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VHESERSRPTGPAQILTERSARVSAAAKLQRHVGRRRTSRFLAEGPNLVEAAAARGLIRELYVTEAAEQR HEPLLARQDAPVYVVTERAAKALSDTVTPSGLVAVCEMPTTGLAEVLSGAPRLVAVAVEIGEPGNAGTLI RIADAMGANAVVLAGNSVDPYNGKCLRASAGSIFAIPVIVAPDTSAALGALRGAGLQALASVLDGEKSLD DIDQLLEAPTAWLFGPEAHGLSAEVAAAAHHRVRIPMSGGAESLNVAAAAAICLYQSARALSSDR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_1630 | tsnR | - | 100% (275) | 23S rRNA methyltransferase TsnR |
M. ulcerans Agy99 | MUL_0269 | - | 2e-20 | 31.90% (232) | rRNA methyltransferase |
M. ulcerans Agy99 | MUL_4155 | - | 7e-14 | 29.81% (161) | tRNA/rRNA methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1671 | tsnR | 1e-108 | 75.88% (257) | 23S rRNA methyltransferase TsnR |
M. gilvum PYR-GCK | Mflv_3539 | - | 8e-90 | 70.16% (248) | tRNA/rRNA methyltransferase (SpoU) |
M. tuberculosis H37Rv | Rv1644 | tsnR | 1e-107 | 75.49% (257) | 23S rRNA methyltransferase TsnR |
M. leprae Br4923 | MLBr_01397 | tsnR | 2e-97 | 70.04% (257) | putative rRNA methyltransferase |
M. abscessus ATCC 19977 | MAB_2324 | - | 5e-75 | 60.66% (244) | tRNA/rRNA methyltransferase |
M. marinum M | MMAR_2451 | tsnR | 1e-150 | 99.64% (275) | 23S rRNA methyltransferase TsnR |
M. avium 104 | MAV_3123 | - | 1e-108 | 74.32% (257) | TsnR protein |
M. smegmatis MC2 155 | MSMEG_3790 | - | 3e-89 | 68.80% (250) | RNA methyltransferase, TrmH family protein |
M. thermoresistible (build 8) | TH_1588 | tsnR | 4e-94 | 70.72% (263) | Possible 23S rRNA methyltransferase tsnR |
M. vanbaalenii PYR-1 | Mvan_3325 | - | 2e-88 | 68.95% (248) | tRNA/rRNA methyltransferase (SpoU) |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3539|M.gilvum_PYR-GCK ----------------------MAAAVKLHRHTGRRRAARFLAEGPNLVE Mvan_3325|M.vanbaalenii_PYR-1 ----------------------MAAAVKLHRHTGRRRAARFLAEGPNLVE MSMEG_3790|M.smegmatis_MC2_155 ----------------------MVAAVKLHRHVGRRRAARFLAEGPNLVE MUL_1630|M.ulcerans_Agy99 MHESERSRPTGPAQILTERSARVSAAAKLQRHVGRRRTSRFLAEGPNLVE MMAR_2451|M.marinum_M MHESERSRPTGPAQILTERSARVSAAAKLQRHVGRRRTSRFLAEGPNLVE Mb1671|M.bovis_AF2122/97 --------------MLTERSARVATAVKLHRHVGRRRAGRFLAEGPNLVA Rv1644|M.tuberculosis_H37Rv --------------MLTERSARVATAVKLHRHVGRRRAGRFLAEGPNLVA MLBr_01397|M.leprae_Br4923 --------------MLTERSARVVAAVKLHRQVARRRVRRFLAEGPNLVE MAV_3123|M.avium_104 --------------MLTERSGRVAAAAKLHRHVGRRRAARFLAEGPNLVE TH_1588|M.thermoresistible__bu --------------LLTERSARVVAAVKLHRQTARRRAARFLAEGPNLVE MAB_2324|M.abscessus_ATCC_1997 ----------------------MIDAVKLHRPAARRRAGLFLAEGPNLVE : *.**:* ..***. ********* Mflv_3539|M.gilvum_PYR-GCK AALRRGLVSEVFATESAADRFGPLLA----GAPVHLVTEKAAKALSDTVT Mvan_3325|M.vanbaalenii_PYR-1 AALRRGLVHEVFATEGAAAKFAALLG----AASVHLVTDKAAKALSDTVT MSMEG_3790|M.smegmatis_MC2_155 AALRRGLVSEVFATEAALDRFGALLA----DAPVTPVTERAAKALSDTVT MUL_1630|M.ulcerans_Agy99 AAAARGLIRELYVTEAAEQRHEPLLA--RQDAPVYVVTERAAKALSDTVT MMAR_2451|M.marinum_M AAAARGLIRELYVTEAAEQRHEPLLA--RQDAPVYVVTERAAKALSDTVT Mb1671|M.bovis_AF2122/97 AALARGLVREVFVTEVAARRHELLLA--AHEASVHLVTERAAKALSDTVT Rv1644|M.tuberculosis_H37Rv AALARGLVREVFVTEVAARRHELLLA--AHEASVHLVTERAAKALSDTVT MLBr_01397|M.leprae_Br4923 AAIVSGLVRDVFVTEVAAQRHATVLA--TLKCPVHPVSERAAKALSDTVT MAV_3123|M.avium_104 AAAGRGLVRDVFVTEAAQQRYAPLLA--ALDCPVHLITERAAKALSDTVT TH_1588|M.thermoresistible__bu AALRRGLVSEVYATEAAAQRFAELLAGTPADVGVRLVTERAAKALSDTVT MAB_2324|M.abscessus_ATCC_1997 AALRSGAVERIFATDAAIERFVDLLA----EAPVRRVTERAAKALSDTVT ** * : ::.*: * :. :*. * ::::********** Mflv_3539|M.gilvum_PYR-GCK PVGLVAVCTLPEVDLTEVLAGEPTLVAVPVGISEPGNAGTVIRVADAMGA Mvan_3325|M.vanbaalenii_PYR-1 PVGLVAVCSIPEADLDQVLAGNPKLVAVPVGISEPGNAGTLIRVADAMGA MSMEG_3790|M.smegmatis_MC2_155 PVGLVAVCRLPEVSLDDVLAGPAGLIAVPVQLSEPGNAGTLIRVADAMGA MUL_1630|M.ulcerans_Agy99 PSGLVAVCEMPTTGLAEVLSGAPRLVAVAVEIGEPGNAGTLIRIADAMGA MMAR_2451|M.marinum_M PSGLVAVCEMPTTGLAEVLSGAPRLVAVAVEIGEPGNAGTLIRIADAMGA Mb1671|M.bovis_AF2122/97 PAGLVAVCDLPATRLEDVLAGSPQLIAVTVEIREPGNAGTVIRIADAMGA Rv1644|M.tuberculosis_H37Rv PAGLVAVCDLPATRLEDVLAGSPQLIAVTVEIREPGNAGTVIRIADAMGA MLBr_01397|M.leprae_Br4923 PTGLIAVCEMPTTRLATVLAGSPQLVVAAVEISEPGNAGTVIRIADAMGA MAV_3123|M.avium_104 PAGLVAVCDLPATGLRDVLAGSPRLIAVAVQISEPGNAGTLIRLSDAMGA TH_1588|M.thermoresistible__bu PVGLVAVCRMPQTTLADVLAAAPRLVAVGVQIGEPGNAGTLIRTADAMGA MAB_2324|M.abscessus_ATCC_1997 PVGLVAQCRTVVSTWSQVTARSPRFVIVAVDISEPGNAGTLIRVADAMGA * **:* * * : . :: . * : *******:** :***** Mflv_3539|M.gilvum_PYR-GCK DAVVLAGDSVDPYNGKCLRASAGSIFSIPVISHHDAADVVTQLKDAGLQV Mvan_3325|M.vanbaalenii_PYR-1 DAVVLAGDSVDPYNGKCLRASAGSIFSIPVLSAPDAVAAVTKLKDAGLQV MSMEG_3790|M.smegmatis_MC2_155 AAVVLAGNSVDPYNSKCLRASAGSIFSIPVISDPDEARVVQRLRDAGLRV MUL_1630|M.ulcerans_Agy99 NAVVLAGNSVDPYNGKCLRASAGSIFAIPVIVAPDTSAALGALRGAGLQA MMAR_2451|M.marinum_M NAVVLAGNSVDPYNGKCLRASAGSIFAIPVIVAPDTSAALGALRGAGLQV Mb1671|M.bovis_AF2122/97 AAVILAGRSVDPYNGKCLRASTGSIFAIPVVVAPDVGAAIADLRAAGLQV Rv1644|M.tuberculosis_H37Rv AAVILAGRSVDPYNGKCLRASTGSIFAIPVVVAPDVGAAIADLRAAGLQV MLBr_01397|M.leprae_Br4923 AAVIFGGYTVDPYNGKCLRSSAGSIFSITVVVASDAYAAVTELRAAGLQV MAV_3123|M.avium_104 AGVLLAGHSVDPYNGKCLRASAGSIFSVPVVAAPDLREAVAAVREAGLQL TH_1588|M.thermoresistible__bu DAVVLAGAGVDPYNSKCLRASAGAIFTIPVVAGPDPVETVGRLQASGLQV MAB_2324|M.abscessus_ATCC_1997 DAVVLAGNSVDPFNGKSLRASAGSIFNIPVVPEGDVGAIAADLAQTGVAL .*::.* ***:*.*.**:*:*:** :.*: * : :*: Mflv_3539|M.gilvum_PYR-GCK LATVLGGSVSLDE----VDLSGPTAWLFGPEAHGLPAEVAALATAGVEIP Mvan_3325|M.vanbaalenii_PYR-1 LATVLDGPVSLED----ADLSVPTAWLFGPEAHGLPADVAGLATAGVRIP MSMEG_3790|M.smegmatis_MC2_155 LATTVDGEADLDDPDLEAELTEPTAWLFGPEAHGLSTDLAAMAHRRVQIP MUL_1630|M.ulcerans_Agy99 LASVLDGEKSLDDID--QLLEAPTAWLFGPEAHGLSAEVAAAAHHRVRIP MMAR_2451|M.marinum_M LASVLDGEKSLDDID--QLLEAPTAWLFGPEAHGLSAEVAAAAHHRVRIP Mb1671|M.bovis_AF2122/97 LATAVDGEMALDDAD--RLLAEPTAWLFGPEAHGLSAEIAALADHRVHIP Rv1644|M.tuberculosis_H37Rv LATAVDGEMALDDAD--RLLAEPTAWLFGPEAHGLSAEIAALADHRVHIL MLBr_01397|M.leprae_Br4923 LATMVDGETSLDEAK--PLLGKPTAWLFGSEPHGLSTEIAEAADYRVRIP MAV_3123|M.avium_104 LATTVDGEVRLDRAG--ELLAKPTAWLFGPESHGLPSEVAAAADHRVRIP TH_1588|M.thermoresistible__bu LATTLDGEISLDSAESHVNLDRPTAWLFGGEAHGLPPEVAAAADHRVHIP MAB_2324|M.abscessus_ATCC_1997 LATTLDGDLSLDEAD--AVLAGPCAWFFGNEAHGLDGATAALATHRINIP **: :.* *: * * **:** *.*** * * :.* Mflv_3539|M.gilvum_PYR-GCK MTGGAESLNVASAAAICLYQSAAAHRRAASST Mvan_3325|M.vanbaalenii_PYR-1 MPGNAESLNVASAAAICLYQSARSQAPV---- MSMEG_3790|M.smegmatis_MC2_155 MPGHAESLNIASAASICLYQSARAQRRR---- MUL_1630|M.ulcerans_Agy99 MSGGAESLNVAAAAAICLYQSARALSSDR--- MMAR_2451|M.marinum_M MSGGAESLNVAAAAAICLYQSARALSSDR--- Mb1671|M.bovis_AF2122/97 MSGGAESLNVAAAAAICLYESARALGRR---- Rv1644|M.tuberculosis_H37Rv MSGGAESLNVAAAAAICLYESARALGRR---- MLBr_01397|M.leprae_Br4923 MVGGVESLNVAATAAICLYQSSRALRL----- MAV_3123|M.avium_104 MAGGAESLNVASAAAICLYQSARALELFMRP- TH_1588|M.thermoresistible__bu MAGRTESLNVAAAAAICLYQSARAARSADHPA MAB_2324|M.abscessus_ATCC_1997 MRGGAESLNLASAASICLYATARMHRRQ---- * * .****:*::*:**** ::