDISLQ LTPGTVTALVGPSGSGKSTLAALLARFHDVDAGAIRLGGRDIRTLTADELYRQVGFVLQDTQLVGGTVAE NIALADPDASIERIQDAARDAQIHDRIMRLPNGYDTPLGAASSLSGGEKQRLTIARAILADTPVLILDEA TAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITHADQIVVLEGGRIVETGTHERLLDAAGRYRQLWE TGQRPALATAAGPTGEAVR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6554 | - | - | 100% (860) | ABC transporter ATP-binding protein |
M. smegmatis MC2 155 | MSMEG_5009 | - | 6e-71 | 35.21% (514) | ABC transporter |
M. smegmatis MC2 155 | MSMEG_5661 | - | 7e-66 | 32.37% (621) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1383 | - | 0.0 | 71.69% (862) | drugs-transport transmembrane ATP-binding protein ABC |
M. gilvum PYR-GCK | Mflv_2250 | - | 3e-74 | 36.50% (515) | ABC transporter, transmembrane region |
M. tuberculosis H37Rv | Rv1348 | - | 0.0 | 71.69% (862) | drugs-transport transmembrane ATP-binding protein ABC |
M. leprae Br4923 | MLBr_01113 | - | 9e-64 | 33.40% (524) | putative ABC transporter, ATP-binding component |
M. abscessus ATCC 19977 | MAB_2262c | - | 0.0 | 64.03% (859) | ABC transporter ATP-binding protein |
M. marinum M | MMAR_4037 | - | 0.0 | 70.53% (862) | transmembrane ATP-binding protein ABC transporter |
M. avium 104 | MAV_1566 | - | 0.0 | 73.56% (866) | putative ABC transporter ATP-binding protein |
M. thermoresistible (build 8) | TH_2699 | - | 0.0 | 75.60% (541) | PUTATIVE hypothetical ABC transporter ATP-binding protein |
M. ulcerans Agy99 | MUL_3902 | - | 0.0 | 70.53% (862) | transmembrane ATP-binding protein ABC transporter |
M. vanbaalenii PYR-1 | Mvan_4441 | - | 2e-71 | 35.96% (520) | ABC transporter, transmembrane region |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_6554|M.smegmatis_MC2_155 MARGIQGVMMRGFGARDHQATVVSTEAITPNLLRLRMVSPTLFEDAVAEP TH_2699|M.thermoresistible__bu -------------------------------------------------- Mb1383|M.bovis_AF2122/97 MARGLQGVMLRSFGARDHTATVIETISIAPHFVRVRMVSPTLFQDAEAEP Rv1348|M.tuberculosis_H37Rv MARGLQGVMLRSFGARDHTATVIETISIAPHFVRVRMVSPTLFQDAEAEP MMAR_4037|M.marinum_M MARGLQGAVLRGFGARDHTATVVETVYIAPHFLRIRMVSPTLFEDAQAEP MUL_3902|M.ulcerans_Agy99 MARGLQGAVLRGFGARDHTATVVETVYIAPHFLRIRMVSPTLFEDAQAEP MAV_1566|M.avium_104 -------MMLRSFGARDHTATVLETVRIAPHFVRVRMTSPTLFEDVDAEP MAB_2262c|M.abscessus_ATCC_199 MGRGFQGAILRGLGARDHVATVVGTAPVAPNCVRITMSAPTLFEDLLHTP Mflv_2250|M.gilvum_PYR-GCK ------------------------MSGPLARGIRMGEPPQERSRDFKASA Mvan_4441|M.vanbaalenii_PYR-1 ------------------------MTGPLARSMRMAEPPQTRSRDFTGSA MLBr_01113|M.leprae_Br4923 --------------------------------MTMATAPATRSCDFYCTI MSMEG_6554|M.smegmatis_MC2_155 TSWLRFWFPDPAGSKTEFQRAYTMSEMSPETGEFAIDVVLHEPAGPASRW TH_2699|M.thermoresistible__bu -------------------------------------------------- Mb1383|M.bovis_AF2122/97 AAWLRFWFPDPNGSNTEFQRAYTISEADPAAGRFAVDVVLHDPAGPASSW Rv1348|M.tuberculosis_H37Rv AAWLRFWFPDPNGSNTEFQRAYTISEADPAAGRFAVDVVLHDPAGPASSW MMAR_4037|M.marinum_M AAWLRFWFPDPKGSNTEYQRAYTLSEADAASGRFAVDVVLHEPAGPASQW MUL_3902|M.ulcerans_Agy99 AAWLRFWFPDPKGSNTEYQRAYTLSEADAASGRFAVDVVLHEPAGPASQW MAV_1566|M.avium_104 AAWLRFWFPDPDGSKTEFQRAYTISEADPTAGRFAVDVVLHDPAGPASRW MAB_2262c|M.abscessus_ATCC_199 AEWLRFWFPDPDGGTSEHQRAYTIVTTDEDAGEFSIDVVIHEPAGPACQW Mflv_2250|M.gilvum_PYR-GCK IRLLRRLTP---------QRGMTIAVMLLGVGGIAIGVVGPRILGHATDL Mvan_4441|M.vanbaalenii_PYR-1 LRLFRRLTP---------QRGMTVAVMLLGVGGIAIGVIGPRILGHATDL MLBr_01113|M.leprae_Br4923 RRLLKQLVP---------QRRLSLTVITLGITGTAIGIIVPWVLGHTTDL MSMEG_6554|M.smegmatis_MC2_155 ARSAKPGDAIAVMTLGSAG--FSVPEDPPAGYLLIGDAAATPAINGIIGV TH_2699|M.thermoresistible__bu -------------------------------------------------- Mb1383|M.bovis_AF2122/97 ARTVKPGATIAVMSLMGSS-RFDVPEEQPAGYLLIGDSASIPGMNGIIET Rv1348|M.tuberculosis_H37Rv ARTVKPGATIAVMSLMGSS-RFDVPEEQPAGYLLIGDSASIPGMNGIIET MMAR_4037|M.marinum_M ARTVQPGATIAVMSLMGSSSRFDVPKEQPAGYLLIGDSASIPGMNGIIGT MUL_3902|M.ulcerans_Agy99 ARTVQPGATIAVMSLMGSSSRFDVPKEQPAGYLLIGDSASIPGMNGIIGT MAV_1566|M.avium_104 ARTVQPGATIAVMALMGSS-RFDVPDEQPAGYLLIGDSASIPGMNGIIGV MAB_2262c|M.abscessus_ATCC_199 AVAAQPGMTIPVVAFGSAR--FEVPADLPSGFLLIGDSASIPAINSIVAA Mflv_2250|M.gilvum_PYR-GCK LFNGVIG------------------------------------------- Mvan_4441|M.vanbaalenii_PYR-1 LFNGVIG------------------------------------------- MLBr_01113|M.leprae_Br4923 LFNGVIG------------------------------------------- MSMEG_6554|M.smegmatis_MC2_155 VPHDIPIEVYLEEHDENDRLIPIAEHPRMRVHWVVREDATSLAGAIEARD TH_2699|M.thermoresistible__bu -------------------------------------------------- Mb1383|M.bovis_AF2122/97 VPNDVPIEMYLEQHDDNDTLIPLAKHPRLRVRWVMRRDEKSLAEAIENRD Rv1348|M.tuberculosis_H37Rv VPNDVPIEMYLEQHDDNDTLIPLAKHPRLRVRWVMRRDEKSLAEAIENRD MMAR_4037|M.marinum_M VPDDVPIEMYLEQHDDNDTRIPITAHSRLRVHWVRRRDETSLAEAIETRD MUL_3902|M.ulcerans_Agy99 VPDDVPIEMYLEQHDDNDTRIPITAHPRLRVHWVPRRDETSLAEAIETRD MAV_1566|M.avium_104 VPDDVPIEMYLEQHHDDDTLIPIAVHPRLRVHWVARRDEKSLAAALESRD MAB_2262c|M.abscessus_ATCC_199 LPAEVDIEVYLERHSPDDELIPLTTHPRRRLHWVDRIDETSLAAAIEGRD Mflv_2250|M.gilvum_PYR-GCK ------------------RQLPAGSTKEQAIEAARARGDTTFADLLSG-- Mvan_4441|M.vanbaalenii_PYR-1 ------------------RQLPAGLTKEQAVEAARARGDGTFADLLSG-- MLBr_01113|M.leprae_Br4923 ------------------RQLPKGISKTQAVAAARTRGDNALADLLSG-- MSMEG_6554|M.smegmatis_MC2_155 WSNWYCWVTPEAGSLKHLRTRLRDEFGFPKAELHPQAYWTEGRAMGTKRG TH_2699|M.thermoresistible__bu -------------------------------------------------- Mb1383|M.bovis_AF2122/97 WSDWYAWATPEAAALKCVRVRLRDEFGFPKSEIHAQAYWNAGRAMGTHRA Rv1348|M.tuberculosis_H37Rv WSDWYAWATPEAAALKCVRVRLRDEFGFPKSEIHAQAYWNAGRAMGTHRA MMAR_4037|M.marinum_M WSDWYAWATPEATALKHVRKRLRDAFGFPKSVVHAQAYWTAGREMGTCRE MUL_3902|M.ulcerans_Agy99 WSDWYAWATPEATALKHVRKRLRDAFGFPKSVVHAQAYWTAGREMGTCRE MAV_1566|M.avium_104 WSNWYAWATPEATTLKHVRARLRDEFGFPKSEVHAQAYWSAGRAMGTRRG MAB_2262c|M.abscessus_ATCC_199 WSNWYGWASSESGSLKHLRKRLRDEFGFPKADVHAAAYWTFGRAMGSRRG Mflv_2250|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4441|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MSMEG_6554|M.smegmatis_MC2_155 DDDKTP--------EVNPAPR------ADKPEAPAPAAAGRGNWRAQAAG TH_2699|M.thermoresistible__bu -------------------------------------------------- Mb1383|M.bovis_AF2122/97 TEPAAT----------EPEVG------AAPQPESAVPAPARGSWRAQAAS Rv1348|M.tuberculosis_H37Rv TEPAAT----------EPEVG------AAPQPESAVPAPARGSWRAQAAS MMAR_4037|M.marinum_M GVPDAAAGGASTCLDDQPEVALAQAETPEPVAQSPVAATPRGSWRAQAAG MUL_3902|M.ulcerans_Agy99 GVPDAAADGASTCLDDQPEVALAQAETPEPVAQSPVAATPRGSWRAQAAG MAV_1566|M.avium_104 DESATTDGGTEAAEDIAAQVD-----SPQRQPEAAPVPAARGNWRTQAAG MAB_2262c|M.abscessus_ATCC_199 DSETPQ--------KATPKPVVVPTDTQVKPSATPETTAPQGRWRSQAAG Mflv_2250|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4441|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MSMEG_6554|M.smegmatis_MC2_155 RLLAPLKTTLIISGVLQAIITLVQLAPFVLLVELARLLLSGASSDRLWTL TH_2699|M.thermoresistible__bu ----------------------------VLLVELARLLLGGAEAERLWTL Mb1383|M.bovis_AF2122/97 RLLAPLKLPLVLSGVLAALVTLAQLAPFVLLVELSRLLVSGAGAHRLFTV Rv1348|M.tuberculosis_H37Rv RLLAPLKLPLVLSGVLAALVTLAQLAPFVLLVELSRLLVSGAGAHRLFTV MMAR_4037|M.marinum_M RLLAPLRFALILSGVLQVVATLVQLAPFVLLVELARILLSGAQESRLWHV MUL_3902|M.ulcerans_Agy99 RLLAPLRFALILSGVLQVVATLVQLAPFVLLVELARILLSGAQESRLWHV MAV_1566|M.avium_104 RLLAPLRWALILSGVLQAVITLIQLAPFVLLVELVRRLVAGAPAARLWDV MAB_2262c|M.abscessus_ATCC_199 ELLAPVKKQMIAGGVLQAIITMVELAPFVVLVELTRQLLAGADEAQLRHT Mflv_2250|M.gilvum_PYR-GCK ---------------------------------MDVVPGQGVDFAAVART Mvan_4441|M.vanbaalenii_PYR-1 ---------------------------------MDVVPGQGVDFGAVGRT MLBr_01113|M.leprae_Br4923 ---------------------------------MNLVPGQGVDFVAVGRT : *. : MSMEG_6554|M.smegmatis_MC2_155 GVVAISLLGTGSFLAAALTLWLHLVDARFARDLRTGLLTKMSRLPLGWFT TH_2699|M.thermoresistible__bu GLTAVSLIGLGAVLAAAMTLWLHRVDARFAHELRGRLLTKLSRLPLGWFT Mb1383|M.bovis_AF2122/97 GFAAVGLLGTGALLAAALTLWLHVIDARFARALRLRLLSKLSRLPLGWFT Rv1348|M.tuberculosis_H37Rv GFAAVGLLGTGALLAAALTLWLHVIDARFARALRLRLLSKLSRLPLGWFT MMAR_4037|M.marinum_M GLAAVSLLGLGTLLGAALTLWLHVVDARFARGLRARLLGKMSGLPLGWFT MUL_3902|M.ulcerans_Agy99 GLAAVSLLGLGTLLGAALTLWLHVVDARFARGLRARLLGKMSGLPLGWFT MAV_1566|M.avium_104 GIAAVSLLGLGALLGAALTLWLHVVDARFARDLRSALLRKLSRLPLGWFT MAB_2262c|M.abscessus_ATCC_199 GFVFLVLLVLGATLGMALTLWLHVVDLRFSADVRRRLLDKLSRVPLGWFT Mflv_2250|M.gilvum_PYR-GCK LMLALGLYLVAALMVWIQARLLNVVVQRTMVSLRADVEDKVHRLPLRYFD Mvan_4441|M.vanbaalenii_PYR-1 LALALALYLVAALMVWLQALLLNIVVQRTMVALRADVEDKVHRLPLRYFD MLBr_01113|M.leprae_Br4923 LGLALSLYLVYTLLTWAQARLLNVTVQRIMFALRSDVEDKVHRLPLSYCD : * : : : *: * :* : *: :** : MSMEG_6554|M.smegmatis_MC2_155 ARGSGSIKQLVQDDTLSLHYLITHAIPDAVAAVIAPVAVLVYLFVVDWRL TH_2699|M.thermoresistible__bu RRGSASTKQLVQDDTLALHYLITHAIPDAVAAVVAPVAVLVYLFVADWRV Mb1383|M.bovis_AF2122/97 SRGSGSIKKLVTDDTLALHYLVTHAVPDAVAAVVAPVGVLVYLFVVDWRV Rv1348|M.tuberculosis_H37Rv SRGSGSIKKLVTDDTLALHYLVTHAVPDAVAAVVAPVGVLVYLFVVDWRV MMAR_4037|M.marinum_M GRGSGSIKQLVQDDTLSLHYLVTHAIPDAVNAVVAPVAVLVYLFIVDWRV MUL_3902|M.ulcerans_Agy99 GRGSGSIKQLVQDDTLSLHYLVTHAIPDAVNAVVAPVAVLVYLFIVDWRV MAV_1566|M.avium_104 ARGSGSIKQLLQDDTLSLHYLVTHAIPDAVAAVVAPVAVLVYLFAVDWRV MAB_2262c|M.abscessus_ATCC_199 QRGSGSVKKLIQDDTMSLHYLITHSIPDAVAAVVGPVAVLVYLFVIEWRM Mflv_2250|M.gilvum_PYR-GCK SRQRGEVLSRVTNDVDNLQQSLTMSITQLLTSVLTVVAVLVMMLTISPML Mvan_4441|M.vanbaalenii_PYR-1 SRQRGEVLSRVTNDVDNLQQSLSMSITQLLTSVLTVIAVLVMMLTISPLL MLBr_01113|M.leprae_Br4923 TRQRGELLSRVTNDIDNLQSSLSITLSQLLTSLLTVVAVLVVMVSVSPLL * .. . : :* *: :: ::.: : ::: :.*** :. . : MSMEG_6554|M.smegmatis_MC2_155 ALVMFVPVLIYLVLMTVMTIQSGPKIAQSQRWAERMSAEAGAYLEGQPVV TH_2699|M.thermoresistible__bu ALVLFIPVLVYLVLMSVMTIQSGSKIAQAPRWAERMGGEAGAFLEGQPVI Mb1383|M.bovis_AF2122/97 ALVLFGPVLVYLTITSSLTIQSGPRIVQAQRWAEKMNGEAGSYLEGQPVI Rv1348|M.tuberculosis_H37Rv ALVLFGPVLVYLTITSSLTIQSGPRIVQAQRWAEKMNGEAGSYLEGQPVI MMAR_4037|M.marinum_M ALVLLIPVLMYLVMTSSLAVQSGSRMVASQRWAERMNDEAGAYLEGQPVI MUL_3902|M.ulcerans_Agy99 ALVLLIPVLMYLVMTSSLAVQSGSRMVASQRWAERMNDEAGAYLEGQPVI MAV_1566|M.avium_104 ALVLFVPVLVYLVLTSSLTIQSGPRIPQSQRWAETMSDEAGAYLEGQPVI MAB_2262c|M.abscessus_ATCC_199 ALILLIPILVYLLTMMAMMYQSGPKIVEASRWADRMSTESTAYLEGQPVI Mflv_2250|M.gilvum_PYR-GCK TLLTVVTVPLSLWVTRSIAKRSRKLFVAQWTNTGRLNAHIEETYSGFTVV Mvan_4441|M.vanbaalenii_PYR-1 TLLTVVTVPLSLWVTRSIAKRSRTLFVAQWTNTGRLNAHIEETYSGFTVV MLBr_01113|M.leprae_Br4923 ALVALLTVPMSLLATRAIAQRSQQLFVAQWTSAGRLNAHIEETYSGLTVV :*: . .: : * : :* : : :. . .* .*: MSMEG_6554|M.smegmatis_MC2_155 RVFGGAAASSFRRRLDEYIGFLVAWQKPFTGKKSMMDLVTRPGTFLWLIV TH_2699|M.thermoresistible__bu RIFGGAAASRFRRRLDDYIDFLVSWQRPFVGKKTLMDLVTRPATFLWIIL Mb1383|M.bovis_AF2122/97 RVFG-AASSSFRRRLDEYIGFLVAWQRPLAGKKTLMDLATRPATFLWLIA Rv1348|M.tuberculosis_H37Rv RVFG-AASSSFRRRLDEYIGFLVAWQRPLAGKKTLMDLATRPATFLWLIA MMAR_4037|M.marinum_M RVFGGAAASSFKRQLDEYIKFLVTWQRPLVGKKTMMDLATRPSTFLWLIA MUL_3902|M.ulcerans_Agy99 RVFGGAAASSFKRQLDEYIKFLVTWQRPLVGKKTMMDLATRPSTFLWLIA MAV_1566|M.avium_104 RVFGGAAASSFRRRLDEYVGFLVAWQRPLAGKKTFMDLVTRPSTFLWLIA MAB_2262c|M.abscessus_ATCC_199 RIFGGAAASSFKRRLDDYLRFLNDWQRPFIGRKTFMDLVTRPTTFLWLIA Mflv_2250|M.gilvum_PYR-GCK KTFGHRARAEDQFRELNDDVYHASFGAQLLSGLVSPATIFIGNLSYVAVA Mvan_4441|M.vanbaalenii_PYR-1 KTFGHRAHAEDQFRQLNDDVYHASFGAQFLSGLVSPATIFIGNLSYAAVA MLBr_01113|M.leprae_Br4923 KTFGHQTAAREQFRNVNNDVYQASFSAQFFSGLVSPATMFISNLGYVVVA : ** : : : : : : : : . : MSMEG_6554|M.smegmatis_MC2_155 AVGTPMITSGAMDPVDILPFLLLGTTFGVRLLGIAYGLGGIRGGMLAARR TH_2699|M.thermoresistible__bu VAGVPLVVTGRMDPVNLLPFLLLGTTFGARLLGIGYGLSGIQTGMLAARR Mb1383|M.bovis_AF2122/97 ATGTLLVATHRMDPVNLLPFMFLGTTFGARLLGIAYGLGGLRTGLLAARH Rv1348|M.tuberculosis_H37Rv ATGTLLVATHRMDPVNLLPFMFLGTTFGARLLGIAYGLGGLRTGLLAARH MMAR_4037|M.marinum_M VTGTLLVINHRMDPVDLLPFLLLGTTFGVRLLGIAYGIGGISAGVLAARR MUL_3902|M.ulcerans_Agy99 VTGTLLVINHRMDPVDLLPFLLLGTTFGVRLLGIAYGIGGISAGVLAARR MAV_1566|M.avium_104 AVGTLLVVAGRMDPVNLLPFLLLGTTFGARLLGIAYGLGGIRAGMLAARR MAB_2262c|M.abscessus_ATCC_199 TAGTLFVVSGAMQPVTLLPFLVLGTTFGARLLGIAYGLGSIRGGLESARH Mflv_2250|M.gilvum_PYR-GCK VVGGLQVATGQITLGGIQAFIQYVRQFNQPLTQIAGMYNTMQSGIASAER Mvan_4441|M.vanbaalenii_PYR-1 VVGGLQVATGQITLGSIQAFIQYVRQFNQPLTQIAGMYNTMQSGIASAER MLBr_01113|M.leprae_Br4923 ALGGLQVATGHITLGNIQAFIQYVRQFNMPLSQVAGIYNTLQSGLASAER . * : : : .*: *. * :. . : *: :*.: MSMEG_6554|M.smegmatis_MC2_155 IQTTLDETELVIREQTGKR--------------DGEP-AVVFDNVTFGYR TH_2699|M.thermoresistible__bu IQTVLDEPELVVRDRTGQAG------TDHASGDQARPGTVELDRVSFEYR Mb1383|M.bovis_AF2122/97 LQVTLDETELAVREHP------------REPLDGEAPATVVFDHVTFGYR Rv1348|M.tuberculosis_H37Rv LQVTLDETELAVREHP------------REPLDGEAPATVVFDHVTFGYR MMAR_4037|M.marinum_M LQITLDEPVLEQHTG---------------LAEADSAAMVVFDKVSFGYR MUL_3902|M.ulcerans_Agy99 LQITLDEPVLEQHTG---------------LAEADSAAMVVFDKVSFGYR MAV_1566|M.avium_104 LQNTLDEHELEVREP--------------GEPTGESAQAVVFDNVGFGYR MAB_2262c|M.abscessus_ATCC_199 IAVALDETELDVIEAP---------------VTADAVASVSFEGVTFGYR Mflv_2250|M.gilvum_PYR-GCK VFDLLDAEEEPADP--------VEALPASAD---RRDGRVEFDGVWFSYR Mvan_4441|M.vanbaalenii_PYR-1 VFDLLDAEEEPSEPDRRLAPDSPTVLPARDG---RPGGRVEFDRVWFGYE MLBr_01113|M.leprae_Br4923 VFDLLDEPEELPDP--------MLALPPPHGQVPRINGRVEFQQVSFAYR : ** * :: * * *. MSMEG_6554|M.smegmatis_MC2_155 PDIPVLHDISLQLTPGTVTALVGPSGSGKSTLAALLARFHDVDAGAIRLG TH_2699|M.thermoresistible__bu PGVPVIRDVTLTLRPGTVTALVGPSGSGKSTLAALVARFHDVTQGAIRVD Mb1383|M.bovis_AF2122/97 PGVPVIQDVSLTLRPGTVTALVGPSGSGKSTLATLLARFHDVERGAIRVG Rv1348|M.tuberculosis_H37Rv PGVPVIQDVSLTLRPGTVTALVGPSGSGKSTLATLLARFHDVERGAIRVG MMAR_4037|M.marinum_M PGVPVIRDVSLQLRPGTVTALVGPSGSGKSTLAALLARFHDVEQGSIRVG MUL_3902|M.ulcerans_Agy99 PGVPVIRDVSLQLRPGTVTALVGPSGSGKSTLAALLARFHDVEQGSIRAG MAV_1566|M.avium_104 PDVPVIHDVSLTLRPGTLTALVGPSGSGKSTLAALLARFHDVDRGSITVG MAB_2262c|M.abscessus_ATCC_199 PGVPVIHDVSLTLRHGTVTALVGPSGSGKSTLASLLARFHDVERGAIRID Mflv_2250|M.gilvum_PYR-GCK PGTPVVEDLSLVAEPGQTIAIVGPTGAGKTTLVNLLMRFYDVDSGRILLD Mvan_4441|M.vanbaalenii_PYR-1 HGAPVIEDLSLVAEPGTTVAIVGPTGAGKTTLVNLLMRFYDVDSGRILLD MLBr_01113|M.leprae_Br4923 TGTPVIDDLSMVVEPGSTVAIVGPTGAGKTTLVNLLMRFYDVDSGQILID . **: *::: * *:***:*:**:**. *: **:** * * . MSMEG_6554|M.smegmatis_MC2_155 GRDIRTLTADELYRQVGFVLQDTQLVGGTVAENIALADPDASIERIQDAA TH_2699|M.thermoresistible__bu GRDIRTLTADELYRRVGFVLQDAQLVHGSVAENIALAEPDAGLERIRTAA Mb1383|M.bovis_AF2122/97 GQDIRSLAADELYTRVGFVLQEAQLVHGTAAENIALAVPDAPAEQVQVAA Rv1348|M.tuberculosis_H37Rv GQDIRSLAADELYTRVGFVLQEAQLVHGTAAENIALAVPDAPAEQVQVAA MMAR_4037|M.marinum_M GQDIRSLSADELYERVGLVLQETQLVHGTVAENIALAVPDAPAAQIQAAA MUL_3902|M.ulcerans_Agy99 GQDIRSLSADELYERVGLVLQETQLVHGTVAENIALAVPDAPAAQIQAAA MAV_1566|M.avium_104 GRDIRSMTADELYARVGFVLQETQLVHGTVAENIALAVPDATAAQIEQAA MAB_2262c|M.abscessus_ATCC_199 GTDIRTLTPDELYAKVGFVFQDVQLVAGTVRENIALACPEATDDDVESAA Mflv_2250|M.gilvum_PYR-GCK GTDITTVSRGSLRSRIGMVLQDTWLFAGTIYDNIAYGRPDAAHDEVIEAA Mvan_4441|M.vanbaalenii_PYR-1 GVDISAVSRASLRSRIGMVLQDTWLFAGTVYENIAYGRPEAGRDEVIDAA MLBr_01113|M.leprae_Br4923 GVDITTVSRHALRSRIGMVLQDAWLFDGTIAENIAYGRPQASEDEVMEAA * ** ::: * ::*:*:*:. *. *: :*** . *:* : ** MSMEG_6554|M.smegmatis_MC2_155 RDAQIHDRIMRLPNGYDTPLG-AASSLSGGEKQRLTIARAILADTPVLIL TH_2699|M.thermoresistible__bu RDAQIHDRITRMPDGYDSVLG-AGSALSGGERQRVTIARAILADTPVLVL Mb1383|M.bovis_AF2122/97 REAQIHDRVLRLPDGYDTVLG-ANSGLSGGERQRLTIARAILGDTPVLIL Rv1348|M.tuberculosis_H37Rv REAQIHDRVLRLPDGYDTVLG-ANSGLSGGERQRLTIARAILGDTPVLIL MMAR_4037|M.marinum_M GQAQIHDRVLRLRDGYDTVLG-AGAALSGGERQRLTIARAILADTPVLIL MUL_3902|M.ulcerans_Agy99 GQAQIHDRVLRLRDGYDTVLG-AGAALSGGERQRLTIARAILADTPVLIL MAV_1566|M.avium_104 REAQIHDRIMRLPHGYDTVLG-AGVGLSGGERQRLTIARAILADTEILIL MAB_2262c|M.abscessus_ATCC_199 RDAQIHERILRLPNGYDTVLD-TDTQLSGGEKQRLTIARALLADTPILIL Mflv_2250|M.gilvum_PYR-GCK TAAYVDRFVHTLPDGYDTRINDGGTNISAGEKQLITIARAILARPQVLVL Mvan_4441|M.vanbaalenii_PYR-1 KAAYVDRFVHTLPDGYETRIDDGGTNISAGEKQLITIARAVLAQPQLLIL MLBr_01113|M.leprae_Br4923 KAAYVDRFVHTLSAGYQTRVSGDGDNISAGEKQLITIARAFLARPQLLIL * :. : : **:: :. :*.**:* :*****.*. . :*:* MSMEG_6554|M.smegmatis_MC2_155 DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITHADQIVVLEGG TH_2699|M.thermoresistible__bu DEATAFADPESEYLVQQAINRLTRDRTVLVIAHRLHTITHADQIVVLDDG Mb1383|M.bovis_AF2122/97 DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITRADQIVVLDHG Rv1348|M.tuberculosis_H37Rv DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITRADQIVVLDHG MMAR_4037|M.marinum_M DEATAYADPESEYLVQQALNRLTKDRTVLVIAHRLHTITGADQIVVLDRG MUL_3902|M.ulcerans_Agy99 DEATAYADPESEYLVQQALNRLIKDRTVLVIAHRLHTITGADQIVVLDRG MAV_1566|M.avium_104 DEATAFADPESEYLVQQALNRLTRDRTVLVIAHRLHTITRADQIVVLDHG MAB_2262c|M.abscessus_ATCC_199 DEATAFADPESEYLVQQALGRLIDNRTVLVIAHRLHTIADADQIVVLDHG Mflv_2250|M.gilvum_PYR-GCK DEATSSVDTRTEVLIQHAMRELRRDRTSFIIAHRLSTIRDADTILVMEAG Mvan_4441|M.vanbaalenii_PYR-1 DEATSSVDTRTEVLIQHAMGRLRRERTSFIIAHRLSTIRDADLILVMQAG MLBr_01113|M.leprae_Br4923 DEATSSIDTRTEALIARATHDLLQDRTSFIIAHHLPTIRDADHILVVAAG ****: *..:* *: :* * :** ::***:* ** ** *:*: * MSMEG_6554|M.smegmatis_MC2_155 RIVETGTHERLLDAAGRYRQLWETGQRPALATAAGPTGEAVR--- TH_2699|M.thermoresistible__bu RIVEVGTHDELLAAGGRYRGLWDSGRYSSPDAGRPVSADAVEVGR Mb1383|M.bovis_AF2122/97 RIVERGTHEELLAAGGRYCRLWDTGQGSRVAVAAAQDGTR----- Rv1348|M.tuberculosis_H37Rv RIVERGTHEELLAAGGRYCRLWDTGQGSRVAVAAAQDGTR----- MMAR_4037|M.marinum_M QIAERGTHDELLAADGRYRRLWETGCGNQVELAAIQEGAR----- MUL_3902|M.ulcerans_Agy99 QIAERGTHDELLAADGRYRRLWETGCGNQVELAAIQEGAR----- MAV_1566|M.avium_104 RIVERGRHEELLAADGRYRRLWEGGRRGAVTVGTAGEVAR----- MAB_2262c|M.abscessus_ATCC_199 RVAETGTHTDLLANNGRYRRLWEGHRHEQSSVLAGGNL------- Mflv_2250|M.gilvum_PYR-GCK RIVERGTHSELLARRGEYWTMVNR--------------------- Mvan_4441|M.vanbaalenii_PYR-1 RIVERGTHEELLARGGEYAAMVNR--------------------- MLBr_01113|M.leprae_Br4923 KIVEQGSHAKLLARRGAYYRMTQA--------------------- ::.* * * ** * * : :