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EIGIFLMPAHPPERTLYDAAQWDLDIIELADQLGYVEAWVGEHFTVPWEPICAPDLLLAQALLRTKQIKL APGAHLLPYHHPVELAHRVAYFDHLAQGRFMLGVGASGIPGDWALYDVDGKNGEHREMTREALEIMLRIW TEDQPWEHRGKYWNANGIAPMFEGLMRRHIKPYQKPHPPIGVTGFSAGSETLKLAGERGYLPMSLDLNTE YVATHWDAVLEGAARSGRTPDRRDWRLVREVLVAETDEQAFRYAVDGTMGRAMREYVLPTFRMFGMTKFY KHNPSVPDDDMTPEYLAENTFVVGSVDTVVDKLEATYDQVGGFGHLLVLGFDYRENPGPWKESLRLLAEE VMPRLNARIANKPGGPHKPPKPEAAIV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2890 | - | - | 100% (378) | oxygenase |
| M. ulcerans Agy99 | MUL_4194 | - | 4e-38 | 30.19% (371) | monooxygenase |
| M. ulcerans Agy99 | MUL_2949 | - | 5e-34 | 29.23% (366) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1971 | - | 0.0 | 95.33% (364) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4429 | - | 2e-36 | 30.91% (372) | luciferase family protein |
| M. tuberculosis H37Rv | Rv1936 | - | 0.0 | 95.33% (364) | monooxygenase |
| M. leprae Br4923 | MLBr_00348 | - | 5e-12 | 23.81% (273) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0527c | - | 1e-35 | 28.88% (367) | monooxygenase |
| M. marinum M | MMAR_2864 | - | 0.0 | 99.21% (378) | oxygenase |
| M. avium 104 | MAV_0538 | - | 1e-42 | 32.80% (372) | limonene 1,2-monooxygenase |
| M. smegmatis MC2 155 | MSMEG_6107 | - | 7e-43 | 31.54% (371) | limonene 1,2-monooxygenase |
| M. thermoresistible (build 8) | TH_0993 | - | 2e-39 | 31.27% (371) | POSSIBLE MONOOXYGENASE |
| M. vanbaalenii PYR-1 | Mvan_4004 | - | 0.0 | 93.13% (364) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6107|M.smegmatis_MC2_155 --MRPLNFGVFITPFHPAGQSPTTALQYDMDRVEALDRLGYDEAWFGEHH
TH_0993|M.thermoresistible__bu -VARPLNFGVFITPFHPVGQSPTLALEYDLERTVALDRLGYDEVWFGEHH
MAV_0538|M.avium_104 -MSAPLRFGVFITPFHPVGQSPTVALEYDLERVVALDRLGFDEAWFGEHH
MAB_0527c|M.abscessus_ATCC_199 MSAPPLRFGAFITPFHPVGQNPTTALEYDLDRVVALDRLGYHEAWFGEHH
Mflv_4429|M.gilvum_PYR-GCK -----MRFGNFMAPFHPVGQNPTLALERDLDLIVAMDRLGFHEAWVGEHH
MUL_2890|M.ulcerans_Agy99 -----MEIGIFLMPAHPPERTLYDAAQWDLDIIELADQLGYVEAWVGEHF
MMAR_2864|M.marinum_M -----MEIGIFLMPAHPPERTLYDATQWDLDIIELADQLGYVEAWVGEHF
Mb1971|M.bovis_AF2122/97 -----MEIGIFLMPAHPPERTLYDATRWDLDVIELADQLGYVEAWVGEHF
Rv1936|M.tuberculosis_H37Rv -----MEIGIFLMPAHPPERTLYDATRWDLDVIELADQLGYVEAWVGEHF
Mvan_4004|M.vanbaalenii_PYR-1 -----MEIGIFLMPAHPPERSLYDATQWDLEIIELADELGYVEAWVGEHF
MLBr_00348|M.leprae_Br4923 ----MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAW
:. . : . : : *: .: **
MSMEG_6107|M.smegmatis_MC2_155 SGGYELIACPEVFIAAAAERTRHIRLGTGVVSLPYHHPLMVADRWVLLDH
TH_0993|M.thermoresistible__bu SGGYELIASPEVFIAAAAERTRHVRLGTGVVSLPYHHPLMVADRWVLLDH
MAV_0538|M.avium_104 SGGYELIACPEVFIATAAERTKHIRLGTGVVSLPYHHPLMVADRWVLLDH
MAB_0527c|M.abscessus_ATCC_199 SGGYELISCPEVFIATAAERTKHIKLGTGVVSLPYHHPLMVVDRWILLDH
Mflv_4429|M.gilvum_PYR-GCK SAGFEIIASPEVFLGVAAERTKHIRLGTGVSSLPYHHPLMLADRMVLLDH
MUL_2890|M.ulcerans_Agy99 TVPWEPICAPDLLLAQALLRTKQIKLAPGAHLLPYHHPVELAHRVAYFDH
MMAR_2864|M.marinum_M TVPWEPICAPDLLLAQALLRTKQIKLAPGAHLLPYHHPVELAHRVAYFDH
Mb1971|M.bovis_AF2122/97 TVPWEPICAPDLLLAQALLRTQQIKLAPGAHLLPYHHPVELAHRVAYFDH
Rv1936|M.tuberculosis_H37Rv TVPWEPICAPDLLLAQALLRTQQIKLAPGAHLLPYHHPVELAHRVAYFDH
Mvan_4004|M.vanbaalenii_PYR-1 TVPWEPICAPDLLLAQALLRTKSIKLAPGAHLLPYHHPVELAHRVAYLDH
MLBr_00348|M.leprae_Br4923 GS------DAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDH
. :. *: ::*.... *. : * . :**
MSMEG_6107|M.smegmatis_MC2_155 LTRGRVMFGTGPGALPSDAYMMGIDPV--DQRPMMQESLEAILALFRAE-
TH_0993|M.thermoresistible__bu ITRGRVMFGAGPGALPSDAYMMGIDPV--NQRPMMQEALEAILALLRAA-
MAV_0538|M.avium_104 LTRGRVMFGTGPGALPSDAYMMGIDPV--DQRHMMQESLEAILALFRAA-
MAB_0527c|M.abscessus_ATCC_199 ITRGRVIFGTGPGALPTDAYMMGIDPV--DQRRMQEESLEAILALLRAT-
Mflv_4429|M.gilvum_PYR-GCK LTRGRVMLGCGPGQLTSDAHMLGIPAD--EQRPRMEQCLDAIVRLLRG--
MUL_2890|M.ulcerans_Agy99 LAQGRFMLGVGASGIPGDWALYDVDGKNGEHREMTREALEIMLRIWTEDQ
MMAR_2864|M.marinum_M LAQGRFMLGVGASGIPGDWALYDVDGKNGEHREMTREALEIMLRIWTEDQ
Mb1971|M.bovis_AF2122/97 LAQGRFMLGVGASGIPGDWALYDVDGKNGEHREMTREALEIMLRIWTEDE
Rv1936|M.tuberculosis_H37Rv LAQGRFMLGVGASGIPGDWALYDVDGKNGEHREMTREALEIMLRIWTEDE
Mvan_4004|M.vanbaalenii_PYR-1 LAQGRFMLGVGASGIPGDWALFDVDGQNGEHREMTREALEIMLKVWTEDD
MLBr_00348|M.leprae_Br4923 LSGGRHILGLGVSGPQVVEGWYGQPFP--KPLSRTREYIDIVRQVWAREA
:: ** ::* * . . . .: :: : :
MSMEG_6107|M.smegmatis_MC2_155 PGERIDRKTDWFTLR-----DAALHIRPYTWPY-PEISTAAMIS-PSGPR
TH_0993|M.thermoresistible__bu PDERISRETDWFTLR-----DAQLHIRPYTWPY-PEISTAAMIS-PSGPR
MAV_0538|M.avium_104 PTERIDRHSDWFTLR-----DAQLHIRPYTWPY-PEISTAAMIS-PSGPR
MAB_0527c|M.abscessus_ATCC_199 PQERINRETSWFTLR-----DAQLQLRPYTHPY-PEILTAAMFS-PSGPR
Mflv_4429|M.gilvum_PYR-GCK --ETVTMHTDGFTLQ-----DARLQLKPYSEPC-FDIAVAASFS-PTGPR
MUL_2890|M.ulcerans_Agy99 PWEHRGKYWNANGIAPMFEGLMRRHIKPYQKPH-PPIGVTGFSAGSETLK
MMAR_2864|M.marinum_M PWEHRGKYWNANGIAPMFEGLMRRHIKPYQKPH-PPIGVTGFSAGSETLK
Mb1971|M.bovis_AF2122/97 PWEHRGKYWNANGIAPMFEGLMRRHIKPYQKPH-PPIGVTGFSAGSETLK
Rv1936|M.tuberculosis_H37Rv PWEHRGKYWNANGIAPMFEGLMRRHIKPYQKPH-PPIGVTGFSAGSETLK
Mvan_4004|M.vanbaalenii_PYR-1 PWEFRGKYWNANGIAPMFEGLMRRHIKPFQAPH-PPIGVTGFSAGSETLK
MLBr_00348|M.leprae_Br4923 PVVSDGQHYP-LPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVA
: ::* * * .
MSMEG_6107|M.smegmatis_MC2_155 LAGKLGTSLLSLSMSVPGGYAAVETTWNVVRDEAAAAGRPEPDRENWRVL
TH_0993|M.thermoresistible__bu LAGSLGTSLLSLSMSVPGGYAAVENTWDVVVQQAAKAGRPEPDRANWRVL
MAV_0538|M.avium_104 LAGALGTSLLSLSMSVPGGYAALETTWDVVREQAAKAGRDEPDRGDWRVL
MAB_0527c|M.abscessus_ATCC_199 LAGKLGAGLLSLSASIPGGFAALENAWEVVREQAEIHGHPEPDRSSWRVL
Mflv_4429|M.gilvum_PYR-GCK GAGRHGIGMLSIAATARQGMDLLAQHWNTWDEVAREHGH-QADRSKWRLV
MUL_2890|M.ulcerans_Agy99 LAGERGYLPMSLDLNT----EYVATHWDAVLEGAARSGR-TPDRRDWRLV
MMAR_2864|M.marinum_M LAGERGYLPMSLDLNT----EYVATHWDAVLEGAARSGR-TPDRRDWRLV
Mb1971|M.bovis_AF2122/97 LAGERGYIPMSLDLNT----EYVATHWDAVEEGALRSGR-TPDRRDWRLV
Rv1936|M.tuberculosis_H37Rv LAGERGYIPMSLDLNT----EYVATHWDAVEEGALRSGR-TPDRRDWRLV
Mvan_4004|M.vanbaalenii_PYR-1 LAGERGYLPMSLDLNT----DYVATHWDAVLEGAARSGR-TPDRRDWRLV
MLBr_00348|M.leprae_Br4923 LAAEICDGWLPIFFSP-----RMADMYNEWLDEGFARTGARRSREDFEIC
*. :.: . : :: : . .* .:.:
MSMEG_6107|M.smegmatis_MC2_155 GIVHLADTREQAIEDCTYGLQ--DFANYFGAAGFVPLSNQAEGGG---TP
TH_0993|M.thermoresistible__bu GIVHLADTREQALQDCTYGLQ--DFANYFGAAGFVPLANEVAGGQ---SP
MAV_0538|M.avium_104 SIMHIADSREQAIDDCTYGLQ--DFANYFGAAGFVPLANSVEGTQ---TP
MAB_0527c|M.abscessus_ATCC_199 GIMHLAETRDQAIADCTYGLP--DYAHYFGAVGVLPLANSADGADGAIDP
Mflv_4429|M.gilvum_PYR-GCK GPMHLAETREQAERDVEYGIA--EFSRYF--THILPSG-PVQGDT----P
MUL_2890|M.ulcerans_Agy99 REVLVAETDEQAFRYAVDGTMGRAMREYVLPTFRMFGMTKFYKHNPSVPD
MMAR_2864|M.marinum_M REVLVAETDEQAFRYAVDGTMGRAMREYVLPTFRMFGMTKFYKHNPSVPD
Mb1971|M.bovis_AF2122/97 REVLVAETDEQAFRYAVDGTMGRAMREYVLPTFRMFGMTKFYKHNPSVPD
Rv1936|M.tuberculosis_H37Rv REVLVAETDEQAFRYAVDGTMGRAMREYVLPTFRMFGMTKFYKHNPSVPD
Mvan_4004|M.vanbaalenii_PYR-1 REVVVAETDEQAFRYAVDGMMGRNMREYVLPTFRMFGMTKFYKHNPSVPD
MLBr_00348|M.leprae_Br4923 ASAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVV
:. : ::* .
MSMEG_6107|M.smegmatis_MC2_155 YEFVENYASKGNCCIGTPDDAIVYIQDLLDRS-GGFGTFLLLGHDWAP-P
TH_0993|M.thermoresistible__bu REFVEAYAEKGNCCIGTPGDAIVYLSDLLERS-GGFGTFLMLGHDWAS-P
MAV_0538|M.avium_104 HEFVAEYAAKGNCCIGTPEDAIAHIEDLLDRS-GGFGTLLMLGHDWAS-P
MAB_0527c|M.abscessus_ATCC_199 HEFVKAYADEGNCCIGTPEDAIEYIQGLLDTS-GGFGTFLMLGHDWAA-P
Mflv_4429|M.gilvum_PYR-GCK EEIIANNRQSGFAVIGTPDDAIAKISELVEASDGGFGAFLLFDHDWAP-P
MUL_2890|M.ulcerans_Agy99 DDMTPEYLAENTFVVGSVDTVVDKLEATYDQV-GGFGHLLVLGFDYRENP
MMAR_2864|M.marinum_M DDVTPEYLAENTFVVGSVDTVVDKLEATYDQV-GGFGHLLVLGFDYRENP
Mb1971|M.bovis_AF2122/97 DEVTPEYLAENTFVVGSVQTVVDKLEATYDQV-GGFGHLLILGFDYSDNP
Rv1936|M.tuberculosis_H37Rv DEVTPEYLAENTFVVGSVQTVVDKLEATYDQV-GGFGHLLILGFDYSDNP
Mvan_4004|M.vanbaalenii_PYR-1 DDVTPEYLAENTFVVGSVETVVDKLEATYDQV-GGFGHLLILGFDYRDDP
MLBr_00348|M.leprae_Br4923 DEVTALFRSN------QKDKAAEIIPNELVDS-----TMIVGDVDYVCKQ
:. . . : ::: . *:
MSMEG_6107|M.smegmatis_MC2_155 AATFHSYELFAREVIPHFKGQLTAARASHDWAKGMRDQLLGRAGQAIVNA
TH_0993|M.thermoresistible__bu QATYHSYELFAREVIPHFKGQLTAPRASHDWAKQMRGQLLGRAGEAIVKA
MAV_0538|M.avium_104 EATYHCYDLMARKVIPHFKRQLDASRASHDWAKGMRDQLLGRAGEAVVKA
MAB_0527c|M.abscessus_ATCC_199 EATFKSYELFARKVIPHFTGQLTAAQASHDWAQAKRGELLGRAGDAVAKA
Mflv_4429|M.gilvum_PYR-GCK AAKLRSYELFAQYVIPHFTGQLSAPIASRDWVTESGRVFVDQATHAIGRA
MUL_2890|M.ulcerans_Agy99 GPWKESLRLLAEEVMPRLNARIANKPGGPHKPPKPEAAIV----------
MMAR_2864|M.marinum_M GPWKESLRLLAEEVMPRLNARIAKKPGGPHKPPKPEAAIV----------
Mb1971|M.bovis_AF2122/97 GPWKESLRLLAHEVMPRLNARLATKP---------ATAVV----------
Rv1936|M.tuberculosis_H37Rv GPWKESLRLLAHEVMPRLNARLATKP---------ATAVV----------
Mvan_4004|M.vanbaalenii_PYR-1 GPWKESMRLLAEEVMPRLNARIAKKP---------RIALV----------
MLBr_00348|M.leprae_Br4923 IAAWSAAGVTMMMVSASSVEQVRDLAGLF---------------------
. . : * . ::
MSMEG_6107|M.smegmatis_MC2_155 ITEHTQAHPAENEN---
TH_0993|M.thermoresistible__bu IGEHTSEQEQR------
MAV_0538|M.avium_104 ISEHVDEHKDAVH----
MAB_0527c|M.abscessus_ATCC_199 IGEHVAQKASH------
Mflv_4429|M.gilvum_PYR-GCK IESHAAEQQAKQSRTSD
MUL_2890|M.ulcerans_Agy99 -----------------
MMAR_2864|M.marinum_M -----------------
Mb1971|M.bovis_AF2122/97 -----------------
Rv1936|M.tuberculosis_H37Rv -----------------
Mvan_4004|M.vanbaalenii_PYR-1 -----------------
MLBr_00348|M.leprae_Br4923 -----------------