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M. ulcerans Agy99 MUL_2852 (spoU)

annotation: tRNA/rRNA methyltransferase SpoU
coordinates: 3180083 - 3180547
length: 154

VFKLLFYSPRIAPNTGNAIRTAAATGCELHLVEPLGFDLSEPKLRRAGLDYHDLASVTVHGSLTQAWDAL
LPARVFAFTAGASVTFSDVDFRPGDVLMFGPEPTGLHAATLADAHITQQVRIPMLAGRRSLNLANAAAVA
VYEAWRQHGYPGAL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_2852spoU-100% (154)tRNA/rRNA methyltransferase SpoU
M. ulcerans Agy99MUL_1630tsnR3e-0832.85% (137) 23S rRNA methyltransferase TsnR
M. ulcerans Agy99MUL_0269-5e-0534.27% (143) rRNA methyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3401spoU3e-7183.12% (154) tRNA/rRNA methylase SpoU
M. gilvum PYR-GCKMflv_4891-9e-6979.87% (154) tRNA/rRNA methyltransferase (SpoU)
M. tuberculosis H37RvRv3366spoU3e-7183.12% (154) tRNA/rRNA methylase SpoU
M. leprae Br4923MLBr_00419-8e-7080.92% (152) putative tRNA/rRNA methyltransferase
M. abscessus ATCC 19977MAB_3702-1e-6170.78% (154) tRNA/rRNA methyltransferase SpoU
M. marinum MMMAR_1163spoU2e-8599.35% (154) tRNA/rRNA methyltransferase SpoU
M. avium 104MAV_4333-2e-7283.66% (153) RNA methyltransferase, TrmH family protein, group 2
M. smegmatis MC2 155MSMEG_1636-4e-7078.57% (154) RNA methyltransferase, TrmH family protein, group 2
M. thermoresistible (build 8)TH_2120spoU3e-6375.82% (153) PROBABLE tRNA/rRNA METHYLASE SPOU (tRNA/rRNA
M. vanbaalenii PYR-1Mvan_1533-2e-7081.82% (154) tRNA/rRNA methyltransferase (SpoU)

CLUSTAL 2.0.9 multiple sequence alignment


MUL_2852|M.ulcerans_Agy99           --------------MFKLLFYSPRIAPNTGNAIRTAAATGCELHLVEPLG
MMAR_1163|M.marinum_M               --------------MFKLLFYSPRIAPNTGNAIRTAAATGCELHLVEPLG
MAV_4333|M.avium_104                --------------MFKLMFVSPRIAPNTGNAIRTAAATGCELHLVEPMG
Mb3401|M.bovis_AF2122/97            --------------MFRLLFVSPRIAPNTGNAIRTCAATGCELHLVEPLG
Rv3366|M.tuberculosis_H37Rv         --------------MFRLLFVSPRIAPNTGNAIRTCAATGCELHLVEPLG
MLBr_00419|M.leprae_Br4923          ----------MISKMFRLLFYTPRIPPNTGNAIRTAAVTGCALHLVEPIG
Mflv_4891|M.gilvum_PYR-GCK          --------------MFNVLFYSPRIAPNTGNAIRMVAGTGCALHLVEPLG
Mvan_1533|M.vanbaalenii_PYR-1       --------------MFKVMFYSPRIAPNTGNAIRMVAGTGCELHLVEPLG
MSMEG_1636|M.smegmatis_MC2_155      --------------MFRVMFFSPRIAPNTGNAIRMVAATGCELHLVHPLG
TH_2120|M.thermoresistible__bu      VCEQSPIAGWDHRLVFRVMFYSPRIPPNTGNAIRMVAATGAELHLVDPL-
MAB_3702|M.abscessus_ATCC_1997      --------------MFHILFHEPRIAPNTGNAIRMVAGTGCELHLVQPL-
                                                  :*.::*  ***.********  * **. ****.*: 

MUL_2852|M.ulcerans_Agy99           FDLSEPKLRRAGLDYHDLASVTVHGSLTQAWDALLPARVFAFTAGASVTF
MMAR_1163|M.marinum_M               FDLSEPKLRRAGLDYHDLASVTVHGSLTQAWDALLPARVFAFTAGASVTF
MAV_4333|M.avium_104                FDLSEPKLRRAGLDYHDLASVTVHASLAAAWDALTPARVVAFTSHAPASF
Mb3401|M.bovis_AF2122/97            FDLSEPKLRRAGLDYHDLASVTVHASLAHAWEALSPARVFAFTAQATTLF
Rv3366|M.tuberculosis_H37Rv         FDLSEPKLRRAGLDYHDLASVTVHASLAHAWEALSPARVFAFTAQATTLF
MLBr_00419|M.leprae_Br4923          FDLSNPKLRRAGLDYHDLASVTVHTSLSEAWNALSPARVFAFSTLANTLF
Mflv_4891|M.gilvum_PYR-GCK          FDLSEPKLRRAGLDYHDLASVTVHADLGAAWSVLMPARVFAFTAHAATSF
Mvan_1533|M.vanbaalenii_PYR-1       FDLSEPKLRRAGLDYHDLASVTVHPDLDSAWAAVTPARVFAFTAHATASF
MSMEG_1636|M.smegmatis_MC2_155      FDLSEPKLRRAGLDYHDLASVTVHDDLPSAWQALMPARVYVFTAHASTPF
TH_2120|M.thermoresistible__bu      FDLSEPKLRRAGLDYHDLASVSVHTDLDAAWAALQPRRVFAFTVRAETTY
MAB_3702|M.abscessus_ATCC_1997      FDLSEAKVRRAGLDYHDMASVTVHENLSAAWKTLKPQRVYAFTAHASVTY
                                    ****:.*:*********:***:** .*  ** .: * ** .*:  * . :

MUL_2852|M.ulcerans_Agy99           SDVDFRPGDVLMFGPEPTGLHAATLADAHITQQVRIPMLAGRRSLNLANA
MMAR_1163|M.marinum_M               SDVDFRPGDVLMFGPEPTGLDAATLADAHITQQVRIPMLAGRRSLNLANA
MAV_4333|M.avium_104                AELRYRPGDVLMFGPEPTGLDAATLADPHVTTQVRIPMLAGRRSLNLSNA
Mb3401|M.bovis_AF2122/97            TNVGYRAGDVLMFGPEPTGLDEATLADTHITGQVRIPMLAGRRSLNLSNA
Rv3366|M.tuberculosis_H37Rv         TNVGYRAGDVLMFGPEPTGLDEATLADTHITGQVRIPMLAGRRSLNLSNA
MLBr_00419|M.leprae_Br4923          TDVSYQAGDVLMFGPEPTGLDAATLADDHITQQVRIPMLSGRRSLNLSNA
Mflv_4891|M.gilvum_PYR-GCK          AGVGYEPGDVLMFGPEPTGLDEATLADPHITGQVRIPMLSGRRSLNLSNA
Mvan_1533|M.vanbaalenii_PYR-1       ADVAYRPGDVLMFGPEPTGLDAATLADPHITAQVRIPLLAGRRSLNLSNA
MSMEG_1636|M.smegmatis_MC2_155      TDIAYRPGDVLMFGPEPTGLDEQTLADPHITEQIRIPMLAGRRSLNLSNA
TH_2120|M.thermoresistible__bu      VDIHYQPGDVLMFGPEPTGLDAETLADPHITAEVSIPMLPGRRSLNLSNA
MAB_3702|M.abscessus_ATCC_1997      TDIAYQPGDVLLFGPEPTGLDAEVLADPHITEKVRIPLLPGRRSLNLSNA
                                      : :..****:********.  .*** *:* :: **:*.*******:**

MUL_2852|M.ulcerans_Agy99           AAVAVYEAWRQHGYPGAL
MMAR_1163|M.marinum_M               AAVAVYEAWRQHGYPGAL
MAV_4333|M.avium_104                AAIAVYEAWRQHGYAGAT
Mb3401|M.bovis_AF2122/97            AAVAVYEAWRQHGFAGAV
Rv3366|M.tuberculosis_H37Rv         AAVAVYEAWRQHGFAGAV
MLBr_00419|M.leprae_Br4923          AAVAVYEAWRQHGYAGLV
Mflv_4891|M.gilvum_PYR-GCK          AAVAVYEAWRQHGFAGAV
Mvan_1533|M.vanbaalenii_PYR-1       AAVAVYEAWRQQGFSGAV
MSMEG_1636|M.smegmatis_MC2_155      AAVAAYEAWRQHGFPGAV
TH_2120|M.thermoresistible__bu      AAVAVYEAWRQHGFAGA-
MAB_3702|M.abscessus_ATCC_1997      AAIAAYEAWRQHDFAGSV
                                    **:*.******:.:.*