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MGFLKPDLPDVDHDTWLTQPRRTRLQVVTRDWVEHGFGTPYAVYLLYLTKIAVYVAAGAAIISLTPGLGG LSRIGDWWTQPIVYQKVIVFTLLFEVLGFGCGSGPLTGRFWPPIGGFLYWLRPNTIRLPAWPDKVPFTQG DTRTVVDVALYAIVLIGGVWALLSPGSPGPGGTPVTAAGDVGLINPVLVVPTIVALGVLGLRDKTIFLAA RGEHYWLKLFVFFFPFTDQIAAFKIIMLCLWWGAATSKLNHHFPYVVAVMTSNNALLRSRVFNPIKHLLY RDHANDLRPSWLPKLMAHGGGTTAEFLVPGILVLVADGHPWRWFLIGFMVLFHLNILSNLPMGVPLEWNV FFIFSLCYLFGHYGAITATDLRSPLLLAIVIAVVAVVIMGNLLPEKISFLPAMRYYAGNWATSIWCFRGD AEATMETSVVKSSALVVNQLAKLYDGATAEIMTDQVAAFRAMHTHGRALNGLLPRALDDEAHYRIREGEI VAGPLVGWNFGEGHLHNEQLVAAVQRRCNFADGDLRVIILEGQPIHVQKQWYRIVDAKTGLFEAGYVTVE DMLSRQPWPEPGDEFPVHVTTQRGTPSKP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1466 | - | - | 100% (589) | hypothetical protein Mb1466 |
| M. bovis AF2122 / 97 | Mb1163 | - | e-151 | 48.12% (586) | hypothetical protein Mb1163 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2113 | - | 1e-150 | 47.62% (588) | hypothetical protein Mflv_2113 |
| M. tuberculosis H37Rv | Rv1431 | - | 0.0 | 99.66% (589) | hypothetical protein Rv1431 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4552 | - | 1e-142 | 47.36% (587) | hypothetical protein MAB_4552 |
| M. marinum M | MMAR_2236 | - | 0.0 | 85.93% (583) | hypothetical protein MMAR_2236 |
| M. avium 104 | MAV_3343 | - | 0.0 | 75.30% (583) | hypothetical protein MAV_3343 |
| M. smegmatis MC2 155 | MSMEG_5202 | - | 1e-147 | 46.06% (584) | hypothetical protein MSMEG_5202 |
| M. thermoresistible (build 8) | TH_0493 | - | 1e-154 | 48.47% (588) | conserved membrane protein |
| M. ulcerans Agy99 | MUL_0139 | - | 1e-153 | 48.55% (585) | hypothetical protein MUL_0139 |
| M. vanbaalenii PYR-1 | Mvan_4591 | - | 1e-149 | 47.11% (588) | hypothetical protein Mvan_4591 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2113|M.gilvum_PYR-GCK MGFLKQDAPVVDYAEWSKGTRAERIVPMARHWAEVGFGTPVVIHLFYVVK
Mvan_4591|M.vanbaalenii_PYR-1 MGFLKQDAPVVDYAEWSKGTRAERIVPMARHWAEVGFGTPVVLHLFYVVK
MSMEG_5202|M.smegmatis_MC2_155 MGFLKQTAPQVDFEEWSKGTRAEKIRPMARHWAEVGFGTPVALHLFYVVK
TH_0493|M.thermoresistible__bu MGFLKQNTPVVDYEQWRTGTRAEKIKPMARHWAEVGFGTPVALHLFYVLK
MAB_4552|M.abscessus_ATCC_1997 MGFLKPTLPVVDVADWGKGTRAEKIRPMARHWAEVGFGTPVALHLFYVLK
MUL_0139|M.ulcerans_Agy99 MGFLKPVLPQVDIVEWGKGTRSEKIRPMARHWAEVGFGTPVVMHLFYVGK
Mb1466|M.bovis_AF2122/97 MGFLKPDLPDVDHDTWLTQPRRTRLQVVTRDWVEHGFGTPYAVYLLYLTK
Rv1431|M.tuberculosis_H37Rv MGFLKPDLPDVDHDTWLTQPRRTRLQVVTRDWVEHGFGTPYAVYLLYLTK
MMAR_2236|M.marinum_M MGFMSPDLPDVDHETWHTLPRATRLQVVTRHWAEHGFGTPYAVYLLYLLK
MAV_3343|M.avium_104 MGFMTPEFPDVDPQTWTGLPRSTRRQIMTRHWVEHGFGSPYAVYLFYVFK
***:. * ** * .* : ::*.*.* ***:* .::*:*: *
Mflv_2113|M.gilvum_PYR-GCK ILLYVLVAWLIVLS-TSGIDGFTDVAAWYHEPIVYQKVVFYTMLFEVVGL
Mvan_4591|M.vanbaalenii_PYR-1 ILLYILVAWLIVLT-TSGIDGFTNVAAWYHEPIVYQKVVFYTMLFEVVGL
MSMEG_5202|M.smegmatis_MC2_155 ICLYVLGAWLVVLS-TRGIDGFTAVADWWTEPIVFEKVVLYTMLYEVVGL
TH_0493|M.thermoresistible__bu IGLYILGAWLIAAA-TPGIGGLTDVADWWSEPIVFQKVVLYTMLFEVVGL
MAB_4552|M.abscessus_ATCC_1997 IALYILGGWLFAMVTTEGIDRWTD----FSLPIVFQKVVLYTMLFEVVGL
MUL_0139|M.ulcerans_Agy99 ILLYILVGWLIVFS-TKGIEGFTDVKSWYTEPIVFQKVVLYTMLFEVVGL
Mb1466|M.bovis_AF2122/97 IAVYVAAGAAIISL-TPGLGGLSRIGDWWTQPIVYQKVIVFTLLFEVLGF
Rv1431|M.tuberculosis_H37Rv IAVYVAAGAAIISL-NPGLGGLSRIGDWWTQPIVYQKVIVFTLLFEVLGF
MMAR_2236|M.marinum_M IGIYVAAPAAIISL-TPGLGGLGHIADWWTQPIVYQKVIIFTLLFEVLGF
MAV_3343|M.avium_104 IAGYVAGAAAVISL-TPGLGGLGRIADWWTQPIVYQKLVVFTLLFEILGL
* *: . . *: : ***::*::.:*:*:*::*:
Mflv_2113|M.gilvum_PYR-GCK GCGFGPLNNRFFPPMGSVLYWLRPRTIRLPPWPNRVPLTAGDTRTPVDVV
Mvan_4591|M.vanbaalenii_PYR-1 GCGFGPLNNRFFPPMGSILYWLRPRTIRLPPWPNRVPLTAGDSRTPFDVL
MSMEG_5202|M.smegmatis_MC2_155 GCGFGPLNNRFFPPMGSILYWLRPKTIRLPPWPDRVPLTKGDTRTVFDAV
TH_0493|M.thermoresistible__bu GCGFGPLNNRFFPPMGSILYWLRPNTIRLPPWPNRIPFTRGTTRTPVDVA
MAB_4552|M.abscessus_ATCC_1997 GCGFGPLNNRFFPPLGSILYWLRPNTIRLPPWP-RIPLTKGSARTAVDIA
MUL_0139|M.ulcerans_Agy99 GCGFGPLNNRFFPPMGSSLYWLRFGTIRLPPWPERVPWTAGTKRKPVDVA
Mb1466|M.bovis_AF2122/97 GCGSGPLTGRFWPPIGGFLYWLRPNTIRLPAWPDKVPFTQGDTRTVVDVA
Rv1431|M.tuberculosis_H37Rv GCGSGPLTGRFWPPIGGFLYWLRPNTIRLPAWPDKVPFTQGDTRTVVDVA
MMAR_2236|M.marinum_M GCGSGPLTGRFMPPVGGFLYWLRPKTIRLPPWPAKVPFTDGDTRTVVDVT
MAV_3343|M.avium_104 GCGSGPLTARFWPPFGGFLYWLRPNTIRLPPWPDKVPFTAGDSRTVVDVA
*** ***. ** **.*. ***** *****.** ::* * * *. .*
Mflv_2113|M.gilvum_PYR-GCK LYAALLAVLVIALFSDGTGP----IPEIGSEVGVLPVWQTATIIGLLVVA
Mvan_4591|M.vanbaalenii_PYR-1 LYAALLVMLLFALFSDGTGP----IPELGSEVGVLPVWQTATIIGLLVVA
MSMEG_5202|M.smegmatis_MC2_155 LYGALLVVLLIAIFSDGTGP----LPALGTEIGVLPMWQIAAVLVLLAVL
TH_0493|M.thermoresistible__bu LYGALLVMLVVALASGGTGP----VEALGTDIGLLPAWQIWAVLGLLAAA
MAB_4552|M.abscessus_ATCC_1997 LYAAFLGMVLVALLSQP------------TAAGLLPTWQTAAILGLLVIT
MUL_0139|M.ulcerans_Agy99 LYALLLIMLVTALFTDGSGP----MPELGSKVGLLPMWEIVMILLLLAMV
Mb1466|M.bovis_AF2122/97 LYAIVLIGGVWALLSPGSPGPGGTPVTAAGDVGLINPVLVVPTIVALGVL
Rv1431|M.tuberculosis_H37Rv LYAIVLIGGVWALLSPGSPGPGGTPVTAAGDVGLINPVLVVPTIVALGVL
MMAR_2236|M.marinum_M LYAIVLISGGWALFSPGHAG----PVTASGDVGLIDPILVVPTIIALALL
MAV_3343|M.avium_104 LYLVVLGSGVAALLSPGRGG----PVTAAGDVGLIDPVLVVPAIVALALL
** .* *: : *:: : *
Mflv_2113|M.gilvum_PYR-GCK GLRDKVIFLAARGEVYGSLAVCFLFS--GADIIIAAKLVCLTIWIGAATS
Mvan_4591|M.vanbaalenii_PYR-1 GLRDKVIFLAARGEVYGSLAVCFLFS--GADIIIAAKLVCLVIWLGAATS
MSMEG_5202|M.smegmatis_MC2_155 GLRDKVIFLAARGEVYASFTVAFLFAGHGVDAILAAKLVCMVIWLGAATS
TH_0493|M.thermoresistible__bu GLRDKVIFLAARGEVYASLTVTFLFA--GPDMIVAAKIVFLIIWLGAGVS
MAB_4552|M.abscessus_ATCC_1997 GLRDKVIFLAARGEVYGALTVAFLFT--GADMIMAAKLIFMVIWIGAATS
MUL_0139|M.ulcerans_Agy99 GLRDKVIFLAARGEVYGTLTVTFLLG--GIDMIVAAKLVFLVIWMGAATS
Mb1466|M.bovis_AF2122/97 GLRDKTIFLAARGEHYWLKLFVFFFP--FTDQIAAFKIIMLCLWWGAATS
Rv1431|M.tuberculosis_H37Rv GLRDKTIFLAARGEHYWLKLFVFFFP--FTDQIAAFKIIMLCLWWGAATS
MMAR_2236|M.marinum_M GLRDKTVFLAARGEHYWLKLLVFFFP--FTDQIAAFKIIMLCLWWGAATS
MAV_3343|M.avium_104 GLRDKTIFLAARGEHYGLTLLVFFFG--FTDQIAAFKIIMLALWWGAATS
*****.:******* * . *:: * * * *:: : :* **..*
Mflv_2113|M.gilvum_PYR-GCK KLNKHFPFVISTMMSNNPVIRPR---SIKRKFFEHFPDDLRPGRASRVLA
Mvan_4591|M.vanbaalenii_PYR-1 KLNKHFPFVISTMMSNNPVMRPR---WIKRKFFEHFPDDLRPGRASRFLA
MSMEG_5202|M.smegmatis_MC2_155 KLNKHFPFVISTMMSNNPVLRPR---FIKRKFFEHFPDDLRPGRPSRWLA
TH_0493|M.thermoresistible__bu KLNRHFPFVISTMMSNNPVFRPR---WIKRRFFERFPDDLRPGRASRWLA
MAB_4552|M.abscessus_ATCC_1997 KLNRHFPFVISTMMSNNPLIRAR---RLKRAFFEKFPDDLRPGRLSRVVA
MUL_0139|M.ulcerans_Agy99 KLNRHFPFVISTMMSNNPLFRPR---FIKRMFFAKFPDDLRPGLLSRMLA
Mb1466|M.bovis_AF2122/97 KLNHHFPYVVAVMTSNNALLRSRVFNPIKHLLYRDHANDLRPSWLPKLMA
Rv1431|M.tuberculosis_H37Rv KLNHHFPYVVAVMTSNNALLRSRVFNPIKHLLYRDHANDLRPSWLPKLMA
MMAR_2236|M.marinum_M KLNHHFPYVVAVMTSNNALLRGRLFNPIKHLLYRDHVNDLRPSWLPKIMA
MAV_3343|M.avium_104 KLNHHFPYVVAVMMSNSPLLRARAFNWFKRRLYLDPVDDLRPSWIPKVMA
***:***:*::.* **..::* * :*: :: :****. .: :*
Mflv_2113|M.gilvum_PYR-GCK HFS-TAIEMLVPLVLFFSHGG--WPTAIAAFVMLVFHFGILSAIPMGVPL
Mvan_4591|M.vanbaalenii_PYR-1 HFS-TAIEGLVPLVLFFSHGG--WATAIAAFVMLVFHFGILSAIPMGVPL
MSMEG_5202|M.smegmatis_MC2_155 HVS-TAIEMLVPLALFFSHGG--WPTALAATVMICFHFGILSAIPMGVPL
TH_0493|M.thermoresistible__bu HLA-TAIELLVPLVLFFSHGG--WATAIAAGVMVLFHFGILSAIPMGVPL
MAB_4552|M.abscessus_ATCC_1997 HVS-TAVEGLVPFALFFSHGG--WVTTVAAGVMVCFHLGILTAIPMGVPL
MUL_0139|M.ulcerans_Agy99 HLS-TFIEMFVPVALFLSHGG--WPTTAAAIAMVCFHLGILTAIPMGVPL
Mb1466|M.bovis_AF2122/97 HGGGTTAEFLVPGILVLVADGHPWRWFLIG-FMVLFHLNILSNLPMGVPL
Rv1431|M.tuberculosis_H37Rv HGGGTTAEFLVPGILVLVADGHPWRWFLIG-FMVLFHLNILSNLPMGVPL
MMAR_2236|M.marinum_M HVGGTTAEFLVPAVLVLVAGDQPWRWFLIG-FMVIFHLNILSNLPMGVPL
MAV_3343|M.avium_104 HVGGTTAEFLVPLVLVFVADGHRWAWFLIA-FMVLFHLNIASTIPMGVPL
* . * * :** *.: .. * . *: **:.* : :******
Mflv_2113|M.gilvum_PYR-GCK EWNVFMMFSVLALFVGNAGIGLGDLQSPWPIVLFAVVAG-TVVIGNLFPR
Mvan_4591|M.vanbaalenii_PYR-1 EWNVFMMFSVLALFVGNAGIGLADLQSPWPILLFAAVAG-TVVIGNLFPR
MSMEG_5202|M.smegmatis_MC2_155 EWNVFMIFCVATLFVGHADVGITDLSTPLPLLLLAVLVT-TVTLGNLFPR
TH_0493|M.thermoresistible__bu EWNVFMIFGVLWLFVTHAQFGLADVGNPWPVAALSLVLAGTVVLGNLFPH
MAB_4552|M.abscessus_ATCC_1997 EWNVFMIFGVLALFVSHANVGLSDMQHPAPVLLLLAVSAGVVATGNLLPR
MUL_0139|M.ulcerans_Agy99 EWNVFMIFGVLALFVGHADLGLTDVKSPVPVAILFAVVAGIVILGNLFPR
Mb1466|M.bovis_AF2122/97 EWNVFFIFSLCYLFGHYGAITATDLRSPLLLAIVIAVVAVV-IMGNLLPE
Rv1431|M.tuberculosis_H37Rv EWNVFFIFSLCYLFGHYGAITATDLRSPLLLAIVIAVVAVV-IMGNLLPE
MMAR_2236|M.marinum_M EWNVFFIFSLFYLFGHYGSIRAIDLRSPLLLAIVLAAVAVV-VAGNLFPE
MAV_3343|M.avium_104 EWNVFFIFSLFYLFGHYAGVTATGLSSPLLLVILIAALAVVPILGNLFPQ
*****::* : ** . . .: * : . ***:*.
Mflv_2113|M.gilvum_PYR-GCK KVSFLPGMRYYAGNWDTTLWCVKPSASEKITSGIVAIASMPAAQMEKFYG
Mvan_4591|M.vanbaalenii_PYR-1 KVSFLPGMRYYAGNWDTTLWCVKPSAAEKIANGIVAIASMPAAQMEKFYG
MSMEG_5202|M.smegmatis_MC2_155 KISFLPGMRYYAGNWDTSLWCVKPSAAEKIEKNIVAIASMPAAQMERYYG
TH_0493|M.thermoresistible__bu KVSFLPGMRYYAGNWDTTLWCVKPSAEEKINNGIVAIASMPAAQMERYYG
MAB_4552|M.abscessus_ATCC_1997 KVSFLPGMRYYAGNWDTTLWCIKPSASAKIEKGIVAIASMPQAQMERYYG
MUL_0139|M.ulcerans_Agy99 KISFLPGMRYYAGNWDTTLWCIKPSADAKIKRGIVAIASMPQAQLERFYG
Mb1466|M.bovis_AF2122/97 KISFLPAMRYYAGNWATSIWCFRGDAEATMETSVVKSSALVVNQLAKLYD
Rv1431|M.tuberculosis_H37Rv KISFLPAMRYYAGNWATSIWCFRGDAEATMETSVVKSSALVVNQLAKLYD
MMAR_2236|M.marinum_M KISFLPAMRYYAGNWATSVWCFRAGAEEKIEASVVKSSALVVNQLAKLYD
MAV_3343|M.avium_104 QISFLPAMRYYAGNWATSTWCFRRGAEDKIEANITKASALVPNQLARLYD
::****.******** *: **.: .* .: .:. ::: *: : *.
Mflv_2113|M.gilvum_PYR-GCK SKETAEMYQYMGYAFRSFNTHGRAMFTLAHRAMAG-QDEGEYVLTDGERI
Mvan_4591|M.vanbaalenii_PYR-1 SKETAEVYQYMGYAFRSFNTHGRAMFTLAHRAMAD-GSEDDYVLTDGERI
MSMEG_5202|M.smegmatis_MC2_155 SPETAQMYLYMGYAFRGFNSHGRALFTLAHRAMAG-HDEGEYVLTDGERI
TH_0493|M.thermoresistible__bu SKETAEMYLYMGYAFRAFNTHGKALFTLAHRAMAG-HDEDDYTIIDGERI
MAB_4552|M.abscessus_ATCC_1997 SKDAAQIYMYIGYAFRAMNTHGRAMFTLAHRAMAG-QDESEYVITDGERI
MUL_0139|M.ulcerans_Agy99 -KDRAQIPMYLGYAFRAMNTHGRALFTLAHRAMAG-QDEDDYVITDGERI
Mb1466|M.bovis_AF2122/97 -GATAEIMTDQVAAFRAMHTHGRALNGLLPRALD---DEAHYRIREGEIV
Rv1431|M.tuberculosis_H37Rv -GATAEIMTDKVAAFRAMHTHGRALNGLLPRALD---DEAHYRIREGEIV
MMAR_2236|M.marinum_M -ANTAEIMADKTAAFRAMHTHGRALNGLLPRAIG---NEAEYKVREGEIV
MAV_3343|M.avium_104 -PQSAELMIDKLMGWRSMHTHGRALGGLVPRALPGGADEADYLLRDGEIV
*:: .:*.:::**:*: * **: .* .* : :** :
Mflv_2113|M.gilvum_PYR-GCK CSTAIGWNFGDGHMHNEQLITALQKRCRFEPGEVRVLILDAQPIHKQRQE
Mvan_4591|M.vanbaalenii_PYR-1 CSTAIGWNFGDGHMHNEQLIAALQKRCQFEPGEVRVLLLDAQPIHRQRQE
MSMEG_5202|M.smegmatis_MC2_155 VSTAIGWNFGDGHMSNEQLVDALQKRCHFEPGEVRIVMLDAQPIQRQTQN
TH_0493|M.thermoresistible__bu CSTAIGWNFGDGHMHNEQLIEAMQQRCGFEPGEVRVVLLDAQPIHRQTQQ
MAB_4552|M.abscessus_ATCC_1997 CSTAIGWNFGDGHMHNEQLIAAMQERCHFEPGEVRIVLLDAQPIHRQTQR
MUL_0139|M.ulcerans_Agy99 CSTAVGWNFGDGHMHNEQLIAAMQQRCNFEPGEVRIVLLDAQPIHKQTQA
Mb1466|M.bovis_AF2122/97 AGPLVGWNFGEGHLHNEQLVAAVQRRCNFADGDLRVIILEGQPIHVQKQW
Rv1431|M.tuberculosis_H37Rv AGPLVGWNFGEGHLHNEQLVAAVQRRCNFADGDLRVIILEGQPIHVQKQW
MMAR_2236|M.marinum_M AGPLVGWNFGEGHLHNEQLVQAVQRRCNFADGDLRVIILEGQPIHIQKQW
MAV_3343|M.avium_104 AGPLIGWNFGEGHLHNEQLLAAVQRRCNFDEGEVRVIILEAQPIQRQTQA
.. :*****:**: ****: *:*.** * *::*:::*:.***: * *
Mflv_2113|M.gilvum_PYR-GCK YRLVDAATGEFERGYVMVADMVTRQPWD---DTVPVHVTWQKSG------
Mvan_4591|M.vanbaalenii_PYR-1 YRLVDAATGEFERGYVMVADMVTRQPWD---DTVPVHVTWRR--------
MSMEG_5202|M.smegmatis_MC2_155 YRLVDAATGEFERGYVKVADMVTRQPWD---DDVPVHGVHSLSGERREHA
TH_0493|M.thermoresistible__bu YRLVDAATGEFERGYVRVADMVVRQPWD---DTVPVHVTSSTLPTDRDSA
MAB_4552|M.abscessus_ATCC_1997 YRLVDAATGEFESGYVRVADMVNRQPWD---DELPVQVNS----------
MUL_0139|M.ulcerans_Agy99 YRLVDAATGEFERGWVRVSDMVTRQPWA---DDVPVQVQSE---------
Mb1466|M.bovis_AF2122/97 YRIVDAKTGLFEAGYVTVEDMLSRQPWPEPGDEFPVHVTTQRGTPSKP--
Rv1431|M.tuberculosis_H37Rv YRIVDAKTGLFEAGYVTVEDMLSRQPWPEPGDEFPVHVTTQRGTPSKP--
MMAR_2236|M.marinum_M YRIVDAKTGLIEAGYVTVEDMLARQPWPEPGDEFPVHVTTQRAAQ-----
MAV_3343|M.avium_104 YRIVDAKTGLIEAGHVDVASMLSRQPWPEPGDEYPVHVHG----------
**:*** ** :* * * * .*: **** * **:
Mflv_2113|M.gilvum_PYR-GCK -
Mvan_4591|M.vanbaalenii_PYR-1 -
MSMEG_5202|M.smegmatis_MC2_155 -
TH_0493|M.thermoresistible__bu R
MAB_4552|M.abscessus_ATCC_1997 -
MUL_0139|M.ulcerans_Agy99 -
Mb1466|M.bovis_AF2122/97 -
Rv1431|M.tuberculosis_H37Rv -
MMAR_2236|M.marinum_M -
MAV_3343|M.avium_104 -