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MGFFKPRFPDVDPDTFLRKPLMERGRILAQSWVEYGFPSPRMVHAIYILKLIFGYALGVVIVATLTSGLP AFWHVAAWWNQPIVYQKVILWTVLLESIGVAGSWGPLAGKIKPMTGGIRFWTRPGTIRLRPWKWVPFTKG DRRTLLDVALYVALLVSVAVALFSPGVPSDSLSAALPGNTSGLVSPALLIAPMVLLVLVGLRDKTIFLGA RGEQYLPAMFFFAVLGFANFADMIIALKLLIVVVWVGAGASKFGKHFANVIPPMVSNSPAIAFRWLKRAH YRNFPRDLRPSRLAEVMAHAAGTTVEVLAPLTLLFSTNKWLTLAAAALMVSFHLFIISTFPLAVPLEWNV LFAYATIFLFLGFPAWQGYGVTSMSSPWLLAAIVAALLFFPILGNFRPDKVSFLPSMRQYAGNWASAVWA FAPGTEHKLNKVTRSSKNQLDQFIDFGYEPQWAEITMQRSIAWRSMHSQGRGLFSVLLKNLPDIDTRTVR EGEFICNSLIGFNFGDGHLHNEDLIAAMQTQAAFEPGELVVVWVESQAWGSKVQHYKVIDAALGVLERGT WKVADAVAEQPWLPNGPIPTQVTWSLRGRRERIRDGQEREHGALA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3453 | - | - | 100% (605) | hypothetical protein MUL_3453 |
| M. ulcerans Agy99 | MUL_0139 | - | e-119 | 40.00% (590) | hypothetical protein MUL_0139 |
| M. ulcerans Agy99 | MUL_3809 | - | e-113 | 39.08% (586) | hypothetical protein MUL_3809 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1466 | - | 1e-124 | 41.96% (591) | hypothetical protein Mb1466 |
| M. gilvum PYR-GCK | Mflv_2113 | - | 1e-119 | 40.60% (596) | hypothetical protein Mflv_2113 |
| M. tuberculosis H37Rv | Rv1431 | - | 1e-123 | 41.79% (591) | hypothetical protein Rv1431 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4552 | - | 1e-114 | 40.96% (586) | hypothetical protein MAB_4552 |
| M. marinum M | MMAR_1581 | - | 0.0 | 99.01% (605) | hypothetical protein MMAR_1581 |
| M. avium 104 | MAV_3343 | - | 1e-134 | 44.62% (585) | hypothetical protein MAV_3343 |
| M. smegmatis MC2 155 | MSMEG_5202 | - | 1e-120 | 40.50% (595) | hypothetical protein MSMEG_5202 |
| M. thermoresistible (build 8) | TH_4039 | - | 0.0 | 69.23% (598) | PUTATIVE conserved hypothetical membrane protein |
| M. vanbaalenii PYR-1 | Mvan_4591 | - | 1e-121 | 42.06% (592) | hypothetical protein Mvan_4591 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2113|M.gilvum_PYR-GCK MGFLKQDAPVVDYAEWSKGTRAERIVPMARHWAEVGFGTPVVIHLFYVVK
Mvan_4591|M.vanbaalenii_PYR-1 MGFLKQDAPVVDYAEWSKGTRAERIVPMARHWAEVGFGTPVVLHLFYVVK
MSMEG_5202|M.smegmatis_MC2_155 MGFLKQTAPQVDFEEWSKGTRAEKIRPMARHWAEVGFGTPVALHLFYVVK
MAB_4552|M.abscessus_ATCC_1997 MGFLKPTLPVVDVADWGKGTRAEKIRPMARHWAEVGFGTPVALHLFYVLK
Mb1466|M.bovis_AF2122/97 MGFLKPDLPDVDHDTWLTQPRRTRLQVVTRDWVEHGFGTPYAVYLLYLTK
Rv1431|M.tuberculosis_H37Rv MGFLKPDLPDVDHDTWLTQPRRTRLQVVTRDWVEHGFGTPYAVYLLYLTK
MAV_3343|M.avium_104 MGFMTPEFPDVDPQTWTGLPRSTRRQIMTRHWVEHGFGSPYAVYLFYVFK
MUL_3453|M.ulcerans_Agy99 MGFFKPRFPDVDPDTFLRKPLMERGRILAQSWVEYGFPSPRMVHAIYILK
MMAR_1581|M.marinum_M MGFFKPRFPDVDPDTFLRKPLMERGRILAQSWVEYGFPSPRMVHAIYILK
TH_4039|M.thermoresistible__bu MSFTQHDYPDVEPKEFLRRPLLERIRILSTHWVEHGFGTPFMVPLVYVAK
*.* * *: : . : :: *.* ** :* : .*: *
Mflv_2113|M.gilvum_PYR-GCK ILLYVLVAWLIVLS-TSGIDGFTDVAAWYHEPIVYQKVVFYTMLFEVVGL
Mvan_4591|M.vanbaalenii_PYR-1 ILLYILVAWLIVLT-TSGIDGFTNVAAWYHEPIVYQKVVFYTMLFEVVGL
MSMEG_5202|M.smegmatis_MC2_155 ICLYVLGAWLVVLS-TRGIDGFTAVADWWTEPIVFEKVVLYTMLYEVVGL
MAB_4552|M.abscessus_ATCC_1997 IALYILGGWLFAMVTTEGIDRWTDFS----LPIVFQKVVLYTMLFEVVGL
Mb1466|M.bovis_AF2122/97 IAVYVAAGAAIISL-TPGLGGLSRIGDWWTQPIVYQKVIVFTLLFEVLGF
Rv1431|M.tuberculosis_H37Rv IAVYVAAGAAIISL-NPGLGGLSRIGDWWTQPIVYQKVIVFTLLFEVLGF
MAV_3343|M.avium_104 IAGYVAGAAAVISL-TPGLGGLGRIADWWTQPIVYQKLVVFTLLFEILGL
MUL_3453|M.ulcerans_Agy99 LIFGYALGVVIVATLTSGLPAFWHVAAWWNQPIVYQKVILWTVLLESIGV
MMAR_1581|M.marinum_M LIFGYALGGVIVATLTSGLPAFWHVAAWWNQPIVYQKVILWTVLLESIGV
TH_4039|M.thermoresistible__bu VTLLYILGGVVIATVTSGLPAFWHVSQWWDQPIVYQKFILWTVLLEAIGL
: . . . *: .. ***::*.:.:*:* * :*.
Mflv_2113|M.gilvum_PYR-GCK GCGFGPLNNRFFPPMGSVLYWLRPRTIRLPPWPNRVPLTAGDTRTPVDVV
Mvan_4591|M.vanbaalenii_PYR-1 GCGFGPLNNRFFPPMGSILYWLRPRTIRLPPWPNRVPLTAGDSRTPFDVL
MSMEG_5202|M.smegmatis_MC2_155 GCGFGPLNNRFFPPMGSILYWLRPKTIRLPPWPDRVPLTKGDTRTVFDAV
MAB_4552|M.abscessus_ATCC_1997 GCGFGPLNNRFFPPLGSILYWLRPNTIRLPPWP-RIPLTKGSARTAVDIA
Mb1466|M.bovis_AF2122/97 GCGSGPLTGRFWPPIGGFLYWLRPNTIRLPAWPDKVPFTQGDTRTVVDVA
Rv1431|M.tuberculosis_H37Rv GCGSGPLTGRFWPPIGGFLYWLRPNTIRLPAWPDKVPFTQGDTRTVVDVA
MAV_3343|M.avium_104 GCGSGPLTARFWPPFGGFLYWLRPNTIRLPPWPDKVPFTAGDSRTVVDVA
MUL_3453|M.ulcerans_Agy99 AGSWGPLAGKIKPMTGGIRFWTRPGTIRLRPWK-WVPFTKGDRRTLLDVA
MMAR_1581|M.marinum_M AGSWGPLAGKIKPMTGGIRFWARPGTIRLRPWK-WVPFTKGDRRTLLDVA
TH_4039|M.thermoresistible__bu GGSWGPLAGKVKPMTGGIQFWLRRGTIRLRPWA-WVPLTAGNRRGWPDVI
. . *** :. * *.. :* * **** .* :*:* *. * *
Mflv_2113|M.gilvum_PYR-GCK LYAALLAVLVIALFSDGTG----PIPEIGSEVGVLPVWQTATIIGLLVVA
Mvan_4591|M.vanbaalenii_PYR-1 LYAALLVMLLFALFSDGTG----PIPELGSEVGVLPVWQTATIIGLLVVA
MSMEG_5202|M.smegmatis_MC2_155 LYGALLVVLLIAIFSDGTG----PLPALGTEIGVLPMWQIAAVLVLLAVL
MAB_4552|M.abscessus_ATCC_1997 LYAAFLGMVLVALLSQPT------------AAGLLPTWQTAAILGLLVIT
Mb1466|M.bovis_AF2122/97 LYAIVLIGGVWALLSPGSPGPGGTPVTAAGDVGLINPVLVVPTIVALGVL
Rv1431|M.tuberculosis_H37Rv LYAIVLIGGVWALLSPGSPGPGGTPVTAAGDVGLINPVLVVPTIVALGVL
MAV_3343|M.avium_104 LYLVVLGSGVAALLSPGR----GGPVTAAGDVGLIDPVLVVPAIVALALL
MUL_3453|M.ulcerans_Agy99 LYVALLVSVAVALFSPGVPSDSLSAALPGNTSGLVSPALLIAPMVLLVLV
MMAR_1581|M.marinum_M LYVALLVSVAVALFSPGVPSDSLSAALPGNTSGLVSPALLIAPMVLLVLV
TH_4039|M.thermoresistible__bu LYASLLISLVVALLSPGVTTASLLERLPDNTSGLVNPLLMVAPIVLLILV
** .* *::* *:: . : * :
Mflv_2113|M.gilvum_PYR-GCK GLRDKVIFLAARGEVYG--SLAVCFLFS--GADIIIAAKLVCLTIWIGAA
Mvan_4591|M.vanbaalenii_PYR-1 GLRDKVIFLAARGEVYG--SLAVCFLFS--GADIIIAAKLVCLVIWLGAA
MSMEG_5202|M.smegmatis_MC2_155 GLRDKVIFLAARGEVYA--SFTVAFLFAGHGVDAILAAKLVCMVIWLGAA
MAB_4552|M.abscessus_ATCC_1997 GLRDKVIFLAARGEVYG--ALTVAFLFT--GADMIMAAKLIFMVIWIGAA
Mb1466|M.bovis_AF2122/97 GLRDKTIFLAARGEHYW--LKLFVFFFP--FTDQIAAFKIIMLCLWWGAA
Rv1431|M.tuberculosis_H37Rv GLRDKTIFLAARGEHYW--LKLFVFFFP--FTDQIAAFKIIMLCLWWGAA
MAV_3343|M.avium_104 GLRDKTIFLAARGEHYG--LTLLVFFFG--FTDQIAAFKIIMLALWWGAA
MUL_3453|M.ulcerans_Agy99 GLRDKTIFLGARGEQYLPAMFFFAVLGFANFADMIIALKLLIVVVWVGAG
MMAR_1581|M.marinum_M GLRDKTIFLGARGEQYLPAMFFFAVLGFANFADMIIALKLLIVVVWVGAG
TH_4039|M.thermoresistible__bu GLRDKTIFLAARGEQYLPAMVFFAVLGFT---DMIVALKLLIVVVWVCAG
*****.***.**** * . .: * * * *:: : :* *.
Mflv_2113|M.gilvum_PYR-GCK TSKLNKHFPFVISTMMSNNPVIRPR---SIKRKFFEHFPDDLRPGRASRV
Mvan_4591|M.vanbaalenii_PYR-1 TSKLNKHFPFVISTMMSNNPVMRPR---WIKRKFFEHFPDDLRPGRASRF
MSMEG_5202|M.smegmatis_MC2_155 TSKLNKHFPFVISTMMSNNPVLRPR---FIKRKFFEHFPDDLRPGRPSRW
MAB_4552|M.abscessus_ATCC_1997 TSKLNRHFPFVISTMMSNNPLIRAR---RLKRAFFEKFPDDLRPGRLSRV
Mb1466|M.bovis_AF2122/97 TSKLNHHFPYVVAVMTSNNALLRSRVFNPIKHLLYRDHANDLRPSWLPKL
Rv1431|M.tuberculosis_H37Rv TSKLNHHFPYVVAVMTSNNALLRSRVFNPIKHLLYRDHANDLRPSWLPKL
MAV_3343|M.avium_104 TSKLNHHFPYVVAVMMSNSPLLRARAFNWFKRRLYLDPVDDLRPSWIPKV
MUL_3453|M.ulcerans_Agy99 ASKFGKHFANVIPPMVSNSPAIAFR---WLKRAHYRNFPRDLRPSRLAEV
MMAR_1581|M.marinum_M ASKFGKHFANVIPPMVSNSPAIAFR---WLKRAHYRNFPRDLRPSRLAEV
TH_4039|M.thermoresistible__bu VSKFGRHFARVIPPMTSNSPTVATLP--AFKRAMYRDPRNDLRPSRLAEF
.**:.:**. *:. * **.. : :*: : . ****. ..
Mflv_2113|M.gilvum_PYR-GCK LAHFS-TAIEMLVPLVLFFSHGG--WPTAIAAFVMLVFHFGILSAIPMGV
Mvan_4591|M.vanbaalenii_PYR-1 LAHFS-TAIEGLVPLVLFFSHGG--WATAIAAFVMLVFHFGILSAIPMGV
MSMEG_5202|M.smegmatis_MC2_155 LAHVS-TAIEMLVPLALFFSHGG--WPTALAATVMICFHFGILSAIPMGV
MAB_4552|M.abscessus_ATCC_1997 VAHVS-TAVEGLVPFALFFSHGG--WVTTVAAGVMVCFHLGILTAIPMGV
Mb1466|M.bovis_AF2122/97 MAHGGGTTAEFLVPGILVLVADGHPWRWFLIG-FMVLFHLNILSNLPMGV
Rv1431|M.tuberculosis_H37Rv MAHGGGTTAEFLVPGILVLVADGHPWRWFLIG-FMVLFHLNILSNLPMGV
MAV_3343|M.avium_104 MAHVGGTTAEFLVPLVLVFVADGHRWAWFLIA-FMVLFHLNIASTIPMGV
MUL_3453|M.ulcerans_Agy99 MAHAAGTTVEVLAPLTLLFSTNK--WLTLAAAALMVSFHLFIISTFPLAV
MMAR_1581|M.marinum_M MAHAAGTTVEILAPLTLLFSTNK--WLTLAAAALMVSFHLFIISTFPLAV
TH_4039|M.thermoresistible__bu MAHVLGTVVEVVAPLVLLFSHNK--TLTVAAVVLMLGLHLYIISAFPLAV
:** *. * :.* *.: . .*: :*: * : :*:.*
Mflv_2113|M.gilvum_PYR-GCK PLEWNVFMMFSVLALFVGN---AGIGLGDLQSPWP-IVLFAVVAGTVVIG
Mvan_4591|M.vanbaalenii_PYR-1 PLEWNVFMMFSVLALFVGN---AGIGLADLQSPWP-ILLFAAVAGTVVIG
MSMEG_5202|M.smegmatis_MC2_155 PLEWNVFMIFCVATLFVGH---ADVGITDLSTPLP-LLLLAVLVTTVTLG
MAB_4552|M.abscessus_ATCC_1997 PLEWNVFMIFGVLALFVSH---ANVGLSDMQHPAPVLLLLAVSAGVVATG
Mb1466|M.bovis_AF2122/97 PLEWNVFFIFSLCYLFGHY---GAITATDLRSPLLLAIVIAVVAVV-IMG
Rv1431|M.tuberculosis_H37Rv PLEWNVFFIFSLCYLFGHY---GAITATDLRSPLLLAIVIAVVAVV-IMG
MAV_3343|M.avium_104 PLEWNVFFIFSLFYLFGHY---AGVTATGLSSPLLLVILIAALAVVPILG
MUL_3453|M.ulcerans_Agy99 PLEWNVLFAYATIFLFLGFPAWQGYGVTSMSSPWLLAAIVAALLFFPILG
MMAR_1581|M.marinum_M PLEWNVLFAYATIFLFLGFPAWQGYGVTSMSSPWLLAAIVAALLFFPILG
TH_4039|M.thermoresistible__bu PLEWNVLFSFATVFLFLGFPSWEGYAVGDMSSPWLTVVIVAALLFFPILG
******:: : ** .: * :.*. *
Mflv_2113|M.gilvum_PYR-GCK NLFPRKVSFLPGMRYYAGNWDTTLWCVKPSASEKITSGIVAIASMPAAQM
Mvan_4591|M.vanbaalenii_PYR-1 NLFPRKVSFLPGMRYYAGNWDTTLWCVKPSAAEKIANGIVAIASMPAAQM
MSMEG_5202|M.smegmatis_MC2_155 NLFPRKISFLPGMRYYAGNWDTSLWCVKPSAAEKIEKNIVAIASMPAAQM
MAB_4552|M.abscessus_ATCC_1997 NLLPRKVSFLPGMRYYAGNWDTTLWCIKPSASAKIEKGIVAIASMPQAQM
Mb1466|M.bovis_AF2122/97 NLLPEKISFLPAMRYYAGNWATSIWCFRGDAEATMETSVVKSSALVVNQL
Rv1431|M.tuberculosis_H37Rv NLLPEKISFLPAMRYYAGNWATSIWCFRGDAEATMETSVVKSSALVVNQL
MAV_3343|M.avium_104 NLFPQQISFLPAMRYYAGNWATSTWCFRRGAEDKIEANITKASALVPNQL
MUL_3453|M.ulcerans_Agy99 NFRPDKVSFLPSMRQYAGNWASAVWAFAPGTEHKLNK-VTRSSKNQLDQF
MMAR_1581|M.marinum_M NFRPDKVSFLPSMRQYAGNWASAVWAFAPGTEHKLNK-VTRSSKNQLDQF
TH_4039|M.thermoresistible__bu NVRPDKVSFLPSMRQYSGNWACSVWAFAPGAEAKLDR-VKRPAINQIDQF
*. * ::****.** *:*** : *.. .: .: : : *:
Mflv_2113|M.gilvum_PYR-GCK EKFYGSKETAEMYQYMGYAFRSFNTHGRAMFTLAHRAMAGQ-DEGEYVLT
Mvan_4591|M.vanbaalenii_PYR-1 EKFYGSKETAEVYQYMGYAFRSFNTHGRAMFTLAHRAMADG-SEDDYVLT
MSMEG_5202|M.smegmatis_MC2_155 ERYYGSPETAQMYLYMGYAFRGFNSHGRALFTLAHRAMAGH-DEGEYVLT
MAB_4552|M.abscessus_ATCC_1997 ERYYGSKDAAQIYMYIGYAFRAMNTHGRAMFTLAHRAMAGQ-DESEYVIT
Mb1466|M.bovis_AF2122/97 AKLYDG-ATAEIMTDQVAAFRAMHTHGRALNGLLPRALD---DEAHYRIR
Rv1431|M.tuberculosis_H37Rv AKLYDG-ATAEIMTDKVAAFRAMHTHGRALNGLLPRALD---DEAHYRIR
MAV_3343|M.avium_104 ARLYDP-QSAELMIDKLMGWRSMHTHGRALGGLVPRALPGGADEADYLLR
MUL_3453|M.ulcerans_Agy99 IDFGYEPQWAEITMQRSIAWRSMHSQGRGLFSVLLKNLP---DIDTRTVR
MMAR_1581|M.marinum_M IDFGYEPQWAEITMQHSIAWRSMHSQGRGLFSVLLKNLP---DIDTRTVR
TH_4039|M.thermoresistible__bu IAYGYEPEWAAVIMNLPATFRAMHTQGRGLLSVLVKNLP---DIDTRTVR
* : :*.::::**.: : : : . :
Mflv_2113|M.gilvum_PYR-GCK DGERICSTAIGWNFGDGHMHNEQLITALQKRCRFEPGEVRVLILDAQPIH
Mvan_4591|M.vanbaalenii_PYR-1 DGERICSTAIGWNFGDGHMHNEQLIAALQKRCQFEPGEVRVLLLDAQPIH
MSMEG_5202|M.smegmatis_MC2_155 DGERIVSTAIGWNFGDGHMSNEQLVDALQKRCHFEPGEVRIVMLDAQPIQ
MAB_4552|M.abscessus_ATCC_1997 DGERICSTAIGWNFGDGHMHNEQLIAAMQERCHFEPGEVRIVLLDAQPIH
Mb1466|M.bovis_AF2122/97 EGEIVAGPLVGWNFGEGHLHNEQLVAAVQRRCNFADGDLRVIILEGQPIH
Rv1431|M.tuberculosis_H37Rv EGEIVAGPLVGWNFGEGHLHNEQLVAAVQRRCNFADGDLRVIILEGQPIH
MAV_3343|M.avium_104 DGEIVAGPLIGWNFGEGHLHNEQLLAAVQRRCNFDEGEVRVIILEAQPIQ
MUL_3453|M.ulcerans_Agy99 EGEFICNSLIGFNFGDGHLHNEDLIAAMQTQAAFEPGELVVVWVESQAWG
MMAR_1581|M.marinum_M EGEFICNSLIGFNFGDGHLHNEDLIAAMQTQAAFEPGELVVVWVESQAWG
TH_4039|M.thermoresistible__bu EGEWVCNSLIGWNFGDGHLHDERMIAAVQEQVGFEPGDLVVAWAESQAWG
:** : .. :*:***:**: :* :: *:* : * *:: : :.*.
Mflv_2113|M.gilvum_PYR-GCK KQRQEYRLVDAATGEFERGYVMVADMVTRQPWD---DTVPVHVTWQKSG-
Mvan_4591|M.vanbaalenii_PYR-1 RQRQEYRLVDAATGEFERGYVMVADMVTRQPWD---DTVPVHVTWRR---
MSMEG_5202|M.smegmatis_MC2_155 RQTQNYRLVDAATGEFERGYVKVADMVTRQPWD---DDVPVHGVHSLSGE
MAB_4552|M.abscessus_ATCC_1997 RQTQRYRLVDAATGEFESGYVRVADMVNRQPWD---DELPVQVNS-----
Mb1466|M.bovis_AF2122/97 VQKQWYRIVDAKTGLFEAGYVTVEDMLSRQPWPEPGDEFPVHVTTQRGTP
Rv1431|M.tuberculosis_H37Rv VQKQWYRIVDAKTGLFEAGYVTVEDMLSRQPWPEPGDEFPVHVTTQRGTP
MAV_3343|M.avium_104 RQTQAYRIVDAKTGLIEAGHVDVASMLSRQPWPEPGDEYPVHVHG-----
MUL_3453|M.ulcerans_Agy99 SKVQHYKVIDAALGVLERGTWKVADAVAEQPWLP-NGPIPTQVTWSLRGR
MMAR_1581|M.marinum_M SKVQHYKVIDAALGVLERGTWKVADAVAEQPWLP-NGPIPTQVTWSLGGR
TH_4039|M.thermoresistible__bu SPVQHYKLIDAALGVIETGTWRVDDVAEAQPWLP-NGPVPTTVTWS----
* *:::** * :* * * . *** . *.
Mflv_2113|M.gilvum_PYR-GCK ----------------
Mvan_4591|M.vanbaalenii_PYR-1 ----------------
MSMEG_5202|M.smegmatis_MC2_155 RREHA-----------
MAB_4552|M.abscessus_ATCC_1997 ----------------
Mb1466|M.bovis_AF2122/97 SKP-------------
Rv1431|M.tuberculosis_H37Rv SKP-------------
MAV_3343|M.avium_104 ----------------
MUL_3453|M.ulcerans_Agy99 RERIRDGQEREHGALA
MMAR_1581|M.marinum_M RERIRDGQDREHGALA
TH_4039|M.thermoresistible__bu --RFRDGR----GAVV