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M. gilvum PYR-GCK Mflv_4891 (-)

annotation: tRNA/rRNA methyltransferase (SpoU)
coordinates: 5211491 - 5211955
length: 154

VFNVLFYSPRIAPNTGNAIRMVAGTGCALHLVEPLGFDLSEPKLRRAGLDYHDLASVTVHADLGAAWSVL
MPARVFAFTAHAATSFAGVGYEPGDVLMFGPEPTGLDEATLADPHITGQVRIPMLSGRRSLNLSNAAAVA
VYEAWRQHGFAGAV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4891--100% (154)tRNA/rRNA methyltransferase (SpoU)
M. gilvum PYR-GCKMflv_3539-2e-0529.50% (139) tRNA/rRNA methyltransferase (SpoU)
M. gilvum PYR-GCKMflv_1715-4e-0544.23% (52) tRNA/rRNA methyltransferase (SpoU)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3401spoU2e-7285.06% (154) tRNA/rRNA methylase SpoU
M. tuberculosis H37RvRv3366spoU2e-7285.06% (154) tRNA/rRNA methylase SpoU
M. leprae Br4923MLBr_00419-8e-6879.22% (154) putative tRNA/rRNA methyltransferase
M. abscessus ATCC 19977MAB_3702-5e-6674.68% (154) tRNA/rRNA methyltransferase SpoU
M. marinum MMMAR_1163spoU2e-6980.52% (154) tRNA/rRNA methyltransferase SpoU
M. avium 104MAV_4333-5e-7181.70% (153) RNA methyltransferase, TrmH family protein, group 2
M. smegmatis MC2 155MSMEG_1636-5e-7382.47% (154) RNA methyltransferase, TrmH family protein, group 2
M. thermoresistible (build 8)TH_2120spoU1e-6779.74% (153) PROBABLE tRNA/rRNA METHYLASE SPOU (tRNA/rRNA
M. ulcerans Agy99MUL_2852spoU7e-6979.87% (154) tRNA/rRNA methyltransferase SpoU
M. vanbaalenii PYR-1Mvan_1533-2e-7586.36% (154) tRNA/rRNA methyltransferase (SpoU)

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1163|M.marinum_M               --------------MFKLLFYSPRIAPNTGNAIRTAAATGCELHLVEPLG
MUL_2852|M.ulcerans_Agy99           --------------MFKLLFYSPRIAPNTGNAIRTAAATGCELHLVEPLG
MAV_4333|M.avium_104                --------------MFKLMFVSPRIAPNTGNAIRTAAATGCELHLVEPMG
Mb3401|M.bovis_AF2122/97            --------------MFRLLFVSPRIAPNTGNAIRTCAATGCELHLVEPLG
Rv3366|M.tuberculosis_H37Rv         --------------MFRLLFVSPRIAPNTGNAIRTCAATGCELHLVEPLG
MLBr_00419|M.leprae_Br4923          ----------MISKMFRLLFYTPRIPPNTGNAIRTAAVTGCALHLVEPIG
Mflv_4891|M.gilvum_PYR-GCK          --------------MFNVLFYSPRIAPNTGNAIRMVAGTGCALHLVEPLG
Mvan_1533|M.vanbaalenii_PYR-1       --------------MFKVMFYSPRIAPNTGNAIRMVAGTGCELHLVEPLG
MSMEG_1636|M.smegmatis_MC2_155      --------------MFRVMFFSPRIAPNTGNAIRMVAATGCELHLVHPLG
TH_2120|M.thermoresistible__bu      VCEQSPIAGWDHRLVFRVMFYSPRIPPNTGNAIRMVAATGAELHLVDPL-
MAB_3702|M.abscessus_ATCC_1997      --------------MFHILFHEPRIAPNTGNAIRMVAGTGCELHLVQPL-
                                                  :*.::*  ***.********  * **. ****.*: 

MMAR_1163|M.marinum_M               FDLSEPKLRRAGLDYHDLASVTVHGSLTQAWDALLPARVFAFTAGASVTF
MUL_2852|M.ulcerans_Agy99           FDLSEPKLRRAGLDYHDLASVTVHGSLTQAWDALLPARVFAFTAGASVTF
MAV_4333|M.avium_104                FDLSEPKLRRAGLDYHDLASVTVHASLAAAWDALTPARVVAFTSHAPASF
Mb3401|M.bovis_AF2122/97            FDLSEPKLRRAGLDYHDLASVTVHASLAHAWEALSPARVFAFTAQATTLF
Rv3366|M.tuberculosis_H37Rv         FDLSEPKLRRAGLDYHDLASVTVHASLAHAWEALSPARVFAFTAQATTLF
MLBr_00419|M.leprae_Br4923          FDLSNPKLRRAGLDYHDLASVTVHTSLSEAWNALSPARVFAFSTLANTLF
Mflv_4891|M.gilvum_PYR-GCK          FDLSEPKLRRAGLDYHDLASVTVHADLGAAWSVLMPARVFAFTAHAATSF
Mvan_1533|M.vanbaalenii_PYR-1       FDLSEPKLRRAGLDYHDLASVTVHPDLDSAWAAVTPARVFAFTAHATASF
MSMEG_1636|M.smegmatis_MC2_155      FDLSEPKLRRAGLDYHDLASVTVHDDLPSAWQALMPARVYVFTAHASTPF
TH_2120|M.thermoresistible__bu      FDLSEPKLRRAGLDYHDLASVSVHTDLDAAWAALQPRRVFAFTVRAETTY
MAB_3702|M.abscessus_ATCC_1997      FDLSEAKVRRAGLDYHDMASVTVHENLSAAWKTLKPQRVYAFTAHASVTY
                                    ****:.*:*********:***:** .*  ** .: * ** .*:  * . :

MMAR_1163|M.marinum_M               SDVDFRPGDVLMFGPEPTGLDAATLADAHITQQVRIPMLAGRRSLNLANA
MUL_2852|M.ulcerans_Agy99           SDVDFRPGDVLMFGPEPTGLHAATLADAHITQQVRIPMLAGRRSLNLANA
MAV_4333|M.avium_104                AELRYRPGDVLMFGPEPTGLDAATLADPHVTTQVRIPMLAGRRSLNLSNA
Mb3401|M.bovis_AF2122/97            TNVGYRAGDVLMFGPEPTGLDEATLADTHITGQVRIPMLAGRRSLNLSNA
Rv3366|M.tuberculosis_H37Rv         TNVGYRAGDVLMFGPEPTGLDEATLADTHITGQVRIPMLAGRRSLNLSNA
MLBr_00419|M.leprae_Br4923          TDVSYQAGDVLMFGPEPTGLDAATLADDHITQQVRIPMLSGRRSLNLSNA
Mflv_4891|M.gilvum_PYR-GCK          AGVGYEPGDVLMFGPEPTGLDEATLADPHITGQVRIPMLSGRRSLNLSNA
Mvan_1533|M.vanbaalenii_PYR-1       ADVAYRPGDVLMFGPEPTGLDAATLADPHITAQVRIPLLAGRRSLNLSNA
MSMEG_1636|M.smegmatis_MC2_155      TDIAYRPGDVLMFGPEPTGLDEQTLADPHITEQIRIPMLAGRRSLNLSNA
TH_2120|M.thermoresistible__bu      VDIHYQPGDVLMFGPEPTGLDAETLADPHITAEVSIPMLPGRRSLNLSNA
MAB_3702|M.abscessus_ATCC_1997      TDIAYQPGDVLLFGPEPTGLDAEVLADPHITEKVRIPLLPGRRSLNLSNA
                                      : :..****:********.  .*** *:* :: **:*.*******:**

MMAR_1163|M.marinum_M               AAVAVYEAWRQHGYPGAL
MUL_2852|M.ulcerans_Agy99           AAVAVYEAWRQHGYPGAL
MAV_4333|M.avium_104                AAIAVYEAWRQHGYAGAT
Mb3401|M.bovis_AF2122/97            AAVAVYEAWRQHGFAGAV
Rv3366|M.tuberculosis_H37Rv         AAVAVYEAWRQHGFAGAV
MLBr_00419|M.leprae_Br4923          AAVAVYEAWRQHGYAGLV
Mflv_4891|M.gilvum_PYR-GCK          AAVAVYEAWRQHGFAGAV
Mvan_1533|M.vanbaalenii_PYR-1       AAVAVYEAWRQQGFSGAV
MSMEG_1636|M.smegmatis_MC2_155      AAVAAYEAWRQHGFPGAV
TH_2120|M.thermoresistible__bu      AAVAVYEAWRQHGFAGA-
MAB_3702|M.abscessus_ATCC_1997      AAIAAYEAWRQHDFAGSV
                                    **:*.******:.:.*